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VYDURA 75 mg Oral Lyophilized Orally Disintegrating Tablet/Liotab

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About the medicine

How to use VYDURA 75 mg ORAL LYOPHILIZED

Contents of the leaflet

  1. Introduction
  2. What is VYDURA and what is it used for
  3. What you need to know before you take VYDURA
  4. How to take VYDURA
  5. Possible side effects
  6. Storage of VYDURA
  7. Contents of the pack and further information

Introduction

Package Leaflet: Information for the Patient

VYDURA 75 mg Oral Lyophilisate

rimegepant

This medicinal product is subject to additional monitoring, which will allow for the quick identification of new safety information. You can help by reporting any side effects you may have. The last section of section 4 will tell you how to report side effects.

Read all of this leaflet carefully before you start taking this medicine, because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the Package Leaflet

  1. What is VYDURA and what is it used for
  2. What you need to know before you take VYDURA
  3. How to take VYDURA
  4. Possible side effects
  5. Storage of VYDURA
  6. Contents of the pack and further information

1. What is VYDURA and what is it used for

VYDURA contains the active substance rimegepant, which blocks the activity of a substance in the body called calcitonin gene-related peptide (CGRP). People with migraine may have high levels of CGRP. Rimegepant binds to the CGRP receptor, reducing the ability of CGRP to also bind to the receptor. This reduces the activity of CGRP and produces two effects:

  1. it can stop an active migraine attack, and
  2. it can reduce the number of migraine attacks that occur when taken preventively.

VYDURA is used to treat and prevent migraine attacks in adults.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take VYDURA

Do not take VYDURA

  • if you are allergic to rimegepant or any of the other ingredients of this medicine

(listed in section 6).

Warnings and precautions

Talk to your doctor or pharmacist before taking VYDURA if any of the following apply to you:

  • if you have severe liver problems;
  • if you have reduced kidney function or are on kidney dialysis.

During treatment with VYDURA, stop taking this medicine and tell your doctor immediately:

  • if you experience any symptoms of an allergic reaction, e.g. difficulty breathing or severe skin rash. These symptoms may occur several days after administration.

Children and adolescents

VYDURA should not be given to children and adolescents under 18 years of age, as it has not been studied in this age group.

Other medicines and VYDURA

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. This is because some medicines may affect the way VYDURA works or VYDURA may affect the way other medicines work.

The following is a list of examples of medicines that should be avoided when taking VYDURA:

  • itraconazole and clarithromycin (medicines used to treat fungal or bacterial infections);
  • ritonavir and efavirenz (medicines for treating HIV infections);
  • bosentan (medicine used to treat high blood pressure);
  • St. John's Wort (herbal remedy used to treat depression);
  • phenobarbital (medicine used to treat epilepsy);
  • rifampicin (medicine used to treat tuberculosis);
  • modafinil (medicine used to treat narcolepsy).

Do not take VYDURA more than once every 48 hours with:

  • fluconazole and erythromycin (medicines used to treat fungal or bacterial infections);
  • diltiazem, quinidine, and verapamil (medicines used to treat abnormal heart rhythm, chest pain [angina], or high blood pressure);
  • cyclosporin (medicine used to prevent organ rejection after a transplant).

Pregnancy and breastfeeding

If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. It is preferable to avoid the use of VYDURA during pregnancy, as the effects of this medicine on pregnant women are unknown.

If you are breastfeeding or plan to breastfeed, ask your doctor or pharmacist for advice before taking this medicine. You and your doctor will decide whether to use VYDURA during breastfeeding.

Driving and using machines

VYDURA is not expected to affect your ability to drive or use machines.

3. How to take VYDURA

Follow exactly the administration instructions of this medicine given by your doctor or pharmacist. If you are unsure, ask your doctor or pharmacist again.

How much to take

For the prevention of migraine, the recommended dose is one oral lyophilisate (75 mg of rimegepant) every two days.

For the treatment of a migraine attack once started, the recommended dose is one oral lyophilisate (75 mg of rimegepant) as needed, no more than once a day.

The maximum daily dose is one oral lyophilisate (75 mg of rimegepant) per day.

How to take this medicine

VYDURA is administered orally.

The oral lyophilisate can be taken with or without food or water.

Instructions:

Open with dry hands, remove protective film, and extract oral lyophilisate, do not push through film, instruction step 1

If you take more VYDURA than you should

Talk to your doctor or pharmacist or go to the hospital immediately. Take the medicine pack and this leaflet with you.

If you forget to take VYDURA

If you take VYDURA for the prevention of migraine and miss a dose, simply take the next dose at the usual time. Do not take a double dose to make up for forgotten doses.

If you have any other questions about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Stop using VYDURA and contact your doctor immediately if you have signs of an allergic reactionsuch as severe skin rash or difficulty breathing. Allergic reactions with VYDURA are rare (may affect up to 1 in 100 people).

A common side effect (may affect up to 1 in 10 people) is nausea.

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse, even if they are not listed in this leaflet. You can also report side effects directly via the Spanish Medicines Monitoring System: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of VYDURA

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. The expiry date is the last day of the month stated.

Do not store above 30°C. Store in the original blister to protect from moisture.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and further information

Composition of VYDURA

  • The active substance is rimegepant. Each oral lyophilisate contains 75 mg of rimegepant (as sulfate).
  • The other ingredients are: gelatin, mannitol, peppermint flavor, and sucralose.

Appearance and packaging of the product

The VYDURA 75 mg oral lyophilisates are white to off-white, circular, and have the symbol.

Package sizes:

  • 2 single-dose oral lyophilisates in a perforated blister.
  • 8 single-dose oral lyophilisates in perforated unit-dose blisters.
  • 16 single-dose oral lyophilisates in perforated unit-dose blisters.

Not all pack sizes may be marketed.

Marketing authorisation holder

Pfizer Europe MA EEIG

Boulevard de la Plaine 17

1050 Brussels

Belgium

Manufacturer

HiTech Health Limited

5-7 Main Street

Blackrock

Co. Dublin

A94 R5Y4

Ireland

Millmount Healthcare Limited

Block-7, City North Business Campus

Stamullen

Co. Meath

K32 YD60

Ireland

Pfizer Ireland Pharmaceuticals Unlimited Company

Little Connell

Newbridge

Co. Kildare

W12 HX57

Ireland

You can request more information about this medicine from the local representative of the marketing authorisation holder:

België/Belgique/Belgien

Luxembourg/Luxemburg

Pfizer NV/SA

Tél/Tel: +32 (0)2 554 62 11

Lietuva

Pfizer Luxembourg SARL filialas Lietuvoje

Tel. +370 5 251 4000

????????

??????? ?????????? ????, ???? ????????

???: +359 2 970 4333

Magyarország

Pfizer Kft.

Tel.: + 36 1 488 37 00

Ceská republika

Pfizer, spol. s r.o.

Tel: +420 283 004 111

Malta

Vivian Corporation Ltd.

Tel.: +356 21344610

Danmark

Pfizer ApS

Tlf.: +45 44 20 11 00

Nederland

Pfizer bv

Tel: +31 (0) 800 63 34 636

Deutschland

PFIZER PHARMA GmbH

Tel: +49 (0)30 550055-51000

Norge

Pfizer AS

Tlf: +47 67 52 61 00

Eesti

Pfizer Luxembourg SARL Eesti filiaal

Tel: +372 666 7500

Österreich

Pfizer Corporation Austria Ges.m.b.H.

Tel: +43 (0)1 521 15-0

Ελλ?δα

Pfizer Ελλ?ς Α.Ε.

Τηλ.: +30 210 6785800

Polska

Pfizer Polska Sp. z o.o.

Tel.: +48 22 335 61 00

España

Pfizer, S.L.

Tel: +34 91 490 99 00

Portugal

Laboratórios Pfizer, Lda.

Tel: +351 21 423 5500

France

Pfizer

Tél: +33 (0)1 58 07 34 40

România

Pfizer Romania S.R.L.

Tel: +40 (0) 21 207 28 00

Hrvatska

Pfizer Croatia d.o.o.

Tel: +385 1 3908 777

Slovenija

Pfizer Luxembourg SARL

Pfizer, podružnica za svetovanje s podrocja farmacevtske dejavnosti, Ljubljana

Tel.: +386 (0)1 52 11 400

Ireland

Pfizer Healthcare Ireland Unlimited Company

Tel: +1800 633 363 (toll free)

Tel: +44 (0)1304 616161

Slovenská republika

Pfizer Luxembourg SARL, organizacná zložka

Tel: + 421 2 3355 5500

Ísland

Icepharma hf.

Sími: +354 540 8000

Suomi/Finland

Pfizer Oy

Puh/Tel: +358 (0)9 430 040

Italia

Pfizer S.r.l.

Tel: +39 06 33 18 21

Sverige

Pfizer AB

Tel: +46 (0)8 550 520 00

Κ?προς

Pfizer Ελλ?ς Α.Ε. (Cyprus Branch)

Τηλ.: +357 22817690

Latvija

Pfizer Luxembourg SARL filiale Latvija

Tel: + 371 670 35 775

Date of last revision of this leaflet:04/2025.

Other sources of information

Detailed information on this medicine is available on the European Medicines Agency website: https://www.ema.europa.eu.

Online doctors for VYDURA 75 mg ORAL LYOPHILIZED

Discuss questions about VYDURA 75 mg ORAL LYOPHILIZED, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(20)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

Get VYDURA 75 mg ORAL LYOPHILIZED Prescription Online

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Electronic prescription sent to your email — valid across Spain.

Frequently Asked Questions

VYDURA 75 mg ORAL LYOPHILIZED requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in VYDURA 75 mg ORAL LYOPHILIZED is rimegepant. This information helps identify medicines with the same composition but different brand names.

VYDURA 75 mg ORAL LYOPHILIZED is manufactured by Pfizer Europe Ma Eeig. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether VYDURA 75 mg ORAL LYOPHILIZED is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy VYDURA 75 mg ORAL LYOPHILIZED in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

Other medicines with the same active substance (rimegepant) include AIMOVIG 140 mg SOLUTION FOR INJECTION IN A PRE-FILLED PEN, AIMOVIG 70 mg SOLUTION FOR INJECTION IN A PRE-FILLED PEN, AJOVY 225 mg PRE-FILLED SYRINGE SOLUTION FOR INJECTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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