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TROMBOBEN 1 mg/g CREAM

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use TROMBOBEN 1 mg/g CREAM

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Leaflet: Information for the user

Tromboben 1 mg/g cream

sodium pentosan polysulfate

Read the entire leaflet carefully before starting to use this medication, as it contains important information for you.

Follow the administration instructions of the medication contained in this leaflet or as indicated by your doctor or pharmacist.

  • Keep this leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are side effects not listed in this leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve after 5 days.

Contents of the leaflet:

  1. What is Tromboben and what is it used for
  2. What you need to know before starting to use Tromboben
  3. How to use Tromboben
  4. Possible side effects
  5. Storage of Tromboben
  6. Package contents and additional information

1. What is Tromboben and what is it used for

This medication is a cream for topical use that, when applied to the skin, improves blood flow. It belongs to the pharmacotherapeutic group of topical antivaricose agents.

Tromboben is indicated for:

  • Local symptomatic relief of superficial venous disorders such as heaviness and tightness in legs with varicose veins in adults.
  • Local symptomatic relief of superficial hematomas caused by bruises in adults and children over 1 year of age.
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2. What you need to know before starting to use Tromboben

Do not use Tromboben

  • If you are allergic (hypersensitive) to sodium pentosan polysulfate or any of the other components of this medication (listed in section 6).
  • If you have significant coagulation disorders.
  • Do not apply to mucous membranes, ulcers, and open or infected wounds.

Warnings and precautions

  • Consult your doctor or pharmacist before starting to use Tromboben
  • This medication is for topical use only (on the skin).
  • It should only be used on intact skin.
  • Eye contact should be avoided.
  • In case of venous problems caused by blood clots (such as thromboembolism), it is recommended to apply the product gently and without massage.
  • It should not be used for a long time or on very large areas of the skin.

Other medications and Tromboben

It is not recommended to apply other topical preparations to the same area.

Tell your doctor or pharmacist if you are taking, have recently taken, or may need to take any other medication.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medication.

You should not use Tromboben during pregnancy or breastfeeding unless your doctor tells you to do so.

Driving and using machines

The influence of Tromboben on the ability to drive and use machines is nil or insignificant.

Tromboben contains cetyl stearyl alcohol, sorbic acid, butylhydroxyanisole, polyoxyethylene castor oil, and propylene glycol.

Cetyl stearyl alcohol and sorbic acid may cause local skin reactions (such as contact dermatitis).

Butylhydroxyanisole may cause local skin reactions (such as contact dermatitis) or irritation of the eyes and mucous membranes.

Polyoxyethylene castor oil may cause skin reactions.

This medication contains 7.5 mg of propylene glycol per gram of cream. Propylene glycol may cause skin irritation.

3. How to use Tromboben

Follow the administration instructions of the medication contained in this leaflet or as indicated by your doctor or pharmacist. In case of doubt, consult your doctor or pharmacist again.

The recommended dose is:

  • Adults, adolescents, and children over 1 year of age:

Apply a thin layer of cream to the affected skin area, 3 or 4 times a day.

  • Children under 1 year of age.

Tromboben cream is not recommended for use in children under 1 year of age due to lack of information in this population.

Apply the preparation by gently massaging to facilitate penetration and wash your hands after each application. Generally, no dressing is needed, although it can be covered with a gauze or compress if necessary.

If symptoms worsen or last more than 5 days, or if irritation or worsening occurs, discontinue application and consult your doctor.

If you think the effect of Tromboben is too strong or too weak, tell your doctor or pharmacist.

If you use more Tromboben than you should

Using more cream than recommended may cause skin irritation.

In case of overdose or accidental ingestion, consult your doctor or pharmacist or call the Toxicology Information Service. Phone 915 62 04 20, indicating the medication and the amount ingested.

If you stop treatment with Tromboben

If you have any other doubts about the use of this medication, ask your doctor or pharmacist.

Medicine questions

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4. Possible side effects

Like all medications, this medication can cause side effects, although not everyone will experience them.

The following side effects have been reported in post-marketing experience. The frequency is defined as: very common (may affect more than 1 in 10 people), common (may affect up to 1 in 10 people), uncommon (may affect up to 1 in 100 people), rare (may affect up to 1 in 1,000 people), very rare (may affect up to 1 in 10,000 people), frequency not known (cannot be estimated from available data).

Immune system disorders

Very rare: allergic reactions at the application site, which may manifest as itching and irritation, and disappear when treatment is discontinued.

Reporting side effects

If you experience any side effects, consult your doctor or pharmacist, even if they are possible side effects not listed in this leaflet. You can also report them directly through the Spanish Medication Surveillance System for Human Use: www.notificaRAM.es. By reporting side effects, you can contribute to providing more information on the safety of this medication.

5. Storage of Tromboben

Keep out of sight and reach of children.

Keep the tube perfectly closed.

Do not use this medication after the expiration date shown on the box or tube after EXP. The expiration date is the last day of the month indicated.

Medications should not be thrown away in drains or trash. Deposit the packaging and medications you no longer need at the SIGRE Point in the pharmacy. If in doubt, ask your pharmacist how to dispose of the packaging and medications you no longer need. This will help protect the environment.

6. Package contents and additional information

Composition of Tromboben 1 mg/g cream

  • The active ingredient is sodium pentosan polysulfate. Each gram of cream contains 1 mg of sodium pentosan polysulfate.
  • The other components (excipients) are cetyl stearyl alcohol, sodium cetyl sulfate (E-540), polyoxyethylene castor oil, butylhydroxyanisole (E-320), citric acid (E-300), potassium phosphate, decyl oleate, sorbitol (E-420), propylene glycol (E-1520), sorbic acid (E-200), levulinic acid, phenoxyethanol, guaiazulene, thymol, and purified water.

Appearance of the product and package contents

White or white-yellowish cream with a bluish tint and characteristic odor.

It is presented in tubes containing 30 g and 60 g of cream.

Marketing authorization holder and manufacturer

Marketing authorization holder

Teva Pharma, S.L.U

Anabel Segura, 11. Edificio Albatros B - 1ª planta.

28108 Alcobendas. Madrid. Spain

Manufacturer

Infarmade, S.L

C/ Torre de los Herberos 35.

Polígono Industrial Carretera de la Isla

41703 Dos Hermanas. Sevilla

Spain

Date of the last revision of this leaflet:June 2018

Detailed information about this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for TROMBOBEN 1 mg/g CREAM

Discuss questions about TROMBOBEN 1 mg/g CREAM, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
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He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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€58
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Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
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  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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€70
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Doctor

Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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€55

Frequently Asked Questions

Is a prescription required for TROMBOBEN 1 mg/g CREAM?
TROMBOBEN 1 mg/g CREAM does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in TROMBOBEN 1 mg/g CREAM?
The active ingredient in TROMBOBEN 1 mg/g CREAM is pentosan polysulfate sodium. This information helps identify medicines with the same composition but different brand names.
Who manufactures TROMBOBEN 1 mg/g CREAM?
TROMBOBEN 1 mg/g CREAM is manufactured by Teva Pharma S.L.U.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of TROMBOBEN 1 mg/g CREAM online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether TROMBOBEN 1 mg/g CREAM is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to TROMBOBEN 1 mg/g CREAM?
Other medicines with the same active substance (pentosan polysulfate sodium) include THROMBOCID 1mg/g OINTMENT, THROMBOCID FORTE 5 mg/g OINTMENT, TROMBOBEN FORTE 5 mg/g CREAM. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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