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TOSIVY SYRUP

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About the medicine

How to use TOSIVY SYRUP

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

PACKAGE LEAFLET

Package Leaflet: Information for the User

Tosivy Syrup

Dry extract of Hedera helixL. (ivy)

Read the entire package leaflet carefully before starting to take this medicine, as it contains important information for you.

Follow the administration instructions of the medicine contained in this package leaflet or as indicated by your doctor or pharmacist.

  • Keep this package leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are side effects not listed in this package leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve after 7 days.

Contents of the package leaflet

  1. What is Tosivy and what is it used for
  2. What you need to know before taking Tosivy
  3. How to take Tosivy
  4. Possible side effects

5 Conservation of Tosivy

  1. Contents of the packaging and additional information

1. What is Tosivy and what is it used for

Tosivy is a traditional herbal medicinal product developed from the dry extract of Hedera helix(ivy) leaves used as an expectorant for productive cough.

It is indicated for adults, adolescents, and children over 2 years of age for use in specific indications based on traditional use.

Doctor consultation

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2. What you need to know before taking Tosivy

Do not take Tosivy

If you are allergic to ivy (Hedera helixL.), to plants of the Araliaceaefamily, or to any of the other components of this medicine (listed in section 6).

Do not administer to children under 2 years of age, as there is a risk that expectorants may worsen respiratory symptoms.

Warnings and precautions

Consult your doctor or pharmacist before starting to take Tosivy.

If dyspnea, fever, and bloody or purulent expectorations occur, consult a doctor immediately.

Patients with gastritis or gastric ulcer should use this medicine with caution.

Tosivy contains a plant extract, which may cause the syrup to be slightly cloudy.

Children

In the case of persistent or recurrent cough in children, consult a doctor before starting treatment.

Warning about excipients:

Tosivy contains sorbitol(E 420): 320 milligrams per milliliter of syrup.

If your doctor has told you that you have an intolerance to certain sugars, consult with them before taking this medicine.

Use in patients with impaired renal and/or hepatic function

If you have renal or hepatic insufficiency, consult your doctor or pharmacist before taking the medicine. There are no data for dosage recommendations in these patients.

Taking Tosivy with other medicines

Inform your doctor or pharmacist if you are taking, have recently taken, or may need to take any other medicine.

No interaction of Tosivy with other medicines is known.

Concomitant use with other antitussives such as codeine or dextromethorphan is not recommended without prior medical consultation.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Pregnancy:

There are no adequate and well-controlled studies in pregnant women, so its administration is not recommended.

Breastfeeding:

There is no information on the passage of the components of this medicine into breast milk, so its administration is not recommended in breastfeeding women.

Driving and using machines

No studies have been conducted on the ability to drive and use machines.

3. How to take Tosivy

Follow the administration instructions of the medicine contained in this package leaflet or as indicated by your doctor or pharmacist. In case of doubt, ask your doctor or pharmacist.

The recommended dose is:

Adults and adolescents over 12 years of age: 3-4 ml of syrup, 2 or 3 times a day (which corresponds to 44.4 mg or 88.8 mg of ivy extract)

Children from 6 to 11 years of age: 2.5 ml of syrup, 2 or 3 times a day (which corresponds to 37 mg or 55.5 mg of extract)

Children from 2 to 5 years: 1.5 ml, 3 times a day (which corresponds to 33.3 mg of extract)

For administration to children between 2 and 4 years of age with persistent or recurrent cough, medical diagnosis is required before starting treatment.

The use of Tosivy in children under 2 years of age is contraindicated (see section 4.3).

Treatment duration

If symptoms persist during the use of the medicine for more than one week, consult a doctor or pharmacist.

Tosivy is taken/administered orally. Shake the bottle well before use. To ensure that you always take the recommended dose, you must use the dosing syringe, graduated every 0.5 ml up to 5 ml, included in the packaging.

If you take more Tosivy than you should

Do not exceed the recommended daily dose.

In case of taking more Tosivy than you should, or in case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 915 620 420, indicating the medicine and the amount ingested.

Taking higher amounts than recommended may cause nausea, vomiting, diarrhea, and nervousness.

If you forget to take Tosivy

Do not take a double dose to make up for forgotten doses.

If you interrupt treatment with Tosivy

If you have any other doubts about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

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Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everyone gets them.

Gastrointestinal reactions (nausea, vomiting, diarrhea) have been described. The frequency is unknown.

Allergic reactions (urticaria, skin rash, dyspnea, anaphylactic reaction) have been described. The frequency is unknown.

If you notice any of the above-mentioned side effects, particularly symptoms of allergy, stop taking the medicine and consult your doctor.

If any other type of adverse reactions not mentioned above occurs, consult your doctor or pharmacist.

Reporting of side effects

If you experience any type of side effect, consult your doctor, pharmacist, or nurse, even if it is a possible side effect not listed in this package leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can contribute to providing more information on the safety of this medicine.

5. Conservation of Tosivy

Keep this medicine out of the sight and reach of children.

Store below 30 °C.

Do not use this medicine after the expiration date stated on the carton and label after the abbreviation CAD. The expiration date is the last day of the month indicated.

Once the packaging is opened, the validity will be 3 months. Remember to record the opening date on the medicine packaging.

Medicines should not be disposed of via wastewater or household waste. Deposit the packaging and medicines you no longer need at the SIGRE point in the pharmacy. In case of doubt, ask your pharmacist how to dispose of the packaging and medicines you no longer need. This way, you will help protect the environment.

6. Contents of the packaging and additional information

Composition of Tosivy

1 ml of syrup contains 7.4 mg of dry extract of Hedera helixL. (ivy) leaves, (4.0 – 8.0:1) extraction solvent ethanol 30% m/m.

  • The active principle is: dry extract of Hedera helixL. (ivy) leaves.
  • The other components (excipients) are: potassium sorbate, non-crystallizable liquid sorbitol 70% (320 mg per ml), propylene glycol, xanthan gum, citric acid monohydrate, purified water.

Appearance of the product and contents of the packaging

The medicine is presented in type III amber glass bottles with 100 ml of syrup. Child-resistant closure made of high-density polyethylene (HDPE).

Dosing syringe made of low-density polyethylene (LDPE) of 5 ml, graduated every 0.5 ml, with a plunger made of polyethylene (PE).

Marketing authorization holder

Laboratorios Lorien

Av. Josep Tarradellas, 8, Ático 1ª

08029 Barcelona

Spain

Manufacturer

Instituto Universitario de Ciencia y Tecnología, S.A.

c/ Álvarez de Castro, 63

08100 Mollet del Vallès

Spain

Date of the last revision of this package leaflet:October 2019

Detailed information about this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es/)

Online doctors for TOSIVY SYRUP

Discuss questions about TOSIVY SYRUP, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (29)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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5.0 (29)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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5.0 (2)
Doctor

Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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5.0 (2)
Doctor

Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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Frequently Asked Questions

Is a prescription required for TOSIVY SYRUP?
TOSIVY SYRUP does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in TOSIVY SYRUP?
The active ingredient in TOSIVY SYRUP is Hederae helicis folium. This information helps identify medicines with the same composition but different brand names.
Who manufactures TOSIVY SYRUP?
TOSIVY SYRUP is manufactured by Laboratorios Lorien S.L.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of TOSIVY SYRUP online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether TOSIVY SYRUP is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to TOSIVY SYRUP?
Other medicines with the same active substance (Hederae helicis folium) include ABRILAR SYRUP, ACTUATOS 35 mg ORAL SOLUTION IN SACHETS, ACTUATOS 7 mg/ml SYRUP. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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