This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.

How to use VELTASSA 8.4 g ORAL SUSPENSION POWDER

Introduction

Package Leaflet: Information for the Patient

Veltassa 1g oral powder for suspension

Veltassa 8.4 g oral powder for suspension

Veltassa 16.8 g oral powder for suspension

Veltassa 25.2 g oral powder for suspension

patiromer (as patiromer calcium sorbitex)

Read this entire leaflet carefully before you or your child start taking this medicine, as it contains important information for you.

Keep this leaflet, as you may need to read it again.
If you have any further questions, ask your doctor or pharmacist.
This medicine has been prescribed to you or your child only. Do not give it to others, as it may harm them, even if their symptoms are the same as yours.
If you or your child experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.

Contents of the package leaflet

What is Veltassa and what is it used for
What you need to know before taking Veltassa
How to take Veltassa
Possible side effects
Storage of Veltassa
Package contents and further information

1. What is Veltassa and what is it used for

Veltassa is a medicine that contains patiromer as the active substance.

This medicine is used to treat adults and adolescents from 12 to 17 years of age with high levels of potassium in the blood.

Too much potassium in the blood can affect how nerves control muscles, which can cause weakness or even paralysis. High levels of potassium can also cause an abnormal heartbeat, which can have serious effects on your or your child's heart rhythm.

This medicine works by binding to potassium in the intestine, which prevents potassium from entering the bloodstream and reduces potassium levels in the blood to restore normal levels.

2. What you need to know before taking Veltassa

Do not take Veltassa

If you or your child are allergic to patiromer or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Talk to your doctor or pharmacist before starting to use Veltassa if you or your child:

have swallowing problems. If you cannot swallow the medicine, it will not work.
have severe stomach or intestinal problems. This medicine can cause constipation or diarrhea in some patients.
have had major stomach or intestinal surgery. This medicine works through the intestine, so major surgery in this area may reduce its effect.

The level of magnesium in the blood may decrease when taking this medicine. Your doctor will monitor the magnesium level during treatment with this medicinefor at least 1 month and may prescribe a magnesium supplement if necessary.

Children and adolescents

Do not give this medicineto children under 12 years of age, as it has not been studied in this age group.

Other medicines and Veltassa

Tell your doctor or pharmacist if you or your child are taking, have recently taken, or might take any other medicines.

This medicine may reduce the absorption of certain medicines or interact with them if taken orally and at the same time, for example:

ciprofloxacin: a medicine to treat bacterial infections
levothyroxine: a medicine to treat thyroid hormone deficiency
metformin: a medicine to treat diabetes
mycophenolate mofetil: a medicine to prevent the body from rejecting a transplanted organ
quinidine: a medicine to treat irregular heartbeat
telmisartan, bisoprolol, carvedilol, nebivolol: medicines to treat high blood pressure and heart problems.

Use all oral medicines at least 3 hours before or after using Veltassa. Some medicines are not affected by the use of Veltassa, so your doctor or pharmacist may give you different instructions depending on the medicines you or your child are taking. Talk to your doctor or pharmacist if you are unsure.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, talk to your doctor or pharmacist before using this medicine.

Use this medicineduring pregnancy and breastfeeding only if your doctor considers it necessary.

Driving and using machines

The influence of this medicineon the ability to drive and use machines is negligible or nonexistent.

Veltassa contains sorbitol

The sorbitol content is approximately 4 g (10.4 kcal) per 8.4 g of patiromer and 0.5 g (1.2 kcal) per 1 g of patiromer. Sorbitol is a source of fructose. If your doctor has told you or your child that you have an intolerance to certain sugars, or you have been diagnosed with hereditary fructose intolerance (HFI), a rare genetic disorder in which the patient cannot break down fructose, talk to your doctor before using this medicine. Sorbitol can cause gastrointestinal upset and a mild laxative effect.

Veltassa contains calcium

If your doctor has told you or your child to limit calcium in your diet, talk to your doctor before using this medicine. Your doctor will monitor the calcium level during treatment with this medicine for at least 1 month.

3. How to take Veltassa

Follow the instructions for use of this medicine exactly as indicated by your doctor or pharmacist. If you are unsure, talk to your doctor or pharmacist again.

This medicine is given once a day. The recommended initial dose of this medicine varies with age. Several sachets may be used to achieve the desired dose. Your doctor may adjust the daily dose based on your or your child's blood potassium level, up to a maximum dose of 25.2 g per day.

Adults

Initial dose:8.4 g of patiromer (the contents of one 8.4 g sachet) once a day.

Adolescents from 12 to 17 years of age

Initial dose:4 g of patiromer (the contents of four 1 g sachets) once a day. Switch to 8.4 g patiromer sachets if doses above 7 g are needed.

Your doctor will determine the duration of treatment based on your blood potassium level.

Use this medicine at least 3 hours before or after taking other oral medicines, unless your doctor or pharmacist tells you otherwise.

Method of administration

Before taking this medicine, it must be mixed with water as described below. The volume of water depends on your dose:

1 g of patiromer: 10 ml (2 teaspoons)
2 g of patiromer: 20 ml (4 teaspoons)
3 g of patiromer: 30 ml (6 teaspoons)
4 g of patiromer: 40 ml (3 tablespoons)
More than 4 g of patiromer: 80 ml (6 tablespoons)

Prepare the mixture by following these steps:

Pour half of the water into a glass, add the required number of Veltassa sachets, and mix.
Add the remaining half of the water and mix well. The powder does not dissolve but forms a suspension that can be felt as granular.
You can add more water to the mixture to help you swallow the medicine. Note that with a larger volume, the powder may settle more quickly.
Drink the mixture within 1 hour of preparation. If powder remains in the glass after drinking the contents, add more water, mix, and drink immediately. You may need to do this again to ensure you have taken all the powder.

If you prefer, you can use the following liquids or soft foods instead of water to prepare the mixture, following the same steps as above: apple juice, cranberry juice, pineapple juice, orange juice, grape juice, or pear juice, apricot or peach nectar, yogurt, milk, thickener (e.g., cornstarch), applesauce, chocolate or vanilla pudding.

If you use these liquids and soft foods, you or your child should follow the recommendations on potassium intake for your diet. If you are unsure, ask your doctor or pharmacist.

Only drink cranberry juice in small amounts (less than 400 ml per day), as it may affect other medicines.

Use the prepared Veltassa suspension with or without food, preferably at the same time each day. Neverheat this medicine or add it to hot foods or liquids.

Do not takethis medicine as dry powder.

If you use a nasogastric tube or a percutaneous endoscopic gastrostomy (PEG) tube, follow the steps described above to prepare the suspension for oral administration. For doses up to 8.4 g of patiromer, use the volume described above. For doses above 8.4 g and up to 16.8 g of patiromer, use a total volume of 160 ml (12 tablespoons), and for doses above 16.8 g and up to 25.2 g of patiromer, use a total volume of 240 ml (18 tablespoons). These volumes ensure that the suspension flows easily through the tubes.

Polyurethane, silicone, and polyvinyl chloride tubes can be used. The recommended tube diameter is 2.17 mm (6.5 Fr) or larger. After administration of the suspension, the tube should be flushed with water. Follow the manufacturer's instructions for the tube.

If you take more Veltassa than you should

Stop using this medicine and talk to your doctor or pharmacist immediately.

If you forget to take Veltassa

If you or your child forget to take a dose, take it as soon as possible on the same day. Do not take a double dose to make up for forgotten doses. If you forget more than one dose, contact your doctor.

If you stop treatment with Veltassa

Do not stop using the medicine without your doctor's approval, as the level of potassium in the blood may increase.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Stop taking the medicine and seek urgent medical attention if you notice any of the following side effects:

Frequency not known,cannot be estimated from the available data:

allergic reactions: symptoms include skin rash, hives, swelling of lips, tongue, or throat

The following additional side effects have been reported:

Common,may affect up to 1 in 10 people:

constipation
diarrhea
abdominal pain
nausea
gas
low magnesium level in the blood (observed in laboratory tests)

Uncommon, may affect up to 1 in 100 people:

vomiting

There have also been reports of constipation, diarrhea, and gas in children and adolescents from 6 to 17 years of age.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this leaflet. You can also report side effects directly through the national reporting system listed in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Veltassa

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date stated on the carton or sachet after "EXP". The expiry date is the last day of the month stated.

Store and transport refrigerated (between 2°C and 8°C).

Once you have received this medicine, it can be stored below 25°C for up to 6 months.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Package contents and further information

Composition of Veltassa

The active substance is patiromer (as patiromer calcium sorbitex).
Veltassa 1 g oral powder for suspension: each sachet contains 1 g of patiromer.
Veltassa 8.4 g oral powder for suspension: each sachet contains 8.4 g of patiromer.
Veltassa 16.8 g oral powder for suspension: each sachet contains 16.8 g of patiromer.
Veltassa 25.2 g oral powder for suspension: each sachet contains 25.2 g of patiromer.

The other ingredient (excipient) is xanthan gum (for more information on sorbitol, see section 2).

Appearance of Veltassa and package contents

The powder for oral suspension is white to light brown in color, with isolated white particles.

Veltassa 1 g is available in packs of 60 sachets.

Veltassa 8.4 g is available in packs of 30, 60, or 90 sachets and in multipacks containing 3 packs of 30 sachets each.

Veltassa 16.8 g and 25.2 g are available in packs of 30, 60, or 90 sachets.

Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Marketing authorization holder

Vifor Fresenius Medical Care Renal Pharma France

100–101 Terrasse Boieldieu

Tour Franklin La Défense 8

92042 Paris La Défense Cedex

France

Manufacturer

Vifor France

100–101 Terrasse Boieldieu

Tour Franklin La Défense 8

92042 Paris La Défense Cedex

France

Date of last revision of this leaflet:06/2024

Other sources of information

Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu.

How much does VELTASSA 8.4 g ORAL SUSPENSION POWDER cost in Spain ( 2025)?

The average price of VELTASSA 8.4 g ORAL SUSPENSION POWDER in November, 2025 is around 247.43 EUR. Prices may vary depending on the region, pharmacy, and whether a prescription is required. Always check with a local pharmacy or online source for the most accurate information.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

12+ years of clinical experience in university hospitals in Germany and Spain.
International education: Ukraine – Germany – Spain.
Member of the German Society of Surgeons (BDC).
Certified in radiological diagnostics and robotic surgery.
Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

VELTASSA 8.4 g ORAL SUSPENSION POWDER

Yevgen Yakovenko

Antonio Cayatte

Yevgen Yakovenko

Antonio Cayatte