Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

12+ years of clinical experience in university hospitals in Germany and Spain.
International education: Ukraine – Germany – Spain.
Member of the German Society of Surgeons (BDC).
Certified in radiological diagnostics and robotic surgery.
Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.

How to use Velphoro 500 mg chewable tablets

Introduction

Package Leaflet: Information for the User

Velphoro 500 mg Chewable Tablets

iron as sucroferric oxyhydroxide

Read this package leaflet carefully before you start taking this medicine, because it contains important information for you.

Keep this package leaflet, you may need to read it again.
If you have any further questions, ask your doctor or pharmacist.

This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this package leaflet. See section 4.

Contents of the package leaflet

What is Velphoro and what is it used for
What you need to know before you take Velphoro
How to take Velphoro

Possible side effects
Storage of Velphoro

Contents of the pack and further information

1. What is Velphoro and what is it used for

Velphoro is a medicine that contains the active substance sucroferric oxyhydroxide, which consists of iron, sugar (sucrose), and starches.

This medicine is used to control high levels of phosphate in the blood (hyperphosphataemia) in:

•

adults undergoing haemodialysis or peritoneal dialysis (procedures to remove toxic substances from the blood) due to chronic kidney disease;
children from 2 years and adolescents with chronic kidney disease in stages 4 and 5 (severe reduction in kidney function) or on dialysis.

Excess phosphate in the blood can cause calcium deposits in tissues (calcification), which can lead to stiffness of blood vessels, making it difficult to pump blood throughout the body. It can also cause calcium deposits in soft tissues and bones, leading to effects such as red eyes, skin itching, and bone pain.

This medicine works by binding phosphate from food in the digestive tract (stomach and intestines), which reduces the amount of phosphate that can be absorbed into the bloodstream and, therefore, decreases phosphate levels in the blood.

2. What you need to know before you take Velphoro

Do not take Velphoro

If you are allergic to sucroferric oxyhydroxide or any of the other ingredients of this medicine (listed in section 6).
If you have suffered from abnormal iron accumulation in organs (haemochromatosis).

If you suffer from any other disorder associated with excess iron.

If you are not sure, consult your doctor before taking this medicine.

Warnings and precautions

Consult your doctor or pharmacist before starting to take Velphoro:

If you have suffered from peritonitis, an inflammation of the peritoneum (the thin tissue that lines the inner wall of the abdomen), in the last 3 months.
If you suffer from significant stomach and/or liver disorders.
If you have undergone major stomach and/or intestinal surgery.

If you are not sure if any of these conditions apply to your case, consult your doctor or pharmacist before taking this medicine.

This medicine may cause black stools. Any possible bleeding in the digestive tract (stomach and intestine) may be hidden due to black stools. If you have black stools and also experience symptoms such as increasing tiredness or difficulty breathing, contact your doctor immediately(see section 4).

Children and adolescents

The safety and efficacy of Velphoro have not been established in children under 2 years. Therefore, this medicine is not recommended for use in children under 2 years.

Other medicines and Velphoro

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

If you are taking any other medicine that is known to be affected by iron (e.g. medicines containing alendronate as the active substance (used for certain bone disorders) or doxycycline (an antibiotic)), or that may be affected by iron (e.g. medicines containing levothyroxine as the active substance (used to treat thyroid function disorders)), make sure to take this medicine at least one hour before taking Velphoro or at least two hours after. In case of doubt, consult your doctor.

Pregnancy and breastfeeding

There is no information on the effects of this medicine when taken during pregnancy or breastfeeding. If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Your doctor will decide with you whether you should use Velphoro during pregnancy or breastfeeding.

Your doctor will advise you whether to take Velphoro during pregnancy, based on the assessment of the risks and benefits of its use.

If you are breastfeeding, your doctor will discuss with you whether you should continue breastfeeding or treatment with Velphoro, taking into account the benefits of treatment with Velphoro for you and the benefits of breastfeeding for your child.

It is unlikely that this medicine will pass into breast milk.

Driving and using machines

The influence of this medicine on the ability to drive or use tools or machines is negligible.

Velphoro contains sucrose and starches (carbohydrates)

If your doctor has told you that you have an intolerance to some sugars, consult them before taking this medicine.

This medicine may damage teeth.

This medicine contains starches. If you have diabetes, you should note that one chewable tablet of this medicine is equivalent to approximately 1.4 g of carbohydrates (equivalent to 0.116 bread units).

3. How to take Velphoro

Follow exactly the administration instructions of this medicine given by your doctor or pharmacist. If you are not sure, consult your doctor or pharmacist again.

The recommended initial dose: in children from 6 to less than 9 years is 750 mg of iron per day*;
in children and adolescents from 9 to 12 years is 1,000 mg of iron (2 tablets) per day; and
for adults and adolescents over 12 years is 1,500 mg of iron per day (3 tablets).

Your doctor may adjust the dose during the course of treatment, based on the level of phosphate in your blood.

The maximum recommended dose:

in children from 6 to less than 9 years is 2,500 mg of iron (5 tablets) per day;
in children, adolescents between 9 and 18 years, and adults is 3,000 mg of iron (6 tablets) per day.

Velphoro is also available as an oral powder in sachets (equivalent to 125 mg of iron) for use in children between 2 and less than 12 years.

Method of administration

This medicine should only be taken orally.
Take the tablet during a meal and chew it (the tablet can be crushed to facilitate swallowing, if necessary). DO NOT swallow the tablet whole.
Divide the daily amount of tablets into the different meals of the day.

During treatment with Velphoro, you should follow the recommended diet and treatments indicated by your doctor, such as calcium supplements, vitamin D3, or calcimimetics (used to treat parathyroid gland problems).

Only for blisters:

Separate the blister by the pre-cut line.
Pull the paper by the corner.

Press the tablet to pass through the aluminium foil.

If you take more Velphoro than you should

If you have accidentally taken too many tablets, do not take any more and consult your doctor or pharmacist immediately.

If you forget to take Velphoro

If you have missed a dose, take the next dose at the usual time with a meal. Do not take a double dose to make up for forgotten doses.

If you stop taking Velphoro

Do not stop taking the medicine before consulting your doctor or pharmacist, as the level of phosphate in the blood may increase (see section 1).

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Black stools may occur very frequently in patients taking Velphoro. If you also experience symptoms such as increasing tiredness or difficulty breathing, contact your doctor immediately (see section 2 "Warnings and precautions").

The following side effects have been reported in patients taking Velphoro:

Very common(may affect more than 1 in 10 people): diarrhoea (usually occurs from the start of treatment and improves over time).

Common(may affect up to 1 in 10 people): nausea, constipation, vomiting, indigestion, stomach and intestinal pain, flatulence, change in tooth colour, change in taste.

Uncommon(may affect up to 1 in 100 people): inflammation (abdominal distension), stomach inflammation, abdominal discomfort, difficulty swallowing, acid reflux, change in tongue colour, high or low calcium levels in the blood observed in laboratory tests, tiredness, itching, rash, headache, shortness of breath.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this package leaflet. You can also report side effects directly via the national reporting system listed in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Velphoro

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton, bottle, or blister after "EXP". The expiry date is the last day of the month stated.

After first opening of the bottle, the chewable tablets can be used for 90 days.

Store in the original package to protect from moisture.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and further information

Composition of Velphoro

The active substance is iron as sucroferric oxyhydroxide, also known as a mixture of polynuclear iron (III) oxyhydroxide, sucrose, and starches. Each chewable tablet contains 500 mg of iron as sucroferric oxyhydroxide. Each tablet also contains 750 mg of sucrose and 700 mg of starches. See section 2 for more information on sucrose and starches.
The other ingredients are wild berry flavour, neohesperidin dihydrochalcone, magnesium stearate, and anhydrous colloidal silica.

Appearance of the product and pack contents

The chewable tablets are brown, circular with PA500 engraved on one side. The tablets are 20 mm in diameter and 6.5 mm in thickness.

The tablets are packaged in high-density polyethylene bottles with a child-resistant polypropylene cap and an induction-sealed liner or in child-resistant aluminium blisters.

Velphoro is available in packs of 30 or 90 chewable tablets. Multipacks are available in cartons with 3 packs of 30 x 1 chewable tablet each.

Not all pack sizes may be marketed.

Marketing authorisation holder

Vifor Fresenius Medical Care Renal Pharma France 100–101 Terrasse Boieldieu Tour Franklin La Défense 8

92042 Paris la Défense Cedex

France

Manufacturer

Vifor France

100–101 Terrasse Boieldieu

Tour Franklin La Défense 8

92042 Paris la Défense Cedex

France

You can obtain further information on this medicine by contacting the marketing authorisation holder.

Date of last revision of this package leaflet:

Detailed information on this medicine is available on the European Medicines Agency (EMEA) website: http://www.emea.europa.eu/.

How much does Velphoro 500 mg chewable tablets cost in Spain ( 2025)?

The average price of Velphoro 500 mg chewable tablets in December, 2025 is around 178.47 EUR. Prices may vary depending on the region, pharmacy, and whether a prescription is required. Always check with a local pharmacy or online source for the most accurate information.

Velphoro 500 mg chewable tablets

Yevgen Yakovenko

Roman Raevskii

Yevgen Yakovenko

Roman Raevskii