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TIORFAN NIÑOS 30 mg ORAL SUSPENSION GRANULES

TIORFAN NIÑOS 30 mg ORAL SUSPENSION GRANULES

Ask a doctor about a prescription for TIORFAN NIÑOS 30 mg ORAL SUSPENSION GRANULES

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Doctor

Yevgen Yakovenko

General surgery11 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use TIORFAN NIÑOS 30 mg ORAL SUSPENSION GRANULES

Introduction

Leaflet: information for the user

Tiorfan Children 30 mg granules for oral suspension

racecadotril

Read the entire leaflet carefully before starting to take the medicine.

  • Keep this leaflet, as you may need to read it again.
  • If you have any questions, ask your doctor or pharmacist.
  • This medicine has been prescribed to your child and should not be given to others, even if they have the same symptoms as your child, as it may harm them.
  • If your child experiences side effects, consult your doctor or pharmacist, even if they are side effects not listed in this leaflet. See section 4.

Contents of the leaflet:

  1. What is Tiorfan and what is it used for
  2. What you need to know before taking Tiorfan
  3. How to take Tiorfan
  4. Possible side effects
  5. Storage of Tiorfan
  6. Package contents and additional information

1. What is Tiorfan and what is it used for

Tiorfan is a medicine for the treatment of diarrhea.

Tiorfan is used to treat the symptoms of acute diarrhea in children over 3 months. It should be used in conjunction with abundant fluid intake and usual dietary measures, when these measures alone are insufficient to control diarrhea, and when the causes of diarrhea cannot be treated.

If causal treatment is possible, racecadotril may be administered as complementary treatment.

2. What you need to know before taking Tiorfan

Do not use Tiorfan

  • If your child is allergic to racecadotril or any of the other components of Tiorfan (listed in section 6).
  • If your doctor has told you that your child has intolerance to some sugars, ask your doctor before giving Tiorfan to your child.
  • If your child has ever developed a severe skin rash or skin peeling, blisters, and/or sores in the mouth after taking racecadotril.

Warnings and precautions

Consult your doctor or pharmacist before starting to give Tiorfan to your child if:

  • your child is under 3 months,
  • there is blood or pus in your child's stool and if they have a fever. The cause of their diarrhea may be a bacterial infection that needs to be treated by your doctor,
  • your child suffers from chronic diarrhea or diarrhea caused by antibiotics,
  • your child suffers from prolonged or uncontrolled vomiting,
  • your child has kidney disease or insufficient liver function,
  • your child has diabetes (see "Important information about some of the components of Tiorfan").

Racecadotril, the active ingredient of Tiorfan, may cause an allergic reaction called angioedema, which can cause swelling of the face, lips, throat, or tongue. If your child experiences these side effects, stop treatment immediately and contact your doctor. Swelling can occur at any time during treatment with this product.

The concomitant use of this product and some other medicines may increase the risk of angioedema (see "Other medicines and Tiorfan").

Skin reactions have been reported with the use of this product. In most cases, they are mild and do not require treatment. In some cases, severe skin reactions may occur. In these cases, treatment should be stopped immediately and the child should not be treated with racecadotril again.

Severe skin reactions, including drug reaction with eosinophilia and systemic symptoms (DRESS), have been reported in association with treatment with racecadotril. Discontinue the use of racecadotril and seek immediate medical attention if you notice any of the symptoms related to these severe skin reactions described in section 4.

Using Tiorfan with other medicines

Tell your doctor if your child is using, has recently used, or may need to use any other medicine.

Especially tell your doctor if your child is using any of the following medicines, as they may increase the risk of side effects (see "Warnings and precautions"):

  • ACE inhibitor (e.g., perindopril or ramipril) used to lower blood pressure or treat heart failure.
  • Angiotensin II receptor antagonists (e.g., candesartan or irbesartan) used to treat high blood pressure and heart failure.
  • Sacubitril, used to treat heart failure.
  • Some immunosuppressants (e.g., sirolimus or everolimus).
  • Some antidiabetics (e.g., sitagliptin or vildagliptina).
  • Estramustine, used to treat cancer.
  • Alteplase, used to treat blood clots.

Pregnancy and breastfeeding

The use of Tiorfan is not recommended during pregnancy and breastfeeding.

Consult your doctor or pharmacist before using this medicine.

Driving and using machines

Tiorfan has little or no effect on the ability to drive or operate machinery.

Tiorfan contains sucrose

Tiorfan contains approximately 3 g of sucrose per sachet.

If your doctor has told you that your child has intolerance to some sugars, ask your doctor before giving Tiorfan to your child.

In children with diabetes, the amount of sucrose ingested with Tiorfan should be taken into account in the child's total daily sugar intake.

3. How to take Tiorfan

Follow the instructions for administering Tiorfan indicated by your doctor. In case of doubt, consult your doctor or pharmacist again.

Tiorfan is presented in the form of granules.

The granules can be added to food or mixed in a glass of water or in the baby bottle. Mix well and give it to your child immediately.

The recommended daily dose depends on your child's weight: 1.5 mg/kg per dose (corresponding to 1-2 sachets), three times a day at regular intervals.

In children weighing 13 to 27 kg: one sachet per dose.

In children weighing over 27 kg: approximately two sachets per dose.

Your doctor will indicate the duration of treatment with Tiorfan. Treatment should be continued until two normal stools are produced, without exceeding 7 days.

To compensate for the loss of fluid due to your child's diarrhea, this medicine should be used in conjunction with adequate fluid and electrolyte replacement. The best replacement of fluids and salts is achieved with an oral rehydration solution (please ask your doctor or pharmacist if you are not sure).

If you give more Tiorfan than you should

If your child has taken more Tiorfan than they should, contact your doctor or pharmacist immediately.

If you forget to give Tiorfan

Do not give your child a double dose to make up for a forgotten dose. Simply continue with the treatment.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everyone gets them.

Stop administering Tiorfan to your child and contact a doctor immediately if your child experiences symptoms of angioedema, such as:

  • swelling of the face, tongue, or pharynx
  • difficulty swallowing
  • hives and difficulty breathing

Discontinue the use of racecadotril and seek immediate medical attention if you notice any of the following symptoms:

  • Widespread skin rash, high body temperature, and swollen lymph nodes (DRESS syndrome)
  • Difficulty breathing, swelling, dizziness, rapid heartbeat, sweating, and feeling of loss of consciousness, symptoms of a severe and sudden allergic reaction.

The following side effects have been reported:

Uncommon (may affect up to 1 in 100 people): tonsillitis (inflammation of the tonsils), rash, and erythema (redness of the skin).

Frequency not known (frequency cannot be estimated from available data):

erythema multiforme (red lesions on the extremities and inside the mouth), tongue swelling, facial swelling, lip swelling, eyelid swelling, urticaria, erythema nodosum (inflammation in the form of lumps under the skin), papular rash (rash on the skin with small, hard, and raised lesions), prurigo (lesions on the skin with itching), and pruritus (generalized itching).

Reporting side effects

If you experience any side effects, consult your doctor, pharmacist, or nurse, even if they are possible side effects not listed in this leaflet. You can also report them directly through the Spanish Medicines Agency's website (www.notificaram.es). By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Tiorfan

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiration date stated on the sachet and carton after EXP. The expiration date is the last day of the month indicated.

No special storage conditions are required.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Package contents and additional information

Composition of Tiorfan

The active substance is racecadotril. Each sachet contains 30 mg of racecadotril.

The other ingredients are:

sucrose,

colloidal anhydrous silica,

30% polyacrylate dispersion,

apricot flavor.

Appearance of Tiorfan and package contents

Tiorfan is presented in the form of granules for oral suspension in sachets.

Each pack contains 10, 16, 20, 30, 50, or 100 sachets (100 sachets only as a clinical pack).

Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Marketing authorization holder

BIOPROJET-FERRER, S.L.

Gran Vía Carlos III, 94

08028 Barcelona (Spain)

Manufacturer

FERRER INTERNACIONAL, S.A.

Joan Buscallà 1-9

08173 Sant Cugat del Vallès, Barcelona (Spain)

or

SOPHARTEX,

21 rue de Pressoir,

28500 Vernouillet (France)

This medicine is authorized in the Member States of the European Economic Area under the following names:

GERMANY: Tiorfan

PORTUGAL: Tiorfan

GREECE: Hidrasec

ITALY: Tiorfix

AUSTRIA: Hidrasec

BELGIUM: Tiorfast

CZECH REPUBLIC: Hidrasec

DENMARK: Hidrasec

ESTONIA: Hidrasec

FINLAND: Hidrasec

HUNGARY: Hidrasec

IRELAND: Hidrasec

LATVIA: Hidrasec

LITHUANIA: Hidrasec

LUXEMBOURG: Tiorfast

NETHERLANDS: Tiorfan

POLAND: Hidrasec

SLOVAKIA: Hidrasec

SLOVENIA: Hidrasec

SWEDEN: Hidrasec

UNITED KINGDOM: Hidrasec

Date of the last revision of this leaflet 24-11-2024

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) www.aemps.gob.es.

Alternatives to TIORFAN NIÑOS 30 mg ORAL SUSPENSION GRANULES in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to TIORFAN NIÑOS 30 mg ORAL SUSPENSION GRANULES in Poland

Dosage form: Granulate, 30 mg
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Marketing authorisation holder (MAH): Ferrer Internacional, S.A.
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Dosage form: Capsules, 100 mg
Active substance: racecadotril
Marketing authorisation holder (MAH): Ferrer Internacional, S.A.
Prescription not required

Alternative to TIORFAN NIÑOS 30 mg ORAL SUSPENSION GRANULES in Ukraine

Dosage form: granules, 30 mg
Active substance: racecadotril
Prescription not required
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Online doctors for TIORFAN NIÑOS 30 mg ORAL SUSPENSION GRANULES

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for TIORFAN NIÑOS 30 mg ORAL SUSPENSION GRANULES – subject to medical assessment and local rules.

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Andrei Popov

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Dr. Andrei Popov is a licensed pain management specialist and general practitioner based in Spain. He provides expert online care for adults dealing with both chronic and acute pain, as well as a wide range of everyday health concerns.

He specialises in diagnosing and treating pain conditions that affect quality of life, including:

  • Chronic pain lasting more than 3 months.
  • Migraines and recurring headaches.
  • Neck, back, lower back, and joint pain.
  • Post-traumatic pain following injury or surgery.
  • Nerve-related pain, fibromyalgia, and neuralgia.
In addition to pain management, Dr. Popov helps patients with:
  • Respiratory infections (colds, bronchitis, pneumonia).
  • High blood pressure and metabolic conditions such as diabetes.
  • Preventive care and routine health check-ups.

Online consultations last up to 30 minutes and include a detailed symptom review, personalised treatment planning, and medical follow-up when needed.

Dr. Popov’s approach is rooted in evidence-based medicine, combined with individualised care tailored to each patient’s history, lifestyle, and clinical needs.

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Yevgen Yakovenko

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Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Tomasz Grzelewski

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For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
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  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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Dr. Ben Ami offers expert diagnosis, treatment, and follow-up for:

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  • ENT conditions such as sinusitis, ear infections, and tonsillitis.
  • Digestive issues including gastritis, acid reflux, and irritable bowel syndrome (IBS).
  • Urinary tract infections and other common infections.
  • Management of chronic diseases: high blood pressure, diabetes, thyroid disorders.
  • Acute conditions requiring urgent medical attention.
  • Headaches, migraines, and minor injuries.
  • Wound care, health check-ups, and ongoing prescriptions.

With a patient-focused and evidence-based approach, Dr. Ben Ami supports individuals at all stages of life — offering clear medical guidance, timely interventions, and continuity of care.

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Areas of expertise:

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Dr Kuznetsova helps patients manage cardiovascular risk factors, optimise long-term treatment, and gain clarity in complex health situations – all through accessible and structured online care.
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Dr. Ben Harbi offers reliable, accessible medical support through online consultations, helping patients make informed decisions about their health with a clear, structured, and compassionate approach.

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Cardiology – Diagnosis and treatment of:

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Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
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Gastroenterology – Digestive health:
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General internal medicine and preventive care:
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  • Adult vaccinations – planning, contraindications assessment.
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  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
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  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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