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TIORFAN 100 mg HARD CAPSULES

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use TIORFAN 100 mg HARD CAPSULES

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Tiorfan 100 mg Hard Capsules

racecadotril

Read all of this leaflet carefully before you start taking this medicine.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack:

  1. What is Tiorfan and what is it used for
  2. What you need to know before you take Tiorfan
  3. How to take Tiorfan
  4. Possible side effects
  5. Storage of Tiorfan
  6. Contents of the pack and further information

1. What is Tiorfan and what is it used for

Tiorfan is a medicine for the treatment of diarrhea.

Tiorfan is used to treat the symptoms of acute diarrhea in adults, when the causes of diarrhea cannot be treated.

If causal treatment is possible, racecadotril may be administered as complementary treatment.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Tiorfan

Do not take Tiorfan

  • If you are allergic to racecadotril or any of the other ingredients of Tiorfan (listed in section 6).
  • If you have ever developed a severe skin rash, blistering, or peeling of the skin after taking racecadotril.

Warnings and precautions

Consult your doctor or pharmacist before taking Tiorfan if:

  • there is blood or pus in your stools and if you have a fever. The cause of the diarrhea may be a bacterial infection that needs to be treated by your doctor.
  • you suffer from chronic diarrhea or diarrhea caused by antibiotics.
  • you have kidney disease or insufficient liver function.
  • you have prolonged or uncontrolled vomiting.
  • you have lactose intolerance (see "Important information about some of the ingredients of Tiorfan").

Racecadotril, the active substance of Tiorfan, may cause an allergic reaction called angioedema, which can cause swelling of the face, lips, throat, or tongue. If you experience these side effects, stop treatment immediately and contact your doctor. Swelling can occur at any time during treatment with this product.

Concomitant use of this product and other medicines may increase the risk of angioedema (see "Other medicines and Tiorfan").

Skin reactions have been reported with the use of this product. In most cases, they are mild and do not require treatment. In some cases, severe skin reactions may occur. In these cases, treatment with Tiorfan should be stopped immediately and the patient should not take it again.

Severe skin reactions, including drug reaction with eosinophilia and systemic symptoms (DRESS), have been reported in association with treatment with racecadotril. Stop using racecadotril and seek medical attention immediately if you notice any of the symptoms related to these severe skin reactions described in section 4.

Using Tiorfan with other medicines

Please inform your doctor if you are using, have recently used, or might use any other medicines.

Especially inform your doctor if you are taking any of the following medicines, as they may increase the risk of side effects (see "Warnings and precautions"):

  • ACE inhibitor (e.g., captopril, enalapril, lisinopril, perindopril, ramipril) used to lower blood pressure or treat heart failure.
  • Angiotensin II receptor antagonists (e.g., candesartan or irbesartan) used to treat high blood pressure and heart failure.
  • Sacubitril, used to treat heart failure.
  • Some immunosuppressants (e.g., sirolimus or everolimus).
  • Some antidiabetics (e.g., sitagliptina or vildagliptina).
  • Estramustine, used to treat cancer.
  • Alteplase, used to treat blood clots.

Pregnancy and breastfeeding

Tiorfan is not recommended if you are pregnant or think you may be pregnant, or if you are breastfeeding.

Consult your doctor or pharmacist before taking any medicine.

Driving and using machines

Tiorfan has little or no effect on the ability to drive or use machines.

Tiorfan contains lactose

Tiorfan contains lactose (a type of sugar). If your doctor has told you that you have an intolerance to some sugars, ask your doctor before taking Tiorfan.

This medicine does not contain gluten.

3. How to take Tiorfan

Follow the instructions for administration of this medicine exactly as indicated by your doctor or pharmacist. If you are unsure, consult your doctor or pharmacist again.

The usual dose is one capsule three times a day, which should be swallowed with a glass of water.

Tiorfan is presented in the form of hard capsules.

The usual dose is one capsule three times a day, which should be swallowed with a glass of water. Tiorfan should be taken preferably before main meals, but to start treatment, you can take a Tiorfan capsule at any time of the day.

Your doctor will indicate the duration of treatment with Tiorfan. Treatment should be maintained until two normal stools are produced, not exceeding 7 days.

To compensate for fluid loss due to diarrhea, this medicine should be used along with adequate fluid and electrolyte replacement. The best replacement of fluids and salts is achieved with an oral rehydration solution (please ask your doctor or pharmacist if you are unsure).

No dose adjustment is required in the elderly.

Children

For use in children and infants, other forms of Tiorfan are available.

If you take more Tiorfan than you should

If you take more Tiorfan than you should, please contact your doctor or pharmacist immediately.

If you forget to take Tiorfan

Do not take a double dose to make up for a forgotten dose. Simply continue with the treatment.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Stop taking Tiorfan and contact a doctor immediately if you experience symptoms of angioedema, such as:

  • swelling of the face, tongue, or pharynx
  • difficulty swallowing
  • hives and difficulty breathing

Stop using racecadotril and seek medical attention immediately if you notice any of the following symptoms:

  • Widespread skin rash, high body temperature, and increased lymph nodes (DRESS syndrome)
  • Breathing difficulties, swelling, dizziness, rapid heartbeat, sweating, and feeling of loss of consciousness, symptoms of a severe and sudden allergic reaction.

The following side effects have been reported:

Common (may affect up to 1 in 10 people): headache.

Uncommon (may affect up to 1 in 100 people): rash and erythema (redness of the skin).

Frequency not known (frequency cannot be estimated from the available data): erythema multiforme (red lesions on the extremities and inside the mouth), tongue swelling, facial swelling, lip swelling, eyelid swelling, urticaria, erythema nodosum (inflammation in the form of lumps under the skin), papular rash (rash on the skin with small, hard, and raised lesions), prurigo (lesions on the skin with itching), pruritus (generalized itching), and toxic skin rash.

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Medicines Monitoring System (www.notificaram.es). By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Tiorfan

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date stated on the carton after EXP.

The expiry date is the last day of the month stated.

No special storage conditions are required.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and further information

Composition of Tiorfan

The active substance is racecadotril. Each capsule contains 100 mg of racecadotril.

The other ingredients are lactose, pregelatinized corn starch, magnesium stearate, and anhydrous colloidal silica. The capsule contains gelatin, yellow iron oxide (E 172), and titanium dioxide (E 171).

Appearance of Tiorfan and contents of the pack

Tiorfan is presented in the form of hard ivory-colored capsules.

Each pack contains 6, 10, 20, 100, or 500 hard capsules. The 100 and 500 capsule packs are for hospital use only.

Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Marketing authorization holder

BIOPROJET-FERRER, S.L.

Gran Vía Carlos III, 94

08028 Barcelona (Spain)

Manufacturer

FERRER INTERNACIONAL, S.A.

Joan Buscallà 1-9

08173 Sant Cugat del Vallès, Barcelona (Spain)

or

SOPHARTEX,

21 rue de Pressoir,

28500 Vernouillet (France)

This medicine is authorized in the Member States of the European Economic Area under the following names:

GERMANY: Tiorfan

PORTUGAL: Tiorfan

GREECE: Hidrasec

ITALY: Tiorfix

AUSTRIA: Hidrasec

BELGIUM: Tiorfix

CZECH REPUBLIC: Hidrasec

DENMARK: Hidrasec

ESTONIA: Hidrasec

FINLAND: Hidrasec

HUNGARY: Hidrasec

IRELAND: Hidrasec

LATVIA: Hidrasec

LITHUANIA: Hidrasec

LUXEMBOURG: Tiorfix

NETHERLANDS: Hidrasec

POLAND: Tiorfan

SLOVAKIA: Hidrasec

SLOVENIA: Hidrasec

SWEDEN: Hidrasec

UNITED KINGDOM: Hidrasec

This leaflet was approved on 24-11-2024

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) www.aemps.gob.es.

Online doctors for TIORFAN 100 mg HARD CAPSULES

Discuss questions about TIORFAN 100 mg HARD CAPSULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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€50
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Doctor

Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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€55

Frequently Asked Questions

Is a prescription required for TIORFAN 100 mg HARD CAPSULES?
TIORFAN 100 mg HARD CAPSULES requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in TIORFAN 100 mg HARD CAPSULES?
The active ingredient in TIORFAN 100 mg HARD CAPSULES is racecadotril. This information helps identify medicines with the same composition but different brand names.
Who manufactures TIORFAN 100 mg HARD CAPSULES?
TIORFAN 100 mg HARD CAPSULES is manufactured by Bioprojet Ferrer. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of TIORFAN 100 mg HARD CAPSULES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether TIORFAN 100 mg HARD CAPSULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to TIORFAN 100 mg HARD CAPSULES?
Other medicines with the same active substance (racecadotril) include HIDRASEC 100 mg HARD CAPSULES, TIORFAN INFANTIL 4 mg/mL ORAL SUSPENSION, TIORFAN LACTANTES 10 mg ORAL SUSPENSION GRANULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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