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SIBNAYAL 8 mEq PROLONGED-RELEASE GRANULES

Ask a doctor about a prescription for SIBNAYAL 8 mEq PROLONGED-RELEASE GRANULES

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Doctor

Muhammad Tayyab Altaf

General medicine3 years of experience

Dr. Muhammad Tayyab Altaf is a primary care physician with extensive international experience, offering online consultations for adults and children. His background includes clinical practice in Policlinico San Matteo Hospital Pavia in Italy, Mount Sinai Hospital in New York, United States and other healthcare settings, allowing him to manage a wide range of acute and chronic medical conditions with confidence and clarity.

His clinical expertise spans multi-system conditions, preventive care and long-term management of chronic diseases. Dr. Altaf combines hands-on experience with a strong research background in both medical and surgical fields, enabling him to provide accurate assessments and structured, evidence-based treatment plans. Patients value his ability to explain diagnoses clearly, outline next steps and support them in making informed healthcare decisions.

Online consultations with Dr. Altaf are suitable for many everyday and acute situations where a timely medical opinion can help determine the safest next steps. He evaluates and treats conditions affecting the cardiovascular, respiratory, gastrointestinal, neurological, haematological and endocrine systems. Common examples include:

  • hypertension and other blood pressure issues
  • ischaemic heart disease and angina
  • asthma, COPD and emphysema
  • pneumonia and lung fibrosis
  • gastroenteritis and digestive infections
  • liver conditions, including alcohol-related disease
  • epilepsy, seizures and post-stroke symptoms
  • dementia and cognitive decline
  • anaemia and other haematological changes
  • diabetes, thyroid disorders and pituitary disease
Many patients reach out when they experience new or worsening symptoms, fluctuations in blood pressure, non-severe chest discomfort, breathing symptoms, digestive issues, suspected infections, chronic fatigue or concerns that affect daily life. He also helps patients understand test results, adjust existing treatment plans and navigate long-term health strategies safely and effectively.

When clinically appropriate, Dr. Altaf can also provide health and fitness certificates, including documentation required for physical activity, sports participation or gym use, based on the patient’s health status and medical indications.

Some conditions are not suitable for online care. Severe chest pain, loss of consciousness, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack require immediate attention from local emergency services. Dr. Altaf prioritises patient safety and will guide you accordingly if your situation needs urgent in-person care.

In all consultations, Dr. Muhammad Tayyab Altaf focuses on clear communication, accurate diagnosis and patient-centred decision-making. His approach ensures that individuals and families feel informed, supported and confident in their next steps, no matter where they are.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use SIBNAYAL 8 mEq PROLONGED-RELEASE GRANULES

Introduction

Package Leaflet: Information for the User

Sibnayal 8 mEq prolonged-release granules

Sibnayal 24 mEq prolonged-release granules

potassium citrate/potassium acid carbonate

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Sibnayal and what is it used for
  2. What you need to know before you take Sibnayal
  3. How to take Sibnayal
  4. Possible side effects
  5. Storage of Sibnayal
  6. Contents of the pack and other information

1. What is Sibnayal and what is it used for

Sibnayal contains two active substances, potassium citrate and potassium acid carbonate (also known as potassium bicarbonate).

Sibnayal is an alkalizing medicine used to control blood acidity caused by a kidney disease called distal renal tubular acidosis (dRTA).

Sibnayal will help reduce the effect of dRTA on your daily life.

Sibnayal is used in adults, adolescents, and children over 1 year of age.

2. What you need to know before you take Sibnayal

Do not take Sibnayal

  • if you are allergic to potassium citrate or potassium bicarbonate or any of the other ingredients of this medicine (listed in section 6),
  • if you have severe kidney disease or kidney failure,
  • if you have high potassium levels in your blood (hyperkalemia).

Warnings and precautions

Talk to your doctor before taking Sibnayal

  • if you have a disease or take a medicine that may increase potassium levels in your blood (see section "Other medicines and Sibnayal"),
  • if you frequently have gastrointestinal symptoms such as abdominal distension, diarrhea, nausea, or vomiting,
  • if you have chronic kidney disease.

The prolonged-release granules of Sibnayal are designed to release the active substances slowly after taking the medicine. It is possible to observe remains of the granules in the stool. This is normal and does not reduce the effectiveness of the medicine.

If you vomit within 2 hours of taking the medicine, you should take another dose.

Medical supervision is required when using this medicine.

Your doctor will regularly check your kidney function if you are an elderly person or if your kidney function worsens.

Children

Do not give this medicine to children under 1 year of age because there is a risk of choking.

Other medicines and Sibnayal

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

Some medicines may affect how Sibnayal works or may cause side effects more easily. These include:

  • any medicine that increases potassium levels in the blood, such as:
  • angiotensin-converting enzyme (ACE) inhibitors (used to treat high blood pressure, heart disease, and kidney disease in patients with type 1 diabetes),
  • potassium-sparing diuretics (used to treat high blood pressure, fluid retention in tissues [edema], and heart disease),
  • potassium supplements (used to prevent or treat low potassium levels in the blood),
  • cyclosporin (used to prevent or treat transplant rejection),
  • sodium heparin (used to prevent or delay blood clotting),
  • non-steroidal anti-inflammatory drugs (NSAIDs) (used to reduce fever, pain, and inflammation),
  • any medicine that may be affected by changes in potassium levels in the blood, such as:
  • digitalis glycosides (such as digoxin, used to treat heart failure and certain heart rhythm disorders),
  • corticosteroids (used to treat inflammation),
  • any other medicine that may cause heart rhythm disorders, such as:
  • amiodarone and quinidine (used to control heart rhythm),
  • chlorpromazine (used to treat certain mental illnesses),
  • cisapride (used to treat heartburn),
  • esparfloxacine (used to treat certain bacterial infections).

Some medicines may be affected by the increased pH of the urine related to Sibnayal treatment, such as:

  • salicylates (used to treat pain and inflammation, medicines similar to aspirin),
  • tetracyclines (used to treat certain bacterial infections),
  • barbiturates (sleeping medicines).

Using Sibnayal with food, drinks, and alcohol

Do not mix Sibnayal with food or hot liquids.

Do not consume alcohol during treatment with Sibnayal.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Driving and using machines

Sibnayal is unlikely to affect your ability to drive or use machines.

Sibnayal contains potassium

Sibnayal 8 mEq contains 308 mg of potassium per sachet. This should be taken into account if you have kidney failure or are on a potassium-controlled diet.

Sibnayal 24 mEq contains 924 mg of potassium per sachet. This should be taken into account if you have kidney failure or are on a potassium-controlled diet.

3. How to take Sibnayal

Take this medicine exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist.

The amount of Sibnayal you should take will depend on your age, weight, and condition. Your doctor will prescribe the exact dose of Sibnayal you should take. It will always be one or more whole sachets of medicine.

Your doctor may need to adjust your dose of Sibnayal.

This medicine requires medical supervision.

Dosage

Your doctor will adjust the dose based on the levels of bicarbonate in your blood.

How to use Sibnayal

Sibnayal should be taken orally (by mouth).

If you are not sure how to use Sibnayal, ask your doctor or pharmacist.

  1. Hold the sachet vertically and hold it with your fingers above the dashed line. Shake it well from side to side to make sure all the contents are moved to the bottom of the sachet.

Hand turning the plunger of a pre-filled syringe with a curved arrow indicating the direction of rotation

  1. Cut the sachet along the dashed line, using scissors if necessary.

Hand holding a dark patch being cut with silver-plated scissors, black arrow indicates cut number two in the lower left corner

  1. Put all or part of the sachet contents directly into your mouth over your tongue.

Person applying a buccal inhaler with mouth open and hands holding the device

  1. Swallow the granules immediately with a large glass of water. Do not chew or crush the granules. Repeat steps 1 to 4, as necessary, until you have taken the complete dose.

Person applying a buccal inhaler with one hand holding the device and the other covering the mouth

For patients who cannot swallow the granules

  1. Mix Sibnayal with a small amount of soft, cold food (such as fruit puree or yogurt) directly in the spoon. Swallow the mixture of medicine and soft food immediately. Do not keep the mixture for later use.

Hands holding a spoon with white powder and a vial with dark liquid being prepared to mix

  1. Put the mixture directly into your mouth and swallow it without chewing. Make sure there are no remaining Sibnayal granules in your mouth. Repeat steps 1 and 2, as necessary, until you have taken the complete dose.

Person opening their mouth while a hand offers a spoonful of liquid medicine

Do not mix the granules with liquid before taking them.

When to take Sibnayal

Sibnayal should be taken in the morning and at night, during a meal. You should leave an interval of about 12 hours between the two doses to cover the day and night.

Shining sun and crescent moon with two clocks indicating time intervals of more than 12 hours

Dose adjustments

The dose will be gradually increased or decreased over several weeks. Your doctor will adjust the dose based on your condition. The recommended dose is usually 4 to 6 complete sachets of 24 mEq per day.

If you notice any side effects, talk to your doctor, as it may be necessary to adjust the dose of this medicine.

Switching from another alkalizing medicine to Sibnayal

When switching from another alkalizing medicine to Sibnayal, your doctor should closely monitor the transition.

If you take more Sibnayal than you should

Talk to your doctor or pharmacist if you have taken more Sibnayal than you should.

You may feel nauseous, need to vomit, and have diarrhea.

If you have taken a large amount of Sibnayal, you may feel weak or have unexplained muscle stiffness, spasms (muscle contraction), abnormal tingling or burning sensation, numbness or insensitivity, mental confusion, or abnormal heart rate.

If you forget to take Sibnayal

Do not take a double dose to make up for a forgotten dose. Take it as soon as you remember. However, if it is less than 6 hours until the next dose, skip the missed dose. Do not take more than two doses per day.

Talk to your doctor if you have forgotten to take one or more doses.

If you stop taking Sibnayal

This medicine is for long-term treatment. It will only be effective if you take it.

Do not stop treatment unless your doctor tells you to, even if you feel better, as your disease may worsen. If you want to stop treatment, talk to your doctor first.

If you have any further questions on the use of this medicine, ask your doctor.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Very common side effects(may affect more than 1 in 10 people)

  • abdominal pain (stomach pain)

Common side effects(may affect up to 1 in 10 people)

  • upper abdominal pain (pain in the upper part of the stomach)
  • abdominal and gastrointestinal disorders (abdominal and intestinal disorders),
  • dyspepsia (indigestion),
  • vomiting,
  • diarrhea,
  • nausea when starting treatment.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system listed in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Sibnayal

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the sachet and the carton after EXP. The expiry date is the last day of the month shown.

Do not store above 30°C.

After opening a sachet, discard the unused contents.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

What is in Sibnayal

The active substances are potassium citrate and potassium acid carbonate (also known as potassium bicarbonate).

Each Sibnayal 8 mEq sachet contains 282 mg of potassium citrate and 527 mg of potassium acid carbonate.

Each Sibnayal 24 mEq sachet contains 847 mg of potassium citrate and 1582 mg of potassium acid carbonate.

The other ingredients are hypromellose (E464), microcrystalline cellulose (E460 (i)), glycerol dibehenate, magnesium stearate (E470b), colloidal anhydrous silica, heavy magnesium oxide (E530), ethylcellulose (E462), chlorophyllin (E140 (ii)), and talc.

Appearance and packaging

Sibnayal is a mixture of prolonged-release granules of green and white color, which are supplied in sachets.

The cartons contain 60 sachets.

Sibnayal is supplied in multiple packs containing 2, 3, 4, 5, and 6 cartons, each containing 60 sachets.

Not all pack sizes may be marketed.

Marketing authorization holder

ADVICENNE

262 rue du Faubourg Saint Honoré

75008 Paris

France

[email protected]

You can request more information about this medicine from the local representative of the marketing authorization holder:

Denmark - Norway - Sweden

Frostpharma AB

Berga Backe 2

18253 Danderyd, Sweden

Tel: + 46 8 243660

[email protected]

Finland

Frostpharma AB

Berga Backe 2

18253 Danderyd, Sweden

Tel: + 35 875 32 51 209

[email protected]

Belgium - Belgium - Germany - Estonia - Greece - Spain - France - Croatia - Ireland - Iceland - Italy - Cyprus - Latvia - Lithuania - Luxembourg - Hungary - Malta - Netherlands - Austria - Poland - Portugal - Romania - Slovenia - Slovakia - United Kingdom (Northern Ireland)

ADVICENNE

262 rue du Faubourg Saint Honoré

75008 Paris, France

Tel : + 33 1 85 73 36 21

Manufacturer

ELAIAPHARM

2881 route des Crêtes

ZI les Bouillides Sophia Antipolis

06560 Valbonne

France

Date of last revision of this leaflet

Other sources of information

Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu.

Online doctors for SIBNAYAL 8 mEq PROLONGED-RELEASE GRANULES

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for SIBNAYAL 8 mEq PROLONGED-RELEASE GRANULES – subject to medical assessment and local rules.

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Key areas of consultation:

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She has conducted research on the genetic background of stroke and is skilled in communicating with patients from diverse cultural backgrounds. Her approach combines clinical expertise with empathy and clear communication.
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His clinical expertise spans multi-system conditions, preventive care and long-term management of chronic diseases. Dr. Altaf combines hands-on experience with a strong research background in both medical and surgical fields, enabling him to provide accurate assessments and structured, evidence-based treatment plans. Patients value his ability to explain diagnoses clearly, outline next steps and support them in making informed healthcare decisions.

Online consultations with Dr. Altaf are suitable for many everyday and acute situations where a timely medical opinion can help determine the safest next steps. He evaluates and treats conditions affecting the cardiovascular, respiratory, gastrointestinal, neurological, haematological and endocrine systems. Common examples include:

  • hypertension and other blood pressure issues
  • ischaemic heart disease and angina
  • asthma, COPD and emphysema
  • pneumonia and lung fibrosis
  • gastroenteritis and digestive infections
  • liver conditions, including alcohol-related disease
  • epilepsy, seizures and post-stroke symptoms
  • dementia and cognitive decline
  • anaemia and other haematological changes
  • diabetes, thyroid disorders and pituitary disease
Many patients reach out when they experience new or worsening symptoms, fluctuations in blood pressure, non-severe chest discomfort, breathing symptoms, digestive issues, suspected infections, chronic fatigue or concerns that affect daily life. He also helps patients understand test results, adjust existing treatment plans and navigate long-term health strategies safely and effectively.

When clinically appropriate, Dr. Altaf can also provide health and fitness certificates, including documentation required for physical activity, sports participation or gym use, based on the patient’s health status and medical indications.

Some conditions are not suitable for online care. Severe chest pain, loss of consciousness, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack require immediate attention from local emergency services. Dr. Altaf prioritises patient safety and will guide you accordingly if your situation needs urgent in-person care.

In all consultations, Dr. Muhammad Tayyab Altaf focuses on clear communication, accurate diagnosis and patient-centred decision-making. His approach ensures that individuals and families feel informed, supported and confident in their next steps, no matter where they are.

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  • Hypertension control and cardiovascular disease prevention
  • Interpretation of ECG, blood tests, and Holter monitor results
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  • General medical issues: infections, fever, fatigue, gastrointestinal symptoms
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Dr. Alhasan’s approach is based on thorough assessment, clear communication, and personalised care – helping patients understand their health and make informed decisions about their treatment.
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Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

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Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
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He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Dr Reznychenko offers a clear, attentive and professional approach. Her consultations help prevent minor discomforts from developing into more serious concerns – all in a convenient online format.
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  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
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Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
  • chest discomfort, palpitations, dizziness, fatigue, and blood pressure concerns;
  • digestive problems: abdominal pain, nausea, diarrhoea, constipation, reflux;
  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders;
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