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RUPAFIN 1 mg/ml ORAL SOLUTION

RUPAFIN 1 mg/ml ORAL SOLUTION

Ask a doctor about a prescription for RUPAFIN 1 mg/ml ORAL SOLUTION

5.0(2)
Doctor

Tomasz Grzelewski

Dermatology21 years of experience

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use RUPAFIN 1 mg/ml ORAL SOLUTION

Introduction

Patient Information Leaflet

Rupafin 1 mg/ml oral solution

Rupatadine

Read this leaflet carefully before starting to take this medicine, as it contains important information for you.

  • Keep this leaflet, as you may need to read it again.
  • If you have any questions, ask your doctor or pharmacist.
  • This medicine has been prescribed to you only, and you should not give it to others, even if they have the same symptoms as you, as it may harm them.
  • If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.

Contents of the leaflet

  1. What is Rupafin and what is it used for
  2. What you need to know before taking Rupafin
  3. How to take Rupafin
  4. Possible side effects
  5. Storage of Rupafin
  6. Package contents and additional information

1. What is Rupafin and what is it used for

Rupafin contains the active ingredient rupatadine, which is an antihistamine.

Rupafin oral solution is indicated for the relief of symptoms of allergic rhinitis such as sneezing, nasal discharge, nasal congestion, itching of the nose and eyes in children from 2 to 11 years old.

Rupafin is also indicated for the relief of symptoms associated with urticaria (allergic skin rash) such as itching and skin wheals (redness and swelling of the skin) in children from 2 to 11 years old.

2. What you need to know before taking Rupafin

Do not take Rupafin:

  • If you are allergic to rupatadine or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Consult your doctor or pharmacist before starting to take Rupafin.

If you have kidney or liver failure, consult your doctor. The use of Rupafin is not currently recommended in patients with kidney or liver failure.

If you have low potassium levels in your blood and/or if you have a certain abnormal heart rhythm (known QTc interval prolongation on the ECG) that may occur in certain heart diseases, consult your doctor.

Children

This medicine should not be used in children under 2 years old or weighing less than 10 kg.

Other medicines and Rupafin

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

If you are taking Rupafin, do not take medicines that contain ketoconazole (a medicine for fungal infections) or erythromycin (a medicine for bacterial infections).

If you are taking medicines that depress the central nervous system, statins (medicines used to treat high cholesterol levels) or midazolam (a medicine used for short-term sedation), consult your doctor before taking Rupafin.

Taking Rupafin with food, drinks, and alcohol

Rupafin can be taken with or without food.

Do not take Rupafin in combination with grapefruit juice, as it may increase the level of rupatadine in your body.

Rupafin at a dose of 10 mg does not increase the drowsiness produced by alcohol.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Driving and using machines

It is unlikely that Rupafin will affect your ability to drive or use machines at the recommended dose. However, when you first use Rupafin, you should be cautious and see how the treatment affects you before driving or using machines.

Rupafin contains sucrose, methyl parahydroxybenzoate, and propylene glycol.

If your doctor has told you that you have an intolerance to certain sugars, consult your doctor before taking this medicine. It may cause tooth decay.

It may cause allergic reactions (possibly delayed) because it contains methyl parahydroxybenzoate.

This medicine contains 200 mg of propylene glycol in each ml.

If your child is under 5 years old, talk to your doctor or pharmacist before giving them this medicine, especially if they use other medicines that contain propylene glycol or alcohol.

If you are pregnant or breastfeeding, do not take this medicine unless your doctor recommends it. Your doctor may perform additional checks while you are taking this medicine.

If you have liver or kidney disease, do not take this medicine unless your doctor recommends it. Your doctor may perform additional checks while you are taking this medicine.

This medicine contains less than 23 mg of sodium (1 mmol) per ml, which is essentially "sodium-free".

3. How to take Rupafin

Follow the instructions for administration of this medicine exactly as indicated by your doctor. If you are unsure, consult your doctor or pharmacist again.

Rupafin oral solution is administered orally.

Dosing in children with a weight of 25 kg or more: 5 ml (5 mg of rupatadine) of oral solution once a day, administered with or without food.

Dosing in children with a weight of 10 kg to less than 25 kg: 2.5 ml (2.5 mg of rupatadine) of oral solution once a day, administered with or without food.

Your doctor will indicate the duration of your treatment with Rupafin.

Instructions for use

  • To open the bottle, press the cap and turn it counterclockwise.
  • Insert the syringe into the hole in the cap and turn the bottle upside down.
  • Fill the syringe with the prescribed dose.
  • Administer directly with the dosing syringe.
  • Wash the syringe after each use.

If you take more Rupafin than you should

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 915 620 420, indicating the medicine and the amount ingested.

If you forget to take Rupafin

Do not take a double dose to make up for forgotten doses.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everyone gets them.

Common side effects (may affect up to 1 in 10 patients) are headache and drowsiness.

Uncommon side effects (may affect up to 1 in 100 patients) are flu, nasopharyngitis, upper respiratory tract infections, increased eosinophils, decreased neutrophils, dizziness, nausea, eczema, night sweats, and fatigue.

Reporting side effects:

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Rupafin

Keep this medicine out of the sight and reach of children.

This medicine does not require special storage conditions.

Do not use this medicine after the expiry date stated on the carton and bottle after EXP. The expiry date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Dispose of the packaging and any unused medicine in the SIGRE collection point at your pharmacy. If you are unsure, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Package contents and additional information

Composition of Rupafin

  • The active ingredient is rupatadine. Each ml contains 1 mg of rupatadine (as fumarate).
  • The other ingredients are: propylene glycol (E-1520), anhydrous citric acid, anhydrous disodium phosphate, sodium saccharin, sucrose, methyl parahydroxybenzoate (E-218), quinoline yellow (E-104), banana flavor, and purified water. See section 2 "Rupafin contains sucrose, methyl parahydroxybenzoate, and propylene glycol".

Appearance and packaging of the product:

Rupafin is a clear yellow solution.

Rupafin is available in topaz plastic bottles with a built-in perforated stopper and child-resistant cap. Each pack contains a bottle with 120 ml of oral solution and includes a 5 ml oral syringe graduated to 0.25 ml.

Marketing authorization holder

LABORATORIOS ERN, S.A.

Perú, 228

08020 Barcelona

Spain

Manufacturer

Italfarmaco, S.A.

San Rafael, 3

Pol. Ind. Alcobendas

E-28108 Alcobendas (Spain)

or

NOUCOR HEALTH, S.A.

Av. Camí Reial 51-57

08184 Palau-solità i Plegamans (Barcelona-Spain)

This medicine is authorized in the Member States of the European Economic Area under the following names:

Rupatall 1 mg/ml oral solution Belgium, Luxembourg

Rinialer 1 mg/ml oral solution Portugal, Malta

Rupafin 1mg/ml oral solution Austria, Bulgaria, Croatia, Cyprus, Denmark, Estonia, Germany, Greece, Iceland, Italy, Ireland, Latvia, Liechtenstein, Lithuania, Netherlands, Norway, Poland, Slovenia, Slovakia, Spain

Rupatadine 1 mg/ml oral solution United Kingdom

Wystamm 1mg/ml oral solution France

Tamalis 1mg/ml oral solution Hungary, Czech Republic, Romania

Pafinur 1mg/ml oral solution Finland, Sweden

Date of last revision of this leaflet: 08/2020

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es

About the medicine

How much does RUPAFIN 1 mg/ml ORAL SOLUTION cost in Spain ( 2026)?

The average price of RUPAFIN 1 mg/ml ORAL SOLUTION in January, 2026 is around 7.12 EUR. Prices may vary depending on the region, pharmacy, and whether a prescription is required. Always check with a local pharmacy or online source for the most accurate information.

Alternatives to RUPAFIN 1 mg/ml ORAL SOLUTION in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to RUPAFIN 1 mg/ml ORAL SOLUTION in Польша

Dosage form: Таблетки, 10 мг
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Prescription required
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Marketing authorisation holder (MAH): Noucor Health S.A.
Prescription required
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Active substance: рупатадин
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Marketing authorisation holder (MAH): GALENICA A.E
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Alternative to RUPAFIN 1 mg/ml ORAL SOLUTION in Украина

Dosage form: таблетки, таблетки 10 мг
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Prescription required
Dosage form: раствор, 1 мг/мл; 120 мл во флаконе
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Manufacturer: Italfarmako, S.A.
Prescription required
Dosage form: таблетки, таблетки 10 мг
Active substance: рупатадин
Prescription required
Dosage form: раствор, 1 мг/мл, 100 мл во флаконе
Active substance: рупатадин
Manufacturer: AT "Farmak
Prescription required

Online doctors for RUPAFIN 1 mg/ml ORAL SOLUTION

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for RUPAFIN 1 mg/ml ORAL SOLUTION – subject to medical assessment and local rules.

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Dr Kovalenko combines evidence-based practice with a respectful, patient-centred approach. She takes time to explain, listens attentively, and helps each person make confident, informed decisions about their health.

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Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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Her approach is never one-size-fits-all – each consultation begins with a deep dive into your unique health history, test results, and emotional landscape. Consultations are available in Ukrainian, Polish, and Russian.
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Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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