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MINURIN FLAS 120 micrograms ORAL LYOPHILIZED

Ask a doctor about a prescription for MINURIN FLAS 120 micrograms ORAL LYOPHILIZED

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Doctor

Nuno Tavares Lopes

Family medicine17 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use MINURIN FLAS 120 micrograms ORAL LYOPHILIZED

Introduction

Patient Information Leaflet

Minurin Flas 120 micrograms oral lyophilisate

Desmopressin

Read this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack:

  1. What Minurin Flas is and what it is used for
  2. What you need to know before you take Minurin Flas
  3. How to take Minurin Flas
  4. Possible side effects
  5. Storage of Minurin Flas
  6. Contents of the pack and further information

1. What Minurin Flas is and what it is used for

Minurin Flas contains desmopressin, a structural analogue of the natural antidiuretic hormone arginine vasopressin. Desmopressin belongs to the group of antidiuretic hormone (vasopressin) analogues, which temporarily reduces the amount of urine produced by the body.

Minurin Flas is used to treat central diabetes insipidus (continuous thirst and production of very diluted urine) and primary nocturnal enuresis (bedwetting at night) in patients over 5 years of age with normal urine concentration capacity.

2. What you need to know before you take Minurin Flas

Do not take Minurin Flas:

  • if you are allergic to the active substance or any of the other ingredients of this medicine (listed in section 6).
  • if you have habitual or psychogenic polydipsia (excessive thirst).
  • if you have heart failure or other conditions that require treatment with diuretics (medicines that increase urine production).
  • if you have renal failure.
  • if you have known hyponatremia (low sodium levels in the blood).
  • if you have syndrome of inappropriate antidiuretic hormone secretion (SIADH).

Warnings and precautions

Talk to your doctor or pharmacist before taking Minurin Flas.

  • If you have primary nocturnal enuresis, be careful to restrict fluid intake, not drinking between 1 hour before administration and up to 8 hours after.

Treatment without simultaneous reduction of water intake may cause water retention and/or decreased sodium levels in the blood, accompanied by symptoms and signs of alarm (headache, nausea and vomiting, weight gain, and in severe cases, convulsions). See section 4.

Special care should be taken to avoid decreased sodium levelsin the following cases:

  • Generalized infections, fever, and gastroenteritis(inappropriate antidiuretic hormone secretion).
  • Risk of increased intracranial pressure.
  • Imbalance in water and mineral content.
  • Treatmentwith medications that may cause diabetes insipidus, such as tricyclic antidepressants (e.g., amitriptyline), selective serotonin reuptake inhibitors (e.g., fluoxetine), chlorpromazine, and carbamazepine.
  • Treatmentwith non-steroidal anti-inflammatory drugs (NSAIDs), such as acetylsalicylic acid.

Using other medicines with Minurin Flas

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

Minurin Flas may interact with medicines that can cause diabetes insipidus, such as tricyclic antidepressants (e.g., amitriptyline), selective serotonin reuptake inhibitors (e.g., fluoxetine), chlorpromazine, and carbamazepine, as well as some antidiabetic medicines of the sulfonylurea group, especially chlorpropamide.

Non-steroidal anti-inflammatory drugs may induce water retention and decreased sodium levels in the blood.

Be cautious if you are being treated with loperamide (a medicine used to treat diarrhea), as it may increase the risk of water retention and decreased sodium levels in the blood.

Using Minurin Flas with drinks

Do not drink fluids with Minurin Flas.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

There are no sufficient clinical data to support its use during pregnancy. Animal studies have not shown any fetal risk with the administration of desmopressin.

Desmopressin, although in small amounts, passes into breast milk, so if you are breastfeeding, it is recommended to substitute breastfeeding.

Driving and using machines

Minurin Flas does not affect the ability to drive or use machines.

3. How to take Minurin Flas

Follow the administration instructions of this medicine exactly as indicated by your doctor. If you are unsure, consult your doctor or pharmacist again.

Usual dose

Central diabetes insipidus: Your doctor will adjust the dose individually.

The recommended initial dose for children and adults is 60 micrograms three times a day, administered sublingually (under the tongue). Your doctor will then adjust the dose according to each patient's response.

For most patients, the maintenance dose is 60 to 120 micrograms of desmopressin three times a day.

Primary nocturnal enuresis: The recommended initial dose is 120 micrograms of desmopressin, administered sublingually (under the tongue) at bedtime. If the desired effect is not achieved with this dose, your doctor may increase the dose up to 240 micrograms.

It is essential to control fluid intake (see section 2).

Remember to take your medicine. Your doctor will indicate the duration of your treatment with this medicine.

If you observe symptoms or signs of water retention and/or decreased sodium levels in the blood (headache, nausea, and vomiting, weight gain, and in severe cases, convulsions), you should interrupt treatment until the patient has recovered. Once treatment is restarted, fluid intake will be strictly controlled.

Instructions for use and handling

Place the lyophilisate under the tongue. The lyophilisate dissolves almost instantly in the mouth without the need for fluids. The oral lyophilisate should be taken preferably with food. If you are taking Minurin Flas for primary nocturnal enuresis, it is recommended to take the lyophilisate at bedtime with dinner, once a day.

Instructions for opening a blister pack with arrows indicating where to pull to open the medicine pack

If you think the effect of Minurin Flas is too strong or too weak, tell your doctor or pharmacist.

Duration of treatment

Your doctor will indicate the duration of your treatment with Minurin Flas. Do not stop treatment before completing it, as it may not have the desired effect.

Treatment for primary nocturnal enuresis will last for 3 months. Then, your doctor will assess the need to continue treatment, and if so, it will be restarted after at least a week of rest.

If you take more Minurin Flas than you should

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone (91) 562 04 20, indicating the medicine and the amount taken. It is recommended to take the packaging and leaflet to the healthcare professional.

An overdose may prolong the effect of desmopressin and increase the risk of water retention in the body and/or low sodium levels in the blood. Symptoms may include headache, nausea, and vomiting, weight gain, and in severe cases, convulsions. It is recommended to interrupt treatment, restrict fluid intake, and provide symptomatic treatment if necessary.

If you forget to take Minurin Flas

Do not take a double dose to make up for forgotten doses.

If you stop taking Minurin Flas

Do not stop treatment with this medicine before completing it, as it may not have the desired effect. Only change or stop treatment if your doctor tells you to.

If you have any further questions about the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Frequent, (may affect up to 1 in 10 patients):Headache.

Uncommon, (may affect up to 1 in 100 patients):Mood changes, aggression, abdominal pain, nausea, vomiting, diarrhea, symptoms in the bladder and urethra, peripheral edema, fatigue.

Rare, (may affect up to 1 in 1,000 patients):Anxiety symptoms, nightmares, mood changes, somnolence, hypertension, irritability.

Frequency not known: Anaphylactic reaction, hyponatremia, dehydration, hypernatremia, abnormal behavior, emotional disorder, depression, hallucinations, insomnia, attention disorder, psychomotor hyperactivity, convulsions, asthenia, coma, epistaxis, allergic dermatitis, exanthema, sweating, urticaria.

Due to decreased sodium levels in the blood caused by water retention as a result of treatment, along with reduced fluid intake, headache, nausea, vomiting, decreased sodium levels, weight gain, and in severe cases, convulsions may occur.

Reporting of side effects:

If you experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: http://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Minurin Flas

Keep this medicine out of the sight and reach of children.

This medicine does not require any special storage temperature.

Keep it in the original packaging to protect it from light and moisture.

Do not use this medicine after the expiry date stated on the packaging, after EXP. The expiry date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Return the packaging and any unused medicine to a pharmacy. If you are unsure, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Contents of the pack and further information

Composition of Minurin Flas

  • The active substance is desmopressin acetate. Each oral lyophilisate contains 135 micrograms of desmopressin acetate, equivalent to 120 micrograms of desmopressin.

The other ingredients are: Gelatin, mannitol, and anhydrous citric acid.

Appearance of the product and packaging

The oral lyophilisate is white, round, with a droplet shape on one side.

It is available in aluminum/aluminum blisters of 10 oral lyophilisates.

The packaging contains 10, 30, or 100 oral lyophilisates.

Not all pack sizes may be marketed.

Marketing Authorization Holder and Manufacturer

Marketing Authorization Holder

Ferring S.A.U.

C/ del Arquitecto Sánchez Arcas nº3, 1º

28040 Madrid

  • Spain

Manufacturer

FERRING GmbH

Wittland 11,

D-24109 Kiel

GERMANY

Date of last revision of this leaflet: May 2019

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS)

http://www.aemps.gob.es/

About the medicine

How much does MINURIN FLAS 120 micrograms ORAL LYOPHILIZED cost in Spain ( 2025)?

The average price of MINURIN FLAS 120 micrograms ORAL LYOPHILIZED in December, 2025 is around 34.16 EUR. Prices may vary depending on the region, pharmacy, and whether a prescription is required. Always check with a local pharmacy or online source for the most accurate information.

Alternatives to MINURIN FLAS 120 micrograms ORAL LYOPHILIZED in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to MINURIN FLAS 120 micrograms ORAL LYOPHILIZED in Poland

Dosage form: Tablets, 240 mcg
Active substance: desmopressin
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Prescription required
Dosage form: Tablets, 120 mcg
Active substance: desmopressin
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Dosage form: Tablets, 60 mcg
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Dosage form: Tablets, 120 mcg
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Dosage form: Tablets, 60 mcg
Active substance: desmopressin
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Alternative to MINURIN FLAS 120 micrograms ORAL LYOPHILIZED in Ukraine

Dosage form: solution, 15 mcg/ml; 1 ml in ampoule
Active substance: desmopressin
Manufacturer: Ferring GmbH
Prescription required
Dosage form: lyophilisate, 60 mcg
Active substance: desmopressin
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Dosage form: lyophilisate, 240 mcg
Active substance: desmopressin
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Dosage form: lyophilisate, 120 mcg
Active substance: desmopressin
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Dosage form: tablets, 0.2 mg
Active substance: desmopressin
Prescription required
Dosage form: tablets, 0.1 mg
Active substance: desmopressin
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Online doctors for MINURIN FLAS 120 micrograms ORAL LYOPHILIZED

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for MINURIN FLAS 120 micrograms ORAL LYOPHILIZED – subject to medical assessment and local rules.

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Her areas of focus include:

  • Fever, infections, cough, sore throat, and digestive issues.
  • Preventive care – vaccinations, regular check-ups, and health monitoring.
  • Allergies, asthma, and skin conditions.
  • Nutritional advice and healthy development support.
  • Sleep difficulties, fatigue, and behavioural concerns.
  • Ongoing care for chronic or complex health conditions.
  • Guidance for parents and follow-up after medical treatment.

Dr Akhvlediani combines professional care with a warm, attentive approach – helping children stay healthy and supporting parents at every stage of their child’s growth.

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  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

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  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate
Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.

She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.

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Dr. Meneses graduated from the University of Beira Interior and has years of experience working with diverse patient populations. He is fluent in Portuguese, English, Spanish, and French.

His approach is friendly, clear, and focused on delivering practical medical advice tailored to each patient’s needs.

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If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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