LOARGYS 5 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION

Ask a doctor about a prescription for LOARGYS 5 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION

5.0(40)

Yevgen Yakovenko

General surgery11 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

12+ years of clinical experience in university hospitals in Germany and Spain.
International education: Ukraine – Germany – Spain.
Member of the German Society of Surgeons (BDC).
Certified in radiological diagnostics and robotic surgery.
Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment

Antonio Cayatte

General medicine43 years of experience

Dr Antonio Cayatte is a physician in General and Acute Medicine with over 30 years of experience across clinical care, medical research, and education. He offers online consultations for adults with a wide range of symptoms, both acute and chronic.

His clinical background includes:

assessment of sudden or unclear symptoms
ongoing care for chronic conditions
follow-up after hospital discharge
interpretation of test results
medical support while abroad

Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association.

Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

Book a video appointment

Yevgen Yakovenko

General surgery11 years of experience

Areas of medical expertise:

Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

12+ years of clinical experience in university hospitals in Germany and Spain.
International education: Ukraine – Germany – Spain.
Member of the German Society of Surgeons (BDC).
Certified in radiological diagnostics and robotic surgery.
Active participant in international medical conferences and research.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment

Antonio Cayatte

General medicine43 years of experience

His clinical background includes:

assessment of sudden or unclear symptoms
ongoing care for chronic conditions
follow-up after hospital discharge
interpretation of test results
medical support while abroad

Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

Book a video appointment

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.

How to use LOARGYS 5 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION

Introduction

Package Leaflet: Information for the Patient

Loargys 5 mg/ml Solution for Injection and Infusion

pegzilarginasa

This medicinal product is subject to additional monitoring, which will allow for quick identification of new safety information. You can help by reporting any side effects you may get. The last section of the leaflet includes information on how to report side effects.

Read all of this leaflet carefully before you start taking this medicine, because it contains important information for you.

Keep this leaflet, you may need to read it again.
If you have any further questions, ask your doctor or nurse.
If you experience any side effects, talk to your doctor or nurse, even if they are not listed in this leaflet. See section 4.

Contents of the pack

What is Loargys and what is it used for
What you need to know before you take Loargys
How to take Loargys
Possible side effects
Storage of Loargys
Contents of the pack and further information
Instructions for use

1. What is Loargys and what is it used for

Loargys contains the active substance pegzilarginasa, which is a modified human enzyme produced by recombinant DNA technology. The medicine is used to treat arginase 1 deficiency (ARG1-D), also known as hyperargininemia, in adults, adolescents, and children from 2 years of age.

Patients with ARG1-D have low levels of an enzyme called arginase. This enzyme helps the body control arginine levels, an amino acid that the body needs to produce proteins. If arginine is not controlled, it can accumulate in the body and cause symptoms, such as problems with muscle control.

Loargys is used in combination with other forms of treating the disease. These may include:

a low-protein diet
dietary supplements with essential amino acids
medications to treat other symptoms of the disease, such as medications that reduce ammonia levels in the body.

How Loargys works

The pegzilarginasa, the active substance of Loargys, works in a similar way to the natural enzyme arginase, which is lacking or not functioning properly in patients with ARG1-D. This reduces arginine levels in the blood, thereby reducing the symptoms of the disease.

2. What you need to know before you take Loargys

Do not take Loargys

if you have had a severe allergic reaction to pegzilarginasa or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Loargys may cause allergic reactions. This is more likely to happen after the first few doses.

Stop the injection immediately and contact your doctor or the emergency services if you experience any of the following symptoms of a severe allergic reaction: hives, itching all over, chest tightness, difficulty breathing, or low blood pressure. Your doctor may decide that you need additional medical treatment to prevent or treat an allergic reaction.

During your treatment, your doctor will perform blood tests to check what dose of Loargys is suitable for you.

Children and adolescents

The medicine must not be used in children under 2 years of age, as it is not known if Loargys is safe and effective in this age group.

Using Loargys with other medicines

Tell your doctor if you are taking, have recently taken, or might take any other medicines.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before using this medicine. The use of Loargys is not recommended if you are pregnant.

It is not known if the medicine passes into breast milk. If you are breastfeeding, consult your doctor before taking this medicine. Your doctor will help you decide whether to stop breastfeeding or stop the treatment.

Driving and using machines

Loargys has no or negligible influence on the ability to drive and use machines.

Loargys contains sodium and potassium

This medicine contains less than 1 mmol of sodium (23 mg) per dose; this is essentially "sodium-free". This medicine contains potassium, less than 1 mmol (39 mg) per dose, i.e., essentially "potassium-free".

3. How to take Loargys

Loargys will be administered by a healthcare professional. Your doctor will decide the amount of Loargys you will be given.

The recommended initial dose of Loargys is 0.1 mg per kilogram of body weight, administered once a week. Your doctor may increase or decrease the dose to keep arginine levels in the blood under control. Your doctor will prescribe regular blood tests to check your arginine levels in the blood and change your dose if necessary.

Loargys is administered by infusion (drip) directly into a vein or by subcutaneous injection, as considered appropriate by your doctor.

Your doctor may decide that you can be given Loargys at home, in the form of a subcutaneous injection. After receiving training from your doctor or nurse, you may inject Loargys yourself (see instructions in section 7).

Always use this medicine exactly as described in this leaflet or as directed by your doctor, pharmacist, or nurse. If you are unsure, consult your doctor, pharmacist, or nurse.

If you are given more Loargys than you should

Your doctor will make sure that you are given the correct amount of Loargys. If you are given too much Loargys, your arginine level in the blood may become too low. Symptoms may include nausea, vomiting, diarrhea, and fatigue. If you or your doctor suspect that you have been given too much Loargys, you should be closely monitored and receive the necessary treatment.

If you forget to use Loargys

If you have missed a dose of Loargys, contact your doctor to schedule the next dose as soon as possible. You should not be given a double dose to make up for missed doses, and at least 4 days should pass between doses.

If you stop taking Loargys

Your doctor will decide if you should stop taking Loargys. If you stop taking Loargys, it is likely that your arginine level in the blood will increase again.

If you have any other questions about the use of this medicine, ask your doctor or nurse.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Very common(may affect more than 1 in 10 people)

Injection site reaction. Symptoms may include pain, swelling, irritation, redness, and skin rash around the injection site.
- Allergic reaction (hypersensitivity) Symptoms may include swelling of the face, skin rash, and sudden redness of the skin (flushing).

Reporting of side effects

If you experience any side effects, talk to your doctor or nurse, even if they are not listed in this leaflet. You can also report side effects directly through the national reporting system listed in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Loargys

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the label. The expiry date is the last day of the month stated.

Store in a refrigerator (between 2°C and 8°C). Do not freeze. Keep the container in the outer carton to protect from light.

Once removed from the refrigerator, Loargys can be stored for 2 hours at room temperature not above 25°C.

Medicines should not be disposed of via wastewater or household waste. This will help protect the environment.

6. Container Contents and Additional Information

Composition of Loargys

The active ingredient is pegzilarginasa.
Each 0.4 ml vial contains 2 mg of pegzilarginasa.
Each 1 ml vial contains 5 mg of pegzilarginasa.

The other ingredients are sodium chloride, potassium dihydrogen phosphate, dipotassium phosphate, glycerol, hydrochloric acid, sodium hydroxide, and water for injections. Loargys contains sodium and potassium (see section 2).

Appearance and Container Contents

Loargys is a colorless to slightly yellow or slightly pink, clear to slightly opalescent liquid in a transparent glass vial.

Each container contains 1 vial with 0.4 ml or 1 ml of solution for injection/infusion.

Only some pack sizes may be marketed.

Marketing Authorization Holder and Manufacturer

Immedica Pharma AB

113 63 Stockholm

Sweden

Manufacturer

Unimedic AB

Storjordenvägen 2

864 31 Matfors

Sweden

Date of Last Revision of this Leaflet

This medicinal product has been authorized under exceptional circumstances. This means that due to the rarity of this disease, it has not been possible to obtain complete information on this medicinal product.

The European Medicines Agency will review any new information that may become available every year and this leaflet will be updated as necessary.

Other Sources of Information

Detailed information on this medicinal product is available on the European Medicines Agency website:. There are also links to other websites on rare diseases and orphan medicines.

This leaflet can be found on the European Medicines Agency website in all EU/EEA languages.

You can also find this leaflet and the approved patient training material on this medicinal product by scanning the QR code below with a smartphone or through the website http://www.loargyspatient.eu

Square black and white QR code with internal modules and defined edges

Instructions for Use

The following steps describe how to prepare and administer Loargys at home, as a subcutaneous injection. If you are going to inject this medicinal product yourself, your doctor or nurse will teach you how to prepare and inject Loargys.

Do not inject this medicinal product yourself unless you have been trained and understand the steps to follow.

Your doctor will prescribe the correct dose and tell you what volume (in ml) to inject. You may need more than one vial to get the correct dose, and you may need to divide the total dose into more than one injection. Your doctor or nurse will tell you exactly what is right for you.

Each vial is for single use; always use a new vial(s) for each dose.

Loargys must not be mixed with other solutions for injection or infusion.

Do not shake.

Preparation:

Make sure you have everything you need for the injection(s):

Loargys vial(s)
A graduated syringe
1 large needle (e.g., 18 gauge) per vial, for extracting the dose
1 small needle (e.g., 26-27 gauge) per injection
Alcohol swabs
Gauze pad
Plaster, if necessary
Sharps container

Check the name and concentration of the vial to ensure it contains the correct medicinal product and that you have the correct number of vials. Check the expiry date on the container. Do not use if the product has expired.

Remove the Loargys vial(s) from the refrigerator between 15 and 30 minutesbefore the planned injection, to allow the solution to reach room temperature. Do not use external heat.

Wash your hands

The solution in the vial should be colorless to slightly yellow or slightly pink, clear to slightly opalescent (pearly). Do not use if the solution is cloudy or contains visible particles.

Place the vial on a flat, clean surface. Remove the plastic flip-off cap from the vial.

Clean the top of the vial with an alcohol swab and let it air dry. Do not touch the top of the vial or let it touch anything else once cleaned.

Withdrawal of Solution from Vial:

Place a large needle on the graduated syringe. Remove the needle cap.
Pull the plunger back to draw air into the syringe, equal to the volume to be withdrawn from the vial (in ml).
Slowly push the plunger to inject air into the vial.
Keep the needle in the vial and hold it upside down. With the needle in the solution, slowly pull the plunger to the mark equal to the required volume.
Before removing the needle from the vial, check for air bubbles in the syringe solution. If there are air bubbles, hold the vial upside down with the needle pointing upwards. Gently tap the syringe barrel with your finger. Once all air bubbles are at the top, gently push the plunger to expel the air bubbles through the needle.
Check the volume to be administered (in ml) with the syringe markings to ensure you have withdrawn the correct amount of solution.
Remove the needle from the vial, replace the needle cap, and discard it in your sharps container.
You may need to use multiple vials to withdraw the full volume (in ml). To do this, repeat steps 1-8 above for each vial needed to obtain the total dose (in ml) or as directed by your doctor or nurse. Always follow the instructions given by your doctor or nurse. Note that for each new vial, you must also use a new needle.
Place a small needle on the filled syringe and do not remove the needle cap. Make sure the needle is securely attached. Note: If the solution is not to be used immediately, protect the syringe from light. After preparation, Loargys can be stored at room temperature (up to 25°C) for a maximum of 2 hours before administration. After this time, the prepared Loargys can no longer be used and must be discarded.

Administration of the Dose:

Remove the needle cap. Hold the syringe with the needle pointing upwards and tap the syringe barrel with your finger to eliminate any air bubbles. Visually check that the volume contained in the syringe is correct. The volume per injection must not exceed 1 ml. If necessary, multiple injections should be administered in different locations.
Choose an injection site (abdomen, lateral thigh, or lateral or posterior upper arm). Alternate injection sites between doses. Do not inject into scar tissue or areas that are red, inflamed, or swollen. If injecting into the abdomen, avoid the area around the navel. If more than 1 injection is needed to administer a single dose of Loargys, the injection sites should be at least 3 cm apart.
Clean the injection site with an alcohol swab and let the skin dry.
Gently pinch the skin at the chosen injection site between your thumb and index finger.
Hold the syringe like a pencil or a dart. Insert the needle into the pinched skin at an angle of 45° to 90°.
While continuing to pinch the skin, slowly push the plunger until you have injected the desired volume. Change the injection site and ensure the new injection site is more than 3 cm away. Slowly push the plunger until you have injected the required volume. Repeat until you have injected your total dose (in ml). Always use a new small needle for each injection.Reminder:if you need to inject a volume greater than 1 ml of Loargys,
Remove the syringe by pulling it straight out. Release the pinched skin and gently press a gauze pad over the injection site for a few seconds. Apply a plaster if necessary.
Place the syringe, needles, and caps used in the sharps container. Used vials, even if not empty, must be discarded according to local instructions.

Keep track of the injection date and all the sites where you have injected; this will help you use a different injection site for the next injection.

--------------------------------------------------------------------------------------------------------------------

This information is intended for healthcare professionals only:

Loargys is indicated for intravenous infusion or subcutaneous injection.

Use aseptic technique when preparing and administering Loargys.

Do not shake.

Instructions for Preparation

Determine the total volume of Loargys to be administered (and the number of vials needed) based on the patient's weight and dose level.
Remove the vial(s) from the refrigerator to allow them to reach room temperature.
Before administration, visually inspect the vial for particles and discoloration.
- Loargys is a colorless to slightly yellow or slightly pink, clear to slightly opalescent liquid, essentially free from visible foreign particles.
- Discard any vial that is not consistent with this appearance.
Withdraw the planned dose into the syringe.

The chemical and physical stability of the prepared dose has been demonstrated for 2 hours when stored at room temperature up to 25°C or up to 4 hours if refrigerated between 2°C and 8°C. If the product is not used within these time frames, it must be discarded. From a microbiological point of view, the product must be used immediately after preparation.

For Intravenous Administration

Dilute with sodium chloride 9 mg/ml (0.9%) solution for injection to obtain the desired volume of infusion (maximum concentration of pegzilarginasa 0.5 mg/ml).
Administer the intravenous infusion over at least 30 minutes.
Do not mix other medicinal products with Loargys or infuse other medicinal products simultaneously through the same intravenous access line.

For Subcutaneous Administration

Administer the solution undiluted by subcutaneous injection in the abdomen, lateral thigh, or lateral or posterior upper arm. Alternate injection sites between doses.
Do not inject into scar tissue or areas that are red, inflamed, or swollen.
If injecting into the abdomen, avoid the area around the navel.
If more than 1 injection is needed to administer a single dose of Loargys, the injection sites should be at least 3 cm apart.

Discard the unused portion of the medicinal product.

No special requirements for disposal.

Country of registration
Spain
Active substance
pegzilarginase
Prescription required
Yes
Manufacturer
Immedica Pharma Ab
This information is for reference only and does not constitute medical advice. Always consult a licensed doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
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Online doctors for LOARGYS 5 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for LOARGYS 5 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION – subject to medical assessment and local rules.

5.0(40)

Yevgen Yakovenko

General surgery11 years of experience

Areas of medical expertise:

Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

12+ years of clinical experience in university hospitals in Germany and Spain.
International education: Ukraine – Germany – Spain.
Member of the German Society of Surgeons (BDC).
Certified in radiological diagnostics and robotic surgery.
Active participant in international medical conferences and research.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment

Antonio Cayatte

General medicine43 years of experience

His clinical background includes:

assessment of sudden or unclear symptoms
ongoing care for chronic conditions
follow-up after hospital discharge
interpretation of test results
medical support while abroad

Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

Book a video appointment

Jonathan Marshall Ben Ami

Family medicine8 years of experience

Dr. Jonathan Marshall Ben Ami is a licensed family medicine doctor in Spain. He provides comprehensive care for adults and children, combining general medicine with emergency care expertise to address both acute and chronic health concerns.

Dr. Ben Ami offers expert diagnosis, treatment, and follow-up for:

Respiratory infections (cold, flu, bronchitis, pneumonia).
ENT conditions such as sinusitis, ear infections, and tonsillitis.
Digestive issues including gastritis, acid reflux, and irritable bowel syndrome (IBS).
Urinary tract infections and other common infections.
Management of chronic diseases: high blood pressure, diabetes, thyroid disorders.
Acute conditions requiring urgent medical attention.
Headaches, migraines, and minor injuries.
Wound care, health check-ups, and ongoing prescriptions.

With a patient-focused and evidence-based approach, Dr. Ben Ami supports individuals at all stages of life — offering clear medical guidance, timely interventions, and continuity of care.

Book a video appointment

Andrei Popov

General medicine6 years of experience

Dr. Andrei Popov is a licensed pain management specialist and general practitioner based in Spain. He provides expert online care for adults dealing with both chronic and acute pain, as well as a wide range of everyday health concerns.

He specialises in diagnosing and treating pain conditions that affect quality of life, including:

Chronic pain lasting more than 3 months.
Migraines and recurring headaches.
Neck, back, lower back, and joint pain.
Post-traumatic pain following injury or surgery.
Nerve-related pain, fibromyalgia, and neuralgia.

In addition to pain management, Dr. Popov helps patients with:

Respiratory infections (colds, bronchitis, pneumonia).
High blood pressure and metabolic conditions such as diabetes.
Preventive care and routine health check-ups.

Online consultations last up to 30 minutes and include a detailed symptom review, personalised treatment planning, and medical follow-up when needed.

Dr. Popov’s approach is rooted in evidence-based medicine, combined with individualised care tailored to each patient’s history, lifestyle, and clinical needs.

Book a video appointment

Tetiana Fedoryshyn

General medicine29 years of experience

Dr Tetiana Fedoryshyn is a senior general practitioner, certified nutritionist, and psychologist with over 29 years of clinical experience. She combines classical internal medicine with modern approaches in lifestyle medicine, functional nutrition, and emotional health support.

Her focus is on helping patients regain health through deep understanding of symptoms, personalised nutrition plans, and evidence-based correction of deficiencies, stress-related conditions, and metabolic imbalances. Dr Fedoryshyn works with adults experiencing chronic conditions, fatigue, hormonal disruption, and post-stress exhaustion.

She integrates medical analysis, psychological insight, and real-life behaviour change tools to offer treatment plans tailored to each patient’s biochemistry, mental state, and lifestyle.

Main areas of practice:

Chronic condition management and medical counselling
Weight loss programmes based on metabolic profiling
Diagnosis and treatment of micronutrient deficiencies
Recovery from stress, burnout, and hormonal imbalances
Emotional support and psychosomatic symptom care

Her approach is never one-size-fits-all – each consultation begins with a deep dive into your unique health history, test results, and emotional landscape. Consultations are available in Ukrainian, Polish, and Russian.

Book a video appointment

Anna Biriukova

General medicine5 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
Leg swelling, chronic fatigue, reduced exercise tolerance.
EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
Post-COVID-19 cardiac monitoring and care.

Endocrinology – Diabetes, thyroid, metabolism:

Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
Individual treatment plans including oral medications and insulin therapy.
GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
Metabolic syndrome – obesity, lipid disorders, insulin resistance.

Gastroenterology – Digestive health:

Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).

General internal medicine and preventive care:

Respiratory infections – cough, colds, bronchitis.
Lab test analysis, therapy adjustments, medication management.
Adult vaccinations – planning, contraindications assessment.
Cancer prevention – screening strategies and risk assessment.
Holistic approach – symptom relief, complication prevention, and quality of life improvement.

Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.

Book a video appointment

Mar Tabeshadze

Endocrinology10 years of experience

Dr. Mar Tabeshadze is a licensed endocrinologist and general practitioner in Spain. She provides online consultations for adults, offering medical support for a wide range of endocrine conditions and related health concerns.

Diagnostic consultations for suspected endocrine disorders
Management of thyroid conditions, including in pregnant women
Early detection and treatment of type 1 and type 2 diabetes, with personalised therapy plans
Obesity treatment: identifying underlying causes of weight gain, combining medication and non-pharmacological strategies, and long-term support
Diagnosis and treatment of endocrine-related skin, hair, and nail issues
Ongoing care for patients with osteoporosis, pituitary, and adrenal gland disorders

Dr. Tabeshadze takes a patient-centred approach based on evidence-based medicine. Her goal is to help patients achieve hormonal balance, manage chronic conditions effectively, and improve overall well-being through targeted, personalised care.

Book a video appointment

Maryna Kuznetsova

Cardiology16 years of experience

Dr Marina Kuznetsova is an internal medicine doctor and cardiologist with a PhD in medicine. She provides online consultations for adults with chronic and acute conditions, with a strong focus on cardiovascular health. Her approach is based on current clinical guidelines and evidence-based treatment strategies.

Areas of expertise:

dyslipidaemia and lipid metabolism disorders
prevention and management of atherosclerosis
blood pressure monitoring and antihypertensive therapy
arrhythmias: diagnosis, follow-up, and treatment adjustment
cardiovascular care and recovery support after Covid-19

Dr Kuznetsova helps patients manage cardiovascular risk factors, optimise long-term treatment, and gain clarity in complex health situations – all through accessible and structured online care.

Book a video appointment

Karim BenHarbi

General medicine8 years of experience

Dr. Karim Ben Harbi is a licensed general practitioner based in Italy. He provides online consultations for adults and children, combining international clinical experience with evidence-based medicine. His care approach is focused on accurate diagnosis, preventive care, and personalised health guidance.

Dr. Ben Harbi received his medical degree from Sapienza University in Rome. His training included hands-on experience in diverse settings — tropical medicine, rural healthcare, and urban outpatient practice. He also conducted clinical research in microbiology, exploring the role of the gut microbiome in chronic gastrointestinal issues.

You can consult Dr. Ben Harbi for:

General health concerns, prevention, and primary care.
Hypertension, type 1 and type 2 diabetes, metabolic issues.
Cold, cough, flu, respiratory infections, sore throat, fever.
Chronic digestive issues: bloating, gastritis, IBS, microbiome imbalance.
Skin rashes, mild allergic reactions, basic dermatological complaints.
Medication guidance, treatment adjustments, prescription review.
Paediatric concerns — fever, infections, general well-being.
Lifestyle optimisation: stress, sleep, weight, and diet counselling.

Dr. Ben Harbi offers reliable, accessible medical support through online consultations, helping patients make informed decisions about their health with a clear, structured, and compassionate approach.

Book a video appointment

Svetlana Kolomeeva

Cardiology17 years of experience

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

High blood pressure, headaches, dizziness, swelling, palpitations.
Diagnosis and management of hypertension, arrhythmias, and tachycardia.
Metabolic syndrome, excess weight, high cholesterol.
Chronic fatigue, insomnia, poor concentration, anxiety.
Respiratory symptoms: colds, flu, sore throat, cough, fever.
Digestive issues: heartburn, bloating, constipation, IBS symptoms.
Chronic conditions: diabetes, thyroid disorders.
Interpretation of lab tests and medical reports, therapy adjustment.
Second opinion and decision-making support.
Cardiovascular disease prevention and metabolic risk reduction.
Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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