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GLUFAN 625 mg FILM-COATED TABLETS

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About the medicine

How to use GLUFAN 625 mg FILM-COATED TABLETS

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Glufan 625 mg film-coated tablets

glucosamine

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Glufan and what is it used for
  2. What you need to know before you take Glufan
  3. How to take Glufan
  4. Possible side effects
  5. Storage of Glufan
  6. Contents of the pack and further information

1. What is Glufan and what is it used for

Glucosamine is a natural product produced from glucose (a sugar). Glucosamine facilitates the formation of cartilage and joints.

Glufan is indicated for the relief of symptoms produced by mild to moderate knee osteoarthritis.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Glufan

Do not takeGlufanif:

  • You are hypersensitive (allergic) to glucosamine or any of the other components of this medicine (listed in section 6).
  • You are allergic to shellfish, as the active ingredient, glucosamine, is obtained from shellfish.

Warnings and precautions

Consult your doctor or pharmacist before starting to take Glufan.

  • If you have diabetes, you should consult your doctor before taking Glufan. More frequent monitoring of blood sugar levels may be necessary when starting treatment.
  • If you have asthma. When starting treatment with Glufan, you should be aware that symptoms may worsen.

Stop taking Glufan and consult your doctor immediately if you experience any of the following symptoms (angioedema).

  • Swelling of the face, lips, tongue, or throat
  • Difficulty swallowing
  • Skin rash and difficulty breathing

Other medicines and Glufan

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

Some types of medicines used to prevent blood clotting (e.g., warfarin, dicumarol, fenprocoumon, acenocoumarol, and fluindione). The effect of these medicines may be enhanced if used in combination with glucosamine. Therefore, patients treated with these combinations should be closely monitored at the start or end of glucosamine treatment.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before taking this medicine.

Glufan should not be administered during pregnancy and breastfeeding.

Consult your doctor or pharmacist before using any medicine.

Driving and using machines

Glufan does not affect the ability to drive or use machinery. However, if you feel tired or have a headache when taking Glufan, you should not drive or operate tools or machines.

Glufan contains yellow orange aluminium lake (E-110):

This medicine may cause allergic reactions because it contains yellow orange aluminium lake (E-110).

3. How to take Glufan

Follow exactly the administration instructions of this medicine given by your doctor or pharmacist. In case of doubt, consult your doctor or pharmacist again.

Your doctor will indicate the daily dose based on your individual characteristics.

The recommended dose is one tablet twice a day. Once symptom relief is achieved, the dose may be reduced to one tablet a day.

The tablets should be swallowed with a sufficient amount of liquid.

If you take more Glufan than you should

The signs and symptoms that may occur in case of overdose with glucosamine are headache, dizziness, disorientation, arthralgia, nausea, vomiting, diarrhea, or constipation. In case of overdose, treatment with Glufan should be discontinued.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone: 91 562 04 20, indicating the medicine and the amount ingested.

If you forget to take Glufan

Do not take a double dose to make up for forgotten doses.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects have been reported:

  • Common (may affect up to 1 in 10 people): headache, somnolence, upper abdominal discomfort.
  • Uncommon (may affect up to 1 in 100 people): skin rash, itching, redness of the skin.
  • Frequency not known (cannot be estimated from the available data): dizziness, asthma or worsening of asthma, stomach pain, diarrhea, nausea/vomiting, swelling of the face, tongue, or throat (angioedema, see "Warnings and precautions"), urticaria, worsening of glucose control in patients with diabetes mellitus, edema, e.g., of ankles, legs, and feet, liver failure (increased liver enzymes and jaundice).

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Glufan

Keep this medicine out of the sight and reach of children.

Do not store above 30°C. Store in the original package.

Do not use this medicine after the expiry date which is stated on the packaging after "EXP". The expiry date is the last day of the month shown.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and further information

Composition of Glufan

  • The active substance is glucosamine hydrochloride, which corresponds to 625 mg of glucosamine (equivalent to 750 mg of glucosamine hydrochloride).
  • The other components (excipients) are:

Core of the tablet:povidone, calcium phosphate, microcrystalline cellulose, crospovidone, and magnesium stearate.

Coating:polyvinyl alcohol, talc, lecithin, macrogol, titanium dioxide (E-171), yellow orange aluminium lake (E-110), quinoline yellow (E-104), and iron oxide yellow (E-172).

Appearance and packaging of the product.

The tablets are yellow and oval.

Glufan is available in 4 different pack sizes: 20, 60, 90, and 180 tablets.

Not all pack sizes may be marketed.

Marketing authorisation holder.

Laboratorios Farmacéuticos ROVI, S.A.

Julián Camarillo, 35

28037 – Madrid

Spain

Manufacturer

ROVI Pharma Industrial Services, S.A.

Vía Complutense 140

28805 Alcalá de Henares (Madrid)

Spain

Or

Laboratorios Farmacéuticos ROVI, S.A.

Julián Camarillo, 35

28037 Madrid

Spain

Date of last revision of this leaflet:April 2021

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for GLUFAN 625 mg FILM-COATED TABLETS

Discuss questions about GLUFAN 625 mg FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (4)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
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Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

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Endocrinology – Diabetes, thyroid, metabolism:
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General internal medicine and preventive care:
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Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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5.0 (2)
Doctor

Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

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Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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Frequently Asked Questions

Is a prescription required for GLUFAN 625 mg FILM-COATED TABLETS?
GLUFAN 625 mg FILM-COATED TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in GLUFAN 625 mg FILM-COATED TABLETS?
The active ingredient in GLUFAN 625 mg FILM-COATED TABLETS is glucosamine. This information helps identify medicines with the same composition but different brand names.
How much does GLUFAN 625 mg FILM-COATED TABLETS cost in pharmacies?
The average pharmacy price for GLUFAN 625 mg FILM-COATED TABLETS is around 6.51 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures GLUFAN 625 mg FILM-COATED TABLETS?
GLUFAN 625 mg FILM-COATED TABLETS is manufactured by Laboratorios Farmaceuticos Rovi S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of GLUFAN 625 mg FILM-COATED TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether GLUFAN 625 mg FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to GLUFAN 625 mg FILM-COATED TABLETS?
Other medicines with the same active substance (glucosamine) include ACENAM 1250 mg EFFERVSCENT TABLETS, CARTISORB 1500 mg POWDER FOR ORAL SOLUTION, DUARTRON 625 mg HARD CAPSULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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