This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.

How to use FERO-GRADUMET 105 mg PROLONGED-RELEASE TABLETS

Introduction

PACKAGE LEAFLET: INFORMATION FOR THE USER

FEROGRADUMET 105 mg prolonged-release tablets

Iron (in the form of ferrous sulfate)

Read the entire package leaflet carefully before starting to take the medication

Keep this package leaflet, as you may need to read it again.
If you have any questions, consult your doctor or pharmacist.
This medication has been prescribed to you and should not be given to others, even if they have the same symptoms, as it may harm them.
If you consider that any of the side effects you are experiencing is serious or if you notice any side effect not mentioned in this package leaflet, inform your doctor or pharmacist.

Contents of the package leaflet:

What is FEROGRADUMET and what is it used for
Before taking FEROGRADUMET
How to take FEROGRADUMET
Possible side effects
Storage of FEROGRADUMET
Additional information

1. What is FEROGRADUMET and what is it used for

FEROGRADUMET belongs to a group of medications called oral iron preparations.

FEROGRADUMET is used in adult patients for the treatment of iron deficiency anemia and iron deficiency states.

2. Before taking FEROGRADUMET

Do not take FEROGRADUMET

If you are allergic (hypersensitive) to iron or any of the other components of FEROGRADUMET.
If you have an iron overload (e.g., hemochromatosis, hemosiderosis).
If you have anemia not related to iron deficiency, such as aplastic anemia, hemolytic anemia, and sideroblastic anemia.
If you have undergone repeated blood transfusions
If you are receiving concomitant parenteral therapy with iron.
If you have chronic pancreatitis or liver cirrhosis.

Be careful with FEROGRADUMET

If you have an acute intestinal condition or liver problems.
When taking FEROGRADUMET, the stools turn dark green or black. This effect is harmless.
Due to the risk of mouth ulcers and tooth discoloration, the tablets should not be sucked, chewed, or left in the mouth, but swallowed whole with water. If you cannot follow this instruction or have difficulty swallowing, contact your doctor.
If you accidentally choke on a tablet, contact your doctor as soon as possible. This is due to the risk of ulcers and narrowing of the bronchi, which can occur if the tablet enters the airways, resulting in persistent cough, bloody cough, and/or shortness of breath, even if the choking occurred days or months before these symptoms appear. Therefore, you will need to be urgently evaluated to ensure that the tablet has not damaged your airways.

Consult your doctor if any of the above circumstances have ever occurred to you.

Use of other medications

Inform your doctor or pharmacist if you are using or have recently used other medications, including those purchased without a prescription.

FEROGRADUMET should not be administered in combination with:

iron (salts) (parenterally) due to the risk of collapse and shock attributed to the rapid release of iron complexes and transferrin saturation.
if you are taking certain antibiotics, such as tetracyclines or quinolones, you should take FEROGRADUMET at an interval of two or three hours before or after the antibiotic.
if you are taking medications with thyroxine or penicillamine, FEROGRADUMET may decrease the effect of these medications.
if you are taking antacids, calcium supplements, or medications containing bicarbonate, carbonate, oxalates, or phosphates, these may reduce iron absorption.
if you are taking medications with ascorbic acid (vitamin C), iron absorption may be altered.
if you are taking medications with chloramphenicol, the response to iron treatment may be delayed.
if you are taking medications with methyldopa, FEROGRADUMET may reduce its hypotensive effect.

Taking FEROGRADUMET with food or drinks

FEROGRADUMET should not be administered with milk or dairy products.

Certain foods, such as tea, coffee, milk, cereals, may reduce iron absorption.

Pregnancy and breastfeeding

Consult your doctor or pharmacist before using any medication.

No problems have been reported in pregnant or breastfeeding women with oral iron administration.

Driving and using machines

The influence of FEROGRADUMET on the ability to drive and use machines is zero or insignificant.

Important information about some of the components of FEROGRADUMET

This medication may cause stomach upset and diarrhea because it contains castor oil.

It may cause allergic reactions because it contains the colorant Red cochineal A (Ponceau 4R) (E-124). It may trigger asthma, especially in patients allergic to acetylsalicylic acid.

3. How to take FEROGRADUMET

Follow exactly the administration instructions of FEROGRADUMET indicated by your doctor. Consult your doctor or pharmacist if you have doubts.

The normal recommended dose for mild iron deficiency anemia, iron deficiency states, and increased iron needs is 1 tablet once a day.

For severe iron deficiency anemia, with less than 8-9 g/dl of hemoglobin, the normal recommended dose is 1 tablet in the morning and another in the afternoon.

Swallow the tablets whole with water, preferably 1 hour before or 3 hours after meals. If gastrointestinal problems are observed, the tablets can be taken after meals (lunch or dinner). Do not suck, chew, or leave the tablet in the mouth.

If you think the effect of FEROGRADUMET is too strong or too weak, inform your doctor or pharmacist.

If you take more FEROGRADUMET than you should

If you have taken more FEROGRADUMET than recommended, consult your doctor or pharmacist immediately, or call the Toxicology Information Service, phone 91 562 04 20.

If you forget to take FEROGRADUMET

In case you have forgotten a dose, take another as soon as possible and continue with the usual schedule. Do not take a double dose to make up for the forgotten doses.

Symptoms of gastrointestinal irritation with nausea and vomiting may be observed.

If you interrupt treatment with FEROGRADUMET

Your doctor will indicate the duration of treatment with FEROGRADUMET. To complete the body's iron reserves, treatment should be continued for 3 months after hemoglobin values have normalized. Do not stop treatment before, even if you feel better.

If you have any other questions about the use of this product, ask your doctor or pharmacist.

4. Possible side effects

Like all medications, FEROGRADUMET can have side effects, although not everyone will experience them.

The most frequent side effects are gastrointestinal, especially abdominal pain, stomach acid, nausea, vomiting, constipation, or diarrhea. It is common for stools to turn dark green or black due to iron excretion. This effect is harmless.

Rarely, allergic reactions may occur, such as erythema, skin rash, pruritus, and respiratory difficulties.

Frequency not known (cannot be estimated from available data):

Mouth ulcers (in case of incorrect use, when tablets are chewed, sucked, or left in the mouth).

All patients, but especially the elderly and those with swallowing difficulties, may also be at risk of throat or esophageal ulcers (the tube connecting the mouth to the stomach). If the tablet enters the airways, there may be a risk of bronchial ulcers (the main airway to the lungs), which can cause bronchial narrowing.

If you consider that any of the side effects you are experiencing is serious or if you notice any side effect not mentioned in this package leaflet, inform your doctor or pharmacist.

Reporting side effects

If you experience any type of side effect, consult your doctor, pharmacist, or nurse, even if it is a possible side effect not listed in this package leaflet. You can also report them directly through the Spanish Medicines and Health Products Agency's (AEMPS) website: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medication.

5. Storage of FEROGRADUMET

Keep out of the reach and sight of children.

Do not store above 25°C. Store in the original package.

Do not use FEROGRADUMET after the expiration date stated on the package after CAD. The expiration date is the last day of the month indicated.

Medications should not be disposed of through wastewater or household waste. Deposit the packages and medications you no longer need at the pharmacy's SIGRE point. If in doubt, ask your pharmacist how to dispose of packages and medications you no longer need. This will help protect the environment.

6. ADDITIONAL INFORMATION

Composition of FEROGRADUMET

The active ingredient is iron in the form of ferrous sulfate. Each tablet contains 325 mg of ferrous sulfate, equivalent to 105 mg of elemental iron.
The other components are: methacrylic acid-methyl methacrylate copolymer, polyethylene glycol 8000 (Macrogol 8000), magnesium stearate, povidone, castor oil, hydroxypropylmethyl cellulose 2910, ethyl cellulose, polyethylene glycol 400 (Macrogol 400), lacquer, and colorant Red cochineal A (Ponceau 4R) (E124) and titanium dioxide (E171).

Appearance and packaging of the product

Package containing 30 film-coated tablets of red color.

Marketing authorization holder and manufacturer

Teofarma Srl

Via F.lli Cervi, 8

27010 Valle Salimbene

Pavia – Italy

This package leaflet was approved in October 2018.

Detailed and updated information on this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

How much does FERO-GRADUMET 105 mg PROLONGED-RELEASE TABLETS cost in Spain ( 2025)?

The average price of FERO-GRADUMET 105 mg PROLONGED-RELEASE TABLETS in December, 2025 is around 3.28 EUR. Prices may vary depending on the region, pharmacy, and whether a prescription is required. Always check with a local pharmacy or online source for the most accurate information.

Country of registration
Spain
Average pharmacy price
3.28 EUR
Active substance
ferrous sulfate
Prescription required
Yes
Manufacturer
Teofarma S.R.L.
This information is for reference only and does not constitute medical advice. Always consult a licensed doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
Alternatives to FERO-GRADUMET 105 mg PROLONGED-RELEASE TABLETS
TARDYFERON 80 mg PROLONGED-RELEASE TABLETS
Dosage form: MODIFIED-RELEASE TABLET, 80 mg
Active substance: ferrous sulfate
Manufacturer: Pierre Fabre Iberica S.A.
Prescription required
FERBISOL 100 mg GASTRO-RESISTANT CAPSULES
Dosage form: CAPSULE, 100 mg ferrous glycinate sulfate
Active substance: ferrous glycine sulfate
Manufacturer: Ucb Pharma S.A.
Prescription required
FERRO SANOL 100 mg GASTRO-RESISTANT CAPSULES
Dosage form: CAPSULE, 100 mg
Active substance: ferrous glycine sulfate
Manufacturer: Ucb Pharma S.A.
Prescription required

Alternatives to FERO-GRADUMET 105 mg PROLONGED-RELEASE TABLETS in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to FERO-GRADUMET 105 mg PROLONGED-RELEASE TABLETS in Польша

Сорбифер Дурулес

Dosage form: Таблетки, 100 мг Fe(II) + 60 мг

Active substance: сульфат железа

Marketing authorisation holder (MAH): Egis Pharmaceuticals PLC

Prescription required

Сорбифер Дурулес

Dosage form: Таблетки, 100 мг Fe(II) + 60 мг

Active substance: сульфат железа

Marketing authorisation holder (MAH): Egis Pharmaceuticals PLC

Prescription required

Сорбифер Дурулес

Dosage form: Таблетки, 100 мг Fe(II) + 60 мг

Active substance: сульфат железа

Marketing authorisation holder (MAH): Egis Pharmaceuticals PLC

Prescription required

Тардиферон-фол

Dosage form: Таблетки, 80 мг ионов железа(II) + 0,35 мг

Active substance: сульфат железа

Marketing authorisation holder (MAH): Pierre Fabre Farmaka A.E.

Prescription required

Сорбифер Дурулес

Dosage form: Таблетки, 100 мг Fe(II) + 60 мг

Active substance: сульфат железа

Marketing authorisation holder (MAH): Egis Pharmaceuticals PLC

Prescription required

Сорбифер Дурулес

Dosage form: Таблетки, 100 мг Fe(II) + 60 мг

Active substance: сульфат железа

Marketing authorisation holder (MAH): Egis Pharmaceuticals PLC

Prescription required

Alternative to FERO-GRADUMET 105 mg PROLONGED-RELEASE TABLETS in Украина

ТАРДИФЕРОН

Dosage form: таблетки, 80 мг

Active substance: сульфат железа

Manufacturer: P'er Fabr Medikament Prodaksn

Prescription required

Online doctors for FERO-GRADUMET 105 mg PROLONGED-RELEASE TABLETS

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for FERO-GRADUMET 105 mg PROLONGED-RELEASE TABLETS – subject to medical assessment and local rules.

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Tomasz Grzelewski

Dermatology20 years of experience

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

seasonal and perennial allergies
allergic rhinitis and chronic nasal symptoms
asthma and breathing difficulties
food and medication allergies
urticaria, atopic dermatitis and skin reactions
recurrent infections in children
sports-related health questions
general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Areas of medical expertise:

Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

12+ years of clinical experience in university hospitals in Germany and Spain.
International education: Ukraine – Germany – Spain.
Member of the German Society of Surgeons (BDC).
Certified in radiological diagnostics and robotic surgery.
Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Jonathan Marshall Ben Ami

Family medicine8 years of experience

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Dr. Ben Ami offers expert diagnosis, treatment, and follow-up for:

Respiratory infections (cold, flu, bronchitis, pneumonia).
ENT conditions such as sinusitis, ear infections, and tonsillitis.
Digestive issues including gastritis, acid reflux, and irritable bowel syndrome (IBS).
Urinary tract infections and other common infections.
Management of chronic diseases: high blood pressure, diabetes, thyroid disorders.
Acute conditions requiring urgent medical attention.
Headaches, migraines, and minor injuries.
Wound care, health check-ups, and ongoing prescriptions.

With a patient-focused and evidence-based approach, Dr. Ben Ami supports individuals at all stages of life — offering clear medical guidance, timely interventions, and continuity of care.

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Hocine Lokchiri

General medicine20 years of experience

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

fever, chills, fatigue and viral symptoms
cough, sore throat, nasal congestion, breathing discomfort
bronchitis and mild asthma flare-ups
nausea, diarrhoea, abdominal pain, digestive infections
rashes, allergic reactions, redness, insect bites
muscle or joint pain, mild injuries, sprains
headache, dizziness, migraine symptoms
stress-related symptoms, sleep disturbances
questions about test results and treatment plans
management of chronic conditions in stable phases

Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

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Dr. Lokchiri’s professional training includes:

Advanced Trauma Life Support (ATLS)
Basic and Advanced Cardiac Life Support (BLS/ACLS)
Pediatric Advanced Life Support (PALS)
Prehospital Trauma Life Support (PHTLS)
eFAST and critical care transthoracic echocardiography
aviation medicine

He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.

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Karim BenHarbi

General medicine8 years of experience

Dr. Karim Ben Harbi is a licensed general practitioner based in Italy. He provides online consultations for adults and children, combining international clinical experience with evidence-based medicine. His care approach is focused on accurate diagnosis, preventive care, and personalised health guidance.

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You can consult Dr. Ben Harbi for:

General health concerns, prevention, and primary care.
Hypertension, type 1 and type 2 diabetes, metabolic issues.
Cold, cough, flu, respiratory infections, sore throat, fever.
Chronic digestive issues: bloating, gastritis, IBS, microbiome imbalance.
Skin rashes, mild allergic reactions, basic dermatological complaints.
Medication guidance, treatment adjustments, prescription review.
Paediatric concerns — fever, infections, general well-being.
Lifestyle optimisation: stress, sleep, weight, and diet counselling.

Dr. Ben Harbi offers reliable, accessible medical support through online consultations, helping patients make informed decisions about their health with a clear, structured, and compassionate approach.

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Anna Biriukova

General medicine5 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
Leg swelling, chronic fatigue, reduced exercise tolerance.
EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
Post-COVID-19 cardiac monitoring and care.

Endocrinology – Diabetes, thyroid, metabolism:

Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
Individual treatment plans including oral medications and insulin therapy.
GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
Metabolic syndrome – obesity, lipid disorders, insulin resistance.

Gastroenterology – Digestive health:

Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).

General internal medicine and preventive care:

Respiratory infections – cough, colds, bronchitis.
Lab test analysis, therapy adjustments, medication management.
Adult vaccinations – planning, contraindications assessment.
Cancer prevention – screening strategies and risk assessment.
Holistic approach – symptom relief, complication prevention, and quality of life improvement.

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Svetlana Kolomeeva

Cardiology17 years of experience

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

High blood pressure, headaches, dizziness, swelling, palpitations.
Diagnosis and management of hypertension, arrhythmias, and tachycardia.
Metabolic syndrome, excess weight, high cholesterol.
Chronic fatigue, insomnia, poor concentration, anxiety.
Respiratory symptoms: colds, flu, sore throat, cough, fever.
Digestive issues: heartburn, bloating, constipation, IBS symptoms.
Chronic conditions: diabetes, thyroid disorders.
Interpretation of lab tests and medical reports, therapy adjustment.
Second opinion and decision-making support.
Cardiovascular disease prevention and metabolic risk reduction.
Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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Mar Tabeshadze

Endocrinology10 years of experience

Dr. Mar Tabeshadze is a licensed endocrinologist and general practitioner in Spain. She provides online consultations for adults, offering medical support for a wide range of endocrine conditions and related health concerns.

Diagnostic consultations for suspected endocrine disorders
Management of thyroid conditions, including in pregnant women
Early detection and treatment of type 1 and type 2 diabetes, with personalised therapy plans
Obesity treatment: identifying underlying causes of weight gain, combining medication and non-pharmacological strategies, and long-term support
Diagnosis and treatment of endocrine-related skin, hair, and nail issues
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Dr. Tabeshadze takes a patient-centred approach based on evidence-based medicine. Her goal is to help patients achieve hormonal balance, manage chronic conditions effectively, and improve overall well-being through targeted, personalised care.

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Maryna Kuznetsova

Cardiology16 years of experience

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Areas of expertise:

dyslipidaemia and lipid metabolism disorders
prevention and management of atherosclerosis
blood pressure monitoring and antihypertensive therapy
arrhythmias: diagnosis, follow-up, and treatment adjustment
cardiovascular care and recovery support after Covid-19

Dr Kuznetsova helps patients manage cardiovascular risk factors, optimise long-term treatment, and gain clarity in complex health situations – all through accessible and structured online care.

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Antonio Cayatte

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His clinical background includes: