BERINERT 3000 IU POWDER AND SOLVENT FOR SUBCUTANEOUS INJECTION

Ask a doctor about a prescription for BERINERT 3000 IU POWDER AND SOLVENT FOR SUBCUTANEOUS INJECTION

5.0(12)

Anna Biriukova

General medicine5 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
Leg swelling, chronic fatigue, reduced exercise tolerance.
EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
Post-COVID-19 cardiac monitoring and care.

Endocrinology – Diabetes, thyroid, metabolism:

Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
Individual treatment plans including oral medications and insulin therapy.
GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
Metabolic syndrome – obesity, lipid disorders, insulin resistance.

Gastroenterology – Digestive health:

Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).

General internal medicine and preventive care:

Respiratory infections – cough, colds, bronchitis.
Lab test analysis, therapy adjustments, medication management.
Adult vaccinations – planning, contraindications assessment.
Cancer prevention – screening strategies and risk assessment.
Holistic approach – symptom relief, complication prevention, and quality of life improvement.

Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.

Book a video appointment

Maryna Kuznetsova

Cardiology16 years of experience

Dr Marina Kuznetsova is an internal medicine doctor and cardiologist with a PhD in medicine. She provides online consultations for adults with chronic and acute conditions, with a strong focus on cardiovascular health. Her approach is based on current clinical guidelines and evidence-based treatment strategies.

Areas of expertise:

dyslipidaemia and lipid metabolism disorders
prevention and management of atherosclerosis
blood pressure monitoring and antihypertensive therapy
arrhythmias: diagnosis, follow-up, and treatment adjustment
cardiovascular care and recovery support after Covid-19

Dr Kuznetsova helps patients manage cardiovascular risk factors, optimise long-term treatment, and gain clarity in complex health situations – all through accessible and structured online care.

Book a video appointment

Anna Biriukova

General medicine5 years of experience

Cardiology – Diagnosis and treatment of:

High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
Leg swelling, chronic fatigue, reduced exercise tolerance.
EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
Post-COVID-19 cardiac monitoring and care.

Endocrinology – Diabetes, thyroid, metabolism:

Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
Individual treatment plans including oral medications and insulin therapy.
GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
Metabolic syndrome – obesity, lipid disorders, insulin resistance.

Gastroenterology – Digestive health:

Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).

General internal medicine and preventive care:

Respiratory infections – cough, colds, bronchitis.
Lab test analysis, therapy adjustments, medication management.
Adult vaccinations – planning, contraindications assessment.
Cancer prevention – screening strategies and risk assessment.
Holistic approach – symptom relief, complication prevention, and quality of life improvement.

Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.

Book a video appointment

Maryna Kuznetsova

Cardiology16 years of experience

Areas of expertise:

dyslipidaemia and lipid metabolism disorders
prevention and management of atherosclerosis
blood pressure monitoring and antihypertensive therapy
arrhythmias: diagnosis, follow-up, and treatment adjustment
cardiovascular care and recovery support after Covid-19

Dr Kuznetsova helps patients manage cardiovascular risk factors, optimise long-term treatment, and gain clarity in complex health situations – all through accessible and structured online care.

Book a video appointment

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.

How to use BERINERT 3000 IU POWDER AND SOLVENT FOR SUBCUTANEOUS INJECTION

Introduction

Package Leaflet: Information for the User

Berinert 3000 UI

Powder and solvent for solution for subcutaneous injection

Human C1 esterase inhibitor

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

Keep this leaflet, you may need to read it again.
If you have any further questions, ask your doctor or pharmacist.
This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack and other information:

What is Berinert and what is it used for
What you need to know before you use Berinert
How to use Berinert
Possible side effects
Storage of Berinert
Contents of the pack and other information

1. What is Berinert and what is it used for

What is Berinert?

Berinert is presented as a powder and solvent. The prepared solution should be administered by subcutaneous injection.

Berinert is prepared from human plasma (the liquid part of the blood). The active substance is human C1 esterase inhibitor protein, obtained from plasma.

What is Berinert used for?

Berinert is used for the prevention of recurrent attacks of hereditary angioedema (HAE) in adolescent and adult patients. Hereditary angioedema is a congenital vascular disease. It is not an allergic disease. HAE is caused by insufficient, absent, or defective synthesis of C1 esterase inhibitor, which is an important protein. The disease is characterized by the following symptoms:

sudden swelling of hands and feet,
sudden swelling of the face with a feeling of tightness,
swelling of the eyelids, lips, possible swelling of the larynx (voice organ) with breathing difficulties,
swelling of the tongue,
colic-like pain in the abdominal region.

Generally, all parts of the body can be affected.

2. What you need to know before you use Berinert

The following sections contain information that your doctor should consider before administering Berinert to you.

Do not use Berinert:

If you have experienced life-threatening immediate hypersensitivity reactions, including anaphylaxis, to C1 esterase inhibitor or to any of the other components of this medicine (listed in section 6).

Tell your doctor or pharmacist if you are allergic to any medicine or any food.

Warnings and precautions

Consult your doctor or pharmacist before starting to use Berinert,

Berinert administration should be discontinued immediately (e.g., by interrupting the injection).

If you have a history of blood coagulation problems. Blood clots have occurred in patients treated with Berinert intravenously. The use of Berinert at very high doses in diseases other than HAE could increase the risk of blood clots. However, in the case of subcutaneous Berinert, there is no established relationship with blood clots at the recommended dose. Consult your doctor if you have a history of heart or blood vessel disease, infarction, blood clots, or thick blood, a permanent catheter/device in one of your veins, or have been immobilized for some time. These situations may increase the risk of developing a blood clot after using Berinert. Also, inform your doctor about the medications you are using, as some medications, such as contraceptives or certain androgens, may increase the risk of developing a blood clot.

Your doctor will carefully weigh the benefits of treatment with Berinert against the risk of these complications.

Viral safety

When administering medicines derived from human blood or plasma, certain measures must be taken to prevent infections from being passed on to patients. Such measures include:

careful selection of blood and plasma donors to exclude those who are at risk of being carriers of infectious diseases, and
testing for specific virus and infection markers in individual donations and in plasma pools.

Manufacturers of these products also include stages in the processing of blood or plasma to eliminate/inactivate viruses. Despite this, when administering medicines derived from human blood or plasma, the possibility of transmitting infectious agents cannot be entirely excluded. This also applies to emerging or unknown viruses or other types of infections.

The measures taken are considered effective for enveloped viruses such as human immunodeficiency virus (HIV, the AIDS virus), hepatitis B virus, hepatitis C virus (liver inflammation), and for non-enveloped viruses such as hepatitis A virus (liver inflammation) and parvovirus B19.

It is possible that your doctor may recommend vaccination against hepatitis A and B if you are treated periodically/repeatedly with human plasma-derived medicines.

It is strongly recommended that each time Berinert is administered, the administration date, batch number, and injected volume be recorded.

Using Berinert with other medicines

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines, including those without a prescription.
Berinert should not be mixed with other medicines and diluents in the same syringe.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Driving and using machines

Berinert does not affect your ability to drive or use machines.

Berinert contains sodium

This medicine contains 29 mg of sodium (main component of cooking/table salt) in each vial. This is equivalent to 1.5% of the maximum recommended daily sodium intake for an adult.

3. How to use Berinert

Berinert is indicated for self-administration by subcutaneous injection. You or your caregiver should be trained, as necessary, on how to administer Berinert.

Dosage

The recommended dose of Berinert is 60 IU/kg body weight.

Pediatric population

The recommended dose is the same as for adults.

If you use more Berinert than you should

No cases of overdose have been reported.

Reconstitution and administration

If your doctor decides that you can treat yourself at home, they will give you detailed instructions. You will be given a diary where you will record each injection administered at home, which you will bring with you every time you visit the doctor. You or your caregiver will be regularly reviewed on how to administer the injections to ensure that they are done correctly over time.

General instructions

The powder must be dissolved and withdrawn from the vial under aseptic conditions. Use the syringe provided with the product.
The prepared solution should be clear and transparent to slightly opalescent. After filtering or transferring the solution (see below), it should be visually checked for particles or discoloration before administration.
Do not use the solution if it is visibly cloudy or contains particles or residues.
Any unused medicine or residual material should be disposed of in accordance with local regulations and following your doctor's instructions.

Reconstitution

Before opening any vial, allow the Berinert powder and solvent to reach room temperature. To do this, you can leave the vials at room temperature for about an hour or hold them in your closed hands for a few minutes. DO NOT expose the vials to direct heat. The vials should not be heated to a temperature above body temperature (37 °C).

Carefully remove the protective caps from the solvent vial and the powder vial. Clean the exposed rubber stoppers of both vials with an alcohol swab and let them dry. You can now transfer the solvent to the powder vial using the included administration system (Mix2Vial). Please follow the instructions below:

1	Open the Mix2Vial blister by tearing off the seal. Do not remove the Mix2Vial from the blister.
2	Place the solvent vial on a clean and flat surface and hold it firmly. Hold the Mix2Vial along with the blister and push the blue terminal downwards, engaging it with the solvent vial stopper.
3	Carefully remove the blister from the Mix2Vial by holding the edge and pulling it vertically upwards. Make sure you only remove the blister and not the Mix2Vial.
4	Place the lyophilized powder vial on a flat and firm surface. Invert the solvent vial with the attached Mix2Vial and push the transparent adapter terminal downwards, engaging it with the powder vial stopper. The solvent will automatically transfer to the lyophilized powder vial.
5	With one hand, hold the vial with the attached Mix2Vial and, with the other hand, hold the solvent vial. Carefully unscrew the system in a counterclockwise direction, separating it into two pieces. Discard the solvent vial with the attached blue Mix2Vial adapter.
6	Subject the reconstituted solution vial with the attached transparent adapter to gentle rotational movements until the substance is completely dissolved. Do not shake.
7	Fill an empty and sterile syringe with air. Use the syringe provided with the product. Holding the solution vial in a vertical position, connect the syringe to the Luer Lock adapter of the attached Mix2Vial by screwing it clockwise. Inject the air into the solution vial.

Transfer and administration

8	Holding the syringe plunger down, invert the system and slowly draw the solution into the syringe by pulling the syringe plunger back.
9	Once the solution has been transferred to the syringe, firmly hold the syringe body (keeping the plunger down) and disconnect the transparent Mix2Vial adapter from the syringe by unscrewing it counterclockwise.

Administration

Self-administration (subcutaneous administration)

Your doctor will teach you how to administer Berinert safely. Once you know how to self-administer the medicine, follow the instructions provided below.

Table 2. Instructions for self-administration of Berinert

Step 1: Attach the accessories

Take the Berinert syringe, the following disposable accessories, and other items (needles or other containers, treatment diary or logbook):

Hypodermic needle or subcutaneous infusion set
Sterile needle (use a silicone-free needle)
Alcohol swabs
Gloves (if recommended by your healthcare professional)

Step 2: Clean the surface

Thoroughly clean a table or flat surface using alcohol swabs.

Step 3: Wash your hands

Wash and dry your hands thoroughly.
If you have been recommended to wear gloves during infusion preparation, put on the gloves.

Step 4: Prepare the injection site

Unless your doctor has told you to use another area, select a site on your abdomen (belly) for the injection (Figure 1).
Use a different site from your last injection; you should change the injection sites.
New injection sites should be at least 5 inches (5 centimeters) away from the site of the previous injection.
Never inject into an area where the skin appears itchy, swollen, painful, wounded, or red.
Avoid injecting into areas with scars or stretch marks.
Clean the skin at the injection site with an alcohol swab and let the skin dry (Figure 2).

Female human torso with breast contour and marks indicating possible injection sites on abdomen and ribs

Figure 1

Needle inserted into the skin at a 45-degree angle and a curved arrow indicating the direction of injection

Figure 2

Step 5: Injection into the abdominal area

As indicated by your healthcare professional:

Attach a hypodermic needle or subcutaneous infusion set to the syringe according to your healthcare professional's instructions. Prepare the needle or tubing as necessary and as you have been taught.

Injection with a hypodermic needle:

Insert the needle into the skin fold (Figure 3).

Injection with a subcutaneous infusion set:

Insert the needle into the skin fold (Figure 4).

Hand holding syringe with needle inserted into skin showing subcutaneous injection angle

Figure 3

Hands holding a device with cable and connector, possibly an electrode or sensor, on the skin

Figure 4

Step 6: Clean up

After injecting the complete dose of Berinert, remove the needle.
Dispose of any unused solution and administration equipment according to local requirements.

Step 7: Record the treatment

Each time you use Berinert, record the batch number on the Berinert vial label in your treatment diary or logbook with the date and time of infusion .

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Immediately contact your doctor

Side effects with Berinert are rare.

The following side effects have been observed very frequently (may affect more than 1 in 10 people):

Reactions at the injection site (bruising, feeling of cold, suppuration, erythema, hematoma, hemorrhage, hardening, edema, pain, pruritus, rash, scarring, swelling, urticaria, heat).
Nasopharyngitis (stuffy nose, sneezing, runny eyes).

The following side effects have been observed frequently (may affect up to 1 in 10 people):

Hypersensitivity or allergic reactions (such as hypersensitivity, pruritus, rash, and urticaria)
Dizziness

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Berinert

Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the label and carton after EXP.
Do not store above 30 °C.
Do not freeze.
Store the vial in the outer packaging to protect it from light.
Berinert does not contain preservatives, so the prepared solution should be used immediately.
If the prepared solution is not administered immediately, it should be used within 8 hours and only stored in the vial.

6. Container Contents and Additional Information

Berinert Composition

The active ingredient is:

Human C1 esterase inhibitor (3,000 IU/vial; after reconstitution with 5.6 ml of water for injectable preparations 500 IU/ml).

"Thisinformation is intended only for healthcare professionals".

The other components are:

Glycine, sodium chloride, sodium citrate.

Solvent:water for injectable preparations.

Product Appearance and Container Contents

Berinert is presented as a white powder and is supplied with water for injectable preparations as a solvent.

The prepared solution should be transparent and clear to slightly opalescent.

Presentation

A container contains:

1 vial with powder

1 vial with 5.6 ml of water for injectable preparations

1 transfer device with 20/20 filter

Administration equipment (inner box):

1 disposable 10 ml syringe

1 hypodermic needle

1 subcutaneous injection device (butterfly)

2 alcohol swabs

1 dressing

Multiple packaging of 5 x 3,000 IU, including a box with 5 administration equipment.

Multiple packaging of 20 x 3,000 IU, including 4 boxes with 5 administration equipment.

Only some pack sizes may be marketed.

Marketing Authorization Holder and Manufacturer

CSL Behring GmbH

Emil-von-Behring-Strasse 76

35041 Marburg

Germany

For further information about this medicinal product, please contact the local representative of the marketing authorization holder:

CSL Behring S.A.

c/ Tarragona 157, 18th floor

08014 Barcelona

Spain

This medicinal product is authorized in the Member States of the European Economic Areaand in the United Kingdom (Northern Ireland)under the following names:

Berinert 3000 I.E. Powder and solvent for solution for injection Austria

Berinert 3000 IE, powder and solvent for solution for injection Belgium, Netherlands

Berinert 3000 Cyprus, Germany, Greece, Poland, Portugal

???????? 3000, ???? ? ???????????

?? ??????????? ???????

C1- ????????? ?????????, ??????? Bulgaria

Berinert 3000 IU Czech Republic, Slovakia

Berinert 3000 IU powder and solvent for solution for injection _______________________________ Croatia

Berinert Denmark, Italy

Berinert SC Estonia

Berinert 3000 IU, powder and solvent for solution for injection Finland

Berinert 3000 UI, powder and solvent for injectable solution France, Luxembourg

Berinert 3000 NE powder and solvent for injectable solution Hungary

Berinert 3000 a.e. powder and solvent, solution for injection Iceland

Human C1-esterase inhibitor CSL Behring 3000 TV powder and solvent for injectable solution Lithuania

Berinert 3000 IU powder and liquid for injectable solution, solution Norway

Berinert 3000 3000 UI, powder and solvent for injectable solution Romania

Berinert 3000 i.e. powder and vehicle for solution for injection Slovenia

Berinert 3000 UI powder and solvent for subcutaneous injectable solution Spain

Berinert 3000 IE, powder and liquid for injectable solution, solution Sweden

Berinert 3000 IU Powder and solvent for solution for injection _____________________ United Kingdom, Malta, Ireland

Date of last revision of this leaflet:October 2021

Detailed and updated information on this medicinal product is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es

Thisinformation is intended only for healthcare professionals

QUALITATIVE AND QUANTITATIVE COMPOSITION

The potency of human C1 esterase inhibitor is expressed in International Units (IU), which is related to the current WHO standard for C1 esterase inhibitor products.

Country of registration
Spain
Active substance
c1-inhibitor, plasma derived
Prescription required
Yes
Manufacturer
Csl Behring Gmbh
This information is for reference only and does not constitute medical advice. Always consult a licensed doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
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Online doctors for BERINERT 3000 IU POWDER AND SOLVENT FOR SUBCUTANEOUS INJECTION

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for BERINERT 3000 IU POWDER AND SOLVENT FOR SUBCUTANEOUS INJECTION – subject to medical assessment and local rules.

5.0(12)

Anna Biriukova

General medicine5 years of experience

Cardiology – Diagnosis and treatment of:

High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
Leg swelling, chronic fatigue, reduced exercise tolerance.
EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
Post-COVID-19 cardiac monitoring and care.

Endocrinology – Diabetes, thyroid, metabolism:

Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
Individual treatment plans including oral medications and insulin therapy.
GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
Metabolic syndrome – obesity, lipid disorders, insulin resistance.

Gastroenterology – Digestive health:

Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).

General internal medicine and preventive care:

Respiratory infections – cough, colds, bronchitis.
Lab test analysis, therapy adjustments, medication management.
Adult vaccinations – planning, contraindications assessment.
Cancer prevention – screening strategies and risk assessment.
Holistic approach – symptom relief, complication prevention, and quality of life improvement.

Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.

Book a video appointment

Maryna Kuznetsova

Cardiology16 years of experience

Areas of expertise:

dyslipidaemia and lipid metabolism disorders
prevention and management of atherosclerosis
blood pressure monitoring and antihypertensive therapy
arrhythmias: diagnosis, follow-up, and treatment adjustment
cardiovascular care and recovery support after Covid-19

Dr Kuznetsova helps patients manage cardiovascular risk factors, optimise long-term treatment, and gain clarity in complex health situations – all through accessible and structured online care.

Book a video appointment

Taisiya Minorskaya

Family medicine12 years of experience

Dr Taisiya Minorskaya is a family medicine doctor with an official licence to practise in Spain and over 12 years of clinical experience. She provides online consultations for adults and children, combining evidence-based medicine with a personalised, modern European approach.

She helps with:

Viral infections and cold symptoms (flu, sore throat, cough, runny nose)
Review and adjustment of antibiotics
Skin rashes and allergic reactions
Chronic condition flare-ups, high blood pressure, headaches, fatigue
Lab and test interpretation
Medication review and adaptation to European standards
Patient navigation: what tests are needed, which specialists to see, when an in-person visit is required

Dr Minorskaya also specialises in the diagnosis and management of gastrointestinal conditions, including bloating, abdominal pain, chronic nausea, IBS, and SIBO. She supports patients with unexplained physical symptoms that may be linked to somatisation or stress, helping them find relief and improve quality of life.

She offers care for people undergoing GLP-1 therapy (Ozempic, Mounjaro, and others) for weight management. Her support follows Spanish clinical guidelines, from treatment planning and side effect counselling to regular follow-ups and coordination with private or public healthcare providers.

Book a video appointment

Yevgen Yakovenko

General surgery11 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

12+ years of clinical experience in university hospitals in Germany and Spain.
International education: Ukraine – Germany – Spain.
Member of the German Society of Surgeons (BDC).
Certified in radiological diagnostics and robotic surgery.
Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment

Antonio Cayatte

General medicine43 years of experience

Dr Antonio Cayatte is a physician in General and Acute Medicine with over 30 years of experience across clinical care, medical research, and education. He offers online consultations for adults with a wide range of symptoms, both acute and chronic.

His clinical background includes:

assessment of sudden or unclear symptoms
ongoing care for chronic conditions
follow-up after hospital discharge
interpretation of test results
medical support while abroad

Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association.

Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

Book a video appointment

Andrei Popov

General medicine6 years of experience

Dr. Andrei Popov is a licensed pain management specialist and general practitioner based in Spain. He provides expert online care for adults dealing with both chronic and acute pain, as well as a wide range of everyday health concerns.

He specialises in diagnosing and treating pain conditions that affect quality of life, including:

Chronic pain lasting more than 3 months.
Migraines and recurring headaches.
Neck, back, lower back, and joint pain.
Post-traumatic pain following injury or surgery.
Nerve-related pain, fibromyalgia, and neuralgia.

In addition to pain management, Dr. Popov helps patients with:

Respiratory infections (colds, bronchitis, pneumonia).
High blood pressure and metabolic conditions such as diabetes.
Preventive care and routine health check-ups.

Online consultations last up to 30 minutes and include a detailed symptom review, personalised treatment planning, and medical follow-up when needed.

Dr. Popov’s approach is rooted in evidence-based medicine, combined with individualised care tailored to each patient’s history, lifestyle, and clinical needs.

Book a video appointment

Jonathan Marshall Ben Ami

Family medicine8 years of experience

Dr. Jonathan Marshall Ben Ami is a licensed family medicine doctor in Spain. He provides comprehensive care for adults and children, combining general medicine with emergency care expertise to address both acute and chronic health concerns.

Dr. Ben Ami offers expert diagnosis, treatment, and follow-up for:

Respiratory infections (cold, flu, bronchitis, pneumonia).
ENT conditions such as sinusitis, ear infections, and tonsillitis.
Digestive issues including gastritis, acid reflux, and irritable bowel syndrome (IBS).
Urinary tract infections and other common infections.
Management of chronic diseases: high blood pressure, diabetes, thyroid disorders.
Acute conditions requiring urgent medical attention.
Headaches, migraines, and minor injuries.
Wound care, health check-ups, and ongoing prescriptions.

With a patient-focused and evidence-based approach, Dr. Ben Ami supports individuals at all stages of life — offering clear medical guidance, timely interventions, and continuity of care.

Book a video appointment

Alexandra Alexandrova

General medicine8 years of experience

Dr Alexandra Alexandrova is a licensed general medicine doctor in Spain, specialising in trichology, nutrition, and aesthetic medicine. She offers online consultations for adults, combining a therapeutic approach with personalised care for hair, scalp, and overall health.

Areas of expertise:

Hair loss in women and men, postpartum hair loss, androgenetic and telogen effluvium.
Scalp conditions: seborrheic dermatitis, psoriasis, scalp irritation, dandruff.
Chronic conditions: hypertension, diabetes, metabolic disorders.
Online trichology consultation: customised treatment plans, nutritional support, hair growth stimulation.
Hair loss prevention: hormonal imbalance, stress factors, haircare strategies.
Routine health check-ups, prevention of cardiovascular and metabolic diseases.
Personalised nutritional advice to improve hair strength, skin health, and hormonal balance.
Aesthetic medicine: non-invasive strategies to enhance skin quality, tone, and metabolic wellness.

Dr Alexandrova follows an evidence-based and holistic approach: online consultations with a therapist and trichologist on Oladoctor provide professional support for hair, scalp, and overall health — all from the comfort of your home.

Book a video appointment