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CARGLUMIC ACID WAYMADE 200 mg DISPERSIBLE TABLETS

Ask a doctor about a prescription for CARGLUMIC ACID WAYMADE 200 mg DISPERSIBLE TABLETS

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Doctor

Nuno Tavares Lopes

Family medicine17 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC. He offers online consultations in Portuguese, English, and Spanish — combining global expertise with a patient-centred, evidence-based approach.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.
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Doctor

Taisiya Minorskaya

Pediatrics12 years of experience

Dr. Taisiya Minorskaya is a licensed paediatrician and family medicine doctor based in Spain. She provides online consultations for children, adolescents, and adults, offering comprehensive care for acute symptoms, chronic conditions, prevention, and lifestyle-related concerns.

Support for children:

  • acute infections, cough, sore throat, fever, rashes;
  • sleep issues, developmental delays, nutrition and emotional support;
  • asthma, allergies, atopic dermatitis, and other chronic conditions;
  • routine vaccinations, preventive check-ups, health monitoring;
  • parental guidance on care, lifestyle, and adaptation.
Support for adults:
  • acute symptoms: infections, pain, blood pressure issues, digestive or sleep problems;
  • management of chronic conditions: hypertension, thyroid issues, metabolic disorders;
  • mental health support: anxiety, fatigue, mood swings;
  • weight management and obesity care: medical evaluation, personalised nutrition and activity plans, pharmacotherapy if needed;
  • preventive care, health screenings, test interpretation, and treatment adjustments.
Dr. Minorskaya combines an evidence-based approach with a holistic understanding of each patient’s age, needs, and family context. With her dual specialisation, she offers long-term medical support for both children and adults, helping improve quality of life and maintain overall health at every stage.
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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use CARGLUMIC ACID WAYMADE 200 mg DISPERSIBLE TABLETS

Introduction

Package Leaflet: Information for the User

Carglumic Acid Waymade 200 mg Dispersible Tablets EFG

carglumic acid

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others, as it may harm them, even if their symptoms are the same as yours.
  • If you experience any of the side effects, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. See section 4.

In this leaflet:

  1. What Carglumic Acid is and what it is used for
  1. What you need to know before you take Carglumic Acid
  1. How to take Carglumic Acid
  1. Possible side effects
  • Storage of Carglumic Acid
  1. Further information

1. What Carglumic Acid is and what it is used for

The name of this medicine is Carglumic Acid Waymade 200 mg Dispersible Tablets. In this leaflet, it will be called Carglumic Acid.

Carglumic Acid can help eliminate high levels of ammonia in the blood. Ammonia is especially toxic to the brain and can cause, in severe cases, a decrease in the level of consciousness and coma.

Hyperammonemia can be due to

  • the lack of a specific liver enzyme (N-acetylglutamate synthase). Patients with this rare disorder are unable to eliminate nitrogen waste, which increases after eating proteins.

This disorder persists throughout the patient's life, so this treatment is necessary for life

  • isovaleric acidemia, methylmalonic acidemia, or propionic acidemia. Patients who suffer from one of these disorders need treatment during the hyperammonemia crisis.

.

2. What you need to know before you start taking Carglumic Acid

Do not take Carglumic Acid:

  • if you are allergic (hypersensitive) to carglumic acid or any of the other ingredients of this medicine (see section 6 for the complete list of ingredients).
  • during breastfeeding.

Warnings and precautions

Treatment with carglumic acid should be initiated under the supervision of a doctor with experience in the treatment of metabolic disorders.

Your doctor will evaluate your individual response to carglumic acid before starting any long-term treatment. The dose should be adjusted individually to maintain normal blood ammonia levels.

Your doctor may prescribe you arginine supplements or limit your protein intake.

In order to monitor your disease and treatment, your doctor may periodically examine your liver, kidneys, heart, and blood.

Use of other medicines

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines.

Use of Carglumic Acid with food and drinks

Carglumic Acid should be taken orally before main meals or food intake.

The tablets should be dispersed in a minimum of 5 to 10 ml of water and taken immediately. The suspension has a slightly acidic taste.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before taking this medicine.

Pregnancy

The effects of carglumic acid on pregnancy and the fetus are unknown. Please consult your doctor if you are pregnant or plan to become pregnant.

Breastfeeding

You should not breastfeed your child if you take Carglumic Acid. It has not been studied whether carglumic acid passes into human breast milk. However, it has been shown that carglumic acid is present in the milk of lactating rats, with possible toxic effects on the suckling pups.

Driving and using machines

The effects on the ability to drive and use machines are unknown.

Carglumic Acid contains sodium.

The maximum recommended daily dose of this product contains 396 mg of sodium (main component of table salt/cooking salt). This is equivalent to 20% of the maximum recommended daily sodium intake for an adult.

Consult your doctor or pharmacist if you need 132 or more tablets per day for a prolonged period, especially if you have been recommended a low-salt (sodium) diet.

3. How to take Carglumic Acid

Follow exactly the administration instructions of this medicine indicated by your doctor. Consult your doctor or pharmacist if you have any doubts.

The usual dose:

The initial daily dose is usually 100 mg per kg of body weight, up to a maximum of 250 mg per kg of body weight (for example, if you weigh 10 kg, you should take 1 g per day, or 5 tablets).

For patients with N-acetylglutamate synthase deficiency, the long-term daily dose usually ranges from 10 mg to 100 mg per kg of body weight.

Your doctor will determine the suitable dose for you to maintain normal blood ammonia levels.

Carglumic Acid should be administered ONLY orally or through a nasogastric tube (using a syringe if necessary).

When the patient is in hyperammonemic coma, carglumic acid is administered by rapid administration with a syringe through the tube used for feeding.

Tell your doctor if you have kidney impairment. Your daily dose should be reduced.

If you take more Carglumic Acid than you should

If you accidentally take too many tablets, inform your doctor immediately or contact the nearest hospital. Bring the package and leaflet of the medicine with you.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone: 91.562.04.20, indicating the medicine and the amount ingested

If you forget to take Carglumic Acid

If you forget to take a dose, take the next one at the usual time. DO NOT TAKE a double dose to make up for the missed individual dose.

If you stop taking Carglumic Acid:

Do not stop taking carglumic acid without informing your doctor.

If you have any other questions about the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, Carglumic Acid can cause side effects, although not everybody gets them.

The following side effects have been reported:

  • Common (may affect up to 1 in 10 people):increased sweating
  • Uncommon (may affect up to 1 in 100 people):decreased heart rate, diarrhea, fever, vomiting, increased aminotransferases (enzymes that may indicate liver damage)
  • Frequency not known: skin rash.

If you experience any of the side effects, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

Reporting of side effects

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. You can also report them through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Carglumic Acid

Keep out of sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton, blister or bottle after EXP. The expiry date is the last day of the month shown.

Bottle

This medicine does not require any special storage conditions.

After opening the tablet container for the first time: do not refrigerate or freeze. Discard 1 month after first opening.

Keep the container tightly closed to protect it from moisture.

Blister

This medicine does not require any special storage conditions.

Medicines should not be disposed of via wastewater or household waste. Return any unused medicine to your pharmacist. This will help to protect the environment.

6. Further information

Composition of Carglumic Acid

  • The active substance is carglumic acid. Each tablet contains 200 mg of carglumic acid.
  • The other ingredients are microcrystalline cellulose, sodium croscarmellose, sodium lauryl sulfate, anhydrous colloidal silica, and sodium stearyl fumarate.

Appearance and packaging of the product

Carglumic Acid Waymade 200 mg Dispersible Tablets are white or almost white, bar-shaped tablets, 18 mm x 6 mm, with 3 break lines on both sides and engraved with "N" on one side.

The tablets can be divided into equal doses.

Carglumic Acid is available in plastic containers or blister packs of 5, 15, and 60 tablets.

Not all pack sizes may be marketed.

Marketing authorisation holder

Waymade B.V.

Herikerbergweg 88,

1101 CM Amsterdam,

Netherlands

Manufacturer

Drehm Pharma GmbH

Grünbergstraße 15/3/3,

1120 Wien

Austria

or

Waymade B.V.

Herikerbergweg 88,

1101 CM Amsterdam,

Netherlands

You can obtain further information on this medicine by contacting the local representative of the Marketing Authorisation Holder.

Aurovitas Spain, S.A.U.

Avda. de Burgos, 16-D

28036 Madrid

Spain

Date of last revision of this leaflet:August 2024

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS): http://www.aemps.gob.es/.

Online doctors for CARGLUMIC ACID WAYMADE 200 mg DISPERSIBLE TABLETS

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for CARGLUMIC ACID WAYMADE 200 mg DISPERSIBLE TABLETS – subject to medical assessment and local rules.

5.0(37)
Doctor

Yevgen Yakovenko

General surgery11 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Doctor

Duarte Meneses

Family medicine4 years of experience

Dr. Duarte Meneses is a licensed family medicine and general practice doctor based in Portugal, with additional expertise in occupational health. He provides online consultations for adults, offering medical support for both acute symptoms and chronic health conditions.

  • Common symptoms such as fever, sore throat, cough, fatigue, or digestive issues
  • Chronic conditions including hypertension, diabetes, high cholesterol, and thyroid problems
  • Mental health concerns such as stress, sleep issues, anxiety, and burnout
  • Preventive care: health check-ups, lifestyle advice, and follow-up for existing conditions
  • Work-related health questions, sick leave documentation, and medical guidance for returning to work
Dr. Meneses graduated from the University of Beira Interior and has years of experience working with diverse patient populations. He is fluent in Portuguese, English, Spanish, and French.

His approach is friendly, clear, and focused on delivering practical medical advice tailored to each patient’s needs.

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Doctor

Sergio Correa

General medicine7 years of experience

Dr. Sergio Correa is a licensed general practitioner, aesthetic medicine specialist, and trichologist with experience in emergency care and preventive health. He offers online consultations in English and Spanish, supporting adult patients with a wide range of medical concerns – from acute symptoms to chronic condition management.

His areas of focus include:

  • General and urgent care: fever, fatigue, infections, digestive issues, respiratory symptoms, and other common concerns
  • Chronic condition support: hypertension, high cholesterol, diabetes, thyroid issues
  • Aesthetic medicine and dermatology: acne, skin ageing, hyperpigmentation, personalised skincare guidance
  • Trichology: hair loss, scalp conditions, treatment strategies for men and women
  • Preventive care: health check-ups, lifestyle advice, second opinions

Dr. Correa combines medical knowledge with an aesthetic and holistic approach to help patients improve both health and quality of life.

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Doctor

Svetlana Kovalenko

Family medicine14 years of experience

Dr Svetlana Kovalenko is a family medicine doctor with over 14 years of experience and a medical degree from Kharkiv National Medical University. She offers online consultations for adults, supporting patients with both acute and chronic conditions, preventive care, and personalised medical advice.

What patients commonly consult her for:

  • High blood pressure, type 2 diabetes, cholesterol management
  • Cold and flu symptoms: fever, cough, sore throat
  • Fatigue, sleep problems, headaches, general discomfort
  • Ongoing care for chronic conditions and medication review
  • Help interpreting test results and lab reports
  • Preventive check-ups and advice on healthy lifestyle habits

Dr Kovalenko combines evidence-based practice with a respectful, patient-centred approach. She takes time to explain, listens attentively, and helps each person make confident, informed decisions about their health.

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Doctor

Roman Raevskii

Oncology6 years of experience

Dr. Roman Raevskii is an oncologist and general practitioner. He provides online consultations focused on cancer-related care, early diagnosis, and personalised treatment – combining clinical expertise with a patient-centred approach.

Dr. Raevskii provides medical care in the following areas:

  • Diagnosis and management of common conditions: hypertension, diabetes, respiratory and digestive disorders.
  • Oncological consultations: early cancer detection, risk evaluation, and treatment navigation.
  • Supportive care for oncology patients — pain control, symptom relief, and side effect management.
  • Preventive medicine and health screenings.
  • Development of tailored treatment plans based on clinical guidelines.

With a patient-centred approach, Dr. Raevskii helps individuals manage both chronic illnesses and complex oncological cases. His consultations are guided by current medical standards and adapted to each patient’s needs.

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Doctor

Andrei Popov

General medicine6 years of experience

Dr. Andrei Popov is a licensed pain management specialist and general practitioner based in Spain. He provides expert online care for adults dealing with both chronic and acute pain, as well as a wide range of everyday health concerns.

He specialises in diagnosing and treating pain conditions that affect quality of life, including:

  • Chronic pain lasting more than 3 months.
  • Migraines and recurring headaches.
  • Neck, back, lower back, and joint pain.
  • Post-traumatic pain following injury or surgery.
  • Nerve-related pain, fibromyalgia, and neuralgia.
In addition to pain management, Dr. Popov helps patients with:
  • Respiratory infections (colds, bronchitis, pneumonia).
  • High blood pressure and metabolic conditions such as diabetes.
  • Preventive care and routine health check-ups.

Online consultations last up to 30 minutes and include a detailed symptom review, personalised treatment planning, and medical follow-up when needed.

Dr. Popov’s approach is rooted in evidence-based medicine, combined with individualised care tailored to each patient’s history, lifestyle, and clinical needs.

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Doctor

Mar Tabeshadze

Endocrinology10 years of experience

Dr. Mar Tabeshadze is a licensed endocrinologist and general practitioner in Spain. She provides online consultations for adults, offering medical support for a wide range of endocrine conditions and related health concerns.

  • Diagnostic consultations for suspected endocrine disorders
  • Management of thyroid conditions, including in pregnant women
  • Early detection and treatment of type 1 and type 2 diabetes, with personalised therapy plans
  • Obesity treatment: identifying underlying causes of weight gain, combining medication and non-pharmacological strategies, and long-term support
  • Diagnosis and treatment of endocrine-related skin, hair, and nail issues
  • Ongoing care for patients with osteoporosis, pituitary, and adrenal gland disorders
Dr. Tabeshadze takes a patient-centred approach based on evidence-based medicine. Her goal is to help patients achieve hormonal balance, manage chronic conditions effectively, and improve overall well-being through targeted, personalised care.
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Doctor

Maryna Kuznetsova

Cardiology16 years of experience

Dr Marina Kuznetsova is an internal medicine doctor and cardiologist with a PhD in medicine. She provides online consultations for adults with chronic and acute conditions, with a strong focus on cardiovascular health. Her approach is based on current clinical guidelines and evidence-based treatment strategies.

Areas of expertise:

  • dyslipidaemia and lipid metabolism disorders
  • prevention and management of atherosclerosis
  • blood pressure monitoring and antihypertensive therapy
  • arrhythmias: diagnosis, follow-up, and treatment adjustment
  • cardiovascular care and recovery support after Covid-19
Dr Kuznetsova helps patients manage cardiovascular risk factors, optimise long-term treatment, and gain clarity in complex health situations – all through accessible and structured online care.
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