Bg pattern

PRESINEX 0.1 mg TABLETS

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use PRESINEX 0.1 mg TABLETS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

PACKAGE LEAFLET: INFORMATION FOR THE USER

PRESINEX 0.1 mg tablets

Desmopressin

Read all of this leaflet carefully before you start taking this medicine.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.

Contents of the pack:

  1. What PRESINEX 0.1 mg tablets are and what they are used for
  2. Before you take PRESINEX 0.1 mg tablets
  3. How to take PRESINEX 0.1 mg tablets
  4. Possible side effects
  5. Storing PRESINEX 0.1 mg tablets
  6. Further information

1. What PRESINEX 0.1 mg tablets are and what they are used for

Presinex tablets work at the level of the kidneys. The kidneys control the body's fluid balance. Presinex tablets are similar to a natural hormone called vasopressin. Vasopressin is secreted in the pituitary gland (an organ in the brain) and regulates the amount of urine produced by the kidneys.

Presinex 0.1 mg tablets are indicated for:

  • Treatment of central diabetes insipidus due to insufficient production of vasopressin, as a result of a primary or acquired alteration in the pituitary gland
  • Treatment of urinary incontinence (nocturnal enuresis) after excluding any physical cause, in patients over 5 years of age with normal urine concentration capacity.
Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. BEFORE YOU TAKE PRESINEX 0.1 mg tablets

Do not take PRESINEX 0.1 mg tablets

  • If you are allergic (hypersensitive) to desmopressin or any of the other ingredients of Presinex 0.1 mg tablets
  • If you have habitual or psychogenic polydipsia (excessive thirst)
  • If you have known hyponatremia (low sodium levels)
  • If you have severe heart failure, as Presinex may cause vasodilation, especially at high doses.

Take special care with PRESINEX 0.1 mg tablets

If you have primary nocturnal enuresis, be careful to restrict fluid intake by not drinking between 1 hour before administration and until the next morning (at least 8 hours).

In elderly patients or those with heart problems, special precautions should be taken with Presinex 0.1 mg tablets.

If you have chronic kidney disease, the effect of Presinex 0.1 mg tablets is reduced.

If you experience diarrhea or vomiting, please stop treatment with Presinex 0.1 mg tablets and inform your doctor.

Treatment without reducing fluid intake may cause water retention and/or decreased sodium levels in the blood, accompanied by symptoms and signs of alarm (headache, nausea/vomiting, weight gain, and in severe cases, convulsions). See section 4. Possible Side Effects

Special care should be taken to avoid decreased sodium levels in the blood in the following cases:

  • Generalized infections, fever, and diabetes insipidus (inappropriate ADH secretion syndrome)
  • Diseases where diuretic medications are used to increase urine production
  • Treatment with medications that may cause diabetes insipidus on their own, such as antidepressant medications: tricyclic antidepressants, for example, amitriptyline, selective serotonin reuptake inhibitors, for example, fluoxetine, chlorpromazine, and carbamazepine.
  • Treatment with non-steroidal anti-inflammatory drugs (NSAIDs) such as acetylsalicylic acid.

Consult your doctor if you experience any of these symptoms or have experienced them before.

Using other medicines:

Please inform your doctor or pharmacist if you are using or have recently used any other medicines, including those obtained without a prescription.

Please inform your doctor if you are taking:

  • Any pain or anti-inflammatory medication containing non-steroidal anti-inflammatory drugs (also known as NSAIDs), for example, indomethacin.
  • Oral hypoglycemic agents
  • Medications for the treatment of depression
  • Medications to reduce blood cholesterol levels (clofibrate).

Taking PRESINEX 0.1 mg tablets with food and drinks:

PRESINEX 0.1 mg tablets can be taken before or during meals with a glass of water.

Pregnancy and breastfeeding:

Consult your doctor or pharmacist before using any medication. During pregnancy, Presinex 0.1 mg tablets should be administered with caution.

Children:

Presinex 0.1 mg tablets are indicated in children over 5 years of age.

Driving and using machines:

Presinex 0.1 mg tablets have no effects that may affect the ability to drive and use machinery.

Important information about some of the ingredients of PRESINEX 0.1 mg tablets

This medication contains lactose. If your doctor has told you that you have an intolerance to certain sugars, consult with them before taking this medication.

3. HOW TO TAKE PRESINEX 0.1 mg tablets

Always take Presinex 0.1 mg tablets exactly as your doctor has told you. Check with them if you are unsure.

Central diabetes insipidus

Your doctor will indicate the most suitable individual dose. Generally, a dose of 0.1 mg to 1.2 mg per day is used. Therefore, in most cases, a treatment program of 1 tablet of Presinex 0.1 mg three times a day would be sufficient. To facilitate swallowing, the tablet can be broken before administration. Both parts should be taken.

Depending on the result, your doctor may adjust the treatment program.

If symptoms of water retention/hyponatremia appear, treatment should be interrupted and the dose adjusted again.

Primary nocturnal enuresis

In the case of using Presinex 0.1 mg tablets for the treatment of urinary incontinence, the full dose should be taken before going to bed.

Your doctor will determine the suitable individual dose. The initial suitable dose is 0.2 mg at bedtime. The dose can be increased to 0.4 mg if the lower dose is not sufficiently active.

Fluid intake should be controlled.

If symptoms or signs of water retention and/or hyponatremia (headache, nausea/vomiting, weight gain, and in severe cases, convulsions) appear, treatment should be interrupted until the patient has recovered. Once treatment is restarted, fluid intake should be strictly controlled.

After 3 months of treatment, the need for continuation is assessed by interrupting it for at least 1 week.

If you take more PRESINEX 0.1 mg tablets than you should:

Consult your doctor or pharmacist immediately or the Toxicology Information Service, telephone: 91 562 04 20, indicating the medication and the amount used.

If you forget to take PRESINEX 0.1 mg tablets

If you forget to take your tablets, please consult your doctor or pharmacist for advice. Do not take a double dose to make up for the forgotten dose.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, Presinex 0.1 mg tablets can cause side effects, although not everybody gets them.

Frequent, between 1 and 10 patients in every 100 patients treated:headache, stomach pain, nausea

Very rare, less than 1 in every 10,000 patients treated:decreased sodium levels in the blood, emotional disorders in children, and occasionally allergic reactions on the skin or more severe generalized reactions.

Due to decreased sodium levels in the blood due to water retention as a consequence of treatment along with reduced fluid intake, headache, nausea, vomiting, decreased sodium, weight gain, and in severe cases, convulsions may occur.

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.

5. Storing PRESINEX 0.1 mg tablets

Keep out of the reach and sight of children.

No special storage conditions are required.

Expiry date:

Do not use PRESINEX 0.1 mg tablets after the expiry date stated on the carton.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. FURTHER INFORMATION

Composition of PRESINEX 0.1 mg tablets:

  • The active substance is desmopressin acetate. Each tablet contains 0.1 mg of desmopressin acetate, equivalent to 0.89 mg of desmopressin base.
  • The other ingredients (excipients) are: lactose monohydrate, corn starch, povidone 25, and magnesium stearate.

Appearance and packaging of the product:

PRESINEX 0.1 mg tablets are presented in the form of tablets. The tablets are round, white, and scored. The score line on the Presinex tablet makes it possible to break the tablet before ingestion to facilitate swallowing. Once the tablet is broken, both parts should be taken.

Each bottle of Presinex 0.1 mg contains 100 tablets.

Marketing authorization holder:

CANTABRIA PHARMA S.L

C/ Ribera del Loira, 46 edificio 2

-28042- Madrid

Manufacturer:

Kern Pharma, S.L.

Poligono Industrial Colón II

C/.Venus, 72 08228 Terrasa

Barcelona

This leaflet was approved in: February 2007.

Online doctors for PRESINEX 0.1 mg TABLETS

Discuss questions about PRESINEX 0.1 mg TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (63)
Doctor

Nuno Tavares Lopes

Family medicine 18 years exp.

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Camera Book a video appointment
€59
5.0 (17)
Doctor

Anastasiia Shalko

Family medicine 13 years exp.

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.

Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate
Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.

She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.

With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

Camera Book a video appointment
€50
5.0 (3)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
Camera Book a video appointment
€80
0.0 (0)
Doctor

Andreea Mateescu

Paediatrics 8 years exp.

Dr Andreea Mateescu is a board-certified paediatrician with 7 years of clinical experience. She graduated from Carol Davila University of Medicine and Pharmacy in Bucharest, Romania, and completed her paediatric residency at INSMC Alessandrescu-Rusescu. She also holds additional training in general ultrasound diagnostics.

Dr Mateescu focuses on providing high-quality, evidence-based medical care for children, with a strong emphasis on prevention, healthy development, and long-term wellbeing. She believes that clear, empathetic communication with both children and parents is essential for building trust and ensuring effective care.

Online consultations with Dr Mateescu are suitable for:

  • preventive check-ups and monitoring of growth and development;
  • vaccination planning, including personalised and catch-up schedules;
  • assessment of psychomotor, emotional, and physical development;
  • diagnosis and management of acute and chronic paediatric conditions;
  • nutritional guidance for infants and children, including formula selection when medically indicated;
  • care for children with complex or rare conditions;
  • practical guidance and ongoing support for parents.
Dr Mateescu works with patience, empathy, and professionalism, ensuring that each child receives attentive, individualised care. Her goal is to support healthy, balanced development while helping parents feel confident and well-informed at every stage of their child’s care.
Camera Book a video appointment
€60
0.0 (0)
Doctor

Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance.

His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation.

Patients commonly consult Dr Daniel Cichi for:

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
  • chest discomfort, palpitations, dizziness, fatigue, and blood pressure concerns;
  • digestive problems: abdominal pain, nausea, diarrhoea, constipation, reflux;
  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders;
  • review and interpretation of lab tests, imaging reports, and medical documents;
  • medication review and treatment adjustment;
  • medical advice while travelling or living abroad;
  • second opinions and guidance on whether in-person care is needed.
Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.
Camera Book a video appointment
€55

Frequently Asked Questions

Is a prescription required for PRESINEX 0.1 mg TABLETS?
PRESINEX 0.1 mg TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in PRESINEX 0.1 mg TABLETS?
The active ingredient in PRESINEX 0.1 mg TABLETS is desmopressin. This information helps identify medicines with the same composition but different brand names.
Who manufactures PRESINEX 0.1 mg TABLETS?
PRESINEX 0.1 mg TABLETS is manufactured by Cantabria Pharma S.L.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of PRESINEX 0.1 mg TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether PRESINEX 0.1 mg TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to PRESINEX 0.1 mg TABLETS?
Other medicines with the same active substance (desmopressin) include DESMIRIN 360 micrograms/ml ORAL SOLUTION, DESMOPRESSIN ARISTO 120 MICROGRAMS SUBLINGUAL TABLETS, DESMOPRESSIN ARISTO 240 MICROGRAMS SUBLINGUAL TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media