Vitaminum Pp 200 mg

Package Leaflet: Information for the User

VITAMINUM PP 50 POLFARMEX, 50 mg, tablets

VITAMINUM PP 200 POLFARMEX, 200 mg, tablets

Nicotinamide

Read the package leaflet carefully before taking the medicine, as it contains important information for the patient.

• Keep this leaflet, you may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
• If you experience any side effects, including those not listed in this leaflet, tell your doctor or pharmacist.

Table of Contents of the Leaflet:

• 1. What is Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex and what is it used for
• 2. Important information before taking Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex
• 3. How to take Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex
• 4. Possible side effects
• 5. How to store Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex
• 6. Contents of the pack and other information

1. What is Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex and what is it used for

it is used for
Vitamin PP belongs to the group of vitamin B. It participates in the transfer of hydrogen and electrons in cellular respiration, glycolysis, and lipid biosynthesis processes.
Vitamin PP plays an important role in carbohydrate, fat, protein, purine and pyrimidine metabolism, as well as in the synthesis of high-energy compounds. Together with vitamin C and methionine, it accelerates the regeneration of visual purple. It stimulates liver and pancreas function, increases gastric juice secretion, enhances intestinal peristalsis, and plays an important role in skin, muscle, peripheral and central nervous system metabolism. After oral administration, vitamin PP is well absorbed from the gastrointestinal tract.
Vitamin PP is excreted in the urine, mainly in the form of N-methyl derivatives; only a small amount is excreted unchanged.
Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex is indicated for use:

• in the prevention and treatment of vitamin PP deficiency states.

Due to the frequent co-occurrence of deficiencies of many vitamins from group B and proteins, it is also recommended to administer other vitamins from group B in therapeutic doses and to use a high-protein diet.

2. Important information before taking Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex

200 Polfarmex

When not to take Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex:

• if the patient is allergic to vitamin PP or any of the other ingredients of this medicine (listed in section 6);
• if the patient has acute liver failure;
• if the patient has active gastric or duodenal ulcer disease;
• if the patient has gout.

Warnings and precautions

Before starting to take Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex, consult a doctor or pharmacist.
Particular caution should be exercised when using Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex in patients:

• with diabetes;
• who have had: jaundice, gastrointestinal ulcer disease, gout in the past. In the case of long-term use of high doses, periodic monitoring of liver function, uric acid concentration, and blood glucose concentration is recommended in patients with diabetes. Consult a doctor, even if the above warnings refer to past situations.

Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex and other medicines

Tell your doctor or pharmacist about all medicines you are taking or have recently taken, as well as any medicines you plan to take.
Vitamin PP increases the risk of myopathy (muscle damage) when used with cholesterol-lowering medicines from the statin group (simvastatin, pravastatin, and others).

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to have a child, consult a doctor or pharmacist before taking this medicine.

Driving and using machines

The medicine does not affect the ability to drive and use machines.

Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex contains lactose

If you have been diagnosed with an intolerance to some sugars, consult a doctor before taking the medicine.

3. How to take Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex

Take this medicine always as directed by your doctor. If you are unsure, consult a doctor or pharmacist.

Vitaminum PP 50 Polfarmex, 50 mg

If symptoms indicate a slight deficiency of vitamin PP, or if the patient's diet is poor in vitamin PP for various reasons, 1 to 2 tablets are usually given preventively per day.

Vitaminum PP 200 Polfarmex, 200 mg

For therapeutic purposes, depending on the degree of deficiency, 2 to 3 tablets per day, exceptionally up to 5 tablets per day in divided doses.
Swallow the tablet with water. To avoid or reduce irritation of the mucous membrane of the gastrointestinal tract, take after a meal.
The doctor may determine an individual dose depending on the patient's condition and the expected duration of treatment.

Taking a higher dose of Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex than recommended

Polfarmex

Overdose symptoms of vitamin PP may include headaches, tingling, itching of the head, ringing in the ears, feeling of indigestion, occasionally jaundice, heart rhythm disturbances. Vitamin PP overdose is associated with a risk of liver damage.
Consult a doctor immediately.

Missing a dose of Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex

Do not take a double dose to make up for a missed dose.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
The medicine is usually well tolerated.
Very rarely (in less than 1 in 10,000 people) redness of the skin, facial flushing, urticaria, and rash have been observed.
When taking high doses of the medicine (3 to 6 g per day), the following may occur: headaches and dizziness, vision disturbances, nausea, vomiting, diarrhea, increased uric acid or glucose concentration in the blood.
Cases of liver damage have been reported during long-term use or use of doses above 3 g/day.

Reporting side effects

If you experience any side effects, including those not listed in this leaflet, tell your doctor or pharmacist. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products
Al. Jerozolimskie 181C
02-222 Warsaw
Phone: (22) 49 21 301
Fax: (22) 49 21 309
Website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help to gather more information on the safety of this medicine.

5. How to store Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex

Keep the medicine out of the sight and reach of children.
Do not use this medicine after the expiry date stated on the carton and blister after: "EXP". The expiry date refers to the last day of the month.
There are no special precautions for storage.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

What Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex contains

• The active substance of the medicine is nicotinamide. One tablet contains 50 mg or 200 mg of nicotinamide.
• The other ingredients are: corn starch, lactose monohydrate, povidone K-25, magnesium stearate.

What Vitaminum PP 50 Polfarmex/Vitaminum PP 200 Polfarmex looks like and contents of the pack

The pack contains 20 tablets in blisters.

Marketing authorization holder and manufacturer

Polfarmex S.A.
ul. Józefów 9
99-300 Kutno
Phone: 24 357 44 44

Date of last revision of the leaflet: