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Noqturina

Ask a doctor about a prescription for Noqturina

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Doctor

Anastasiia Shalko

Family medicine12 years of experience

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.

Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate
Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.

She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.

With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Noqturina

Package Leaflet: Information for the Patient

Noqturina, 25 micrograms, oral lyophilisate

Noqturina, 50 micrograms, oral lyophilisate

Desmopressin

Read the package leaflet carefully before taking the medicine, as it contains important information for you.

  • Keep this package leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, including any not listed in this package leaflet, please inform your doctor. See section 4.

Table of Contents of the Package Leaflet:

  • 1. What is Noqturina and what is it used for
  • 2. Important information before taking Noqturina
  • 3. How to take Noqturina
  • 4. Possible side effects
  • 5. How to store Noqturina
  • 6. Contents of the package and other information

1. What is Noqturina and what is it used for

Noqturina contains desmopressin, an antidiuretic agent that reduces urine production.
Noqturina is used to treat nocturia (the need to urinate frequently at night) caused by nocturnal polyuria (excessive urine production at night) in adults.

2. Important information before taking Noqturina

When not to take Noqturina

  • if you are allergic to desmopressin or any of the other ingredients of this medicine (listed in section 6);
  • if you have polydipsia (excessive thirst and increased fluid intake) or psychogenic polydipsia (excessive thirst and increased fluid intake due to psychological factors);
  • if you have heart failure (the heart is not able to pump enough blood);
  • if you have any diseases that require the use of diuretics;
  • if you have moderate or severe renal impairment;
  • if you have or have had hyponatremia (low sodium levels in the blood);
  • if you have SIADH (inappropriate secretion of antidiuretic hormone).

Warnings and precautions

Before starting treatment with Noqturina, discuss it with your doctor.
Your doctor will exercise caution in the following cases:

  • if you have severe urinary bladder disorders and difficulty urinating;
  • if you are 65 years of age or older, as your doctor will need to monitor your sodium levels (see section 3, "How to take Noqturina" below);
  • if you have low sodium levels in your blood;
  • if you have a condition that affects water and/or electrolyte balance;
  • if you have a condition that may worsen due to water and/or electrolyte imbalance;
  • if you develop an acute illness (such as a generalized infection, a disease with fever, gastroenteritis) during treatment, as your doctor may need to interrupt treatment with Noqturina;
  • if you have cystic fibrosis, coronary heart disease, hypertension, chronic kidney disease, or pre-eclampsia.

Fluid intake should be limited to a minimum from 1 hour before taking Noqturina to 8 hours after taking Noqturina. Treatment without concurrent fluid restriction may lead to excessive water retention and/or electrolyte imbalance, which may cause symptoms such as headache, nausea, vomiting, weight gain, or, in severe cases, seizures.

Noqturina and other medicines

Tell your doctor about all the medicines you are taking or have recently taken, as well as any medicines you plan to take.
In particular, inform your doctor if you are taking:

  • tricyclic antidepressants, used to treat depression (such as clomipramine, imipramine, desipramine);
  • selective serotonin reuptake inhibitors, used to treat depression or anxiety disorders (such as citalopram, paroxetine, sertraline);
  • chlorpromazine, an antipsychotic medication used to treat schizophrenia;
  • diuretics (such as thiazides or other types of diuretics);
  • carbamazepine, used to treat bipolar affective disorder and epilepsy;
  • antidiabetic medications used to treat type 2 diabetes (sulfonylureas), especially chlorpropamide;
  • nonsteroidal anti-inflammatory drugs used to treat pain and inflammation (such as acetylsalicylic acid and ibuprofen);
  • oxytocin, used during childbirth;
  • lithium, used to treat bipolar affective disorder;
  • loperamide, used to treat diarrhea.

Taking Noqturina with food and drink

Noqturina should not be taken with food, as it may reduce the therapeutic effect.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to have a child, consult your doctor before taking this medicine.
Your doctor will decide whether you can take this medicine while pregnant or breastfeeding.

Driving and using machines

Noqturina has no or negligible influence on the ability to drive and use machines.

3. How to take Noqturina

Always take this medicine exactly as your doctor has told you.
If you are unsure, ask your doctor.
The recommended dose is:

  • for women: 25 micrograms per day, 1 hour before bedtime, taken sublingually, without drinking water;
  • for men: 50 micrograms per day, 1 hour before bedtime, taken sublingually, without drinking water.

Noqturina should be placed under the tongue, where it dissolves without the need for water.

Instructions for taking the medicine

  • 1.Remove the entire end strip of the blister pack by tearing it off along the perforation, starting from the corner with the printed hand symbol.
  • 2.Tear off one unit dose from the blister pack along the perforation.
  • 3.Remove the foil from the torn unit dose, starting from the corner with the printed arrow and pulling the foil in the direction indicated by the arrow. Do not press the lyophilisate through the foil.
  • 4.Gently remove the lyophilisate from the unit dose. Place the lyophilisate under the tongue and let it dissolve. Do not chew or swallow the lyophilisate.
  • 5.If the lyophilisate breaks into more than two pieces during removal from the unit dose, do not take the broken pieces. Take a lyophilisate from another unit dose.
Blister pack with numbered and arrow-marked areas for tearing and opening

Fluid intake should be limited to a minimum from 1 hour before taking Noqturina to 8 hours after taking Noqturina. If you experience any of the following symptoms, stop treatment and consult your doctor: headache, nausea, vomiting, weight gain, or, in severe cases, seizures (see "Warnings and precautions" above). Your doctor may recommend resuming treatment. When resuming treatment, it is essential to strictly limit fluid intake. Additionally, your doctor will closely monitor your sodium levels.

Taking Noqturina in elderly patients (65 years and older)

In patients 65 years of age or older, your doctor will need to monitor your sodium levels before starting treatment, during the first week of treatment (4-8 days after starting treatment), and again after about one month of treatment.

Taking Noqturina in patients with renal impairment

If you have moderate or severe renal impairment, do not take Noqturina.
Consult your doctor.

Taking Noqturina in patients with hepatic impairment

If you have hepatic impairment, consult your doctor before taking Noqturina.

Taking Noqturina in children and adolescents

This medicine is intended for use in adults only.

Taking more than the recommended dose of Noqturina

It is essential not to take more than the prescribed dose in any 24-hour period.
Pay particular attention to signs of water intoxication (hyponatremia), such as weight gain, headache, nausea, and, in severe cases, seizures.
If you take more than the recommended dose of Noqturina, consult your doctor.

Missing a dose of Noqturina

Do not take a double dose to make up for a missed dose. From the next day, continue taking the medicine as scheduled.

Stopping treatment with Noqturina

Treatment can only be stopped or discontinued in consultation with your doctor.
If you have any further questions about taking this medicine, consult your doctor.

4. Possible side effects

Like all medicines, Noqturina can cause side effects, although not everybody gets them.
Drinking excessive amounts of fluid may lead to water accumulation, which can cause a serious condition and lead to seizures.
Stop taking the medicine and immediately inform your doctor or go to the emergency department if you experience one or more of the following symptoms:

  • severe or prolonged headache,
  • confusion,
  • unexplained weight gain,
  • nausea or vomiting.

Side effects include:
Very common:may affect more than 1 in 10 people:

  • dry mouth.

Common:may affect up to 1 in 10 people:

  • nausea, malaise, muscle weakness, and confusion due to low sodium levels in the blood (hyponatremia),
  • headache,
  • dizziness,
  • nausea,
  • diarrhea.

Uncommon:may affect up to 1 in 100 people:

  • constipation,
  • stomach problems,
  • weakness,
  • peripheral edema (swelling of the limbs).

Reporting side effects

If you experience any side effects, including any not listed in this package leaflet, inform your doctor, pharmacist, or nurse. Side effects can be reported directly to the Department of Drug Safety, Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products:
Aleje Jerozolimskie 181C, 02-222 Warsaw, Tel: +48 22 49 21 301, Fax: +48 22 49 21 309; website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help to gather more information on the safety of this medicine.

5. How to store Noqturina

Keep the medicine out of sight and reach of children.
There are no special storage instructions for the medicine.
Store in the original package to protect from moisture and light.
Use immediately after opening the unit dose blister with the lyophilisate.
Do not use this medicine after the expiry date stated on the packaging after the label EXP.
The expiry date refers to the last day of the month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines that are no longer needed. This will help protect the environment.

6. Contents of the package and other information

What Noqturina contains

  • The active substance is desmopressin in the form of desmopressin acetate. One oral lyophilisate contains 25 micrograms of desmopressin. One oral lyophilisate contains 50 micrograms of desmopressin.
  • The other ingredients are: gelatin, mannitol (E 421), and anhydrous citric acid.

What Noqturina looks like and contents of the package

Noqturina 25 micrograms:
White, round lyophilisate tablet with a diameter of about 12 mm, marked with 25 on one side.
Noqturina 50 micrograms:
White, round lyophilisate tablet with a diameter of about 12 mm, marked with 50 on one side.
Blisters in a cardboard box. One blister, divisible into single doses, contains 10 oral lyophilisates.
Package sizes:
10x1, 30x1, 90x1, or 100x1 oral lyophilisates.
Not all package sizes may be marketed.

Marketing authorization holder and importer

Marketing authorization holder:
Ferring GmbH
Wittland 11
D-24109 Kiel
Germany
Importer:
Ferring GmbH
Wittland 11
D-24109 Kiel
Germany

This medicinal product is authorized in the Member States of the European Economic Area under the following names:

Austria
Nocdurna 25/50 microgram – Lyophilisate for oral use
Belgium
Nocdurna 25/50 microgram lyophilisate for oral use
Bulgaria
Нокдурна 25/50 микрограма перорален лиофилизат
Croatia
Nocdurna 25/50 microgram oral lyophilisate
Cyprus
Nocdurna
Denmark
Nocdurna
Estonia
Nokdirna
Finland
Nocdurna
France
Nocdurna 25/50 micrograms, lyophilisate oral
Greece
Nocdurna Δισκίο λυοφιλοποιημένο, από του στόματος 25mcgΠAB (Γνωστή δραστική)
Nocdurna Δισκίο λυοφιλοποιημένο, από του στόματος 50mcgΠAB (Γνωστή δραστική)
Netherlands
Nocdurna 25/50 microgram
Ireland
Noqturina 25/50 microgram oral lyophilisate
Iceland
Nocdurna
Liechtenstein
Nocdurna 25/50 microgram – Lyophilisate for oral use
Lithuania
Nokdirna
Luxembourg
Nocdurna 25 mcg lyophilisate oral/50 microgram oral lyophilisate
Latvia
Nokdirna 25/50 mikrogrami liofilizāts iekšķīgai lietošanai
Malta
Noqturina 25/50 microgram oral lyophilisate
Germany
Nocdurna
Norway
Nocdurna
Poland
Noqturina
Portugal
Nocdurna
Czech Republic
Nocdurna
Romania
Nocdurna 25/50 micrograme liofilizat oral
Slovakia
Nocdurna
Slovenia
Nocdurna 25/50 mikrogramov peroralni liofilizat
Sweden
Nocdurna
Hungary
Nocdurna
United Kingdom
Noqdirna 25/50 microgram oral lyophilisate

Date of last revision of the package leaflet: 04/2021

For more detailed information, please consult the representative of the marketing authorization holder.
Ferring Pharmaceuticals Poland Sp. z o.o.
Szamocka 8
01-748 Warsaw
Tel.: +48 22 246 06 80, Fax: +48 22 246 06 81

Alternatives to Noqturina in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Noqturina in Ukraine

Dosage form: solução, 20 UI/ml em ampolas de 1 ml ou 2 ml
Active substance: vasopressin (argipressin)
Manufacturer: AT "Farmak
Prescription required

Alternative to Noqturina in Espanha

Dosage form: PERFURAÇÃO INJETÁVEL, 20 UI/ml
Active substance: vasopressin (argipressin)
Prescription required
Dosage form: INJETÁVEL, 0,12 mg/ml
Active substance: terlipressin
Prescription required
Dosage form: INJETÁVEL, 1 mg
Active substance: terlipressin
Prescription required
Dosage form: INJETÁVEL, 0.2 mg/ml
Active substance: terlipressin
Manufacturer: Ever Valinject Gmbh
Prescription required
Dosage form: COMPRIMIDO ORODISPERSÍVEL/LIOTAB, 60 microgramas de acetato de desmopressina
Active substance: desmopressin
Manufacturer: Ferring S.A.
Prescription required
Dosage form: COMPRIMIDO ORODISPERSÍVEL/LIOTAB, 240 microgramas de acetato de desmopressina
Active substance: desmopressin
Manufacturer: Ferring S.A.
Prescription required

Online doctors for Noqturina

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Noqturina – subject to medical assessment and local rules.

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Dr. Duarte Meneses is a licensed family medicine and general practice doctor based in Portugal, with additional expertise in occupational health. He provides online consultations for adults, offering medical support for both acute symptoms and chronic health conditions.

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Dr. Meneses graduated from the University of Beira Interior and has years of experience working with diverse patient populations. He is fluent in Portuguese, English, Spanish, and French.

His approach is friendly, clear, and focused on delivering practical medical advice tailored to each patient’s needs.

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Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

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  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
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Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.

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With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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  • Help interpreting test results and lab reports
  • Preventive check-ups and advice on healthy lifestyle habits

Dr Kovalenko combines evidence-based practice with a respectful, patient-centred approach. She takes time to explain, listens attentively, and helps each person make confident, informed decisions about their health.

CameraBook a video appointment
€55
December 2009:00
December 2009:50
December 2010:15
December 2010:40
December 2011:05
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