Bg pattern

PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

Plerixafor Seacross 20 mg/ml Solution for InjectionEFG

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • If you get any side effects, talk to your doctor or pharmacist, even if you have read it in this leaflet. See section 4.

Contents of the pack

  1. What is Plerixafor Seacross and what is it used for
  2. What you need to know before you use Plerixafor Seacross
  3. How to use Plerixafor Seacross
  4. Possible side effects
  5. Storage of Plerixafor Seacross
  6. Contents of the pack and other information

1. What is Plerixafor Seacross and what is it used for

Plerixafor Seacross contains the active substance plerixafor which blocks a protein on the surface of hematopoietic stem cells. This protein "fixes" the stem cells to the bone marrow. Plerixafor improves the release of stem cells into the bloodstream (mobilization). The stem cells can be collected with a machine that separates the components of the blood (apheresis machine), then frozen and stored until transplantation.

If mobilization is poor, plerixafor is given to help collect stem cells from the patient's blood for collection, storage, and re-infusion (transplantation),

  • In adult patients with lymphoma (a cancer of white blood cells) or multiple myeloma (a cancer that affects the plasma cells of the bone marrow).
  • In children from 1 to less than 18 years with lymphoma or solid tumors.
Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Plerixafor Seacross

Do not use Plerixafor Seacross

  • if you are allergic to plerixafor or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Talk to your doctor before you start using plerixafor.

Tell your doctor:

  • if you have or have had any heart problems.
  • if you have kidney problems. Your doctor may adjust your dose.
  • if you have a high number of white blood cells.
  • if you have a low number of platelets.
  • if you have a history of feeling faint or dizzy while standing or sitting, or if you have fainted after injections.

Your doctor may perform blood tests periodicallyto check the number of blood cells.

Plerixafor is not recommended for the mobilization of stem cells if you have leukemia (a cancer of the blood or bone marrow).

Other medicines and Plerixafor Seacross

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

Pregnancy and breastfeeding

You should not use plerixafor if you are pregnant, as there are no data on the effects of plerixafor in pregnant women. It is important that you inform your doctor if you are pregnant, think you may be pregnant, or plan to become pregnant. The use of contraceptive methods is recommended if you are of childbearing age.

You should not breastfeed if you are using this medicine, as it is not known whether plerixafor passes into breast milk.

Driving and using machines

Plerixafor may cause dizziness and fatigue. Therefore, you should avoid driving if you feel dizzy, tired, or unwell.

Plerixafor Seacross contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per dose, which is essentially "sodium-free".

3. How to use Plerixafor Seacross

Your doctor or nurse will inject the medicine into you.

First, you will receive G-CSF and then you will be given Plerixafor Seacross

Mobilization will start by giving you another medicine called G-CSF (granulocyte colony-stimulating factor). G-CSF will help plerixafor work properly in your body. If you want more information about G-CSF, ask your doctor and read the corresponding package leaflet.

How much Plerixafor Seacross is given?

The recommended dose in adults is 20 mg (fixed dose) or 0.24 mg/kg body weight/day.

The recommended dose in children, from 1 to less than 18 years, is 0.24 mg/kg body weight/day.

Your dose will depend on your body weight, which must be measured the week before you receive the first dose. If you have moderate or severe kidney problems, your doctor may reduce the dose.

How is Plerixafor Seacross given?

Plerixafor is given by subcutaneous injection (under the skin).

When is Plerixafor Seacross given for the first time?

You will receive the first dose between 6 and 11 hours before apheresis (collection of stem cells from your blood).

How long will the administration of Plerixafor Seacross last?

Treatment lasts from 2 to 4 consecutive days (in some cases up to 7 days), until enough stem cells have been collected for transplantation. In some cases, it is not possible to collect enough stem cells, so the collection attempt will be interrupted.

If you have any further questions on the use of this medicine, ask your doctor, pharmacist, or nurse.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Tell your doctor immediately if

  • after receiving plerixafor, you have a skin rash, swelling around the eyes, difficulty breathing, or lack of oxygen, feeling dizzy while standing or sitting, feeling faint, or fainting.
  • you feel pain in the upper left part of your abdomen (stomach) or in your left shoulder.

Very common side effects(may affect more than 1 in 10 people)

  • diarrhea, nausea, redness, or irritation at the injection site.
  • low red blood cell count in laboratory tests (anemia in children).

Common side effects(may affect up to 1 in 10 people)

  • headache.
  • dizziness, feeling tired or unwell.
  • difficulty sleeping.
  • flatulence, constipation, indigestion, vomiting.
  • stomach symptoms such as pain, swelling, or discomfort.
  • dry mouth, numbness around the mouth.
  • sweating, generalized redness of the skin, joint pain, muscle and bone pain.

Uncommon side effects(may affect up to 1 in 100 people)

  • allergic reactions such as skin rash, swelling around the eyes, difficulty breathing.
  • anaphylactic reactions, including anaphylactic shock.
  • disturbed dreams, nightmares.

In rare cases, gastrointestinal side effects can be severe (diarrhea, vomiting, stomach pain, and nausea).

Myocardial infarction

In clinical trials, with low frequency, patients with risk factors for myocardial infarction had a myocardial infarction after administration of plerixafor and G-CSF. Tell your doctor immediately if you have chest discomfort.

Numbness and tingling

Numbness and tingling are common in patients receiving cancer treatment. About one in five patients experience them. However, these effects do not seem to occur more frequently when using plerixafor.

You may also have an increased number of white blood cells in your blood tests (leukocytosis).

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if it is possible side effects that are not listed in this leaflet. You can also report side effects directly through the Spanish Medicines and Healthcare Products Agency (AEMPS) website: www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Plerixafor Seacross

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton and vial after "EXP". The expiry date is the last day of the month shown.

This medicine does not require any special storage conditions.

Once the vial is opened, this medicine must be used immediately.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

What Plerixafor Seacross contains

  • The active substance is plerixafor. Each ml of solution for injection contains 20 mg of plerixafor. Each vial contains 24 mg of plerixafor in 1.2 ml of solution.
  • The other ingredients are sodium chloride, hydrochloric acid, and sodium hydroxide to adjust the pH, and water for injections.

Appearance and pack contents

Plerixafor Seacross is supplied as a clear, colorless solution for injection in a glass vial with a rubber stopper and an aluminum seal with a plastic cap. Each vial contains 1.2 ml of solution.

Each pack contains 1 vial.

Marketing authorization holder and manufacturer

Seacross Pharma (Europe) Limited

POD 13, The Old Station House

15A Main Street, Blackrock

Dublin, A94 T8P8

Ireland

Local representative

Pharmavic Ibérica, S.L.

C/ Compositor Lehmberg Ruiz

6 Edificio Ibiza, Oficina 7

29007 Málaga, (Spain)

Tel: 676295501

This medicine is authorized in the Member States of the European Economic Area under the following names:

Czech Republic

Pleforbil

Germany

Plerixafor Seacross 20 mg/ml Injektionslösung

Denmark

Plerixafor Seacross

Estonia

Plerixafor Auxilia

Spain

Plerixafor Seacross 20 mg/ml solution for injection

Finland

Plerixafor Seacross 20 mg/ml injektioneste, liuos

France

PLERIXAFOR SEACROSS 20 mg/ml, solution injectable

Croatia

Pleriksafor Onkogen 20 mg/ml otopina za injekciju

Hungary

Plerixafor Onkogen

Ireland

Plerixafor Seacross 20 mg/ml Solution for Injection

Italy

Plerixafor Seacross

Lithuania

Plerixafor Auxilia 20 mg/ml injekcinis tirpalas

Netherlands

Plerixafor Seacross 20 mg/ml oplossing voor injectie

Norway

Plerixafor Seacross

Poland

Plerixafor Biofar

Portugal

Plerixafor Seacross

Romania

Plerixafor Onkogen 20 mg/ml solutie injectabila

Sweden

Plerixafor Seacross

Slovenia

Pleriksafor Onkogen 20 mg/ml raztopina za injiciranje

Slovakia

Plerixafor Onkogen 20 mg/ml injekcný roztok

Date of last revision of this leaflet:June2023

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Healthcare Products (AEMPS) (http://www.aemps.gob.es/).

-----------------------------------------------------------------------------------------------------------------

This information is intended only for healthcare professionals:

Consult the summary of product characteristics for more information.

Online doctors for PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION

Discuss questions about PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (29)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
Camera Book a video appointment
€60
5.0 (29)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

Camera Book a video appointment
€60
5.0 (2)
Doctor

Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

Camera Book a video appointment
€55
5.0 (2)
Doctor

Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

Camera Book a video appointment
€55

Frequently Asked Questions

Is a prescription required for PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION?
PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION?
The active ingredient in PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION is plerixafor. This information helps identify medicines with the same composition but different brand names.
Who manufactures PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION?
PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION is manufactured by Seacross Pharma (Europe) Limited. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to PLERIXAFOR SEACROSS 20 mg/ml INJECTABLE SOLUTION?
Other medicines with the same active substance (plerixafor) include MOZOBIL 20 mg/ml INJECTABLE SOLUTION, PLERIXAFOR ACCORD 20 mg/ml INJECTABLE SOLUTION, PLERIXAFOR EUGIA 20 mg/ml INJECTABLE SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media