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OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES

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About the medicine

How to use OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the Patient

Osvical D 600 mg/400 UIeffervescent granule

Calcium, pidolate/Cholecalciferol (Vitamin D3)

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What Osvical D is and what it is used for
  2. What you need to know before you take Osvical D
  3. How to take Osvical D
  4. Possible side effects
  5. Storage of Osvical D
  6. Contents of the pack and further information

1. What Osvical D is and what it is used for

Osvical D is a calcium and vitamin D supplement.

Osvical D is used:

  • To prevent and treat calcium and vitamin D deficiency states in elderly people.
  • For the intake of vitamin D and calcium as complementary therapy for osteoporosis (fragile bones).
Doctor consultation

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2. What you need to know before you take Osvical D

Do not take Osvical D

  • if you are allergic to the active substances or any of the other ingredients of this medicine (listed in section 6).
  • if you have high levels of calcium in the blood (hypercalcaemia),
  • if you excrete too much calcium in the urine (hypercalciuria),
  • if you have overactivity of the parathyroid glands (hyperparathyroidism),
  • if you have bone marrow cancer (myeloma),
  • if you have cancer that has affected your bones (bone metastases),
  • if you have limited mobility of the limbs (prolonged immobilization) accompanied by hypercalcaemia and/or hypercalciuria,
  • if you have kidney stones (nephrolithiasis),
  • if you have an excess of vitamin D (hypervitaminosis D),
  • if you have severe kidney problems,
  • if you are under 18 years of age.

Warnings and precautions

Consult your doctor or pharmacist before starting to take Osvical D, especially if you are affected by any of the following:

  • Prolonged treatment

During prolonged treatment, calcium levels in blood and urine and kidney function should be monitored periodically. This is especially important if you have a tendency to develop kidney stones. Depending on blood levels, your doctor may reduce the dose or stop treatment.

  • If you are receiving simultaneous treatment with cardiac glycosides or thiazide diuretics (medicines that increase urine excretion) for heart problems.

In this case, calcium levels in blood and urine and kidney function should be monitored periodically, especially if you are an elderly patient. Depending on blood levels, your doctor may reduce the dose or stop treatment.

  • Kidney problems

If you have kidney problems, you should take this medicine with special care. Especially if you are receiving other medicines that contain aluminium, since the citric acid present in this medicine can increase aluminium absorption. Your calcium levels in blood and urine should be monitored. If you have severe kidney problems, use other forms of vitamin D that are not cholecalciferol.

  • Taking additional calcium and vitamin D supplements

Medical supervision is required and your doctor will require frequent monitoring of calcium levels in blood and urine.

  • Sarcoidosis (an immune disorder that can affect the liver, lungs, skin, or lymph nodes).

Be careful when taking this medicine if you have sarcoidosis. There is a risk that the effect of this medicine may become too strong, which can lead to an overdose of calcium in the body. Calcium levels in blood and urine should be monitored.

  • Immobility and osteoporosis

In these cases, this medicine should be used with special care, as it may increase calcium levels in the blood.

Children and adolescents

This medicine is not indicated for use in children or adolescents under 18 years of age (see "Do not take Osvical D").

Osvical D and other medicines

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

  • In case of simultaneous treatment with digitalis glycosides (cardiac glycosides derived from the digitalis plant), cardiac arrhythmias may occur. Therefore, strict medical monitoring is necessary, including an ECG and determination of calcium levels in the blood.
  • In case of simultaneous administration of thiazide diuretics (also known as medicines to increase urine excretion), calcium levels in the blood should be monitored periodically, as thiazides reduce calcium excretion in the urine.
  • The absorption and, therefore, the efficacy of certain antibiotics (called tetracyclines) decrease with simultaneous administration of Osvical D. These medicines should be taken at least 2 hours before or 4 to 6 hours after this medicine.
  • Additionally, other medicines such as sodium fluoride (used to strengthen tooth enamel or treat osteoporosis) and bisphosphonates (used to treat osteoporosis) are affected by interactions. Therefore, these medicines should be taken at least 3 hours before Osvical D.
  • The largest possible interval should be left between the administration of cholestyramine (a medicine to reduce high cholesterol levels) or laxatives such as liquid paraffin and this medicine, as otherwise, vitamin D may not be absorbed properly.
  • The simultaneous administration of Osvical D and phenytoin (a medicine for the treatment of epilepsy) or barbiturates (hypnotics) may lead to a reduction in the effect of vitamin D.
  • The simultaneous administration of Osvical D and glucocorticoids (e.g., cortisone) may lead to a reduction in the effect of vitamin D and a reduction in calcium levels in the blood.
  • Additional calcium and vitamin D supplements should only be administered under medical supervision and frequent monitoring of calcium levels in blood and urine is required.
  • Calcium may reduce the effect of levothyroxine (used to treat thyroid deficiency). For this reason, levothyroxine should be taken at least 4 hours before or 4 hours after this medicine.
  • There may be a reduction in the effect of quinolone antibiotics if taken at the same time as calcium. Take quinolone antibiotics at least 2 hours before or 6 hours after taking this medicine.
  • Calcium salts may decrease the absorption of iron, zinc, and strontium ranelate. Consequently, iron, zinc, or strontium ranelate preparations should be taken at least two hours before or after Osvical D lemon flavor.
  • Orlistat (used for the treatment of obesity) may alter the absorption of fat-soluble vitamins, such as vitamin D3.

Taking Osvical D with food, drinks, and alcohol

You can take the medicine at any time, with or without food.

You should be aware that oxalic acid (present in spinach and rhubarb) and phytic acid (present in whole grains) can reduce the amount of calcium absorbed in the intestine. In the 2 hours before or after eating foods high in oxalic acid or phytic acid, patients should not take medicines containing calcium.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

If you are pregnant, you can take this medicine in case of calcium and vitamin D deficiency.

Do not exceed the daily dose of one sachet. During pregnancy, the total daily amount of calcium should not exceed 1,500 mg and the total daily amount of vitamin D3 should not exceed 600 IU (International Units).

Long-term overdose of calcium and vitamin D during pregnancy should be avoided, as it can cause high levels of calcium in the blood and may have a negative effect on the fetus.

This medicine can be used during breastfeeding. Since calcium and vitamin D pass into breast milk, consult your doctor before giving your child other products containing vitamin D.

Driving and using machines

There is no sufficient data on the effects of this medicine on the ability to drive and use machines. However, the influence seems unlikely.

Osvical D contains aspartame

This medicine contains 30 mg of aspartame in each sachet.

Aspartame is a source of phenylalanine that may be harmful in case of phenylketonuria (PKU), a rare genetic disorder in which phenylalanine accumulates because the body cannot eliminate it properly.

Osvical D contains orange yellow S

It can cause allergic reactions. It can cause asthma, especially in patients allergic to acetylsalicylic acid.

Osvical D contains sodium

Consult your doctor or pharmacist if you need to take 2 or more sachets daily for a prolonged period, especially if you have been advised to follow a low-salt (sodium) diet.

Osvical D contains glucose

This medicine contains glucose (from maltodextrin and dextrin). If your doctor has told you that you have an intolerance to some sugars, consult them before taking this medicine.

Osvical D contains sorbitol

This medicine contains 0.4 mg of sorbitol (E420) in each sachet, equivalent to 0.05 mg/g.

3. How to take Osvical D

Follow the instructions for administration of this medicine exactly as indicated by your doctor. If you are unsure, consult your doctor or pharmacist again.

Dose

Unless your doctor tells you otherwise, the recommended dose is:

Adults and elderly people: 1 to 2 sachets per day (corresponding to 600 or 1,200 mg of calcium and 400 or 800 IU (International Units) of vitamin D3).

Pregnant women can take only 1 sachet per day. Do not exceed the daily dose of 1 sachet.

Use in children and adolescents

The safety and efficacy of this medicine in children have not been established, so its use is not recommended in this age group.

Method of administration

Oral use.

Dissolve the contents of the sachet in a glass of tap water. Osvical D can be taken at any time, with or without food.

Duration of treatment

Osvical D should be taken as prolonged treatment. Talk to your doctor about the duration of your treatment with Osvical D (see also section 2 "Warnings and precautions").

If you take more Osvical D than you should

Overdose of Osvical D can cause symptoms such as nausea, vomiting, thirst or excessive thirst, increased urine production, decreased body fluids, or constipation.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, telephone 91 562 04 20, indicating the medicine and the amount ingested.

If you forget to take Osvical D

If you forget to take Osvical D, take it as soon as you remember. Do not take a double dose to make up for forgotten doses.

If you stop taking Osvical D

If you want to stop or suspend treatment, consult your doctor.

If you have any other questions about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

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Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Stop taking Osvical D and contact a doctor immediately if you experience any of the following serious side effects:

Very rare (may affect up to 1 in 10,000 people)

  • Allergic reaction.
  • Swelling of the face, lips, tongue, or throat with sudden difficulty breathing and severe skin rash.

Other side effects reported are:

Uncommon (may affect up to 1 in 100 people)

  • High levels of calcium in the blood (hypercalcaemia) or urine (hypercalciuria).

Rare (may affect up to 1 in 1,000 people)

  • Nausea, vomiting, diarrhea, abdominal pain, constipation, gas, bloating (abdominal distension).
  • Skin rash, itching, urticaria.
  • Allergy.

Very rare (may affect up to 1 in 10,000 people)

  • Milk-alkali syndrome (also called Burnett syndrome, which usually only occurs when excessive amounts of calcium have been ingested). The symptoms are urgent need to urinate frequently, headache, loss of appetite, nausea or vomiting, unusual tiredness or weakness, along with high levels of calcium in the blood and alterations in kidney function.

If you have kidney failure, there may be a risk of having high levels of phosphate in the blood, high levels of calcium in the kidneys, and kidney stones.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Osvical D

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date is the last day of the month stated.

Store below 30°C.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and further information

Composition of Osvical D

  • The active substances are calcium pidolate and cholecalciferol. Each sachet contains 4,500 mg of calcium pidolate (equivalent to 600 mg of calcium) and 4 mg of cholecalciferol (vitamin D3) (equivalent to 400 IU of vitamin D3).
  • The other ingredients are: aspartame (E951), sodium bicarbonate, anhydrous sodium carbonate, anhydrous citric acid, anhydrous sodium citrate, orange flavor (contains natural flavors, wheat maltodextrin, and pea dextrin), lemon flavor [contains natural flavors, mannitol (E421), D-glucono-1,5-lactone (E575), wheat maltodextrin and/or potato dextrin, and sorbitol (E420)], orange yellow S (E110), povidone 30.

Appearance and packaging

Orange-colored granule with orange flavor and aroma.

Osvical D is presented in sachet form, in packs of 60 sachets.

Marketing authorization holder and manufacturer

Laboratorios Alter, S.A.

C/ Mateo Inurria 30

28036 Madrid

Spain

Date of last revision of this leaflet:June 2018.

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/.

Online doctors for OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES

Discuss questions about OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

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Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

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Alina Tsurkan

Family medicine 13 years exp.

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Yevgen Yakovenko

General surgery 12 years exp.

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Frequently Asked Questions

Is a prescription required for OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES?
OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
How much does OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES cost in pharmacies?
The average pharmacy price for OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES is around 25.84 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES?
OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES is manufactured by Laboratorios Alter S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to OSVICAL D 600 MG/400 IU EFFERVSCENT GRANULES?
Other medicines with the same active substance () include ADIAVAL 1000 mg/880 IU CHEWABLE TABLETS, BONESIL D FLAS 1500 mg/400 IU ORALLY DISINTEGRATING TABLETS, CADELIUS D 600 MG/2000 IU ORALLY DISINTEGRATING TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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