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IRUXOL MONO OINTMENT

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use IRUXOL MONO OINTMENT

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Iruxol Mono Ointment

Read all of this leaflet carefully before you start using this medicine.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you, do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any of the side effects, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

Contents of the Package Leaflet

  1. What is Iruxol Mono Ointment and what is it used for
  2. Before using Iruxol Mono Ointment
  3. How to use Iruxol Mono Ointment
  4. Possible side effects
  5. Storage of Iruxol Mono Ointment
  6. Further information

1. What is Iruxol Mono Ointment and what is it used for

The active ingredients are proteolytic enzymes, which act on components of skin ulcers. It is used for the debridement (cleaning and removal) of necrotic (dead) tissue in skin ulcers.

Doctor consultation

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Discuss your symptoms and treatment with a doctor online.

2. Before using Iruxol Mono Ointment

Do not use Iruxol Mono Ointment

-If you are allergic (hypersensitive) to the active ingredients or to any of the other ingredients of this medicine.

Take special care with Iruxol Mono Ointment

-If you have an infection in the ulcer, you should consult your doctor, who will apply the appropriate treatment, preferably orally. There are antibiotics that cannot be used with this medicine in the same area (see section Use of other medicines).

-If you use some soaps or antiseptics with the ointment, it may eliminate the effect of this medicine (see section Use of other medicines).

-In case you are weakened, caution is required and you should consult your doctor due to the risk of infection spread.

-If after 14 days from the start of treatment, there is no reduction in dead tissue, you should consult your doctor, who will interrupt the treatment and replace it with another.

Use of other medicines

Tell your doctor or pharmacist if you are using or have recently used other medicines, including those obtained without a prescription.

The following products should not be used together with Iruxol Mono Ointment because they may reduce or suppress its activity:

-Locally applied antibiotics such as tyrothricin, gramicidin, and tetracyclines.

-Detergents, soaps, acidic solutions, or antiseptics such as hexachlorophene and those containing heavy metals (e.g., mercurochrome).

-Other enzymatic preparations.

The following products can be used together with Iruxol Mono Ointment:

  • Antibiotics such as neomycin-bacitracin-polymyxin B and framicetin.

-Sterile saline solution.

Pregnancy and breastfeeding

Consult your doctor or pharmacist before using any medicine.

There is not enough data on the use of this medicine in pregnant or breastfeeding women. As a precaution, do not use Iruxol Mono Ointment during pregnancy and breastfeeding, unless your doctor considers it clearly necessary considering the potential risks versus benefits.

Driving and using machines

The use of Iruxol Mono does not have any effect on driving or using machines.

3. How to use Iruxol Mono Ointment

Follow exactly the administration instructions of Iruxol Mono Ointment indicated by your doctor. Consult your doctor or pharmacist if you have any doubts.

Topical use. To pierce the sealed tube, press using the reverse of the cap.

The normal dose is:

Adults

Apply a layer of ointment approximately 2 mm thick once a day, directly on the area to be treated, slightly moistened, for example with physiological serum. It can also be applied on a sterile gauze or dressing that is placed on the ulcer. Sometimes it may be necessary to apply the ointment twice a day.

Strict aseptic (clean) conditions must be maintained. Before each application, the lesion should be gently cleaned with a gauze impregnated with physiological serum or another cleaning solution compatible with the ointment to remove dead tissue (see section Use of other medicines).

If there is no reduction in dead tissue after 14 days from the start of treatment, you should inform your doctor, who will interrupt the treatment and replace it with another debridement method.

Use in children: The safety and efficacy of Iruxol Mono Ointment in children have not been established, so it should not be used in them.

If you use more Iruxol Mono Ointment than you should

Due to the characteristics of this medicine, intended for topical use, it is not expected to produce an overdose.

In case of overdose or accidental ingestion, consult your doctor or pharmacist or go to a medical center, or call the Toxicology Information Service, phone: 91 562 04 20, indicating the medicine and the amount ingested.

If you forget to use Iruxol Mono Ointment

Do not use more ointment to make up for forgotten doses. If you have forgotten a dose, apply it as soon as possible and continue with your usual schedule.

If you interrupt the treatment with Iruxol Mono Ointment

Do not interrupt the treatment until your doctor indicates it, or otherwise, the desired results will not be obtained.

If you have any other doubts about the use of this product, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, Iruxol Mono Ointment can cause side effects, although not everybody gets them.

Side effects such as pain, itching, irritation, inflammation, or redness of the skin have been observed, which usually do not require the interruption of the treatment.

If you consider that any of the side effects you are suffering from is serious, or if you notice any side effect not mentioned in this leaflet, inform your doctor or pharmacist.

Reporting of side effects:

If you experience any side effects, consult your doctor or pharmacist, even if it is a possible side effect not listed in this leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Iruxol Mono Ointment

Keep out of the reach and sight of children.

Do not store above 25°C.

Do not use Iruxol Mono Ointment after the expiration date stated on the packaging after CAD. The expiration date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Further information

Composition of Iruxol Mono Ointment

  • The active ingredients are Clostridiopeptidase A (Collagenase) and other proteolytic enzymes.

1 g of ointment contains 1.2 UI of Clostridiopeptidase A (Collagenase) and 0.24 UI of other proteolytic enzymes.

  • The other ingredients are liquid paraffin and solid paraffin.

Appearance and packaging of the product

Iruxol Mono is presented as an ointment. The ointment is colorless or slightly brown. Each package contains 15 or 30 g of ointment in an aluminum tube.

Marketing authorization holder and manufacturer

Smith & Nephew GmbH

Friesenweg 30, 22763 Hamburg, Germany

Manufacturer

Nordmark Pharma GmbH

Pinnauallee 4, 25436 Uetersen, Germany.

You can request more information about this medicine by contacting the local representative of the marketing authorization holder:

Local representative

Smith & Nephew, S.A.U

Fructuós Gelabert, 2-4

08970 Sant Joan Despí Barcelona, Spain

Phone: +34 93 373 7301

Fax: +34 93 373 7453

This leaflet was approved in April 2018.

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.es/

Online doctors for IRUXOL MONO OINTMENT

Discuss questions about IRUXOL MONO OINTMENT, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
  •  Musculoskeletal system (MSK)
  •  Angiography
  •  Abdomen and pelvis
  •  Soft tissues

Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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5.0 (43)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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5.0 (37)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Doctor

Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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€55

Frequently Asked Questions

Is a prescription required for IRUXOL MONO OINTMENT?
IRUXOL MONO OINTMENT requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in IRUXOL MONO OINTMENT?
The active ingredient in IRUXOL MONO OINTMENT is collagenase, combinations. This information helps identify medicines with the same composition but different brand names.
How much does IRUXOL MONO OINTMENT cost in pharmacies?
The average pharmacy price for IRUXOL MONO OINTMENT is around 10.58 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures IRUXOL MONO OINTMENT?
IRUXOL MONO OINTMENT is manufactured by Smith & Nephew Gmbh. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of IRUXOL MONO OINTMENT online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether IRUXOL MONO OINTMENT is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to IRUXOL MONO OINTMENT?
Other medicines with the same active substance (collagenase, combinations) include IRUXOL NEO OINTMENT, NEXOBRID 2 g powder and gel for gel, NEXOBRID 5 g powder and gel for gel. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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