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HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION

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About the medicine

How to use HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Havrix 720 Junior, injectable suspension in a pre-filled syringe

Vaccine against hepatitis A (inactivated, adsorbed)

Read all of this leaflet carefully before you or your child starts receiving this vaccine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist, or nurse.
  • This vaccine has been prescribed to you or your child, do not pass it on to others.
  • If you or your child experience any side effects, talk to your doctor, pharmacist, or nurse, even if they are not listed in this leaflet. See section 4.

This leaflet has been written assuming that the person receiving the vaccine is reading it, although it can be administered to children and adolescents, so you may need to read it for your child.

Contents of the package leaflet

  1. What Havrix 720 Junior is and what it is used for
  2. What you need to know before starting to receive Havrix 720 Junior
  3. How Havrix 720 Junior is administered
  4. Possible side effects
  5. Storage of Havrix 720 Junior
  1. Contents of the pack and further information

1. What Havrix 720 Junior is and what it is used for

What Havrix 720 Junior is used for

Havrix 720 Junior is a vaccine used to protect children and adolescents from 1 year to 15 years of age inclusive against infection caused by the hepatitis A virus.

Havrix 720 Junior can also be administered to adolescents from 16 years to 18 years of age inclusive, if necessary.

What hepatitis A is

  • Hepatitis A is a liver disease caused by the hepatitis A virus.
  • The hepatitis A virus can be transmitted from person to person or through contact with contaminated water, food, and drinks.
  • The symptoms of hepatitis A vary from mild to severe and can include: fever, general malaise, loss of appetite, diarrhea, nausea, abdominal discomfort, dark-colored urine, and jaundice (yellowing of the eyes and skin). Most people recover completely, although sometimes the disease can be severe and require hospitalization, and in rare cases, it can cause acute liver failure.

How Havrix 720 Junior works

  • Havrix 720 Junior helps your body produce its own protection (antibodies) against the virus. These antibodies help protect you against the disease.
  • As with all vaccines, it may be that Havrix 720 Junior does not completely protect all vaccinated individuals.
Doctor consultation

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2. What you need to know before starting to receive Havrix 720 Junior

Havrix 720 Junior must not be administered if:

  • you are allergic to the active substance or any of the other components of this vaccine (listed in section 6) or to neomycin or formaldehyde,
  • you have already had an allergic reaction to any hepatitis A vaccine.

The signs of an allergic reaction may include: itchy skin rash, difficulty breathing, and swelling of the face or tongue.

Havrix 720 Junior must not be administered if any of the above applies to you. If you are not sure, consult your doctor, pharmacist, or nurse before receiving Havrix 720 Junior.

Warnings and precautions

Consult your doctor, pharmacist, or nurse before receiving Havrix 720 Junior if:

  • you have a severe infection with a high temperature (fever). The vaccine can be administered once you have recovered. A minor infection, such as a cold, should not be a problem, but consult your doctor first,
  • you have a weakened immune system due to diseases and/or treatments. Your doctor will determine if additional injections are needed,
  • you have bleeding problems or bruise easily.

Fainting can occur before or after any injection with a needle. Therefore, inform your doctor, pharmacist, or nurse if you have fainted with a previous injection.

Other medicines and Havrix 720 Junior

Tell your doctor, pharmacist, or nurse if you are using, have recently used, or might use any other vaccine or medicine.

Havrix 720 Junior can be administered at the same time as other vaccines and immunoglobulins. A different injection site should be used for each injection.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor, pharmacist, or nurse before receiving Havrix 720 Junior.

Driving and using machines

The influence of Havrix 720 Junior on the ability to drive and use machines is negligible.

Havrix 720 Junior contains phenylalanine, polysorbate 20, sodium, and potassium

This vaccine contains 0.083 mg of phenylalanine per dose.

Phenylalanine may be harmful in case of phenylketonuria (PKU), a rare genetic disease in which phenylalanine accumulates because the body is unable to eliminate it properly.

This vaccine contains 0.025 mg of polysorbate 20 per dose. Polysorbates can cause allergic reactions. Inform your doctor if you have any known allergy.

This medicinal product contains less than 1 mmol of sodium (23 mg) per dose; i.e., it is essentially "sodium-free".

This medicinal product contains potassium, less than 1 mmol (39 mg) per dose; i.e., it is essentially "potassium-free".

3. How Havrix 720 Junior is administered

How the vaccine is administered

  • Your doctor or nurse will administer Havrix 720 Junior by injection into a muscle, usually in the upper arm in children and adolescents.
  • In small children, the injection can be administered into the thigh muscle.
  • Havrix 720 Junior can be injected under the skin if you have thrombocytopenia or severe bleeding disorders.

How much is administered

  • You will receive 1 dose of Havrix 720 Junior (0.5 ml suspension) on the date agreed with your doctor or nurse.
  • A second dose (booster) is recommended to be administered between 6 and 12 months after the first dose, although it can be administered up to five years after the first dose, to ensure long-term protection.

If you receive more Havrix 720 Junior than you should

It is very unlikely that an overdose will occur because the vaccine is supplied in a single-dose vial or syringe and is administered by a doctor or nurse. Few cases of accidental administration have been reported, and the adverse effects reported were similar to those reported with normal administration of the vaccine (listed in section 4).

If you miss a dose of Havrix 720 Junior

Contact your doctor, who will decide if a dose is required and when to administer it.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this vaccine can cause side effects, although not everybody gets them.

Serious side effects

Tell your doctor immediately if you notice any of the following serious side effects; you may need urgent medical treatment:

  • allergic reactions: the signs may include local or generalized rashes that can cause itching or blisters, swelling of the eyes and face, difficulty breathing or swallowing, a sudden drop in blood pressure, and loss of consciousness.

These reactions can occur before you leave the doctor's office.

Tell your doctor immediately if you notice any of the serious side effects listed above.

The side effects that occurred during clinical trials with Havrix 720 Junior were the following:

Very common(these may occur in more than 1 in 10 doses of the vaccine):

  • irritability
  • pain and redness at the injection site

Common(these may occur in up to 1 in 10 doses of the vaccine):

  • loss of appetite
  • headache
  • drowsiness
  • nausea
  • feeling unwell
  • fever of 37.5°C or higher
  • swelling at the injection site

Uncommon(these may occur in up to 1 in 100 doses of vaccine):

  • runny or stuffy nose
  • vomiting
  • diarrhea
  • skin rash
  • hardening at the injection site

The side effects that occurred after marketing of Havrix 720 Junior were the following:

  • seizures or convulsions
  • inflammation of blood vessels that causes narrowing or blockage (vasculitis)
  • severe allergic reaction that causes swelling of the face, tongue, or throat that can cause difficulty swallowing or breathing
  • hives, red spots that often itch and start on the extremities and sometimes on the face and the rest of the body.
  • joint pain

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse, even if they are not listed in this leaflet. You can also report them directly through the Spanish Medicines Agency's website: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Havrix 720 Junior

Keep this vaccine out of the sight and reach of children.

Do not use this vaccine after the expiry date stated on the pack. The expiry date is the last day of the month stated.

Store in a refrigerator (between 2°C and 8°C).

Do not freeze.

Store in the original packaging to protect it from light.

Medicines should not be disposed of via wastewater or household waste. Return the packaging and any unused medicine to a pharmacy for proper disposal. By doing so, you will help protect the environment.

6. Contents of the pack and further information

Composition of Havrix 720 Junior

The active substance is the hepatitis A virus (inactivated) adsorbed onto aluminum hydroxide. Each 0.5 ml dose of the vaccine contains 720 ELISA units of the hepatitis A virus.

The other ingredients are amino acids for injection (containing phenylalanine), disodium phosphate, monopotassium phosphate, polysorbate 20 (E-432), potassium chloride, sodium chloride, and water for injections (see section 2).

Appearance of the product and pack contents

Injectable suspension.

Havrix 720 Junior is a turbid liquid.

Havrix 720 Junior is available in a pre-filled syringe with or without a needle; pack sizes of 1, 5, 10, and 25.

Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Marketing authorization holder:

GlaxoSmithKline, S.A.

P.T.M. C/ Severo Ochoa, 2

28760 Tres Cantos (Madrid)

Spain

Tel.: +34 900 202 700

[email protected]

Manufacturer:

GlaxoSmithKline Biologicals s.a.

Rue de l´Institut 89

B-1330 Rixensart

Belgium

or

SmithKline Beecham, S.A.

Carretera de Ajalvir, km.2,5

28806 Alcalá de Henares (Madrid)

Spain

This medicine is authorized in the Member States of the European Economic Area under the following names:

Austria

Havrix (Hepatitis A-Impfstoff) Junior 720 EI.U/0.5 ml

Belgium, Cyprus, Luxembourg

Havrix Junior 720

Bulgaria

HAVRIX 720 suspension for injection (Junior monodose)

??????? 720 ??????????? ????????? (???? ?? ????)

Czech Republic

Havrix Junior monodose

Denmark, Finland, Iceland, Norway

Havrix

Estonia

Havrix, 720 ELISA ühikut/ml süstesuspensioon

France

HAVRIX NOURRISSONS ET ENFANTS 720 U/0.5 ml

Germany

Havrix 720 Kinder

Greece, Italy

HAVRIX

Hungary

Havrix 720 Junior

Ireland

Havrix Junior Monodose

Latvia

Havrix 720 ELISA vienibas/0.5 ml suspensija injekcijam

Lithuania

Havrix 720 ELISA vienetu/0.5 ml injekcine suspensija

Malta

Havrix Junior Monodose Vaccine

Netherlands

Havrix Junior

Poland

HAVRIX 720 JUNIOR

Portugal

Havrix 720 Júnior

Romania

HAVRIX JUNIOR 720 VACCIN HEPATITIC A

Slovak Republic

HAVRIX 720 Junior monodose

Slovenia

HAVRIX 720 PAEDIATRIC

Spain

Havrix 720 Junior injectable suspension in a pre-filled syringe

Sweden

Havrix 720 ELISA U/0.5 ml

Date of last revision of this leaflet:03/2025

Other sources of information

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/.

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This information is intended only for healthcare professionals:

Havrix 720 Junior is a turbid liquid suspension. During storage, the contents may present a fine white deposit and a clear colorless supernatant.

Before administration, the vaccine should be inspected visually for any foreign particles and/or variation in physical appearance. Before using Havrix 720 Junior, the pre-filled syringe should be shaken well to obtain a slightly opaque white suspension. Discard the vaccine if the contents appear otherwise.

Instructions for the pre-filled syringe

Text that saysText that says with a line underneath and a small dot at the endLuer-lock adapter with threaded connection and open end for syringe or catheter attachmentText that says 'Plunger' in bold black letters on a white backgroundPre-filled syringe with medication showing retracted plunger and protective cap on the right end

Hold the syringe by the body, not by the plunger.

Unscrew the syringe cap by turning it counterclockwise.

Metal needle base with a sharpened end and a slightly textured cylindrical bodyHands holding an injection device with attached needle showing connection and disconnection arrows

To insert the needle, attach the base to the Luer-lock adapter and turn it one-quarter turn clockwise until it clicks.

Do not pull the plunger out of the syringe body. If this happens, do not administer the vaccine.

Disposal of waste

Disposal of unused medicinal products and all materials that have come into contact with them should be done in accordance with local regulations.

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Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

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Endocrinology – Diabetes, thyroid, metabolism:
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Gastroenterology – Digestive health:
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  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
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  • Lab test analysis, therapy adjustments, medication management.
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Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

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Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
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  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
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  • Chronic conditions: diabetes, thyroid disorders.
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Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
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Marta Reguero Capilla

Allergology 8 years exp.

Dr Marta Reguero Capilla is an allergist and immunologist who works with both adults and children. She specialises in the diagnosis, treatment, and ongoing management of allergic and immune-related conditions through online consultations.

In her practice, Dr Reguero Capilla helps patients understand the causes of their symptoms, review test results, and choose appropriate treatment or monitoring strategies. Her consultations are suitable both for first-time assessments and for follow-up care over time.

Patients commonly consult Dr Marta Reguero Capilla for:

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Dr Reguero Capilla works in a structured and attentive manner, explaining medical decisions clearly and helping patients make informed choices about their own health or their child’s care.

When clinically appropriate, she may provide recommendations for further tests or referrals that patients can use within Spanish medical networks, including Sanitas and DKV, in accordance with the terms and conditions of those services.

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Frequently Asked Questions

Is a prescription required for HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION?
HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION?
The active ingredient in HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION is hepatitis A, inactivated, whole virus. This information helps identify medicines with the same composition but different brand names.
How much does HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION cost in pharmacies?
The average pharmacy price for HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION is around 22.64 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION?
HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION is manufactured by Glaxosmithkline S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to HAVRIX 720 JUNIOR, PRE-FILLED SYRINGE SUSPENSION?
Other medicines with the same active substance (hepatitis A, inactivated, whole virus) include AVAXIM JUNIOR Injectable Suspension in Pre-filled Syringe, AVAXIM Injectable Suspension in Pre-filled Syringe, HAVRIX 1440 ADULT, PRE-FILLED SYRINGE SUSPENSION FOR INJECTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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