Bg pattern

FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

Fetcroja 1 g powder for concentrate for solution for infusion

cefiderocol

Read all of this leaflet carefully before you are given this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or nurse.
  • If you get any side effects, talk to your doctor or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Fetcroja and what is it used for
  2. What you need to know before you are given Fetcroja
  3. How to use Fetcroja
  4. Possible side effects
  5. Storage of Fetcroja
  6. Contents of the pack and other information

1. What is Fetcroja and what is it used for

Fetcroja contains the active substance cefiderocol. It is an antibiotic that belongs to a group of antibiotics called cephalosporins. Antibiotics help fight bacteria that cause infections.

Fetcroja is used in adults to treat infections caused by certain types of bacteria when other antibiotics cannot be used.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you are given Fetcroja

Do not use Fetcroja

  • if you are allergic to cefiderocolor to any of the other ingredients of this medicine (listed in section 6);
  • if you are allergic to other antibioticsknown as cephalosporins;
  • if you have had a severe allergic reaction to certain antibiotics,such as penicillins or carbapenems. This can include severe skin peeling; swelling of the hands, face, feet, lips, tongue or throat; or difficulty swallowing or breathing.
  • Tell your doctorif any of these points apply to you.

Warnings and precautions

Talk to your doctor or nurse before you are given Fetcroja:

  • if you have ever had an allergic reaction to other antibiotics.See also the previous section «Do not use Fetcroja»;
  • if you have kidney problems.Your doctor will adjust your dose to make sure you do not receive too much or too little medicine;
  • if you get diarrheaduring your treatment;
  • if you have ever had seizures.
  • Talk to your doctor or nursebefore you are given Fetcroja.

New infection

Although Fetcroja can combat certain bacteria, there is a possibility that you may get a different infection caused by another microorganism during or after treatment. Your doctor will closely monitor you for any new infection and give you another treatment if necessary.

Blood/laboratory tests

If you need to have any blood/laboratory tests, tell your doctor that you are taking Fetcroja, as you may get an abnormal result. With a test called «Coombs test», the presence of antibodies that can destroy red blood cells or that can be affected by your immune system's response to Fetcroja is sought. Fetcroja can also produce false positive results in urine tests with test strips (proteins in urine or diabetes markers).

Children and adolescents

Fetcroja must not be given to children and adolescents under 18 years of age, as it is not known if it is safe to use the medicine in these age groups.

Other medicines and Fetcroja

Tell your doctor or nurse if you are taking, have recently taken or might take any other medicines.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before you are given this medicine.

Driving and using machines

Fetcroja does not affect your ability to drive or use machines.

Fetcroja contains sodium

This medicine contains 7.64 mmol (176 mg) of sodium per vial. The daily dose is 2.1 g, just above the maximum daily intake of 2 g of sodium recommended by the WHO for an adult. Talk to your doctor before you are given Fetcroja if you are on a low-sodium diet.

3. How to use Fetcroja

Your doctor or nurse will give you this medicine by infusion (drip) into a vein over 3 hours, 3 times a day. The recommended dose is 2 g.

The number of days you will receive treatment with Fetcroja depends on the type of infection you have and how the infection is going.

If you feel pain at the site where Fetcroja is being administered to your vein, tell your doctor or nurse.

People with kidney problems

If you have kidney problems, talk to your doctor before you are given Fetcroja. Your doctor will adjust your dose of Fetcroja.

If you are given too much Fetcroja

A doctor or nurse will give you Fetcroja, so it is unlikely that you will be given the wrong dose. If you think you have been given too much Fetcroja, tell your doctor or nurse immediately.

If you miss a dose of Fetcroja

If you think you have missed a dose of Fetcroja, tell your doctor or nurse immediately.

If you have any other questions about the use of this medicine, ask your doctor or nurse.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Serious side effects

Tell your doctor immediately if you notice any of the following serious side effects, as you may need urgent medical treatment:

  • Severe allergic reaction: signs include sudden swelling of the lips, face, throat or tongue; a severe skin rash or other severe skin reactions; difficulty swallowing or breathing. This reaction can be life-threatening.
  • Diarrhea that gets worse or does not go away, or stools that contain blood or mucus. This can happen during treatment or after stopping treatment. If this happens, do not take medicines that slow down or stop bowel movements.
  • Tell your doctorimmediately if you notice any of the above serious side effects.

Other side effects

Tell your doctor or nurse if you notice any of the following side effects.

Common

(may affect up to 1 in 10 people)

  • Nausea or vomiting.
  • Swelling, redness and/or pain around the needle where the medicine is administered into a vein.
  • Fungal infections, e.g. candidiasis.
  • Increased levels of liver enzymes; seen in blood tests.
  • Cough.
  • Rash with small bumps.
  • Severe intestinal infection called Clostridioides difficilecolitis. Symptoms include watery diarrhea, abdominal pain, fever, etc.
  • Increased creatinine in blood.

Uncommon

(may affect up to 1 in 100 people)

  • Increased urea in blood.
  • Allergy to Fetcroja.

Frequency not known

(frequency cannot be estimated from the available data)

  • Decreased number of certain white blood cells (neutrophil granulocytes).
  • Discoloration of urine (chromaturia).

Reporting of side effects

If you experience any side effects, talk to your doctor or nurse, even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Medicines Agency website: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Fetcroja

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the label. The expiry date is the last day of the month stated.

Store the vials in a refrigerator (between 2°C and 8°C).

Store in the original packaging to protect from light.

6. Contents of the pack and other information

What Fetcroja contains

  • The active substance is cefiderocol sulfate tosylate, equivalent to 1 g of cefiderocol.
  • The other excipients are sucrose, sodium chloride, and sodium hydroxide.

Appearance and packaging

Fetcroja is a white to off-white powder for concentrate for solution for infusion in a vial. It is available in packs of 10 vials.

Marketing authorisation holder and manufacturer

Shionogi B.V.

Herengracht 464

1017CA Amsterdam

Netherlands

For further information about this medicine, contact the local representative of the marketing authorisation holder:

AT, BE, BG, CY, CZ, DK, EE, EL, FI, HR, HU, IE, IS, LT, LU, LV, MT, NL, NO, PL, PT, RO, SE, SI, SK

Shionogi B.V. Tel/Tel./ Te?./ Tlf./ Tél/ Puh/ Sími/ Τηλ:

+31 (0)20 703 8327

[email protected]

Germany

Shionogi GmbH

Tel: + 49 (0)30 2062980 66

[email protected]

Spain

Shionogi SLU

Tel: + 34 911 239 258

[email protected]

Italy

Shionogi Srl

Tel: + 39 06 94 805 118

[email protected]

France

Shionogi SAS

Tel: +33 (0) 186655806

[email protected]

Date of last revision of this leaflet: 01/2025

Other sources of information

Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu

--------------------------------------------------------------------------------------------------------------------

This information is intended only for healthcare professionals:

Each vial is for single use only.

The powder should be reconstituted with 10 ml of sodium chloride 9 mg/ml (0.9%) injection solution or 5% glucose injection solution, which is drawn from 100 ml bags that will be used to prepare the final infusion solution, and the vials should be gently shaken to dissolve the powder. The vials should be left to stand until the foam generated on the surface disappears (usually within 2 minutes). The final volume of the reconstituted solution in the vial will be approximately 11.2 ml (warning: the reconstituted solution must not be injected directly).

To prepare the required doses, the appropriate volume of reconstituted solution should be withdrawn from the vial according to the table below. Add the withdrawn volume to the infusion bag containing the remaining 100 ml of sodium chloride 9 mg/ml (0.9%) injection solution or 5% glucose injection solution, visually inspect the resulting solution with the diluted medicine in the infusion bag for particles or color change before use. Do not use solutions that have changed color or have visible particles.

Preparation of cefiderocol doses

Dose of

Number of vials of

Volume to be

Total volume of cefiderocol

cefiderocol

1 g of cefiderocol

withdrawn from the vials

solution needed for further dilution

to be reconstituted

in at least 100 ml of

sodium chloride 0.9% injection solution

or 5% glucose injection solution

2 g

2 vials

11.2 ml (complete contents) of both vials

22.4 ml

1.5 g

2 vials

11.2 ml (complete contents) of the first vial and 5.6 ml of the second vial

16.8 ml

1 g

1 vial

11.2 ml (complete contents)

11.2 ml

0.75 g

1 vial

8.4 ml

8.4 ml

Standard aseptic techniques should be followed to prepare and administer the solution.

This medicine should not be mixed with other medicines except for those mentioned above in this section. If it is not possible to avoid combined treatment with another medicine and Fetcroja, administration should not be in the same syringe or infusion solution. It is recommended to properly clean the intravenous lines between the administration of different medicines.

Disposal of unused medicine and all materials that have come into contact with it should be in accordance with local regulations.

Online doctors for FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION

Discuss questions about FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

0.0 (0)
Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Camera Book a video appointment
€58
5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

Camera Book a video appointment
€80
5.0 (1055)
Doctor

Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Camera Book a video appointment
€80
0.0 (0)
Doctor

Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

Camera Book a video appointment
€55

Frequently Asked Questions

Is a prescription required for FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION?
FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION?
The active ingredient in FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION is cefiderocol. This information helps identify medicines with the same composition but different brand names.
Who manufactures FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION?
FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION is manufactured by Shionogi B.V.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to FETCROJA 1 g POWDER FOR CONCENTRATE FOR PERFUSION SOLUTION?
Other medicines with the same active substance (cefiderocol) include CEFTAROLINA FOSAMILO QILU 600 mg POWDER FOR CONCENTRATE FOR INFUSION SOLUTION, ZERBAXA 1 g/0.5 g POWDER FOR CONCENTRATE FOR INFUSION SOLUTION, ZEVTERA 500 mg POWDER FOR CONCENTRATE FOR INFUSION SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media