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FEPARIL 10mg/g + 50mg/g GEL

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use FEPARIL 10mg/g + 50mg/g GEL

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Feparil 10mg/g + 50mg/g Gel

escin / diethylamine salicylate

Read the entire package leaflet carefully before starting to use this medication, as it contains important information for you.

Follow the administration instructions for the medication contained in this package leaflet or as indicated by your doctor or pharmacist.

  • Keep this package leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are side effects not listed in this package leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve after 5 days.

Contents of the Package Leaflet

  1. What is Feparil and what is it used for
  2. What you need to know before using Feparil
  3. How to use Feparil
  4. Possible side effects
  5. Storage of Feparil
  6. Package Contents and Additional Information

1. What is Feparil and what is it used for

This medication is indicated for the local symptomatic relief of superficial venous disorders, such as heaviness and tightness of the legs with varices in adults.

Also for the symptomatic relief of pain and superficial bruising caused by blows, bruises, sprains, and mild strains as a result of a twist in adults and children over 12 years of age.

You should consult a doctor if it worsens or does not improve after 5 days.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before using Feparil

Do not use Feparil

  • If you are allergic to escin, diethylamine salicylate, acetylsalicylic acid, or other non-steroidal anti-inflammatory drugs (NSAIDs), or to any of the other components of this medication (listed in section 6).
  • In skin conditions, such as dermatitis, eczema, or hives.
  • On mucous membranes, or on irritated, wounded, or radiated skin areas.

Warnings and Precautions

For external use only.

Use only on intact skin.

Avoid contact with the eyes.

Do not apply simultaneously to the same area as other topical medications.

Do not use for a prolonged period without medical supervision.

Children and Adolescents

Do not use in children under 12 years of age.

Other Medications and Feparil

Inform your doctor or pharmacist if you are using, have recently used, or may need to use any other medication.

No interactions with other medications are known. However, avoid simultaneous application with another topical preparation to avoid possible interference between active ingredients.

Using Feparil with Food, Drinks, and Alcohol

No effect has been described between the use of this medication and the consumption of food and drinks.

Pregnancy and Breastfeeding

Consult your doctor or pharmacist before using any medication.

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medication. The use of medications during pregnancy can be hazardous to the embryo or fetus and should be monitored by your doctor.

Driving and Using Machines

No effects of this medication on the ability to drive and use machines are expected.

Feparil contains fragrances with d-limonene, linalool, and farnesol.

D-limonene, linalool, and farnesol may cause allergic reactions.

3. How to Use Feparil

Follow the administration instructions for the medication contained in this package leaflet or as indicated by your doctor or pharmacist. If in doubt, ask your doctor or pharmacist.

Use exclusively on intact skin.

Adults and children over 12 years of age.

Apply a thin layer of gel one to three times a day to the affected area, performing a small massage to favor the absorption of the product. The use of an occlusive dressing is not recommended, but if necessary, it can be covered with a gauze.

The maximum daily dose is 20 g of gel, which is equivalent to approximately 1,000 mg of diethylamine salicylate.

Do not use the medication on large areas of skin.

If symptoms worsen or persist after 5 days, you should consult a doctor.

Wash your hands after each application to avoid unintentional contact with eyes and mucous membranes.

If You Use More Feparil Than You Should

In case of overdose or accidental ingestion, go to a medical center or consult the Toxicology Information Service, phone 915 62 04 20, indicating the medication and the amount ingested.

If You Forget to Use Feparil

Do not apply a double dose to make up for forgotten doses.

Wait for the next application and continue with the usual routine.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible Side Effects

Like all medications, this medication can cause side effects, although not everyone will experience them.

During the period of use of the combination of escin and diethylamine salicylate in gel, the following side effects have been observed, whose frequency could not be established with precision:

They are generally mild and infrequent.

Disorders of the skin and subcutaneous tissue: erythema (redness of the skin) may appear in the application area due to local irritation or because contact dermatitis has occurred. Both disappear completely when treatment is stopped.

Reporting Side Effects

If you experience any type of side effect, consult your doctor or pharmacist, even if it is a possible side effect not listed in this package leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medications: https://www.notificaRAM.es. By reporting side effects, you can contribute to providing more information on the safety of this medication.

5. Storage of Feparil

This medication does not require special storage conditions.

Keep this medication out of the sight and reach of children.

Do not use this medication after the expiration date (EXP.) that appears on the box and tube. The expiration date is the last day of the month indicated.

Medications should not be disposed of through wastewater or household waste. Ask your pharmacist how to dispose of the packaging and medications you no longer need. This will help protect the environment.

6. Package Contents and Additional Information

Composition of Feparil

  • The active ingredients are escin and diethylamine salicylate.
  • The other components are polyacrylic acid, macrogol-6-glycerol caprylocaprate, disodium edetate, tromethamine, isopropyl alcohol, purified water, lavender oil, and orange blossom oil.

Appearance of the Product and Package Contents

Feparil is a clear, colorless to light yellow gel with a lavender scent, presented in aluminum tubes containing a total of 40 or 100 g of gel.

Marketing Authorization Holder and Manufacturer

Marketing Authorization Holder

Cooper Consumer Health B.V.

Verrijn Stuartweg 60,

1112 AX Diemen,

Netherlands

Manufacturer

Madaus GmbH

Lutticher Strasse, 5

53842 Troisdorf

Germany

You can request more information about this medication by contacting the local representative of the marketing authorization holder:

Vemedia Pharma Hispania, S.A.

C/ Aragón, 182, 5th floor

08011 – Barcelona

Spain

Date of the Last Revision of this Package Leaflet:January 2024

Detailed information about this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es)

Online doctors for FEPARIL 10mg/g + 50mg/g GEL

Discuss questions about FEPARIL 10mg/g + 50mg/g GEL, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance. His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation. Patients commonly consult Dr Daniel Cichi for: 

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
  • chest discomfort, palpitations, dizziness, fatigue, and blood pressure concerns;
  • digestive problems: abdominal pain, nausea, diarrhoea, constipation, reflux;
  • sexually transmitted infections, erectile dysfunction;
  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders, weight loss, hair loss;
  • review and interpretation of lab tests, imaging reports, and medical documents;
  • medication review and treatment adjustment;
  • medical advice while travelling or living abroad;
  • second opinions and guidance on whether in-person care is needed.

Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.

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Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Doctor

Lisa Drigo

Paediatrics 34 years exp.

Dr Lisa Drigo is an experienced paediatrician based in Italy with over 30 years of clinical practice. She graduated from Università Cattolica del Sacro Cuore in Rome and has spent decades working within the Italian healthcare system, supporting children and families with both acute care and long-term prevention.

She is well familiar with Italian paediatric standards, including local vaccination schedules, preventive check-ups, growth monitoring, and everyday medical issues faced by families living in Italy. This makes her consultations especially valuable for parents who want guidance that aligns with local medical practice.

Her primary focus is paediatrics, with additional support in family medicine when a child’s health needs to be assessed in a broader family or preventive context.

Patients most often consult her for:

  • Acute infections in children (fever, cough, sore throat, runny nose).
  • Viral and bacterial illnesses, frequent colds.
  • Digestive symptoms such as abdominal pain, nausea, diarrhoea or constipation.
  • Monitoring of growth, weight, and developmental milestones.
  • Vaccination advice according to Italian schedules.
  • Allergic reactions, skin rashes, food sensitivities.
  • General health concerns and everyday questions from parents.
  • Preventive care, nutrition advice, and healthy lifestyle guidance.

Dr Drigo communicates in a clear, calm, and reassuring way, helping parents understand what is happening and what steps to take next. Online consultations allow families to receive reliable paediatric guidance aligned with Italian medical practice, without unnecessary stress or waiting.

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Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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€60
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Doctor

Sviatoslav Chekhun

Oncology 13 years exp.

Dr. Sviatoslav Chekhun is a medical oncologist with international clinical and research experience, specializing in modern medical oncology and a personalized approach to cancer treatment.

Currently (since 2025), he works as a Medical Oncologist at Institut Català d’Oncologia (Girona, Spain). Previously, he completed his residency in Medical Oncology and was involved in clinical research at Hospital Universitari Germans Trias i Pujol.

Dr. Chekhun has a strong academic and scientific background. He served as a lecturer in Internal Medicine at O.O. Bohomolets National Medical University and conducted research in experimental oncology at the R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology.

Earlier in his career, he worked as a medical oncologist at the Kyiv City Clinical Oncological Center and contributed to regulatory evaluation of medicinal products at the State Expert Center of the Ministry of Health of Ukraine.

When to consult Dr. Chekhun:

  •  for diagnosis or clarification of a cancer diagnosis
  •  to obtain a second opinion on an existing treatment plan 
  •  when you need a personalized treatment strategy 
  •  for interpretation of test results, CT, MRI, PET-CT, and biopsies 
  •  when choosing between treatment options (chemotherapy, targeted therapy, immunotherapy) 
  •  in case of doubts about treatment strategy or disease progression 

Consultation format

Dr. Chekhun provides online consultations, where you can receive:

  •  expert second opinion 
  •  detailed case review 
  •  recommendations based on current international treatment guidelines 
  •  personalized treatment and follow-up plan 

Important:
Prescription and monitoring of medications must be carried out by your treating physician in an in-person (offline) setting. An online consultation does not replace a face-to-face visit but helps you make more informed decisions about your treatment.

Dr. Sviatoslav Chekhun combines clinical practice, research, and international experience, enabling him to provide patients with modern, evidence-based approaches in oncology.

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Doctor

Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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€55
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Frequently Asked Questions

Is a prescription required for FEPARIL 10mg/g + 50mg/g GEL?
FEPARIL 10mg/g + 50mg/g GEL does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
Who manufactures FEPARIL 10mg/g + 50mg/g GEL?
FEPARIL 10mg/g + 50mg/g GEL is manufactured by Cooper Consumer Health B.V.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of FEPARIL 10mg/g + 50mg/g GEL online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether FEPARIL 10mg/g + 50mg/g GEL is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to FEPARIL 10mg/g + 50mg/g GEL?
Other medicines with the same active substance () include DOXIUM FUERTE 500 mg HARD CAPSULES, ETOXISCLEROL 10 mg/mL Injectable Solution, ETOXISCLEROL 20 mg/ml INJECTABLE SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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