Bg pattern

ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

Esmeron 10 mg/ml solution for injection and infusion

Rocuronium, bromide

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • If you experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.

Contents of the package leaflet

  1. What is Esmeron and what is it used for
  2. What you need to know before you use Esmeron
  3. How to use Esmeron
  4. Possible side effects
  5. Storage of Esmeron
  6. Contents of the pack and further information

1. What is Esmeron and what is it used for

Esmeron belongs to a group of medicines called muscle relaxants. Muscle relaxants are used in general anesthesia for surgical operations to relax the muscles completely. This makes the operation easier for the surgeon. Normally, nerves send messages to the muscles through impulses. Esmeron works by blocking these impulses, causing the muscles to relax. Since the muscles needed for breathing also relax, you will need help breathing (artificial respiration) during and after the operation until you can breathe on your own. The effect of the muscle relaxant is regularly monitored during the operation, and if necessary, more medication will be administered. The effects disappear at the end of the operation, and then you can start breathing on your own. Sometimes, another medication is given to speed up this process. Esmeron can also be used in the Intensive Care Unit to keep the muscles relaxed.

This medicine is for hospital use only.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Esmeron

Do not use Esmeron:

  • if you are allergic to rocuronium, bromide ions, or any of the other components of this medicine (listed in section 6).

Warnings and precautions

Your medical history may affect how Esmeron is administered to you.

Tell your anesthesiologist if you have had or currently have any of the following diseases:

  • allergy to muscle relaxants
  • kidney disease
  • heart disease
  • edema (fluid retention, for example, in the calves)
  • liver or bile duct disease, or liver function disorders
  • diseases that affect the nerves and muscles.

Also, inform your anesthesiologist if you have had:

  • a history of malignant hyperthermia (sudden fever with palpitations, rapid breathing, and muscle stiffness, pain, and/or weakness).

Certain medical conditions may affect how Esmeron works. For example, if you have any of these conditions, your anesthesiologist will take them into account when deciding the correct dose of Esmeron:

  • low potassium levels in the blood
  • high magnesium levels in the blood
  • low calcium levels in the blood
  • low protein levels in the blood
  • dehydration
  • too much acid in the blood
  • too much carbon dioxide in the blood
  • poor overall health
  • overweight
  • burns.

Children/elderly patients

Esmeron can be used in children and adolescents (from birth to 17 years) and elderly patients, but your anesthesiologist will evaluate your medical history first.

Using Esmeron with other medicines

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines.

Other medicines may affect the effects of Esmeron or vice versa. If you take (or think you might take) any of the following medicines, you should inform your doctor.

The following medicines may increasethe effect of Esmeron:

  • certain anesthetics
  • prolonged use of corticosteroids with Esmeron for a long time in the Intensive Care Unit (anti-inflammatory medications)
  • certain medications for bacterial infections (antibiotics)
  • certain medications for bipolar disorder (such as lithium)
  • certain medications for heart disease or high blood pressure (quinidine, calcium antagonists, beta-blockers)
  • certain medications for malaria (quinine)
  • medications that increase urine production, such as diuretics
  • magnesium salts
  • local anesthetics (lidocaine, bupivacaine)
  • use of medications for epilepsy during an operation (phenytoin).

The following medicines may decreasethe effect of Esmeron:

  • prolonged use of medications for epilepsy: phenytoin and carbamazepine
  • medications for pancreatitis, blood coagulation disorders, or acute blood loss (protease inhibitors: gabexate, ulinastatin).

The following medicines have a variable effecton Esmeron:

  • other muscle relaxants.

Esmeron may affect the effects of the following medicines:

  • may increase the effect of local anesthetics (such as lidocaine).

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you might be pregnant, or plan to become pregnant, consult your doctor before Esmeron is administered to you.

Breastfeeding should be stopped 6 hours after the use of this medicine.

Driving and using machines

Your doctor will inform you when you can drive and use potentially hazardous machines safely after the administration of Esmeron.

Esmeron contains sodium

This medicine contains less than 23 mg of sodium (1 mmol) per vial; it is essentially "sodium-free".

3. How to use Esmeron

Your doctor will adjust the dose to your needs. You will be given Esmeron before or during the operation. The recommended dose is 0.6 mg per kilogram of body weight, and the effect lasts for 30 to 40 minutes. During the operation, the activity of Esmeron will be monitored. If necessary, you will be given more doses, which will depend on various factors, such as possible interactions with other medicines, the expected duration of the operation, your age, or your state of health.

Your doctor will administer Esmeron to you, either by intravenous injection or by continuous infusion.

If you use more Esmeron than you should

The medical staff will be monitoring the operation, and it is unlikely that you will be given too much Esmeron. However, if this happens, artificial respiration will be maintained until you are able to breathe on your own.

Your doctor may speed up your recovery by giving you a medication that counteracts the effects of the muscle relaxant.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Rare or uncommon (at least 1 in 10,000 patients)

  • increased heart rate (tachycardia)
  • decreased blood pressure (hypotension)
  • increased or decreased effect of Esmeron
  • pain at the injection site
  • prolonged muscle relaxant effect of Esmeron.

Very rare (less than 1 in 10,000 patients)

  • allergic reactions such as changes in blood pressure and heart rate, and shock due to low blood circulation
  • chest pressure due to muscle spasms in the airways (bronchospasm)
  • skin disorders (such as edema, redness, rash, or hives)
  • muscle weakness or paralysis
  • chronic muscle disorder, usually observed after the concomitant administration of Esmeron and corticosteroids (anti-inflammatory medications) in critically ill patients in the Intensive Care Unit (steroid myopathy).

Frequency not known (cannot be estimated from the available data)

  • dilated pupils (mydriasis) or fixed pupils that do not change size with light or other stimuli
  • severe allergic spasm of the coronary blood vessels (Kounis syndrome) that causes chest pain (angina) or heart attack (myocardial infarction).

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Esmeron

Keep this medicine out of the sight and reach of children.

Esmeron is only available in hospitals.

Store in a refrigerator (between 2°C and 8°C). Keep in the original packaging to protect from light.

The product can be stored outside the refrigerator at a temperature of up to 30°C for a maximum of 3 months. The product can be put in and taken out of the refrigerator at any time during the 36-month validity period, but the total storage time outside the refrigerator must not exceed 3 months. The storage period must not exceed the expiry date stated on the packaging.

Do not use this medicine after the expiry date stated on the packaging. The expiry date is the last day of the month indicated.

Disposal of unused medicine and all materials that have come into contact with it will be carried out in accordance with local regulations.

6. Contents of the pack and further information

Composition of Esmeron

  • The active substance is rocuronium bromide. Each ml of solution contains 10 mg of rocuronium bromide.
  • The other ingredients are sodium acetate, sodium chloride, acetic acid, and water for injections. 1 ml of Esmeron contains 1.64 mg of sodium.

Appearance of the product and pack contents

Esmeron is a clear solution for injection and infusion that contains 10 mg/ml of rocuronium bromide. Esmeron is presented in 5 ml vials that contain 50 mg of rocuronium bromide, in packs of 10 vials.

Marketing authorization holder and manufacturer

Marketing authorization holder

Schering-Plough, S.A.; C/ Josefa Valcárcel, 42; 28027 Madrid; Spain

Manufacturer

N.V. Organon; Kloosterstraat 6; 5349 BH Oss; Netherlands

Merck Sharp & Dohme B.V.; Waarderweg 39; 2031 BN Haarlem; Netherlands

Local representative:

Merck Sharp & Dohme of Spain, S.A.; C/ Josefa Valcárcel, 42; 28027 Madrid; Spain.

Tel.: 91 3210600

Date of last revision of this leaflet:12/2022.

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es/)

Online doctors for ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION

Discuss questions about ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

0.0 (0)
Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Camera Book a video appointment
€58
5.0 (140)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Camera Book a video appointment
€50
5.0 (29)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
Camera Book a video appointment
€60

Frequently Asked Questions

Is a prescription required for ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION?
ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION?
The active ingredient in ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION is rocuronium bromide. This information helps identify medicines with the same composition but different brand names.
Who manufactures ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION?
ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION is manufactured by Schering Plough S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to ESMERON 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION?
Other medicines with the same active substance (rocuronium bromide) include ROCURONIUM AGUETTANT 10 mg/mL Injectable Solution in Pre-filled Syringe, ROCURONIUM B. BRAUN 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION, ROCURONIUM HIKMA 10 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media