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DMSA TECHNESCAN 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION

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About the medicine

How to use DMSA TECHNESCAN 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

PACKAGE LEAFLET: Information for the patient

DMSA Technescan 1 mg kit for radiopharmaceutical preparation

Succimer

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your nuclear medicine doctor who is supervising the procedure.
  • If you experience any side effects, talk to your nuclear medicine doctor, even if they are not listed in this leaflet. See section 4.

Contents of the package leaflet:

  1. What DMSA Technescan is and what it is used for
  2. What you need to know before you use DMSA Technescan
  3. How to use DMSA Technescan
  4. Possible side effects
  5. Storage of DMSA Technescan
  6. Contents of the pack and further information

1. What DMSA Technescan is and what it is used for

This medicine is a radiopharmaceutical for diagnostic use only.

DMSA Technescan contains the active substance succimer. It is used for the preparation of a radioactive injectable solution of technetium (99mTc) succimer.

DMSA Technescan is used in adults and children to examine the kidneys. When injected, this medicine accumulates temporarily in the kidneys. Due to its radioactivity, it can be detected outside the body using a special camera and photographs, known as scans, can be taken. These scans provide valuable information about the structure and/or function of your kidneys. The administration of DMSA Technescan involves receiving a small amount of radioactivity. Your doctor and the nuclear medicine doctor have considered that the clinical benefit you will gain from the procedure with the radiopharmaceutical outweighs the risk due to radiation.

Doctor consultation

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2. What you need to know before you use DMSA Technescan

Do not use DMSA Technescan:

  • If you are allergic to succimer or any of the other components of this medicine (listed in section 6), or to any of the components of the radiolabelled product (technetium 99mTc succimer).

Warnings and precautions

Be particularly careful with DMSA Technescan:

  • If you are pregnant or think you may be pregnant.
  • If you are breast-feeding
  • If you have kidney disease.

Talk to your nuclear medicine doctor if any of the above applies to you. This medicine may not be suitable for you. Your nuclear medicine doctor will advise you.

Before administration of DMSA Technescan, you must

  • Drink plenty of water before starting the procedure to urinate frequently during the first hours after its completion.

Children and adolescents

Tell your nuclear medicine doctor if you are under 18 years old.

Other medicines and DMSA Technescan

Tell your nuclear medicine doctor if you are using, have recently used or might use any other medicines, including those obtained without a prescription, as they may interfere with the interpretation of the images.

Your nuclear medicine doctor/doctor may advise you to stop taking the following medicines before the procedure with DMSA Technescan:

  • ammonium chloride, (ammonium salt, a substance present in some cough medicines and in licorice juice)
  • sodium bicarbonate, (medicine given to reduce blood and/or urine acidity)
  • mannitol, (diuretic medicine that helps you produce more urine and eliminate salt and excess water from the body)
  • some antihypertensive medicinesto treat high blood pressure (so-called ACE inhibitors, such as captopril)

Some cancer medicines (methotrexate, cyclophosphamide, vincristine) may also influence or be influenced by DMSA Technescan.

Pregnancy and breast-feeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your nuclear medicine doctor for advice before using this medicine.

You must inform the nuclear medicine doctor beforeadministration of DMSA Technescan if there is any possibility that you may be pregnant, if you have a delayed period or if you are breast-feeding.

In case of doubt, it is important that you consult your nuclear medicine doctor who is supervising the procedure.

If you are pregnant

The nuclear medicine doctor will onlygive you DMSA Technescan during pregnancy if the expected benefit outweighs the risk.

If you are breast-feeding

Ask your nuclear medicine doctor if you are breast-feeding as they may delaytreatment until breast-feeding has stopped. They may also ask you to interrupt breast-feeding for a short periodand discard this milk during this period, until the radioactivity is no longer in your body. Please ask your nuclear medicine doctor when you can restart breast-feeding.

You do not need to avoid close contact with your baby after the procedure.

Driving and using machines

It is considered unlikely that DMSA Technescan will affect your ability to drive or use machines.

DMSA Technescan contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per dose; this is "essentially sodium-free".

3. How to use DMSA Technescan

There are strict rules about the use, handling and disposal of radiopharmaceuticals. DMSA Technescan will only be used in specially controlled areas. This product will only be handled and administered by trained and qualified personnel to use it safely. These people will take special care in the safe use of this product and will inform you of their actions.

The nuclear medicine doctor supervising the procedure will decide on the amount of technetium (99mTc) succimer to be used in your case. This will be the minimum amount necessary to obtain the desired information.

The generally recommended amount to administer to an adult is 30 to 120 MBq(MegaBecquerel, the unit used to express radioactivity).

Use in children and adolescents

In children and adolescents, the amount to be administered will be adjusted according to their body weight.

Administration of DMSA Technescan and performance of the procedure

DMSA Technescan is administered by injection, usually into a vein in the arm.

A single injection is sufficient to perform the procedure that your doctor needs.

After the injection, you will be offered a drink and asked to urinate immediately before starting the procedure.

Duration of the procedure

Scans are usually performed 2 to 3 hours after the injection. Occasionally, they may be delayed until 24 hours after the injection. Your nuclear medicine doctor will inform you about the duration of the procedure.

After administration of DMSA Technescan, you must:

  • Urinate frequently to eliminate the product from your body

Your nuclear medicine doctor will inform you if you need to take special precautions after being given this medicine. If you have any doubts, talk to your nuclear medicine doctor.

If you have been given more DMSA Technescan than you should

Overdose is unlikely because you will receive a precisely controlled single dose of DMSA Technescan by the supervising nuclear medicine doctor. However, in case of overdose, you will receive the appropriate treatment. In particular, the nuclear medicine doctor may advise you to drink plenty of water and urinate frequently to eliminate the remains of radioactivity from your body.

If you have any further questions on the use of DMSA Technescan, ask your nuclear medicine doctor who is supervising the procedure.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Side effects of unknown frequency (cannot be estimated from the available data):

  • Allergic reactionswith symptoms such as skin rash, redness or itching, increased sweating, swelling of the eyes, tongue or throat, eye inflammation, cough, difficulty breathing, nausea, vomiting, increased salivation, abdominal pain, redness or low blood pressure.
  • Circulatory reactionswith symptoms such as fainting, low blood pressure, headache, dizziness, paleness, feeling of weakness or fatigue
  • Reactions at the injection site,with symptoms such as skin rash, swelling or inflammation.

Hospital staff will treat these reactions, if they occur.

This radiopharmaceutical provides low amounts of ionizing radiation associated with a very low risk of cancer and genetic abnormalities.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this leaflet. You can also report side effects directly via the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of DMSA Technescan

You will not need to store this medicine. This medicine is stored under the responsibility of the specialist in suitable premises. The storage of radiopharmaceuticals will be carried out in accordance with national regulations on radioactive materials.

The following information is only for the specialist.

Do not use DMSA Technescan after the expiry date stated on the label after EXP.

6. Contents of the pack and further information

Composition of DMSA Technescan

  • The active substance is succimer (or dimercaptosuccinic acid).

One vial contains 1.2 milligrams of succimer

  • The other components are: inositol, stannous chloride dihydrate (E512), sodium hydroxide (E524) and hydrochloric acid (E507).

Appearance and pack contents of the product

DMSA Technescan is a kit for radiopharmaceutical preparation intended for use only by healthcare professionals. Before use, the powder in the vial is mixed with a radioactive solution called technetium (99mTc) to form a solution of technetium (99mTc) succimer.

DMSA Technescan is packaged in a 10 ml colourless glass type I vial closed with a bromobutyl rubber stopper and sealed with an aluminium cap.

A pack contains 5 vials.

Marketing authorisation holder and manufacturer:

Marketing authorisation holder:

Curium Pharma Spain S.A.

Avenida Doctor Severo Ochoa, N.º 29

28100, Alcobendas, Madrid

Manufacturer:

Curium Netherlands B.V.

Westerduinweg 3

1755 LE Petten

Netherlands

Date of last revision of this leaflet: November 2023

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

This information is intended only for healthcare professionals:

The full technical data sheet for DMSA Technescan is included as a separate document in the product packaging, in order to provide healthcare professionals with further scientific and practical information on the administration and use of this radiopharmaceutical. Please consult the technical data sheet for DMSA Technescan.

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Discuss questions about DMSA TECHNESCAN 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
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Gastroenterology – Digestive health:
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  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
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  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Frequently Asked Questions

Is a prescription required for DMSA TECHNESCAN 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION?
DMSA TECHNESCAN 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in DMSA TECHNESCAN 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION?
The active ingredient in DMSA TECHNESCAN 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION is technetium (99mTc) succimer. This information helps identify medicines with the same composition but different brand names.
Who manufactures DMSA TECHNESCAN 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION?
DMSA TECHNESCAN 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION is manufactured by Curium Pharma Spain S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of DMSA TECHNESCAN 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether DMSA TECHNESCAN 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to DMSA TECHNESCAN 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION?
Other medicines with the same active substance (technetium (99mTc) succimer) include RENOCIS 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION, DTPA TECHNESCAN 20.8 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION, MAG3 RADIOPHARMACY 1 mg KIT FOR RADIOPHARMACEUTICAL PREPARATION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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