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AMOXICILLIN/CLAVULANIC ACID Support Pharma 500 mg/125 mg FILM-COATED TABLETS

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About the medicine

How to use AMOXICILLIN/CLAVULANIC ACID Support Pharma 500 mg/125 mg FILM-COATED TABLETS

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Amoxicillin/Clavulanic Acid Support Pharma 500 mg/125 mg Film-Coated Tablets EFG

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.,for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you (or your child), do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.

Contents of the pack

  1. What Amoxicillin/Clavulanic Acid Support Pharma is and what it is used for
  2. What you need to know before you take Amoxicillin/Clavulanic Acid Support Pharma
  3. How to take Amoxicillin/Clavulanic Acid Support Pharma
  4. Possible side effects
  5. Storage of Amoxicillin/Clavulanic Acid Support Pharma
  6. Contents of the pack and further information

1. What Amoxicillin/Clavulanic Acid Support Pharma is and what it is used for

Amoxicillin/Clavulanic Acid Support Pharma is an antibiotic that eliminates the bacteria that cause infections. It contains two different active substances called amoxicillin and clavulanic acid. Amoxicillin belongs to a group of medicines known as "penicillins" which can sometimes lose their effectiveness (become inactivated). The other component (clavulanic acid) prevents this from happening.

Antibiotics are used to treat bacterial infections and are not effective against viral infections such as the flu or the common cold.

It is essential to follow the instructions regarding dosage, administration interval, and treatment duration indicated by your doctor.

Do not store or reuse this medicine. If you have any leftover antibiotic after completing the treatment, return it to the pharmacy for proper disposal. Do not throw medicines down the drain or in the trash.

Amoxicillin/Clavulanic Acid is used in adults and children to treat the following infections:

  • Middle ear and sinus infections
  • Respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections, including dental infections
  • Bone and joint infections.
Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Amoxicillin/Clavulanic Acid Support Pharma

Do not take Amoxicillin/Clavulanic Acid Support Pharma

  • if you are allergic to amoxicillin, clavulanic acid, to penicillins or to any of the other ingredients of this medicine (listed in section 6)
  • if you have ever had a severe allergic reaction (hypersensitivity) to any other antibiotic. This could include a skin rash or swelling of the face or throat
  • if you have ever had liver or jaundice (yellowing of the skin) problems when taking an antibiotic.

?Do not take Amoxicillin/Clavulanic Acid Support Pharma if you are included in any of the above points.Before starting treatment with this medicine, if you are unsure, consult your doctor or pharmacist.

Warnings and precautions

Consult your doctor or pharmacist before starting to take Amoxicillin/Clavulanic Acid if:

  • you have infectious mononucleosis
  • you are receiving treatment for liver or kidney problems
  • you do not urinate regularly.

If you are unsure whether any of the above symptoms affect you, inform your doctor or pharmacist before taking Amoxicillin/Clavulanic Acid.

In some cases, your doctor may investigate the type of bacteria causing your infection. Depending on the results, you may be prescribed a different formulation of Amoxicillin/Clavulanic Acid or another medicine.

Symptoms to be aware of

Amoxicillin/Clavulanic Acid can worsen certain existing conditions or cause serious side effects. These include allergic reactions, convulsions, and inflammation of the large intestine. You should be aware of certain symptoms while taking this medicine to reduce the risk of problems. See "Symptoms to be aware of" in section 4.

Blood and urine tests

If you are having blood tests (such as red blood cell status or liver function studies) or urine tests (to check glucose levels), inform your doctor or nurse that you are taking Amoxicillin/Clavulanic Acid. This is because this medicine can alter the results of these types of tests.

Other medicines and Amoxicillin/Clavulanic Acid Support Pharma

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

If you are taking allopurinol (used for gout) with Amoxicillin/Clavulanic Acid, you may be more likely to experience a skin allergic reaction.

If you are taking probenecid (used to treat gout), concomitant use of probenecid may reduce the excretion of amoxicillin and is not recommended.

If you are taking anticoagulants (such as warfarin) with Amoxicillin/Clavulanic Acid, more frequent blood tests will be needed.

Amoxicillin/Clavulanic Acid may affect the action of methotrexate (a medicine used to treat cancer and severe psoriasis), penicillins may reduce the excretion of methotrexate and cause a potential increase in side effects.

Amoxicillin/Clavulanic Acid may affect how mycophenolate mofetil (a medicine used to prevent organ rejection in transplant patients) works.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Driving and using machines

Amoxicillin/Clavulanic Acid may cause side effects that can affect your ability to drive or use machines.

Do not drive or operate machinery unless you are feeling well.

Amoxicillin/Clavulanic Acid Support Pharma contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per tablet; this is, essentially "sodium-free".

3. How to take Amoxicillin/Clavulanic Acid Support Pharma

Always take this medicine exactly as your doctor or pharmacist has told you. If you are unsure, consult your doctor or pharmacist.

Adults and children over 40 kg

The recommended dose is:

  • 1 tablet three times a day

Children under 40 kg

It is preferable to treat children under 6 years with the oral suspension of Amoxicillin/Clavulanic Acid or sachets.

Ask your doctor or pharmacist for advice when administering Amoxicillin/Clavulanic Acid tablets to children who weigh less than 40 kg. The tablets are not suitable for children who weigh less than 25 kg.

Patients with kidney and liver problems

  • If you have kidney problems, your dose may be changed. Your doctor may choose a different formulation or another medicine.
  • If you have liver problems, you will have more frequent blood tests to check how your liver is working.

How to take Amoxicillin/Clavulanic Acid Support Pharma

  • Take with meals.
  • Swallow the tablets whole with a glass of water. The score line is to facilitate breaking and swallowing, but not to divide into equal doses. You should take both parts of the tablet at the same time.
  • Space out the doses during the day, at least 4 hours apart. Do not take 2 doses in 1 hour.
  • Do not take Amoxicillin/Clavulanic Acid for more than 2 weeks. If you are still feeling unwell, consult your doctor.

If you take more Amoxicillin/Clavulanic Acid Support Pharma than you should

If you take too much Amoxicillin/Clavulanic Acid, you may experience symptoms such as stomach upset (nausea, vomiting, or diarrhea) or convulsions. Consult your doctor as soon as possible. Take the pack with you to show the doctor.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, telephone 91 562 04 20, indicating the medicine and the amount taken.

If you forget to take Amoxicillin/Clavulanic Acid Support Pharma

If you forget to take a dose, take it as soon as you remember. Do not take the next dose too soon, wait at least 4 hours before taking the next dose. Do not take a double dose to make up for forgotten doses.

If you stop taking Amoxicillin/Clavulanic Acid Support Pharma

Continue taking Amoxicillin/Clavulanic Acid until you finish the treatment, even if you feel better. You need to complete the full treatment to cure the infection. If you do not, the surviving bacteria may cause the infection to return.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Symptoms to be aware of

Allergic reactions

  • skin rash
  • inflammation of blood vessels (vasculitis) which can appear as red or purple spots on the skin, but can affect other parts of the body
  • fever, joint pain, swollen glands in the neck, armpits, or groin
  • swelling, sometimes of the face or mouth (angioedema), which can cause difficulty breathing
  • collapse

?Contact a doctor immediatelyif you experience any of these symptoms. Stop taking Amoxicillin/Clavulanic Acid Support Pharma.

Inflammation of the large intestine

Inflammation of the large intestine, which causes watery diarrhea, usually with blood and mucus, stomach pain, and/or fever.

?Contact your doctor immediatelyif you experience any of these symptoms.

Very common side effects

May affect more than 1 in 10 people

  • diarrhea (in adults).

Common side effects

May affect up to 1 in 10 people

  • thrush (Candida - fungal infection of the vagina, mouth, or mucous membranes)
  • nausea, especially when taking high doses (if this happens, take Amoxicillin/Clavulanic Acid with meals)
  • vomiting
  • diarrhea (in children)

Uncommon side effects

May affect up to 1 in 100 people

  • skin rash, itching
  • increased itchy rash (urticaria)
  • indigestion
  • dizziness
  • headache.

Uncommon side effects that may appear in your blood tests:

  • increase in some substances (enzymes) produced by the liver.

Rare side effects

May affect up to 1 in 1,000 people

  • skin rash, which can form blisters that look like small targets (central dark spot surrounded by a paler area, with a dark ring around the edge - erythema multiforme)

?If you have any of these symptoms, consult a doctor urgently.

Rare side effects that may appear in your blood tests:

  • low count of cells involved in blood clotting
  • low count of white blood cells

Frequency not known

Frequency cannot be estimated from the available data.

  • Allergic reactions (see above)
  • Inflammation of the large intestine (see above)
  • Inflammation of the protective membranes surrounding the brain and spinal cord (aseptic meningitis).
  • Severe skin reactions:
  • widespread rash with blisters and peeling of the skin, particularly around the mouth, nose, eyes, and genitals (Stevens-Johnson syndrome), and in its most severe form, causing widespread peeling of the skin (more than 30% of the body surface - toxic epidermal necrolysis)
  • widespread rash with small blisters containing pus (bullous exfoliative dermatitis)
  • red rash with bumps under the skin and blisters (pustular exanthematous eruption).
  • flu-like symptoms with skin rash, fever, gland inflammation, and abnormal blood test results (such as increased white blood cells (eosinophilia) and elevated liver enzymes) (drug reaction with eosinophilia and systemic symptoms (DRESS)).
  • Chest pain in the context of allergic reactions, which can be a symptom of allergy-induced heart attack (Kounis syndrome).
  • Drug-induced enterocolitis syndrome (DIES):
  • DIES has been reported mainly in children receiving amoxicillin. It is a certain type of allergic reaction with the main symptom of repeated vomiting (1-4 hours after taking the medicine). Other symptoms may include abdominal pain, lethargy, diarrhea, and low blood pressure.
    • Crystals in the urine that cause acute kidney injury.
    • Rash with blisters arranged in a circle with a central crust or like a string of pearls (linear IgA disease).
    • Acute pancreatitis (inflammation of the pancreas)

    If you have severe and persistent stomach pain, this could be a sign of acute pancreatitis.

    ?Contact a doctor immediately if you have any of these symptoms.

    • inflammation of the liver (hepatitis)
    • jaundice, caused by increased bilirubin in the blood (a substance produced by the liver) that can make the skin and whites of the eyes turn yellow
    • inflammation of the kidney ducts
    • delayed blood clotting
    • hyperactivity
    • convulsions (in patients taking high doses of Amoxicillin/Clavulanic Acid or with kidney problems)
    • black hairy tongue

    Side effects that may appear in your blood or urine tests:

    • significant reduction in the number of white blood cells
    • low count of red blood cells (hemolytic anemia)
    • crystals in the urine, which cause acute kidney injury.

    Reporting of side effects

    If you experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Website: www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

    5. Storage of Amoxicillin/Clavulanic Acid Support Pharma

    Keep out of the sight and reach of children.

    Do not use this medicine after the expiry date which is stated on the carton, after EXP. The expiry date refers to the last day of the month shown.

    Do not store above 25°C.

    Store in the original package to protect from moisture.

    Medicines should not be disposed of via wastewater or household waste. Return the containers and any unused medicines to the pharmacy. If you are unsure, ask your pharmacist how to dispose of containers and unused medicines. This will help protect the environment.

    6. Container Content and Additional Information

    Composition of Amoxicillin/Clavulanic Acid Support Pharma 500 mg/125 mg Film-Coated Tablets

    • The active ingredients are amoxicillin and clavulanic acid. Each tablet contains: 500 mg of amoxicillin (as amoxicillin trihydrate) and 125 mg of clavulanic acid (as potassium clavulanate).
    • The other components (excipients) are: anhydrous colloidal silica, magnesium stearate, sodium carboxymethyl starch (type A), and microcrystalline cellulose, Opadry Oy-S-7300 (hypromellose, macrogol, titanium dioxide (E171)), dimeticone.

    Appearance of the Product and Container Content

    Film-coated tablets of elongated shape, white or almost white in color, with a score line and engraved with A/C.

    Blister pack of polyamide-aluminum-PVC / aluminum foil.

    Containers containing 30 or 500 film-coated tablets.

    Only some pack sizes may be marketed.

    Marketing Authorization Holder and Manufacturer

    Holder:

    SUPPORT PHARMA Laboratories, S.L.

    General Álvarez de Castro 39, 28010 Madrid

    Spain

    Manufacturer:

    REIG JOFRE Laboratory, S.A.

    Jarama 111, Industrial Estate

    45007 Toledo

    Date of the Last Revision of this Leaflet: June 2023

    Detailed and updated information on this medicinal product is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es

    -------------------------------------------------------------------------------------------------------------------

    Medical Advice/Education

    Antibiotics are used to treat bacterial infections. They are not effective against viral infections.

    Sometimes a bacterial infection does not respond to antibiotic treatment. One of the most common reasons for this is that the bacteria causing the infection are resistant to the antibiotic being taken. This means that the bacteria can survive or grow despite the antibiotic.

    Bacteria can become resistant to antibiotics for many reasons. Using antibiotics properly can reduce the chances of bacteria becoming resistant to them.

    When your doctor prescribes an antibiotic, it is only for the course of your illness. Paying attention to the following tips will help you prevent the appearance of resistant bacteria that can make the antibiotic ineffective.

    1. You should not take an antibiotic unless it has been specifically prescribed for you, and you should only use it for the infection for which it was prescribed.
    2. You should not take antibiotics that have been prescribed for other people, even if they have the same or a similar infection to yours.
    3. You should not give antibiotics that have been prescribed for you to other people.
    4. If you still have antibiotic left after completing the treatment, return all unused medication to your pharmacy to ensure that disposal requirements are met.

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    General surgery 12 years exp.

    Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

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    Alexander Nazarchuk

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    Frequently Asked Questions

    Is a prescription required for AMOXICILLIN/CLAVULANIC ACID Support Pharma 500 mg/125 mg FILM-COATED TABLETS?
    AMOXICILLIN/CLAVULANIC ACID Support Pharma 500 mg/125 mg FILM-COATED TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
    What is the active substance in AMOXICILLIN/CLAVULANIC ACID Support Pharma 500 mg/125 mg FILM-COATED TABLETS?
    The active ingredient in AMOXICILLIN/CLAVULANIC ACID Support Pharma 500 mg/125 mg FILM-COATED TABLETS is amoxicillin and beta-lactamase inhibitor. This information helps identify medicines with the same composition but different brand names.
    Who manufactures AMOXICILLIN/CLAVULANIC ACID Support Pharma 500 mg/125 mg FILM-COATED TABLETS?
    AMOXICILLIN/CLAVULANIC ACID Support Pharma 500 mg/125 mg FILM-COATED TABLETS is manufactured by Laboratorios Support Pharma S.L.. Pharmacy brands and packaging may differ depending on the distributor.
    Which doctors can assess the use of AMOXICILLIN/CLAVULANIC ACID Support Pharma 500 mg/125 mg FILM-COATED TABLETS online?
    Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether AMOXICILLIN/CLAVULANIC ACID Support Pharma 500 mg/125 mg FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
    What are the alternatives to AMOXICILLIN/CLAVULANIC ACID Support Pharma 500 mg/125 mg FILM-COATED TABLETS?
    Other medicines with the same active substance (amoxicillin and beta-lactamase inhibitor) include AMOXICILLIN / CLAVULANIC ACID SANDOZ 250 mg/62.5 mg/5 ml ORAL SUSPENSION POWDER, AMOXICILLIN CLAVULANATE POWDER FOR SOLUTION FOR INFUSION 2000 mg/200 mg, AMOXICILLIN CLAVULANATE SUN 500 mg/125 mg FILM-COATED TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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