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Medicines commonly prescribed for Goitre (enlarged thyroid gland)
For informational purposes only. Always consult a doctor before using any medicine.
Dosage form: TABLET, 125 microgramsActive substance: levothyroxine sodiumManufacturer: Aristo Pharma GmbhPrescription requiredDosage form: TABLET, 150 MICROGRAMSActive substance: levothyroxine sodiumManufacturer: Teva Pharma S.L.U.Prescription requiredDosage form: TABLET, 50 mcgActive substance: levothyroxine sodiumPrescription required
A goitre is an enlargement of the thyroid gland, the small butterfly-shaped organ at the front of the neck. From the outside it shows as a swelling below the Adam's apple that moves upwards when you swallow. The enlargement itself is not a diagnosis but a finding: the gland may be working normally, overactively or underactively, and what happens next depends on which. Most cases are not serious, but examination and blood tests are always needed.
Symptoms
The main sign is a painless swelling at the front of the neck. If the enlargement is significant, others follow:
- a feeling of a lump or pressure in the throat;
- difficulty swallowing, particularly solid food;
- hoarseness or a change in the sound of your voice;
- a cough that will not settle;
- noisy or laboured breathing, especially when lying down;
- a sense of tightness when raising your arms.
Signs that the gland is not working properly deserve separate attention. With too much hormone: weight loss despite a normal appetite, palpitations, trembling hands, sweating, irritability, insomnia. With too little: tiredness, feeling cold, weight gain, dry skin, hair loss, constipation, low mood.
When to seek help
Urgently, if breathing or swallowing becomes difficult, or your breathing turns noisy: an enlarged gland can press on the airway. Call the emergency number rather than driving yourself.
As a routine appointment, if:
- you have noticed a swelling in your neck;
- a nodule can be felt, or it is growing quickly;
- your voice has changed without a cold;
- symptoms of too much or too little thyroid hormone have appeared;
- the lump is hard, immobile, or the lymph nodes in your neck have enlarged;
- you had radiotherapy to the neck in the past, or relatives with thyroid cancer.
Causes
- Iodine deficiency — the most common cause worldwide; the gland grows trying to compensate for a shortage of raw material for hormones;
- autoimmune thyroiditis, or Hashimoto's disease, where the immune system damages the gland and function usually falls;
- Graves' disease — an autoimmune process with excessive hormone production;
- nodules and multinodular goitre, mostly benign;
- thyroiditis after a viral infection, with tenderness of the gland;
- hormonal stages — puberty, pregnancy, menopause;
- medication, including lithium and iodine-containing drugs;
- thyroid cancer — an uncommon cause, usually presenting as a single firm nodule.
How it is investigated
The starting point is a TSH blood test, which shows how the gland is functioning; if it is abnormal, free T4 and T3 are added, and antibodies where an autoimmune process is suspected. Next comes a thyroid ultrasound, which assesses size, structure and nodules. If a nodule is large or looks suspicious on ultrasound, a fine-needle aspiration is done: an outpatient sampling of cells that is well tolerated. For a large goitre extending behind the breastbone, a CT scan and breathing tests may be needed.
Treatment
A small goitre with normal function is usually just monitored, with ultrasound and blood tests. Otherwise:
- reduced function is treated with levothyroxine replacement;
- increased function with antithyroid drugs, radioactive iodine or surgery;
- iodine deficiency by correcting the diet and, where appropriate, supplements;
- surgery is offered when the goitre presses on the windpipe or oesophagus, grows rapidly, raises suspicion of malignancy, or is cosmetically troubling.
Common questions
Is a goitre cancer? In the great majority of cases, no. Malignant nodules are a small proportion, and ultrasound and needle sampling exist precisely to rule them out.
Should I take iodine on my own initiative? No. In some conditions, Graves' disease among them, extra iodine makes things worse. The decision follows the blood tests.
Can a goitre disappear by itself? Enlargement linked to pregnancy or a viral thyroiditis often resolves. A nodular goitre usually persists.
Online consultation
In an online appointment a doctor can go through your symptoms, arrange the blood tests and ultrasound needed, interpret results you already have, explain whether a needle sample is required and advise which specialist to see in person.
This article is for general information and does not replace a consultation with a doctor.
Medically reviewed by
Reviewed on Jul 24, 2026
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