Erythema nodosum

Erythema nodosum is a condition that causes painful patches of skin that look red or darker than the surrounding skin. It usually goes away by itself, but it can sometimes be a sign of something serious like an inflammatory bowel condition, such as Crohn's disease.

This page provides general information and does not replace a doctor’s consultation. If symptoms are severe, persistent or worsening, seek medical advice promptly.

Erythema nodosum is a condition that causes painful patches of skin that look red or darker than the surrounding skin. It usually goes away by itself, but it can sometimes be a sign of something serious like an inflammatory bowel condition, such as Crohn's disease.

Symptoms of erythema nodosum

If you have erythema nodosum, you may have flu-like symptoms before or at the same time as you get the patches on your skin.

For example, you may:

  • have a high temperature
  • have swollen, aching joints, particularly the knees, ankles and wrists
  • feel generally unwell

The skin usually heals on its own within 3 to 8 weeks without leaving a scar. But other symptoms, such as joint pain and swelling, can last for several weeks.

Things you can do to ease the pain of erythema nodosum

There are some things you can do to help ease the pain of erythema nodosum.

Do

  • try taking ibuprofen

  • rest with your feet raised on a pillow

  • try to avoid long periods of standing, walking and running

  • put a cool wet compress, like a damp cloth, on the affected area

A pharmacist can help with erythema nodosum

If you're in pain, a pharmacist can recommend:

  • stronger painkillers
  • supportive bandages or stockings

They may also suggest you see a GP.

See a GP if:

  • you have a painful skin condition that affects your daily life
  • lots of lumps or marks start appearing on your skin
  • the lumps or marks do not go away after 8 weeks

What happens at your GP appointment

The GP may be able to tell if you have erythema nodosum by looking at the inflamed areas of skin.

Tests may be needed to find the cause. This may include a biopsy, where a small sample of skin is taken so it can be looked at under a microscope.

Treatments for erythema nodosum

Treatment for erythema nodosum depends on the cause.

If it's caused by another condition, treating that condition may help. For example, if it’s caused by an infection, you may be given antibiotics.

If the GP thinks a medicine you've been taking might be causing erythema nodosum, they may advise you to stop taking it. Do not stop taking medicines without asking a GP first.

If your symptoms have lasted a long time or they keep returning, other treatments, such as steroid tablets, may be recommended.

Causes of erythema nodosum

Erythema nodosum can be caused by lots of things, but often the cause is unknown.

Common causes include:

  • inflammatory bowel conditions like Crohn's disease and ulcerative colitis
  • bacterial infections, such a throat infection, chest infection or lung infection (tuberculosis)
  • a rare condition where small patches of swollen tissue develop in organs, such as the lungs, lymph nodes or skin (sarcoidosis)
  • a reaction to some medicines, including the contraceptive pill and some antibiotics
Consult with a doctor about Erythema nodosum

Consult with a doctor about Erythema nodosum

Discuss your symptoms and possible next steps with a doctor online.

Online doctors for Erythema nodosum

Discuss your symptoms and possible next steps for Erythema nodosum with a doctor online.

Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
€86
Doctor
5.0(19)

Nuno Tavares Lopes

Family medicineGeneral medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

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