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EREBRA

EREBRA

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Doctor

Hocine Lokchiri

General medicine21 years of experience

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use EREBRA

INSTRUCTIONS for medical use of the medicinal product PHENCAROL®(PHENCAROL)

Composition

active substance: chlorpheniramine; 1 tablet contains chlorpheniramine hydrochloride 25 mg; excipients: potato starch, sucrose, calcium stearate.

Pharmaceutical form

Tablets.

Main physical and chemical properties

Flat-cylindrical tablets of white or almost white color, with a facet.

Pharmacotherapeutic group

Antihistamines for systemic use.

ATC code R06A X31.

Pharmacological properties

Pharmacodynamics

Chlorpheniramine is a derivative of quinuclidylcarbinol, which reduces the effect of histamine on organs and systems. Chlorpheniramine is a competitive blocker of H1-receptors. Additionally, it activates the enzyme diamine oxidase, which breaks down approximately 30% of endogenous histamine. This explains the effectiveness of chlorpheniramine in patients who are insensitive to other antihistamines. Chlorpheniramine poorly penetrates the blood-brain barrier and has little effect on serotonin desamination processes in the brain, weakly affects monoamine oxidase activity. The antihistamine properties of chlorpheniramine are associated with the presence of a quinuclidine ring in its structure and the distance between the diphenylcarbinol group and the nitrogen atom. In terms of antihistamine activity and duration of action, chlorpheniramine surpasses dimedrol. Chlorpheniramine reduces the toxic effect of histamine, relieves or weakens its bronchoconstrictor effect and spasmodic effect on the smooth muscles of the intestine, has a moderate antiserotonin and weak anticholinergic effect, well-expressed antipruritic and desensitizing properties. Chlorpheniramine weakens the hypotensive effect of histamine and its effect on capillary permeability, does not directly affect cardiac activity and arterial pressure, does not have a protective effect in aconitine arrhythmias.

Chlorpheniramine does not suppress the central nervous system, but in case of individual increased sensitivity, a weak sedative effect is possible. The drug is slightly lipophilic, and its content in brain tissue is low (less than 0.05), which explains the absence of a suppressive effect on the central nervous system.

Pharmacokinetics

Chlorpheniramine is quickly absorbed from the gastrointestinal tract and is already present in the body's tissues after 30 minutes. The maximum concentration is reached after 1 hour.

Metabolites and the unchanged fraction of chlorpheniramine are mainly excreted in the urine, bile, and through the lungs within 48 hours.

Clinical characteristics

Indications

Pollinosis, food and drug allergy, other allergic diseases, acute and chronic urticaria, angioedema (Quincke's edema), hay fever, allergic rhinopathy, dermatoses (eczema, psoriasis, neurodermatitis, skin itching), as well as infectious-allergic reactions with a bronchospastic component.

Contraindications

Increased sensitivity to chlorpheniramine or to the excipients of the medicinal product.

Interaction with other medicinal products and other types of interactions

Phencarol®does not enhance the suppressive effect of alcohol and sedatives on the central nervous system, has weak M-cholinoblocking properties, but with decreased motor activity of the gastrointestinal tract, the absorption of slowly absorbed medications may be enhanced (e.g., indirect anticoagulants - coumarins).

Special warnings and precautions for use

The drug should be prescribed with caution to patients with severe cardiovascular, gastrointestinal, renal, and hepatic diseases.

The drug contains sucrose, which should be taken into account in patients with diabetes.

Patients with rare hereditary diseases, such as fructose intolerance or sucrase-isomaltase insufficiency, should not use the drug.

Use during pregnancy or breastfeeding

There are no sufficient studies in animals to assess the impact of the medicinal product on pregnancy.

The drug is contraindicated during the first trimester of pregnancy. It is not recommended to use the drug during the second and third trimesters of pregnancy.

There are no data on the penetration of the drug into breast milk, so the use of Phencarol®is contraindicated during breastfeeding.

Ability to affect the reaction rate when driving vehicles or using other mechanisms

Persons whose work requires rapid physical or mental reactions (drivers) should first establish individual sensitivity (through short-term use) to the sedative effect. If there is increased sensitivity, such persons should be especially careful when using the drug.

Method of administration and dosage

Phencarol®should be taken orally immediately after meals.

A single dose for adults is 25-50 mg 2-4 times a day.

In case of pollinosis, a daily dose of less than 75 mg is ineffective. The maximum daily dose is 200 mg. The duration of the treatment course is 10-15 days.

For children over 12 years old, 25 mg 2-3 times a day. The duration of the treatment course is 10-20 days. If necessary, the treatment course can be repeated (after consulting a doctor).

If a dose is missed, the treatment course should be continued using the previously prescribed doses. If necessary, consult a doctor.

Children

The drug can be used in children over 12 years old.

For children under 12 years old, it is recommended to use the drug in a different dosage (Phencarol®, 10 mg tablets).

Overdose

There have been no reports of overdose. A daily dose of up to 300 mg/day does not cause serious clinically significant side effects. High doses may cause dryness of the mucous membranes, headache, nausea, vomiting, epigastric pain, and dyspeptic symptoms.

Symptomatic treatment should be performed if necessary.

There is no specific antidote.

Side effects

From the nervous system: dizziness, headache.

Sometimes a weak sedative effect is possible, which manifests as weakness, drowsiness, slowing of response reactions.

From the gastrointestinal tract: dryness of the mucous membranes of the oral cavity, dyspeptic symptoms (nausea, vomiting, bitterness in the mouth), which usually pass when the dose is reduced or the drug is discontinued.

From the respiratory system, organs of the thoracic cavity, and mediastinum: sneezing, difficult breathing.

From the psyche: anxiety.

From the kidneys and urinary tract: proteinuria, interstitial nephritis.

From the musculoskeletal and connective tissue: joint pain.

From the organs of vision: lacrimation.

In persons with gastrointestinal diseases, the possibility of side effects increases.

If any undesirable effects occur, the use of the medicinal product should be discontinued and a doctor consulted.

Shelf life

5 years.

Storage conditions

Store in the original packaging at a temperature not exceeding 25 °C.

Store in a place inaccessible to children.

Packaging

10 tablets in a blister pack. 2 blister packs in a cardboard box.

Release category

Without a prescription.

Manufacturer

JSC "Olainfarm" / AS "Olainfarm".

Manufacturer's location and address

5 Rupnicu street, Olaine, LV-2114, Latvia / 5 Rupnicu iela, Olaine, LV-2114, Latvija.

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Online doctors for EREBRA

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for EREBRA – subject to medical assessment and local rules.

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He offers compassionate, evidence-based support for individuals dealing with:

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  • psychosomatic symptoms and chronic stress
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Dr. Laafif combines scientific expertise with human empathy, helping patients restore emotional balance, improve daily functioning, and regain confidence in their recovery journey.
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Hocine Lokchiri

General medicine21 years of experience

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
CameraBook a video appointment
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With a patient-centred approach, Dr. Raevskii helps individuals manage both chronic illnesses and complex oncological cases. His consultations are guided by current medical standards and adapted to each patient’s needs.

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Dr Kovalenko combines evidence-based practice with a respectful, patient-centred approach. She takes time to explain, listens attentively, and helps each person make confident, informed decisions about their health.

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  • long-term care for chronic paediatric conditions
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Dr Benko sees paediatrics as a space for partnership with families – not only to treat illness, but to guide each child’s health journey with clarity, empathy and trust. Her goal is for every family to feel supported in making confident, informed decisions for their child’s wellbeing.
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  • anaemia and other haematological changes
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Many patients reach out when they experience new or worsening symptoms, fluctuations in blood pressure, non-severe chest discomfort, breathing symptoms, digestive issues, suspected infections, chronic fatigue or concerns that affect daily life. He also helps patients understand test results, adjust existing treatment plans and navigate long-term health strategies safely and effectively.

When clinically appropriate, Dr. Altaf can also provide health and fitness certificates, including documentation required for physical activity, sports participation or gym use, based on the patient’s health status and medical indications.

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