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PROBIC 50 mg FILM-COATED TABLETS

Ask a doctor about a prescription for PROBIC 50 mg FILM-COATED TABLETS

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Doctor

Dmytro Horobets

Family medicine7 years of experience

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use PROBIC 50 mg FILM-COATED TABLETS

Introduction

Patient Information Leaflet

Probic 50 mg film-coated tablets

Bicalutamide

Read this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.

Contents of the pack

  1. What is Probic and what is it used for
  2. What you need to know before you take Probic
  3. How to take Probic
  4. Possible side effects
  5. Storage of Probic
  6. Contents of the pack and further information

1. What is Probic and what is it used for

Probic contains bicalutamide, which belongs to a group of medicines called anti-androgens. This means that it interferes with some of the actions of male sex hormones (androgens) in the body. It also reduces the amount of male hormones produced in the body.

This medicine is used for certain prostate conditions, in combination with other treatments, such as medicines that reduce the levels of androgens in the body.

2. What you need to know before you take Probic

Do not take Probic

  • If you are allergic to bicalutamide or any of the other ingredients of this medicine.

(listed in section 6).

  • If you are taking terfenadine or astemizol, used to treat allergies, or cisapride, used to treat heartburn and acid reflux.
  • Bicalutamide should not be given to women, children, or adolescents.

Warnings and precautions

  • If you have any liver problems. This medicine should only be taken after your doctor has carefully considered the potential benefits and risks. If this is the case, your doctor will need to perform regular liver function tests.
  • If you have any heart problems. Your doctor will need to monitor your heart function.
  • If you have severe kidney problems. Caution is necessary, as there is no experience with the use of bicalutamide in these cases.

If you are admitted to hospital, inform the medical staff that you are taking this medicine.

Only stop taking the tablets if your doctor tells you to.

Tell your doctor if you have any heart or blood vessel problems, or if you are being treated for them, including medicines to control your heart rhythm (arrhythmias). The risk of heart rhythm problems may increase when using Probic.

Using Probic with other medicines:

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. Bicalutamide should not be used with the following medicines:

  • terfenadine or astemizol (for hay fever or allergy)
  • cisapride (for stomach problems)

If you take Bicalutamide with some of the following medicines, the effect of bicalutamide or the other medicine may be affected. Consult your doctor before taking Probic with the following medicines:

  • warfarin or any medicine to prevent blood clots
  • ciclosporin (used to suppress the immune system to prevent and treat transplant rejection or bone marrow transplant)
  • midazolam (a medicine used to relieve anxiety before surgery or certain procedures or as an anesthetic before and during surgery)
  • cimetidine (to treat stomach ulcers)
  • ketoconazole (used to treat fungal infections of the skin and nails)
  • calcium channel blockers (e.g., diltiazem or verapamil, used to treat high blood pressure or certain heart conditions)

Probic may interfere with some medicines used to treat heart rhythm problems (e.g., quinidine, procainamide, amiodarone, and sotalol) or may increase the risk of heart rhythm problems when used with other medicines (e.g., methadone (used for pain relief and detoxification), moxifloxacin (an antibiotic), antipsychotics used to treat severe mental illnesses).

Taking Probic with food and drinks

Taking food does not affect the efficacy of the medicine.

Pregnancy, breast-feeding, and fertility:

Bicalutamide should not be taken by women, including pregnant or breast-feeding women.

The fertility of male patients may be temporarily reduced due to treatment with bicalutamide, even with temporary infertility.

Driving and using machines:

It is unlikely that Probic will affect your ability to drive or use machines. However, you should be cautious if you experience drowsiness.

Probic contains lactose

If your doctor has told you that you have an intolerance to some sugars, consult them before taking this medicine.

3. How to take Probic

Follow exactly the instructions of your doctor or pharmacist. If you are unsure, consult your doctor or pharmacist again.

The recommended dose in adults is one tablet per day.

Swallow the tablet whole with water.

Try to take the tablet at the same time each day.

If you take more Probic than you should

If you ingest more than the normal dose, contact your doctor or the nearest hospital. In case of overdose or accidental ingestion, consult the Toxicology Information Service. Telephone 91 5620420.

If you forget to take Probic

Do not take a double dose to make up for forgotten doses. If you forget a dose, do not take an extra tablet, simply continue with your usual treatment.

4. Possible side effects

Contact your doctor or pharmacist immediately if you experience any of the following side effects:

  • Severe breathing difficulties, or sudden worsening of breathing difficulties, possibly with cough or fever. Some patients taking bicalutamide develop inflammation of the lungs called pulmonary disease. This side effect is uncommon (less than 1 in 100 but more than 1 in 1,000 patients).
  • Severe skin itching (with lumps) or swelling of the face, lips, tongue, and/or throat, which can cause difficulty swallowing. These allergic reactions are uncommon (less than 1 in 100 patients).

Other possible side effects of this medicine are:

Very common side effects (may affect more than 1 in 10 patients):

Breast tenderness or enlargement, Hot flushes.

Common side effects (may affect up to 1 in 100 patients):

Nausea, Diarrhea, Itching, Weakness, Yellowing of the skin and eyes (jaundice).

Uncommon side effects (may affect up to 1 in 1,000 patients):

Vomiting, Dry skin.

Rare side effects (frequency cannot be estimated from the available data):

Changes in the electrocardiogram (ECG) (prolongation of the QT interval).

Occasionally, the use of this medicine may be associated with changes in your blood that may require your doctor to perform certain blood tests.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the national reporting system. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Probic

Keep this medicine out of the sight and reach of children.

This medicine does not require any special storage conditions.

Store in the original package.

Do not use this medicine after the expiry date which is stated on the packaging after EXP. The expiry date is the last day of the month shown.

Medicines should not be disposed of via wastewater or household waste. Return any unused medicine to a pharmacy for disposal. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and further information

Composition of Probic

  • The active substance is bicalutamide. Each tablet contains 50 mg of bicalutamide.
  • The other ingredients are: Core: lactose monohydrate, povidone K-30, sodium starch glycolate (from potato), magnesium stearate. Coating: Opadry white Y-7-100.

Appearance and packaging of the product

Probic 50 mg film-coated tablets are white, round, and biconvex.

Each pack contains 30 film-coated tablets in PVC/PVDC/Aluminum blisters.

Marketing authorisation holder and manufacturer

Marketing authorisation holder

Laboratorios Q Pharma, S.L.

C/ Moratín 15 Entlo, Oficinas 6-7

03008 Alicante

SPAIN

Responsible for release:

TECNIMEDE SOCIEDADE TECNICO-MEDICINAL, S.A.

Rua Prof. Henrique de Barros, edificio Sagres 3ª

A Prior Velho P-2685-338 Portugal

)

This leaflet was approved in:

November 2013

“Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es”

About the medicine

How much does PROBIC 50 mg FILM-COATED TABLETS cost in Spain ( 2026)?

The average price of PROBIC 50 mg FILM-COATED TABLETS in January, 2026 is around 42.37 EUR. Prices may vary depending on the region, pharmacy, and whether a prescription is required. Always check with a local pharmacy or online source for the most accurate information.

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Online doctors for PROBIC 50 mg FILM-COATED TABLETS

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for PROBIC 50 mg FILM-COATED TABLETS – subject to medical assessment and local rules.

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Iryna Reznychenko

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Dr Iryna Reznychenko is an obstetrician-gynaecologist, paediatric gynaecologist, and certified lactation consultant. She provides online consultations for women at all stages of life – from adolescence to menopause. Her work combines medical care for gynaecological conditions with dedicated support for breastfeeding challenges, both physical and emotional.

Areas of expertise:

  • interpretation of test results and personalised treatment planning
  • menstrual irregularities, PCOS, endometriosis
  • abnormal uterine bleeding, endometrial hyperplasia, cervical dysplasia
  • care during perimenopause and menopause, hormonal balance, cancer prevention
  • breastfeeding issues: nipple pain, cracked skin, blocked ducts, low milk supply
  • support during the postpartum and lactation period
Dr Reznychenko offers a clear, attentive and professional approach. Her consultations help prevent minor discomforts from developing into more serious concerns – all in a convenient online format.
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Dmytro Horobets

Family medicine7 years of experience

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Dr. Raevskii provides medical care in the following areas:

  • Diagnosis and management of common conditions: hypertension, diabetes, respiratory and digestive disorders.
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  • Supportive care for oncology patients – pain control, symptom relief, and side effect management.
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  • Development of tailored treatment plans based on clinical guidelines.

With a patient-centred approach, Dr. Raevskii helps individuals manage both chronic illnesses and complex oncological cases. His consultations are guided by current medical standards and adapted to each patient’s needs.

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Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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  • Male hypogonadism – age-related or hormonal, including diagnostics and therapy
  • Metabolic syndrome, prediabetes, lipid disorders – risk assessment, lifestyle recommendations, and medical treatment
  • Calcium metabolism disorders – diagnosis and management of osteoporosis, hyperparathyroidism, and hypoparathyroidism
Dr Neshta applies current clinical guidelines and diagnostic tools, offering medical support adapted to each patient’s individual needs — all in an accessible online format.
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Key areas of expertise:

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  • Inflammatory diseases of the genitourinary system: acute and chronic cystitis, pyelonephritis, epididymitis, orchitis, urethritis.
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Dr. Eremeishvili applies an integrated approach to each case. This includes thorough preoperative preparation, postoperative observation, and regular dynamic follow-up during the treatment process to achieve the best possible outcomes. All diagnostic and therapeutic recommendations are based on current evidence-based medicine and comply with the recommendations of the European Association of Urology, guaranteeing high-quality and effective care.

If you are seeking qualified assistance in diagnosing or treating urological conditions, book an online consultation with Dr. Giorgi Eremeishvili. Get expert support, accurate diagnosis, and a personalized treatment plan from the comfort of your home.

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Dr. Tabeshadze takes a patient-centred approach based on evidence-based medicine. Her goal is to help patients achieve hormonal balance, manage chronic conditions effectively, and improve overall well-being through targeted, personalised care.
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Cardiology – Diagnosis and treatment of:

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General internal medicine and preventive care:
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Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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