Vitaminum E 400 mg Hasco

Leaflet attached to the packaging: patient information

VITAMINUM E 400 mg HASCO

400 mg, soft capsules
int-rac-α- Tocopheryl acetate

Please read the contents of the leaflet carefully before using the medicine, as it contains important information for the patient.

• Please keep this leaflet, so that you can read it again if you need to.
• If you have any doubts, you should consult a doctor, pharmacist, or nurse.
• This medicine has been prescribed specifically for you. Do not pass it on to others. The medicine may harm another person, even if their symptoms are the same.
• If the patient experiences any side effects, including any side effects not listed in this leaflet, they should inform their doctor, pharmacist, or nurse. See section 4.

Table of contents of the leaflet

• 1. What is Vitaminum E 400 mg Hasco and what is it used for
• 2. Important information before using Vitaminum E 400 mg Hasco
• 3. How to use Vitaminum E 400 mg Hasco
• 4. Possible side effects
• 5. How to store Vitaminum E 400 mg Hasco
• 6. Contents of the packaging and other information

1. What is Vitaminum E 400 mg Hasco and what is it used for

Vitamin E is one of the essential nutrients, but its role is not yet fully understood. Together with catalase, superoxide dismutase, glutathione peroxidase, and selenium, it is part of the system that protects cells from the effects of oxygen free radicals. It protects polyunsaturated fatty acids in cell membranes and other cell structures, stabilizes cell membranes and cell organelles, and prevents hemolysis of red blood cells.
Protection against oxidative damage appears to be important in the development and functioning of the nervous and muscular systems.
Vitamin E may also act as a cofactor in certain enzyme systems. It participates in glucose oxidation and glycogenolysis. It is involved in lipid metabolism: prostaglandins and cholesterol.
Epidemiological studies indicate a relationship between daily vitamin E intake and the risk of coronary heart disease, atherosclerosis, and other diseases whose pathogenesis is associated with oxidative stress. Vitamin E reduces the aggregatory activity of platelets.

Indications for use:

• treatment of vitamin E deficiency caused by impaired bile secretion, chronic enteritis, prolonged improper nutrition, and metabolic disorders;
• supportive treatment in atherosclerosis, coronary heart disease, cholesterol prophylaxis, and stroke prevention (especially in people living in a polluted environment, exposed to stress, or smokers), in thrombophlebitis, intermittent claudication, and ophthalmological disorders (arteriosclerotic and hypertensive retinopathy);
• prophylaxis of diseases whose etiology is associated with oxidative stress.

2. Important information before using Vitaminum E 400 mg Hasco

When not to use Vitaminum E 400 mg Hasco

• if the patient is allergic to the active substance (vitamin E) or any of the other ingredients of this medicine (listed in section 6);
• if the patient is allergic to peanuts or soy;
• in case of vitamin K deficiency.

Warnings and precautions

Before starting to use Vitaminum E 400 mg Hasco, the patient should discuss it with their doctor, pharmacist, or nurse.
Particular caution should be exercised when using Vitaminum E 400 mg Hasco in patients who are also taking oral anticoagulant medicines (e.g., dicumarol, warfarin) or estrogens (e.g., oral contraceptives).

Vitaminum E 400 mg Hasco and other medicines

The patient should inform their doctor or pharmacist about all medicines they are currently taking or have recently taken, as well as any medicines they plan to take.
Vitamin E may act antagonistically to vitamin K, especially in patients treated with oral anticoagulant medicines or estrogens. The use of other antioxidants (vitamin C, selenium, ubiquinone, sulfur-containing amino acids) may alleviate some symptoms of vitamin E deficiency. Concurrent use of iron preparations may weaken the effect of vitamin E, so a few hours' interval should be maintained between taking these medicines.
Vitamin E may reduce the need for insulin and digitalis glycosides, and increase the absorption, utilization, and storage of vitamin A.

Pregnancy and breastfeeding

If the patient is pregnant or breastfeeding, thinks they may be pregnant, or plans to have a child, they should consult their doctor or pharmacist before using this medicine.
During pregnancy or breastfeeding, the medicine should only be used on the advice of a doctor.

Driving and operating machinery

Taking Vitaminum E 400 mg Hasco has no effect or a negligible effect on the ability to drive and operate machinery.

Vitaminum E 400 mg Hasco contains purified peanut oil.

If the patient is allergic to peanuts or soy, they should not use this medicine.

3. How to use Vitaminum E 400 mg Hasco

This medicine should always be used in accordance with the doctor's or pharmacist's recommendations. In case of doubts, the patient should consult their doctor or pharmacist.
The medicine is taken orally.
The recommended dose is usually 1 capsule per day.

Using a higher dose of Vitaminum E 400 mg Hasco than recommended

In case of taking a significantly higher dose of the medicine than recommended, the patient should consult their doctor or pharmacist.
High doses of vitamin E taken for a long time may cause diarrhea, abdominal pain, and other gastrointestinal disorders, as well as fatigue, weakness, blurred vision, headaches, rash, disorders of the sex glands, and decreased thyroid hormone levels in the blood.

Missing a dose of Vitaminum E 400 mg Hasco

The patient should not take a double dose to make up for a missed dose.

4. Possible side effects

Like all medicines, Vitaminum E 400 mg Hasco can cause side effects, although not everybody gets them.
Vitamin E is generally well-tolerated. After high doses (above 800 mg/day), it may cause fatigue, weakness, headaches, gastrointestinal disorders, or rash.

Reporting side effects

If the patient experiences any side effects, including any side effects not listed in this leaflet, they should inform their doctor, pharmacist, or nurse. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products: Al. Jerozolimskie 181C, 02-222 Warsaw, tel.: 22 49 21 301, fax: 22 49 21 309, e-mail: ndl@urpl.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help to gather more information on the safety of the medicine.

5. How to store Vitaminum E 400 mg Hasco

The medicine should be stored out of sight and reach of children.
Store in a temperature below 25°C.
Store in the original packaging to protect from light.
Do not use the medicine after the expiry date stated on the packaging. The expiry date refers to the last day of the specified month.
Medicines should not be disposed of via wastewater or household waste. The patient should ask their pharmacist how to dispose of medicines they no longer need. This will help protect the environment.

6. Contents of the packaging and other information

What Vitaminum E 400 mg Hasco contains

• The active substance of the medicine is all-rac-α-tocopheryl acetate (vitamin E). 1 soft capsule contains 400 mg of vitamin E.
• The other ingredients (excipients) are: purified peanut oil, gelatin, glycerol.

What Vitaminum E 400 mg Hasco looks like and what the packaging contains

Vitaminum E 400 mg Hasco is an oval, transparent capsule of light yellow color with a smooth, shiny surface.
One packaging of the medicine contains 30 soft capsules.

Marketing authorization holder and manufacturer

“PRZEDSIĘBIORSTWO PRODUKCJI FARMACEUTYCZNEJ HASCO-LEK” S.A.
51-131 Wrocław, ul. Żmigrodzka 242 E

Medicine information

tel.: 22 742 00 22
email: informacjaoleku@hasco-lek.pl

Date of last update of the leaflet: