TRASYLOL 277.8 Ph. Eur. units (500,000 KIU) Solution

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
€86
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Trasilol

Contents of the leaflet

  1. Package Leaflet: Information for the Patient
  2. TRASYLOL
    1. Read the package leaflet carefully before receiving this medicine, as it contains important information for you.
    2. Table of Contents of the Leaflet:
  3. What is Trasylol and what is it used for
  4. Important information before receiving Trasylol
    1. When you must not receive Trasylol
    2. Warnings and precautions
    3. Before receiving Trasylol, tell your doctor.
    4. Children and adolescents
    5. Trasylol and other medicines
    6. Pregnancy and breastfeeding
  5. How to use Trasylol
    1. Overdose of Trasylol
  6. Possible side effects
    1. Reporting of side effects
  7. How to store Trasylol
  8. Contents of the pack and other information
    1. What Trasylol contains
    2. What Trasylol looks like and contents of the pack
    3. Marketing authorization holder and manufacturer
    4. Marketing authorization holder
    5. Manufacturer
    6. Manufacturer
    7. Date of last revision of the leaflet:

Package Leaflet: Information for the Patient

TRASYLOL

(Aprotinin)
277.8 Ph. Eur. units (500,000 KIU), solution for infusion

Read the package leaflet carefully before receiving this medicine, as it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor/surgeon.
  • If you experience any side effects, including any not listed in this leaflet, tell your doctor. See section 4.

Table of Contents of the Leaflet:

  • 1. What is Trasylol and what is it used for
  • 2. Important information before receiving Trasylol
  • 3. How to use Trasylol
  • 4. Possible side effects
  • 5. How to store Trasylol
  • 6. Contents of the pack and other information
Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

1. What is Trasylol and what is it used for

Trasylol contains the active substance aprotinin. Trasylol belongs to a group of medicines called antifibrinolytics, i.e., medicines used to prevent blood loss.
Trasylol can help reduce blood loss during and after heart surgery. It may also be used to reduce the need for blood transfusions during and after heart surgery. Your doctor/surgeon will decide if you can benefit from Trasylol treatment, especially if you are at high risk of significant blood loss and are to undergo coronary artery bypass grafting using cardiopulmonary bypass (heart-lung machine).
Your doctor will administer aprotinin after careful consideration of the benefits and risks and the availability of alternative treatments.

2. Important information before receiving Trasylol

When you must not receive Trasylol

  • if you are allergic to aprotinin or any of the other ingredients of this medicine (listed in section 6).
  • if you have tested positive for aprotinin-specific IgG antibodies, indicating an increased risk of an allergic reaction to Trasylol.
  • if it is not possible to perform a test for aprotinin-specific IgG antibodies before starting treatment, and there is a suspicion that you have been exposed to Trasylol in the last 12 months.

Warnings and precautions

Before receiving Trasylol, tell your doctor.

Tell your doctor if any of the following apply to you, to help them decide if Trasylol is suitable for you:

  • -if you have kidney problems.If you have kidney problems, Trasylol should only be used if your doctor/surgeon thinks it will be beneficial for you.
  • -if you have received or suspect you have received aprotinin or tissue adhesives containing aprotinin in the last 12 months.

If any of the above apply to you, your doctor will decide if Trasylol is suitable for you.
Trasylol will only be given if your doctor performs blood tests beforehandto check that you can receive the medicine (e.g., a test for aprotinin-specific IgG antibodies), otherwise, other medicines may be a better alternative for you.
You will be closely monitored for a possible allergic reaction to Trasyloland your doctor/surgeon will treat any symptoms that may occur. During Trasylol treatment, emergency therapy should be available in case of severe allergic reactions.

Children and adolescents

The safety and efficacy of Trasylol in children under 18 years have not been established.

Trasylol and other medicines

Tell your doctor about all medicines you are taking or have recently taken, and any medicines you plan to take.
In particular, tell your doctor if you are taking:

  • medicines used to dissolve blood clots, such as streptokinase, urokinase, alteplase (r-tPA)
  • aminoglycosides (antibiotics, medicines used to treat infections)

It is recommended that your doctor/surgeon administers heparin (a medicine used to prevent blood clots) before and during surgery, in addition to Trasylol. Your doctor will assess the heparin dose based on blood test results.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to have a child, ask your doctor for advice before taking this medicine. If you are pregnant or breastfeeding, Trasylol should only be used if your doctor/surgeon thinks it will be beneficial for you. Your doctor will discuss the possible risks and benefits of using this medicine.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

3. How to use Trasylol

For adult patients, the recommended dosing regimen is:
You will receive a small amount of Trasylol (1 ml) before the start of surgery to check if you are allergic to Trasylol. Medicines used to prevent allergic symptoms (H1 and H2 antagonists) may be given 15 minutes before the Trasylol test dose.
If no allergic symptoms occur, you will receive 100-200 ml of Trasylol over 20 to 30 minutes, followed by 25-50 ml per hour (max. 5-10 ml/min) until the end of surgery.
Usually, you will not receive more than 700 ml of Trasylol at any time.
There are no special recommendations for dosing in elderly patients or patients with impaired renal function.
Trasylol will usually be given to you while you are lying down, as a slow injection or infusion (in a "drip") through a central venous catheter in your body.

Overdose of Trasylol

There is no specific antidote to reverse the effects of Trasylol.
If you have any further questions on the use of this medicine, ask your doctor.

4. Possible side effects

Like all medicines, Trasylol can cause side effects, although not everybody gets them.
Although allergic reactions are rare in patients receiving Trasylol for the first time, patients who receive Trasylol more than once may have a higher risk of an allergic reaction. Symptoms of an allergic reaction may include:

  • difficulty breathing
  • low blood pressure
  • itching, rash, and hives
  • nausea

If any of these symptoms occur during Trasylol administration, your doctor/surgeon will stop the treatment.
Other side effects include:
Common:may affect up to 1 in 10 people

  • abnormal kidney function test results (increased creatinine levels)

Uncommon:may affect up to 1 in 100 people

  • chest pain [myocardial ischemia, coronary artery occlusion], heart attack (myocardial infarction)
  • fluid accumulation in the sac surrounding the heart (pericardial effusion)
  • blood clots (thrombosis)
  • reduced or interrupted blood flow to the brain (stroke)
  • kidney disease (acute kidney injury, renal tubular necrosis)
  • passing less urine than usual
  • severe allergic reaction (anaphylactic or anaphylactoid reaction)

Rare:may affect up to 1 in 1,000 people

  • blood clots in the blood vessels (arterial thrombosis)
  • blood clots in the lungs (pulmonary embolism)

Very rare:may affect up to 1 in 10,000 people

  • swelling at the injection site or around the injection site on the skin (injection site and infusion reactions), thrombophlebitis (infusion site)
  • -severe disorder of blood clotting leading to tissue damage and bleeding (disseminated intravascular coagulation)
  • -inability of blood to clot or coagulate properly (coagulopathy)
  • -severe life-threatening allergic shock (anaphylactic shock)

Reporting of side effects

If you experience any side effects, including any not listed in this leaflet, tell your doctor. Side effects can be reported directly to the Department of Drug Safety Monitoring of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products, Al. Jerozolimskie 181 C, 02-222 Warsaw, Tel.: +48 22 49 21 301, Fax: +48 22 49 21 309, Website: https://smz.ezdrowie.gov.pl.
Side effects can also be reported to the marketing authorization holder.
By reporting side effects, you can help provide more information on the safety of this medicine.

5. How to store Trasylol

Keep out of the sight and reach of children.
Do not use this medicine after the expiry date stated on the carton and bottle after "Expiry Date (EXP)". The expiry date refers to the last day of the month.
Store below 25°C. Store in the original package to protect from light.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

What Trasylol contains

50 ml of the solution for infusion contains:

  • the active substance is a concentrated solution of aprotinin with an activity of 277.8 Ph. Eur. units, equivalent to 500,000 KIU (kallikrein inactivation units).
  • the other ingredients are sodium chloride, water for injections.

What Trasylol looks like and contents of the pack

Trasylol is a clear, colorless solution for infusion.
The pack contains 1 glass vial containing 50 ml of the solution, closed with a siliconized rubber stopper and an aluminum cap with a flip-off seal, in a cardboard box.

Marketing authorization holder and manufacturer

Marketing authorization holder

Nordic Group B.V.
Siriusdreef 41
2132 WT Hoofddorp
Netherlands

Manufacturer

Fresenius Kabi Austria GmbH
Hafnerstrasse 36
8055 Graz
Austria

Manufacturer

Apotek Produktion & Laboratorier AB (APL)
Formvägen 5B
906 21 Umeå
Sweden
To obtain more detailed information, contact the local representative of the marketing authorization holder:
AMRING FARMA SRL
Tel.: +40 31 620 1204
[email protected]

Date of last revision of the leaflet:

Online doctors for Trasilol

Discuss questions about Trasilol, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
€86
Doctor
5.0(19)

Nuno Tavares Lopes

Family medicineGeneral medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70
Doctor
0.0(0)

Hocine Lokchiri

General medicine21 years of experience

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Book a video appointment
€64
Doctor
0.0(0)

Muhammad Tayyab Altaf

General medicine3 years of experience

Dr. Muhammad Tayyab Altaf is a primary care physician with extensive international experience, offering online consultations for adults and children. His background includes clinical practice in Policlinico San Matteo Hospital Pavia in Italy, Mount Sinai Hospital in New York, United States and other healthcare settings, allowing him to manage a wide range of acute and chronic medical conditions with confidence and clarity.

His clinical expertise spans multi-system conditions, preventive care and long-term management of chronic diseases. Dr. Altaf combines hands-on experience with a strong research background in both medical and surgical fields, enabling him to provide accurate assessments and structured, evidence-based treatment plans. Patients value his ability to explain diagnoses clearly, outline next steps and support them in making informed healthcare decisions.

Online consultations with Dr. Altaf are suitable for many everyday and acute situations where a timely medical opinion can help determine the safest next steps. He evaluates and treats conditions affecting the cardiovascular, respiratory, gastrointestinal, neurological, haematological and endocrine systems. Common examples include:

  • hypertension and other blood pressure issues
  • ischaemic heart disease and angina
  • asthma, COPD and emphysema
  • pneumonia and lung fibrosis
  • gastroenteritis and digestive infections
  • liver conditions, including alcohol-related disease
  • epilepsy, seizures and post-stroke symptoms
  • dementia and cognitive decline
  • anaemia and other haematological changes
  • diabetes, thyroid disorders and pituitary disease
Many patients reach out when they experience new or worsening symptoms, fluctuations in blood pressure, non-severe chest discomfort, breathing symptoms, digestive issues, suspected infections, chronic fatigue or concerns that affect daily life. He also helps patients understand test results, adjust existing treatment plans and navigate long-term health strategies safely and effectively.

When clinically appropriate, Dr. Altaf can also provide health and fitness certificates, including documentation required for physical activity, sports participation or gym use, based on the patient’s health status and medical indications.

Some conditions are not suitable for online care. Severe chest pain, loss of consciousness, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack require immediate attention from local emergency services. Dr. Altaf prioritises patient safety and will guide you accordingly if your situation needs urgent in-person care.

In all consultations, Dr. Muhammad Tayyab Altaf focuses on clear communication, accurate diagnosis and patient-centred decision-making. His approach ensures that individuals and families feel informed, supported and confident in their next steps, no matter where they are.

Book a video appointment
€71

Get Trasilol Prescription Online

1

Fill in a 2-min form

Tell us your symptoms, history, and what medicine you're requesting.

2

Pick a doctor or let us assign

Choose a specialist or we'll match you with the next available doctor.

3

Doctor reviews your case

Usually within 30 minutes. They may ask follow-up questions via chat.

4

Collect from any pharmacy

Electronic prescription sent to your email — valid across Spain.

Frequently Asked Questions

Is a prescription required for Trasilol?

Trasilol does not require a prescription in Poland. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in Trasilol?

The active ingredient in Trasilol is aprotinin. This information helps identify medicines with the same composition but different brand names.

Who manufactures Trasilol?

Trasilol is manufactured by Apotek Produktion & Laboratorier AB (APL) Fresenius Kabi Austria GmbH. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of Trasilol online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether Trasilol is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy Trasilol in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy Trasilol in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to Trasilol?

Other medicines with the same active substance (aprotinin) include Rimphisia, Rimphisia, Deporium Comfort. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media