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Tokovit A + E

Tokovit A + E

Ask a doctor about a prescription for Tokovit A + E

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Tokovit A + E

1. What is TOKOVIT A + E and what is it used for

Vitamin A plays an essential role in the process of vision (ensuring proper functioning of the retina), is necessary for growth, regeneration, differentiation, and function of epithelial tissue, skin, and mucous membranes. It participates in bone calcification and structure formation, in the reproductive process, and in embryonic development of the fetus.
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Vitamin E is a substance obtained from natural plant oils, necessary for the proper functioning of the body. It exhibits biological activity 50% stronger than commonly used synthetic vitamin.
Epidemiological studies indicate a correlation between daily intake of vitamin E and the risk of coronary heart disease, carotid atherosclerosis, and other diseases whose etiology is associated with oxidative stress.
The medicine TOKOVIT A + E is intended for the prevention and supplementation of vitamins A and E:

  • during periods of increased demand for these vitamins,
  • to prevent certain skin conditions, such as keratosis pilaris,
  • to prevent deficiencies that may lead to growth and development disorders, pathological changes in epithelial and mucous membranes, and night blindness,
  • to reduce the effects of stress (due to antioxidant properties),
  • with increased physical exertion,
  • with an elimination diet,
  • in people living in a polluted environment and smokers.

2. Before taking TOKOVIT A + E

Do not take TOKOVIT A + E if:

  • you are hypersensitive to any component of the medicine,
  • you have a vitamin K deficiency,
  • you have an overdose of vitamin A (so-called hypervitaminosis A),
  • you have severe hypertension, glaucoma, or myasthenia gravis.

Special precautions when taking TOKOVIT A + E

  • in patients with liver diseases (liver cirrhosis, viral hepatitis) who require lower doses prescribed by a doctor,
  • when taking other medicines containing vitamin A, due to the possibility of its overdose,
  • in patients taking oral anticoagulants or estrogens (e.g., oral contraceptives) at the same time. The absorption of vitamin A is reduced in case of impaired fat absorption and low protein intake. You should consult a doctor, even if the above warnings concern situations that occurred in the past.

Pregnancy

Before taking the medicine, consult a doctor.
Pregnant women can take TOKOVIT A + E only after consulting a doctor and in the doses prescribed by them, as taking increased amounts of vitamin A can be hazardous to the fetus.
Taking high doses of vitamin E during pregnancy is not recommended due to the lack of data on the safety of its use.

Breastfeeding

Before taking the medicine, consult a doctor.
Vitamin A passes into breast milk, which can lead to its overdose in the child. Breastfeeding women can take TOKOVIT A + E only after consulting a doctor and in the doses prescribed by them, as taking increased amounts of vitamin A can be hazardous to the child.
Taking high doses of vitamin E during breastfeeding is not recommended due to the lack of data on the safety of its use.

Driving and operating machinery

Taking TOKOVIT A + E does not affect the ability to drive vehicles and operate machinery.

Important information about some components of TOKOVIT A + E

The medicine contains peanut oil (from peanuts). If you are allergic to peanuts or soy, do not take this medicine.

Using other medicines

Tell your doctor about all the medicines you have taken recently, even those that are available
without a prescription.
Neomycin, cholestyramine (colestipol), and liquid paraffin reduce the absorption of vitamin A. Concurrent use of products containing vitamin A (carotenes), synthetic analogs of vitamin A (acitretin, etretinate, tretinoin), and bexarotene may lead to the occurrence of hypervitaminosis A symptoms. Vitamin A, when administered in doses several times higher than recommended, enhances the effect of anticoagulant medicines (warfarin derivatives). Oral contraceptives may increase the concentration of vitamin A in the blood.
Vitamin E may act antagonistically to vitamin K, especially in people treated with oral anticoagulants or estrogens. The use of other agents with antioxidant activity (vitamin C, selenium, ubiquinone, sulfur-containing amino acids) may alleviate some symptoms of vitamin E deficiency. Concurrent use of iron preparations weakens the effect of vitamin E, so it is recommended to maintain a few-hour interval between taking these medicines. Vitamin E may reduce the need for insulin and digitalis glycosides.

3. How to take TOKOVIT A + E

The medicine is intended for oral use.
For prophylaxis, unless otherwise prescribed by a doctor, usually 1 or 2 capsules are taken during the first meal, for adolescents and adults.
Therapeutically: according to the doctor's instructions, depending on the degree of deficiency.
If you feel that the effect of TOKOVIT A + E is too strong or too weak, consult a doctor.

In case of taking a higher dose of TOKOVIT A + E than recommended

In case of taking a significantly higher dose of the medicine than recommended, consult a doctor or
pharmacist.
Symptoms of acute vitamin A poisoning may occur in children after taking 75,000 to 350,000 IU, and in adults after taking a dose of 1,000,000 IU. Characteristic symptoms of vitamin A overdose are headaches, nausea, vomiting, auditory hallucinations, vision disturbances, swelling of subcutaneous tissue and tissues around long bones, muscle-bone-joint pain, skin and mucous membrane symptoms. Additionally, hypercalcemia, petechiae, bleeding, nervousness, fatigue, irritability, and drowsiness have been observed. Very significant and prolonged overdose of vitamin A may be accompanied by other adverse symptoms related to the cardiovascular system, central nervous system, gingivitis, liver damage symptoms, respiratory function disorders, dermatological changes, and skin discoloration, osteoporosis, bone hardening, and other changes considered less specific.
High doses of vitamin E (400 to 800 IU per day) taken for a longer period may cause diarrhea, abdominal pain, and other gastrointestinal disorders, as well as fatigue, weakness, blurred vision, headaches, rash, disorders of sexual gland function, and decreased levels of thyroid hormones in the blood.
In case of overdose symptoms, it is necessary to stop taking the product and consult a doctor.

In case of missing a dose of TOKOVIT A + E

Do not take a double dose to make up for the missed dose.

4. Possible side effects

Like any medicine, TOKOVIT A + E can cause side effects.
Vitamins A and E are generally well-tolerated, and their intake in recommended doses is not associated with a significant risk of side effects. Symptoms of side effects are related to the overdose of the product (see section 3).
In some people, other side effects may occur during the use of the medicine. If other side effects occur that are not listed in this leaflet, inform your doctor about them.

5. Storage of TOKOVIT A + E

Keep the medicine out of sight and reach of children.
Do not use TOKOVIT A + E after the expiration date stated on the packaging.
Store in the original packaging, at a temperature below 25°C.

6. Other information

To obtain more detailed information, contact the representative of the responsible entity:
“HASCO-LEK” Pharmaceutical Production Company S.A.
51-131 Wrocław, ul. Żmigrodzka 242 E
tel. (071) 352 95 22
fax (071) 352 76 36
Drug Information Department
tel. (22) 742 00 22
email: [email protected]
Date of leaflet preparation:
4/4

Alternatives to Tokovit A + E in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Tokovit A + E in Ukraine

Dosage form: capsules, 10 capsules in a blister
Dosage form: capsules, 10 capsules in a blister
Prescription not required
Dosage form: capsules, 10 capsules in blisters
Prescription not required

Alternative to Tokovit A + E in Spain

Dosage form: CAPSULE, 5000 IU Vitamin A + 10 mg Vitamin E
Manufacturer: Chiesi España S.A.U.
Prescription not required

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