ACIDUM 100 mg /Ml Solution
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Contents of the leaflet
- Leaflet attached to the packaging: patient information
- Warning! The leaflet should be kept. Information on the immediate packaging in a foreign language.
- Acidum ascorbicum Delfarma, 100 mg/ml, solution for injection
- What is Acidum ascorbicum Delfarma and what is it used for
- Important information before using Acidum ascorbicum Delfarma
- How to use Acidum ascorbicum Delfarma
- Possible side effects
- How to store Acidum ascorbicum Delfarma
- Contents of the packaging and other information
Leaflet attached to the packaging: patient information
Warning! The leaflet should be kept. Information on the immediate packaging in a foreign language.
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Discuss your symptoms and treatment with a doctor online.
Acidum ascorbicum Delfarma, 100 mg/ml, solution for injection
Acidum ascorbicum
You should carefully read the contents of the leaflet before using the medicine, as it contains important information for the patient.
- You should keep this leaflet, so that you can read it again if you need to.
- If you have any doubts, you should consult a doctor, pharmacist, or nurse.
- This medicine has been prescribed specifically for you. Do not pass it on to others. The medicine may harm another person, even if their symptoms are the same.
- If the patient experiences any side effects, including any side effects not listed in this leaflet, they should tell their doctor, pharmacist, or nurse. See section 4.
Table of contents of the leaflet
- 1. What is Acidum ascorbicum Delfarma and what is it used for
- 2. Important information before using Acidum ascorbicum Delfarma
- 3. How to use Acidum ascorbicum Delfarma
- 4. Possible side effects
- 5. How to store Acidum ascorbicum Delfarma
- 6. Contents of the packaging and other information
1. What is Acidum ascorbicum Delfarma and what is it used for
The active substance of the medicine is ascorbic acid, i.e., vitamin C, which belongs to water-soluble vitamins. It participates in the production of collagen and intercellular substance and is therefore necessary for the proper development of cartilage, bones, teeth, as well as for wound healing. It also plays a very important role in the conversion of folic acid to folinic acid, facilitates the absorption of iron from the digestive tract, and participates in the production of hemoglobin and the maturation of erythrocytes (red blood cells).
The indication for the use of the medicine is:
- treatment of scurvy and other states of deficiency requiring vitamin C supplementation. The medicine in the form of a parenteral solution is administered in severe cases or when oral administration is difficult.
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2. Important information before using Acidum ascorbicum Delfarma
When not to use Acidum ascorbicum Delfarma:
- if the patient is allergic to vitamin C or any of the other ingredients of this medicine (listed in section 6);
- in kidney stones (oxalate).
Warnings and precautions
Particular caution should be exercised when using Acidum ascorbicum Delfarmain the following cases:
- excessive amounts of oxalic acid or oxalates in the urine,
- tendency to form mineral deposits in the urinary system,
- hemochromatosis (a congenital metabolic disorder characterized by the deposition of iron in tissues),
- diabetes,
- thalassemia (a hemolytic anemia),
- sideroblastic anemia, Page 1 5
- glucose-6-phosphate dehydrogenase deficiency, as high doses of vitamin C may then cause red blood cell breakdown.
In patients taking high doses, tolerance to ascorbic acid may develop.
Vitamin C used in high doses (from 1 g per day) may falsify the results of some laboratory tests performed using oxidation-reduction methods (e.g., glucose concentration in urine, ethinylestradiol concentration in serum, lactic dehydrogenase activity, liver transaminases in serum, occult blood test in stool, bilirubin concentration, urine pH, uric acid and oxalate content in urine, iron and ferritin concentration in serum).
High doses of vitamin C may weaken the effect of oral anticoagulant drugs.
During concurrent administration with ascorbic acid, the concentration of flufenazine (a drug used, among others, in schizophrenia) in serum may decrease.
Ascorbic acid administered as an auxiliary agent with deferoxamine in patients who have taken an overdose of iron (in order to better eliminate it) may increase its toxic effect, especially on the heart muscle, especially in the early stages of treatment, when the amount of iron in tissues is excessive. Therefore, such a combination should not be used in patients with impaired heart function, while in patients with normal heart function, the doctor will use vitamin C no earlier than after a month from the start of deferoxamine treatment.
In patients with impaired renal function using antacids containing aluminum and oral citrates, life-threatening encephalopathy may develop, caused by a significant increase in aluminum concentrations in the blood. There are suspicions that vitamin C may interact similarly.
Oral contraceptives reduce the concentration of ascorbic acid in serum. Concurrent use of these agents with vitamin C may result in increased estradiol concentration in serum.
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Incompatibilities with other medicines
Vitamin C is incompatible with iron salts, oxidizing agents, and heavy metal salts, especially copper.
Incompatibilities of the vitamin C solution have been reported with: aminophylline, bleomycin sulfate, cefazolin (sodium salt), cefapirin, chlordiazepoxide, conjugated estrogens, dextran, doxapram (hydrochloride), erythromycin lactobionate, methicillin (sodium salt), nafcillin (sodium salt), nitrofurantoin (sodium salt), sulfafurazole diethanolamine, penicillin G (potassium salt), phytomenadione, sodium bicarbonate, warfarin.
Occasionally, depending on the pH and concentration, incompatibility with sodium succinate chloramphenicol may occur.
Acidum ascorbicum Delfarma contains sodium metabisulfite and sodium
Sodium metabisulfite
The medicine may rarely cause severe hypersensitivity reactions and bronchospasm.
Sodium
The medicine contains more than 1 mmol (23 mg) of sodium (the main component of table salt) per dose.
3. How to use Acidum ascorbicum Delfarma
This medicine should always be used in accordance with the doctor's recommendations. In case of doubts, you should consult a doctor.
The medicine is used in the form of intramuscular or intravenous injections.
The doctor will determine the dosage individually, depending on the vitamin C deficiency assessed on the basis of symptoms.
Adults:
therapeutically:from 500 mg to 1000 mg per day, in divided doses;
Children:
therapeutically:from 100 mg to 300 mg per day in 2-3 divided doses.
If you feel that the effect of Acidum ascorbicum Delfarma is too strong or too weak, you should consult a doctor.
Using a higher dose of Acidum ascorbicum Delfarma than recommended:
Symptoms of vitamin C overdose may include gastrointestinal disorders, including diarrhea, vomiting, heartburn, as well as skin redness, headache, and insomnia. High doses may cause excessive excretion of oxalic acid in the urine and the formation of oxalate stones in the kidneys. Daily doses of 600 mg and higher may have a diuretic effect.
In case of overdose symptoms, the administration of the medicine should be discontinued, and the doctor will use symptomatic treatment.
In case of taking a higher dose of the medicine than recommended, you should immediately consult a doctor or pharmacist.
Missing a dose of Acidum ascorbicum Delfarma
You should take the prescribed dose as soon as possible.
You should not take a double dose to make up for the missed dose.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
High doses of vitamin C may cause stomach and intestinal disorders, including diarrhea, vomiting, heartburn, skin redness, headache, and insomnia. High doses may also cause hyperoxaluria (increased excretion of oxalic acid in the urine) and the formation of kidney stones, if the urine becomes acidified. Daily doses of 600 mg and higher may have a diuretic effect.
Too rapid intravenous administration may cause dizziness and a feeling of weakness.
After long-term use of high doses, tolerance to ascorbic acid may develop, and in case of dose reduction, deficiency symptoms may occur.
Intramuscular administration may cause transient pain at the injection site.
In some people, during the use of Acidum ascorbicum Delfarma, other side effects may occur.
Reporting side effects
If you experience any side effects, including any side effects not listed in this leaflet, you should tell your doctor, pharmacist, or nurse. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products
Al. Jerozolimskie 181C
02-222 Warsaw
Phone: + 48 22 49 21 301
Fax: + 48 22 49 21 309
Website: https://smz.ezdrowie.gov.pl
By reporting side effects, you can help gather more information on the safety of the medicine.
5. How to store Acidum ascorbicum Delfarma
The medicine should be stored out of sight and reach of children.
Store in a temperature below 25°C.
Store in the original packaging to protect from light.
The solution should be used immediately after opening the ampoule. The unused amount of the solution should be discarded.
Do not use this medicine after the expiry date stated on the packaging. The expiry date is the last day of the specified month.
Medicines should not be disposed of via wastewater or household waste containers. You should ask your pharmacist how to dispose of medicines that are no longer needed. This will help protect the environment.
6. Contents of the packaging and other information
What Acidum ascorbicum Delfarma contains
- The active substance of the medicine is ascorbic acid. 1 ml of the solution contains 100 mg of ascorbic acid. 1 ampoule with a capacity of 5 ml contains 500 mg of ascorbic acid (100 mg/ml).
- Excipients: sodium hydroxide, sodium metabisulfite, water for injections.
What Acidum ascorbicum Delfarma looks like and what the packaging contains
Acidum ascorbicum Delfarma, 100 mg/ml, solution for injection is a colorless or slightly yellowish, clear liquid.
The medicine is packaged in brown glass ampoules with a capacity of 5 ml (500 mg/5 ml), 5 pieces in a cardboard box.
To obtain more detailed information, you should contact the marketing authorization holder or the parallel importer.
Marketing authorization holder in Italy, the country of export:
S.A.L.F. S.p.A. Laboratorio Farmacologico, Via Marconi, 2 – 24069 Cenate Sotto (BG), Italy
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Manufacturer:
S.A.L.F. S.p.A. Laboratorio Farmacologico, Via Marconi, 2 – 24069 Cenate Sotto (BG), Italy
Parallel importer:
Delfarma Sp. z o.o., ul. Św. Teresy od Dzieciątka Jezus 111, 91-222 Łódź
Repackaged by:
Delfarma Sp. z o.o., ul. Św. Teresy od Dzieciątka Jezus 111, 91-222 Łódź
Italian, country of export marketing authorization number: 008194045
Parallel import authorization number: 195/24
Leaflet approval date: 09.05.2024
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- Country of registration
- Dosage formSolution, 100 mg/ml
- ATC codeA11GA01
- Active substance
- Prescription requiredYes
- Marketing authorisation holder (MAH)S.A.L.F. S.p.A. Laboratorio Farmacologico
- This information is for reference only and does not constitute medical advice. Always consult a doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
- Alternatives to Acidum ascorbicum DelfarmaDosage form: Solution, 100 mg/mlActive substance: ascorbic acid (vit C)Prescription requiredDosage form: Drops, 100 mg/mlActive substance: ascorbic acid (vit C)Prescription not requiredDosage form: Tablets, 1000 mgActive substance: ascorbic acid (vit C)Manufacturer: N.P. Pharma Sp. z o.o.Prescription not required
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Frequently Asked Questions
Acidum ascorbicum Delfarma requires a prescription in Poland. You can check with a doctor online whether this medicine may be appropriate for your situation.
The active ingredient in Acidum ascorbicum Delfarma is ascorbic acid (vit C). This information helps identify medicines with the same composition but different brand names.
Acidum ascorbicum Delfarma is manufactured by S.A.L.F. S.p.A. Laboratorio Farmacologico. Pharmacy brands and packaging may differ depending on the distributor.
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether Acidum ascorbicum Delfarma is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.
You can buy Acidum ascorbicum Delfarma in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.
To obtain a prescription, you can use Oladoctor:
Other medicines with the same active substance (ascorbic acid (vit C)) include Acidum ascorbicum Aga Kommezh, Ascorgem, Ascorvita. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
