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Silimarol Plus

Ask a doctor about a prescription for Silimarol Plus

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Silimarol Plus

Leaflet attached to the packaging: patient information

SYLIMAROL PLUS

Silymaryno-phospholipid complex
coated tablets
100 mg

Read the leaflet carefully before taking the medicine, as it contains important information for the patient.

This medicine should always be taken exactly as described in the patient leaflet or as directed by a doctor, pharmacist, or nurse.

  • Keep this leaflet, you may need to read it again.
  • If you need advice or additional information, consult a pharmacist.
  • If the patient experiences any side effects, including any possible side effects not listed in the leaflet, tell your doctor, pharmacist, or nurse. See section 4.
  • If there is no improvement or the patient feels worse, contact a doctor.

Table of contents of the leaflet:

  • 1. What is Sylimarol Plus and what is it used for
  • 2. Important information before taking Sylimarol Plus
  • 3. How to take Sylimarol Plus
  • 4. Possible side effects
  • 5. How to store Sylimarol Plus
  • 6. Package contents and other information

1. What is Sylimarol Plus and what is it used for

Sylimarol Plus contains a silymaryno-phospholipid complex with a 30% content of flavonolignans calculated as silybin. It is used traditionally in proposed indications and its effectiveness is based solely on a long period of use and experience.

Indications:

The medicine is used as a supportive treatment in liver function disorders.

2. Important information before taking Sylimarol Plus

When not to take Sylimarol Plus:

  • if the patient is allergic to the active substances or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

In case of jaundice symptoms (yellowing of the skin or yellowing of the eyeball), consult a doctor.
If other symptoms worsen or do not improve, consult a doctor. The doctor may recommend continuing therapy.

Children and adolescents

No studies have been conducted on the safety of using the medicine in children and adolescents. It is not recommended to use the medicine in children under 12 years of age. In adolescents under 18 years of age, it can be used after prior consultation with a doctor.

Sylimarol Plus and other medicines

Tell your doctor or pharmacist about all medicines you are taking, or have recently taken, and about medicines you plan to take.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to have a child, consult a doctor or pharmacist before taking this medicine.
Due to the lack of data confirming safety, it is not recommended to use the preparation during pregnancy and breastfeeding.

Driving and using machines

The effect on the ability to drive and use machines has not been studied.

3. How to take Sylimarol Plus

This medicine should always be taken exactly as described in the patient leaflet or as directed by a doctor, pharmacist, or nurse. In case of doubts, consult a doctor or pharmacist.
Usually, the recommended dose for adults is: 1 tablet 3 times a day in chronic diseases; 2 tablets 3 times a day in acute conditions, unless the doctor recommends otherwise.
The medicine should be taken after eating.

Taking a higher dose of Sylimarol Plus than recommended

There are no reports of overdose.

Missing a dose of Sylimarol Plus

Do not take a double dose to make up for a missed dose.

Stopping Sylimarol Plus treatment

In case of further doubts about taking this medicine, consult a doctor, pharmacist, or nurse.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
So far, no side effects of Sylimarol Plus have been reported.
During use, gastrointestinal disorders are possible. Mild laxative effects may occur occasionally.

Reporting suspected side effects

If you experience any side effects, including any side effects not listed in the leaflet, tell your doctor, pharmacist, or nurse. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products, Al. Jerozolimskie 181C, 02-222 Warsaw, tel. 48 22 49 21 301, fax 48 22 49 21 309, website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help gather more information on the safety of the medicine.

5. How to store Sylimarol Plus

Keep the medicine out of sight and reach of children.
Store at a temperature not exceeding 25°C.
Do not use this medicine after the expiry date stated on the packaging. The expiry date refers to the last day of the given month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Package contents and other information

What Sylimarol Plus contains:1 tablet contains 100 mg of silymaryno-phospholipid complex with a 30% content of flavonolignans calculated as silybin and 1.5% phosphorus.
Other ingredients (excipients) are: microcrystalline cellulose with colloidal silicon dioxide 2%, sodium carmellose, hypromellose, macrogol 6000, titanium dioxide, indigo carmine lake (E 132), yellow quinoline lake (E 104).

What Sylimarol Plus looks like and what the package contains

Sylimarol Plus is available in the form of coated tablets. The package contains: 20 or 40 tablets in PVC/Al blisters in a cardboard box.
For more detailed information, consult the marketing authorization holder.

Marketing authorization holder and manufacturer

Poznańskie Zakłady Zielarskie Herbapol S.A.
ul. Towarowa 47/51, 61-896 Poznań, Poland
tel. + 48 61 886 18 00
Date of last update of the leaflet:…2025

Alternatives to Silimarol Plus in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Silimarol Plus in Spain

Dosage form: CAPSULE, 300 mg
Prescription not required
Dosage form: CAPSULE, 100 mg Dry extract of milk thistle (equivalent to 80 mg of silymarin)
Active substance: silymarin
Prescription required
Dosage form: INJECTABLE PERFUSION, 350 mg sodium silibinate
Prescription required
Dosage form: CAPSULE, 150 mg silymarin
Active substance: silymarin
Prescription required
Dosage form: TABLET, 4.6 mg dry extract Cynara scolimus (1:30-31); 1.2 mg dry extract Taraxacum officinalis (1:17-18); 0.7 mg dry extract Peumus boldus (1:10-11); 3.2 mg dry extract Silibum marianum (1:2-2.1)
Prescription not required
Dosage form: CAPSULE, 390 mg
Prescription not required

Alternative to Silimarol Plus in Ukraine

Dosage form: fruits, 50 g, or 100 g, or 200 g
Manufacturer: PRAT "FITOFARM
Prescription not required
Dosage form: fruits, 50 g, 100 g or 200 g
Prescription not required
Dosage form: lyophilizate, 1 vial (bottle) contains lecithin standard - 320 mg; anthral - 4.2 mg
Manufacturer: TOV "BIOLIK FARMA
Prescription required
Dosage form: capsules, 10 capsules in a blister
Prescription not required
Dosage form: solution, 50mg/ml in 5ml ampoule
Manufacturer: AT "Farmak
Prescription required
Dosage form: capsules, 10 capsules in a blister
Manufacturer: Nabros Farma Pvt. Ltd.
Prescription not required

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