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Papaverinum hidrohloricum Vzf

Papaverinum hidrohloricum Vzf

Ask a doctor about a prescription for Papaverinum hidrohloricum Vzf

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Doctor

Tarek Agami

General medicine10 years of experience

Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

  • Diagnosis and treatment of acute and chronic conditions (high blood pressure, diabetes, respiratory infections, cardiovascular symptoms)
  • Evaluation of symptoms and guidance on further diagnostic testing
  • Preventive check-ups and regular health monitoring
  • Medical support during travel or after relocation
  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Papaverinum hidrohloricum Vzf

Leaflet attached to the packaging: patient information

PAPAVERINUM HYDROCHLORICUM WZF, 20 mg/ml, solution for injections

Papaverine hydrochloride

Read the leaflet carefully before using the medicine, as it contains important information for the patient.

  • Keep this leaflet, so you can read it again if you need to.
  • If you have any doubts, consult your doctor or pharmacist.
  • This medicine has been prescribed specifically for you. Do not pass it on to others. The medicine may harm another person, even if their illness symptoms are the same.
  • If the patient experiences any side effects, including any side effects not listed in this leaflet, they should inform their doctor or pharmacist. See section 4.

Table of contents of the leaflet

  • 1. What is Papaverinum hydrochloricum WZF and what is it used for
  • 2. Important information before using Papaverinum hydrochloricum WZF
  • 3. How to use Papaverinum hydrochloricum WZF
  • 4. Possible side effects
  • 5. How to store Papaverinum hydrochloricum WZF
  • 6. Package contents and other information

1. What is Papaverinum hydrochloricum WZF and what is it used for

Papaverine belongs to the isoquinoline alkaloids of opium. It relaxes smooth muscles by directly affecting their cells. Papaverine does not have analgesic effects and does not lead to addiction.
The medicine is used in spastic conditions (muscle spasms) of:

  • the digestive tract - biliary colic, spastic conditions of the bile ducts, intestinal colic;
  • the urinary tract - renal colic, painful urination.

2. Important information before using Papaverinum hydrochloricum WZF

When not to use Papaverinum hydrochloricum WZF

  • if the patient is allergic to papaverine or any other component of the medicine (listed in section 6);
  • if the patient has conduction disorders in the heart muscle.

Warnings and precautions

Before starting to use Papaverinum hydrochloricum WZF, the patient should discuss it with their doctor, especially if they have:

  • glaucoma,
  • liver function disorders,
  • angina pectoris,
  • recently had a heart attack.

Children
Due to the lack of relevant clinical data, Papaverinum hydrochloricum WZF should not be used in children.

Papaverinum hydrochloricum WZF and other medicines

The patient should inform their doctor about all medicines they are currently taking or have recently taken, as well as any medicines they plan to take.
Papaverine weakens the effect of levodopa (a medicine used to treat Parkinson's disease).

Pregnancy and breastfeeding

If the patient is pregnant or breastfeeding, thinks they may be pregnant, or plans to have a child, they should consult their doctor or pharmacist before using this medicine.
The medicine contains benzyl alcohol - see below, section "Papaverinum hydrochloricum WZF contains benzyl alcohol and sodium."
The doctor will decide whether the medicine can be used.

Driving and operating machinery

The patient should be cautious, as the medicine may cause dizziness or drowsiness.

Papaverinum hydrochloricum WZF contains benzyl alcohol and sodium

The medicine contains 10 mg of benzyl alcohol in each ml of solution. Each ampoule (2 ml of solution) contains 20 mg of benzyl alcohol.
Benzyl alcohol may cause allergic reactions.
Administering benzyl alcohol to small children is associated with a risk of severe side effects, including breathing difficulties (so-called "gasping syndrome"). Papaverinum hydrochloricum WZF should not be used in children (see also section 3).
Pregnant or breastfeeding women, patients with liver or kidney diseases should consult their doctor before using the medicine, as a large amount of benzyl alcohol may accumulate in their body and cause side effects (so-called metabolic acidosis).
The medicine contains less than 1 mmol (23 mg) of sodium per ampoule (2 ml), which means the medicine is considered "sodium-free".

3. How to use Papaverinum hydrochloricum WZF

This medicine should always be used according to the doctor's recommendations. If you have any doubts, consult your doctor or pharmacist.
Adults
Administer intramuscularly or subcutaneously, without dilution:
from 40 mg to 120 mg (from 2 ml to 6 ml, i.e., 1 to 3 ampoules). If necessary, the dose may be repeated after 3 hours, up to 4 times a day.
Children
Papaverinum hydrochloricum WZF should not be used in children.

Instructions for opening the ampoule

Before opening the ampoule, make sure the entire solution is in the lower part of the ampoule.
You can gently shake the ampoule or tap it with your finger to help the solution flow down.
A colored dot is marked on each ampoule (see Figure 1) as a sign of the break point located below it.

  • To open the ampoule, hold it vertically, with both hands, with the colored dot facing you - see Figure 2. Hold the upper part of the ampoule so that your thumb is above the colored dot.
  • Press according to the arrow shown in Figure 3.

The ampoules are intended for single use only and should be opened immediately before use. The remaining contents of the unused medicine should be disposed of in accordance with applicable regulations.
Figure 1.

Ampoule with a colored dot marking the break point, gray outline on a white background

Figure 2.

Two hands holding the ampoule with a colored dot, indicating the pressure point

Figure 3.

Two hands pressing the ampoule at the point marked with an arrow, colored dot visible

Using a higher dose of Papaverinum hydrochloricum WZF than recommended

Excessive lowering of blood pressure, blurred or double vision, heart rhythm disorders may occur.
Treatment: the doctor will provide symptomatic treatment.
If a higher dose of the medicine is used than recommended, consult a doctor or pharmacist immediately.

Missing a dose of Papaverinum hydrochloricum WZF

If a dose of the medicine is missed, the next dose should be taken at the scheduled time. Do not take a double dose to make up for the missed dose.
If you have any further doubts about using this medicine, consult your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Flushing of the face, pain and dizziness, discomfort in the abdominal cavity, constipation, diarrhea, malaise, loss of appetite, nausea, vomiting, excessive sweating, drowsiness, hypotension, breathing difficulties, pain at the injection site, eosinophilia, elevated liver test values.
If symptoms such as jaundice or liver pain occur, the medicine should be discontinued and a doctor consulted immediately.

Reporting side effects

If any side effects occur, including any side effects not listed in this leaflet, inform your doctor or pharmacist. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products
Al. Jerozolimskie 181C
02-222 Warsaw
Phone: +48 22 49 21 301
Fax: +48 22 49 21 309
Website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help gather more information on the safety of the medicine.

5. How to store Papaverinum hydrochloricum WZF

Store at a temperature below 25°C. Store the ampoules in the outer packaging to protect them from light. Do not freeze.
The medicine should be stored out of sight and reach of children.
Do not use this medicine after the expiry date stated on the label and carton. The expiry date refers to the last day of the specified month.
The inscription on the packaging after the abbreviation EXP means the expiry date, and after the abbreviation Lot means the batch number.
Medicines should not be disposed of via wastewater or household waste containers. Ask your pharmacist how to dispose of medicines that are no longer needed. This will help protect the environment.

6. Package contents and other information

What Papaverinum hydrochloricum WZF contains

  • The active substance of the medicine is papaverine hydrochloride. Each ml of solution contains 20 mg of papaverine hydrochloride.
  • The other ingredients are: disodium edetate, benzyl alcohol, water for injections.

What Papaverinum hydrochloricum WZF looks like and what the package contains

Papaverinum hydrochloricum WZF is a clear, colorless or slightly yellowish liquid.
10 ampoules of 2 ml each in a cardboard box.

Marketing authorization holder and manufacturer

Zakłady Farmaceutyczne POLPHARMA S.A.
ul. Pelplińska 19, 83-200 Starogard Gdański
phone: +48 22 364 61 01
Date of last update of the leaflet:December 2024

  • Country of registration
  • Active substance
  • Prescription required
    Yes
  • Importer
    Zakłady Farmaceutyczne POLPHARMA S.A.
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Alternative to Papaverinum hidrohloricum Vzf in Ukraine

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Online doctors for Papaverinum hidrohloricum Vzf

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Papaverinum hidrohloricum Vzf – subject to medical assessment and local rules.

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Tarek Agami

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Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

  • Diagnosis and treatment of acute and chronic conditions (high blood pressure, diabetes, respiratory infections, cardiovascular symptoms)
  • Evaluation of symptoms and guidance on further diagnostic testing
  • Preventive check-ups and regular health monitoring
  • Medical support during travel or after relocation
  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

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