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Otrex 600

Otrex 600

Ask a doctor about a prescription for Otrex 600

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Doctor

Yevgen Yakovenko

General surgery11 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Otrex 600

Leaflet attached to the packaging: patient information

OTREX 600; tablets, 600 mg

( Diosmin)

Please read the contents of the leaflet carefully before using the medicine, as it contains

important information for the patient.
This medicine should always be used exactly as described in the patient leaflet, or as directed by
the doctor or pharmacist.

  • This leaflet should be kept, so that it can be read again if necessary.
  • If advice or additional information is needed, the pharmacist should be consulted.
  • If the patient experiences any side effects, including any possible side effects not listed in the leaflet, the doctor or pharmacist should be informed. See section 4.
  • If there is no improvement or the patient feels worse, the doctor should be contacted.

Table of contents of the leaflet

  • 1. What is Otrex 600 and what is it used for
  • 2. Important information before using Otrex 600
  • 3. How to use Otrex 600
  • 4. Possible side effects
  • 5. How to store Otrex 600
  • 6. Package contents and other information

1. What is Otrex 600 and what is it used for

Otrex 600 tablet contains 600 mg of diosmin. The medicine increases the tension of venous vessel walls,
causes normalization of vessel permeability and has a protective effect on vessel walls (increases
the resistance of small blood vessels).
Indications for use of Otrex 600:

  • reducing symptoms associated with venous circulation failure of the lower limbs, such as feelings of heaviness in the legs, leg pain, and discomfort caused by bedsores;
  • symptomatic treatment in case of exacerbation of hemorrhoid symptoms.

2. Important information before using Otrex 600

When not to use Otrex 600

  • if the patient is allergic to diosmin or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions:

  • if the medicine is administered in the exacerbation of hemorrhoid symptoms, it may be necessary to use treatment as in other anorectal diseases. The treatment should be short-term - up to 15 days
  • if the symptoms associated with hemorrhoids persist or worsen despite the use of the medicine, the doctor should be consulted.

Children and adolescents

No data are available.
08583

Otrex 600 and other medicines

The doctor or pharmacist should be informed about all medicines currently being taken by the patient
or recently taken, as well as any medicines that the patient plans to use.
Interactions between Otrex 600 and other medicines are not known.

Pregnancy and breastfeeding

In pregnancy and during breastfeeding, or if pregnancy is suspected or planned, the doctor or pharmacist should be consulted before using this medicine.
The medicine may be used during pregnancy only if necessary.
Due to the lack of data on the penetration of Otrex 600 into breast milk, the use of the medicine during breastfeeding is not recommended.

Driving and using machines

The medicine has no effect on the ability to drive and use machines.

3. How to use Otrex 600

This medicine should always be used exactly as described in the patient leaflet, or as directed by
the doctor or pharmacist. In case of doubts, the doctor or pharmacist should be consulted.
The medicine is administered orally.
Venous circulation failure of the lower limbs:
the usual dose of the medicine is 1 tablet per day, in the morning, on an empty stomach.
Exacerbation of hemorrhoid symptoms:
the usual dose of the medicine is 2 to 3 tablets per day, during meals.

Using a higher dose of Otrex 600 than recommended

In case of taking a higher dose of the medicine than recommended, the doctor or pharmacist should be consulted.
Symptoms of overdose of Otrex 600 are not known.

Missing a dose of Otrex 600

A double dose should not be taken to make up for a missed dose.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Rarely, gastrointestinal disorders (nausea, vomiting) may occur.

Reporting side effects

If any side effects occur, including any side effects not listed in the leaflet, the doctor or pharmacist should be informed. Side effects can be reported directly to: Department of Monitoring of Adverse Reactions to Medicinal Products
Office for Registration of Medicinal Products, Medical Devices and Biocidal Products
Al. Jerozolimskie 181C
02-222 Warsaw
Phone: + 48 22 49 21 301
Fax: + 48 22 49 21 309
e-mail: [email protected]
Reporting side effects will help to gather more information on the safety of the medicine.
08583

5. How to store Otrex 600

The medicine should be stored in a place that is out of sight and reach of children.
The medicine should be stored at a temperature below 25°C.
The medicine should not be used after the expiry date stated on the carton after "expiry date". The expiry date refers to the last day of the stated month.
Medicines should not be disposed of via wastewater or household waste. The pharmacist should be asked how to dispose of medicines that are no longer used. This will help protect the environment.

6. Package contents and other information

What Otrex 600 contains

  • The active substance of the medicine is semi-synthetic diosmin. 1 tablet contains 600 mg of semi-synthetic diosmin.
  • The other ingredients are: corn starch, microcrystalline cellulose, povidone, magnesium stearate.

What Otrex 600 looks like and what the package contains

Otrex 600 tablets are oblong, gray-yellow or light yellow with a dividing groove on both sides.
The tablets are packaged in blisters placed in cardboard cartons. The packages contain 15
and 30 tablets.

Responsible entity and manufacturer

Responsible entity:
Stragen France SAS
30 rue Edouard Nieuport
69008 Lyon
France
Manufacturer:
Phyteo Laboratoire
11, rue de Montbazon
37260 Monts
France
Date of leaflet preparation: February 2020
08583

Alternatives to Otrex 600 in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Otrex 600 in Ukraine

Dosage form: tablets, tablets 600mg
Active substance: diosmin
Manufacturer: Fiteo Laboratuar
Prescription not required
Dosage form: tablets, film-coated tablets, 600 mg
Active substance: diosmin
Manufacturer: Innotera Suzi
Prescription not required
Dosage form: tablets, 500mg tablets in blister
Active substance: diosmin
Manufacturer: KRKA, d.d., Novo mesto
Prescription not required
Dosage form: tablets, 1000 mg tablets in blister
Active substance: diosmin

Alternative to Otrex 600 in Spain

Dosage form: TABLET, Diosmin 450 mg / Hesperidin 50 mg
Active substance: diosmin, diosmin, combinations
Manufacturer: Kern Pharma S.L.
Prescription not required
Dosage form: TABLET, 1000 mg
Active substance: diosmin
Prescription not required
Dosage form: TABLET, 1000 mg
Active substance: diosmin
Prescription not required
Dosage form: CAPSULE, 200 mg
Active substance: hidrosmin
Manufacturer: Faes Farma S.A.
Prescription not required
Dosage form: GEL, 20 mg/g
Active substance: hidrosmin
Manufacturer: Faes Farma S.A.
Prescription not required
Dosage form: CAPSULE, 200 mg
Active substance: hidrosmin
Manufacturer: Faes Farma S.A.
Prescription required

Online doctors for Otrex 600

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Otrex 600 – subject to medical assessment and local rules.

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Antonio Cayatte

General medicine43 years of experience

Dr Antonio Cayatte is a physician in General and Acute Medicine with over 30 years of experience across clinical care, medical research, and education. He offers online consultations for adults with a wide range of symptoms, both acute and chronic.

His clinical background includes:

  • assessment of sudden or unclear symptoms
  • ongoing care for chronic conditions
  • follow-up after hospital discharge
  • interpretation of test results
  • medical support while abroad
Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association.

Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

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Yevgen Yakovenko

General surgery11 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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  • Chronic pain lasting more than 3 months.
  • Migraines and recurring headaches.
  • Neck, back, lower back, and joint pain.
  • Post-traumatic pain following injury or surgery.
  • Nerve-related pain, fibromyalgia, and neuralgia.
In addition to pain management, Dr. Popov helps patients with:
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  • High blood pressure and metabolic conditions such as diabetes.
  • Preventive care and routine health check-ups.

Online consultations last up to 30 minutes and include a detailed symptom review, personalised treatment planning, and medical follow-up when needed.

Dr. Popov’s approach is rooted in evidence-based medicine, combined with individualised care tailored to each patient’s history, lifestyle, and clinical needs.

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  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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  • Emergency care: myocardial infarction, acute left ventricular failure, acute pulmonary heart disease
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She also provides:

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With a patient-focused and evidence-based approach, Dr. Ben Ami supports individuals at all stages of life — offering clear medical guidance, timely interventions, and continuity of care.

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