OTREX 600 mg Tablets

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Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
€86
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Otrex 600

Contents of the leaflet

  1. Leaflet attached to the packaging: patient information
  2. OTREX 600; tablets, 600 mg
    1. Please read the contents of the leaflet carefully before using the medicine, as it contains
    2. Table of contents of the leaflet
  3. What is Otrex 600 and what is it used for
  4. Important information before using Otrex 600
    1. When not to use Otrex 600
    2. Children and adolescents
    3. Otrex 600 and other medicines
    4. Pregnancy and breastfeeding
    5. Driving and using machines
  5. How to use Otrex 600
    1. Using a higher dose of Otrex 600 than recommended
    2. Missing a dose of Otrex 600
  6. Possible side effects
    1. Reporting side effects
  7. How to store Otrex 600
  8. Package contents and other information
    1. What Otrex 600 contains
    2. What Otrex 600 looks like and what the package contains
    3. Responsible entity and manufacturer

Leaflet attached to the packaging: patient information

OTREX 600; tablets, 600 mg

( Diosmin)

Please read the contents of the leaflet carefully before using the medicine, as it contains

important information for the patient.
This medicine should always be used exactly as described in the patient leaflet, or as directed by
the doctor or pharmacist.

  • This leaflet should be kept, so that it can be read again if necessary.
  • If advice or additional information is needed, the pharmacist should be consulted.
  • If the patient experiences any side effects, including any possible side effects not listed in the leaflet, the doctor or pharmacist should be informed. See section 4.
  • If there is no improvement or the patient feels worse, the doctor should be contacted.

Table of contents of the leaflet

  • 1. What is Otrex 600 and what is it used for
  • 2. Important information before using Otrex 600
  • 3. How to use Otrex 600
  • 4. Possible side effects
  • 5. How to store Otrex 600
  • 6. Package contents and other information
Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

1. What is Otrex 600 and what is it used for

Otrex 600 tablet contains 600 mg of diosmin. The medicine increases the tension of venous vessel walls,
causes normalization of vessel permeability and has a protective effect on vessel walls (increases
the resistance of small blood vessels).
Indications for use of Otrex 600:

  • reducing symptoms associated with venous circulation failure of the lower limbs, such as feelings of heaviness in the legs, leg pain, and discomfort caused by bedsores;
  • symptomatic treatment in case of exacerbation of hemorrhoid symptoms.

2. Important information before using Otrex 600

When not to use Otrex 600

  • if the patient is allergic to diosmin or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions:

  • if the medicine is administered in the exacerbation of hemorrhoid symptoms, it may be necessary to use treatment as in other anorectal diseases. The treatment should be short-term - up to 15 days
  • if the symptoms associated with hemorrhoids persist or worsen despite the use of the medicine, the doctor should be consulted.

Children and adolescents

No data are available.
08583

Otrex 600 and other medicines

The doctor or pharmacist should be informed about all medicines currently being taken by the patient
or recently taken, as well as any medicines that the patient plans to use.
Interactions between Otrex 600 and other medicines are not known.

Pregnancy and breastfeeding

In pregnancy and during breastfeeding, or if pregnancy is suspected or planned, the doctor or pharmacist should be consulted before using this medicine.
The medicine may be used during pregnancy only if necessary.
Due to the lack of data on the penetration of Otrex 600 into breast milk, the use of the medicine during breastfeeding is not recommended.

Driving and using machines

The medicine has no effect on the ability to drive and use machines.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

3. How to use Otrex 600

This medicine should always be used exactly as described in the patient leaflet, or as directed by
the doctor or pharmacist. In case of doubts, the doctor or pharmacist should be consulted.
The medicine is administered orally.
Venous circulation failure of the lower limbs:
the usual dose of the medicine is 1 tablet per day, in the morning, on an empty stomach.
Exacerbation of hemorrhoid symptoms:
the usual dose of the medicine is 2 to 3 tablets per day, during meals.

In case of taking a higher dose of the medicine than recommended, the doctor or pharmacist should be consulted.
Symptoms of overdose of Otrex 600 are not known.

Missing a dose of Otrex 600

A double dose should not be taken to make up for a missed dose.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Rarely, gastrointestinal disorders (nausea, vomiting) may occur.

Reporting side effects

If any side effects occur, including any side effects not listed in the leaflet, the doctor or pharmacist should be informed. Side effects can be reported directly to: Department of Monitoring of Adverse Reactions to Medicinal Products
Office for Registration of Medicinal Products, Medical Devices and Biocidal Products
Al. Jerozolimskie 181C
02-222 Warsaw
Phone: + 48 22 49 21 301
Fax: + 48 22 49 21 309
e-mail: [email protected]
Reporting side effects will help to gather more information on the safety of the medicine.
08583

5. How to store Otrex 600

The medicine should be stored in a place that is out of sight and reach of children.
The medicine should be stored at a temperature below 25°C.
The medicine should not be used after the expiry date stated on the carton after "expiry date". The expiry date refers to the last day of the stated month.
Medicines should not be disposed of via wastewater or household waste. The pharmacist should be asked how to dispose of medicines that are no longer used. This will help protect the environment.

6. Package contents and other information

What Otrex 600 contains

  • The active substance of the medicine is semi-synthetic diosmin. 1 tablet contains 600 mg of semi-synthetic diosmin.
  • The other ingredients are: corn starch, microcrystalline cellulose, povidone, magnesium stearate.

What Otrex 600 looks like and what the package contains

Otrex 600 tablets are oblong, gray-yellow or light yellow with a dividing groove on both sides.
The tablets are packaged in blisters placed in cardboard cartons. The packages contain 15
and 30 tablets.

Responsible entity and manufacturer

Responsible entity:
Stragen France SAS
30 rue Edouard Nieuport
69008 Lyon
France
Manufacturer:
Phyteo Laboratoire
11, rue de Montbazon
37260 Monts
France
Date of leaflet preparation: February 2020
08583

  • Otrex 600
  • Country of registration
  • Dosage form
    Tablets, 600 mg
  • ATC code
    C05CA03
  • Active substance
  • Prescription required
    No
  • Manufacturer
  • Importer
    Phyteo Laboratoire
  • Alternatives to Otrex 600
    Dosage form: Tablets, 1000 mg
    Active substance: diosmin
    Manufacturer: Polfarmex S.A.
    Prescription not required
    Dosage form: Tablets, 1000 mg
    Active substance: diosmin
    Prescription not required
    Dosage form: Tablets, 500 mg
    Active substance: diosmin
    Prescription not required

Online doctors for Otrex 600

Discuss questions about Otrex 600, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

Family medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

Family medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(2)

Dmytro Horobets

Family medicineEndocrinology7 years of experience

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

Book a video appointment
€71
Doctor
5.0(19)

Nuno Tavares Lopes

Family medicineGeneral medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

Get Otrex 600 Prescription Online

1

Fill in a 2-min form

Tell us your symptoms, history, and what medicine you're requesting.

2

Pick a doctor or let us assign

Choose a specialist or we'll match you with the next available doctor.

3

Doctor reviews your case

Usually within 30 minutes. They may ask follow-up questions via chat.

4

Collect from any pharmacy

Electronic prescription sent to your email — valid across Spain.

Frequently Asked Questions

Is a prescription required for Otrex 600?

Otrex 600 does not require a prescription in Poland. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in Otrex 600?

The active ingredient in Otrex 600 is diosmin. This information helps identify medicines with the same composition but different brand names.

Who manufactures Otrex 600?

Otrex 600 is manufactured by Phyteo Laboratoire. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of Otrex 600 online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether Otrex 600 is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy Otrex 600 in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy Otrex 600 in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to Otrex 600?

Other medicines with the same active substance (diosmin) include Aflavic Max, Dih Max Comfort, Dih. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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