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Ornispar

Ornispar

Ask a doctor about a prescription for Ornispar

5.0(34)
Doctor

Nuno Tavares Lopes

Family medicine17 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC. He offers online consultations in Portuguese, English, and Spanish — combining global expertise with a patient-centred, evidence-based approach.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.
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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Ornispar

Leaflet attached to the packaging: Patient information

Ornispar, 6 g/10 g, granules for oral solution, in a sachet

Ornithine aspartate

Read the leaflet carefully before taking the medicine, as it contains important information for the patient.

  • Keep this leaflet, so you can read it again if you need to.
  • If you have any doubts, consult your doctor or pharmacist.
  • This medicine has been prescribed to you by a doctor. Do not pass it on to others. The medicine may harm another person, even if their symptoms are the same as yours.
  • If the patient experiences any side effects, including any side effects not listed in this leaflet, they should inform their doctor or pharmacist. See section 4.

Table of contents of the leaflet:

  • 1. What is Ornispar and what is it used for
  • 2. Important information before taking Ornispar
  • 3. How to take Ornispar
  • 4. Possible side effects
  • 5. How to store Ornispar
  • 6. Contents of the packaging and other information

1. WHAT IS ORNISPAR AND WHAT IS IT USED FOR

Ornispar is used to treat latent and overt hepatic encephalopathy occurring in the course of chronic liver diseases, such as chronic hepatitis, liver cirrhosis.

2. IMPORTANT INFORMATION BEFORE TAKING ORNISPAR

When not to take Ornispar

Do not take Ornispar if you have the following disorders:

  • hypersensitivity to L-ornithine L-aspartate or any of the other ingredients of the medicine;
  • severe kidney failure (serum creatinine level above 3 mg/100 ml);
  • disorders of amino acid metabolism involved in the urea cycle, e.g. due to enzymatic defects;
  • fructose intolerance.

Warnings and precautions

Ornispar contains 720 mg of sorbitol in 1 sachet. Sorbitol is a source of fructose. If you have previously been diagnosed with intolerance to some sugars or have been diagnosed with hereditary fructose intolerance, a rare genetic disease in which the patient's body does not break down fructose, you should consult your doctor before taking the medicine.
Ornispar contains isomalt. If you have previously been diagnosed with intolerance to some sugars, you should consult your doctor before taking the medicine.
Ornispar contains 1% propylene glycol.
Before administering the medicine to a child under 4 weeks, consult your doctor or pharmacist, especially if the child is taking other medicines containing propylene glycol or alcohol.
Long-term use of Ornispar may cause tooth decay.
Children:
There is no data on the use of the medicine in children.
Before administering the medicine to infants or children, you must consult your doctor, as there is a possibility of undiagnosed fructose intolerance in the child.

Ornispar and other medicines

Tell your doctor about all the medicines you are taking or have recently taken, as well as any medicines you plan to take.
There are no known interactions between Ornispar and other medicines.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to have a child, consult your doctor before taking this medicine.
Pregnancy:
There are insufficient studies on the safety of using Ornispar during pregnancy, so you should avoid taking the medicine during pregnancy. Ornispar may be taken by pregnant women only if recommended by a doctor.
Breastfeeding:
It is not known whether L-ornithine L-aspartate (the active substance of Ornispar) passes into breast milk. You should avoid taking the medicine during breastfeeding.
Ornispar may be taken by breastfeeding women only if recommended by a doctor.

Driving and operating machinery

The ability to drive vehicles and operate machinery may be impaired due to the disease being treated with Ornispar.

Ornispar contains sorbitol, isomalt, and propylene glycol.

See the "Warnings and precautions" section.

3. HOW TO TAKE ORNISPAR

Always take this medicine exactly as your doctor has told you. If you are not sure, consult your doctor or pharmacist.
The usual dose is 1 sachet 3 times a day.
The contents of the sachet should be dissolved in a glass of water. Take during or after a meal.
If you feel that the effect of the medicine is too strong or too weak, consult your doctor or pharmacist.

Method of administration

Oral administration.

Overdose of Ornispar

No symptoms of overdose have been observed with Ornispar so far.
In case of overdose, symptomatic treatment is used.

Missed dose of Ornispar

Take the next dose at the right time, according to the dosing instructions. Do not take a double dose to make up for a missed dose. If you have any doubts about taking the medicine, consult your doctor or pharmacist.

4. POSSIBLE SIDE EFFECTS

Like all medicines, Ornispar can cause side effects, although not everybody gets them.

Uncommon side effects (less than 1 in 100 people):

nausea; vomiting; stomach pain; bloating; diarrhea.

Rare side effects (less than 1 in 10,000 people):

limb pain.
The listed side effects are usually temporary and do not require discontinuation of the medicine.

Reporting side effects

If you experience any side effects, including any side effects not listed in this leaflet, tell your doctor, pharmacist, or nurse. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products,
Aleje Jerozolimskie 181C
02-222 Warsaw
tel.: +48 22 49 21 301,
fax: +48 22 49 21 309
website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help to gather more information on the safety of the medicine.

5. HOW TO STORE ORNISPAR

Keep out of sight and reach of children.
There are no special precautions for storing the medicine.
Do not use the medicine after the expiry date stated on the carton. The expiry date refers to the last day of the month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines that are no longer needed. This will help protect the environment.

6. CONTENTS OF THE PACKAGING AND OTHER INFORMATION

What Ornispar contains

The active substance of the medicine is L-ornithine L-aspartate.
1 sachet (10 g granules) contains 6 g of L-ornithine L-aspartate.
Excipients:
citric acid, sorbitol, ananas flavor (flavor enhancers, corn waxy maltodextrin, modified corn waxy starch), sucralose (E 955),
silica colloidal anhydrous, peppermint flavor (natural menthol, peppermint oil Mentha piperita L., spearmint oil Mentha spicata L.,
maltodextrin, arabic gum, propylene glycol), sodium riboflavin phosphate (E 101), isomalt.

What Ornispar looks like and what the pack contains

Ornispar is white or slightly yellow granules.
Packaging: 10, 20, 30, 50, or 100 sachets of 4-layer laminate (paper/PE/aluminum/Surlyn) or sachets of 5-layer laminate (paper/polyurethane solvent-based two-component/aluminum/polyurethane solvent-based two-component/LDPE) in a cardboard box.
Not all pack sizes may be marketed.

Marketing authorization holder:

Solinea Sp. z o.o.
Elizówka, ul. Szafranowa 6
21-003 Ciecierzyn
Poland
tel.: +48 81 463 48 82
[Solinea logo ]

Manufacturer:

Mako Pharma Sp. z o.o.
Kolejowa 231A
05-092 Dziekanów Polski
Medicofarma S.A.
ul. Tarnobrzeska 13
26-613 Radom

Date of approval of the leaflet: 04.2024

  • Country of registration
  • Prescription required
    Yes
  • Importer
    Mako Pharma Sp. z o.o. Medicofarma S.A.
  • Alternatives to Ornispar
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    Active substance: ornithine oxoglurate
    Prescription required
    Dosage form: Granulate, 3 g/5 g
    Active substance: ornithine oxoglurate
    Prescription required
    Dosage form: Granulate, 3 g/5 g
    Active substance: ornithine oxoglurate
    Prescription required

Alternatives to Ornispar in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Ornispar in Spain

Dosage form: CAPSULE, 300 mg
Prescription not required
Dosage form: CAPSULE, 100 mg Dry extract of milk thistle (equivalent to 80 mg of silymarin)
Active substance: silymarin
Prescription required
Dosage form: INJECTABLE PERFUSION, 350 mg sodium silibinate
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Dosage form: CAPSULE, 150 mg silymarin
Active substance: silymarin
Prescription required
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Prescription not required
Dosage form: CAPSULE, 390 mg
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Alternative to Ornispar in Ukraine

Dosage form: fruits, 50 g, or 100 g, or 200 g
Manufacturer: PRAT "FITOFARM
Prescription not required
Dosage form: fruits, 50 g, 100 g or 200 g
Prescription not required
Dosage form: lyophilizate, 1 vial (bottle) contains lecithin standard - 320 mg; anthral - 4.2 mg
Manufacturer: TOV "BIOLIK FARMA
Prescription required
Dosage form: capsules, 10 capsules in a blister
Prescription not required
Dosage form: solution, 50mg/ml in 5ml ampoule
Manufacturer: AT "Farmak
Prescription required
Dosage form: capsules, 10 capsules in a blister
Manufacturer: Nabros Farma Pvt. Ltd.
Prescription not required

Online doctors for Ornispar

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Ornispar – subject to medical assessment and local rules.

5.0(34)
Doctor

Nuno Tavares Lopes

Family medicine17 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC. He offers online consultations in Portuguese, English, and Spanish — combining global expertise with a patient-centred, evidence-based approach.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.
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  • Preventive care: health check-ups, lifestyle advice, and follow-up for existing conditions
  • Work-related health questions, sick leave documentation, and medical guidance for returning to work
Dr. Meneses graduated from the University of Beira Interior and has years of experience working with diverse patient populations. He is fluent in Portuguese, English, Spanish, and French.

His approach is friendly, clear, and focused on delivering practical medical advice tailored to each patient’s needs.

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Dr. Alhasan’s approach is based on thorough assessment, clear communication, and personalised care – helping patients understand their health and make informed decisions about their treatment.
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  • Ongoing care for chronic or complex health conditions.
  • Guidance for parents and follow-up after medical treatment.

Dr Akhvlediani combines professional care with a warm, attentive approach – helping children stay healthy and supporting parents at every stage of their child’s growth.

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Dr Travkina follows evidence-based guidelines and ensures patients receive clear explanations and follow-up recommendations. Whether you need help with ENT symptoms, clarification of test results, or guidance on next steps – she offers expert medical advice in a convenient online format.
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Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

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She offers care for people undergoing GLP-1 therapy (Ozempic, Mounjaro, and others) for weight management. Her support follows Spanish clinical guidelines, from treatment planning and side effect counselling to regular follow-ups and coordination with private or public healthcare providers.

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Dr. Fursenko helps patients manage symptoms early, avoid complications, and receive timely treatment. Online ENT consultations are a convenient way to access care for both urgent and recurring conditions — from anywhere.

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