Background pattern
Ismigen

Ismigen

Ask a doctor about a prescription for Ismigen

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Ismigen

B. PATIENT LEAFLET

Leaflet enclosed with the packaging: information for the patient

ISMIGEN

Sublingual tablets

It is essential to carefully read the contents of the leaflet before taking the medicine, as it contains important information for the patient.

  • This leaflet should be kept, so it can be re-read if necessary.
  • In case of any doubts, the patient should consult a doctor or pharmacist.
  • This medicine has been prescribed to a specific person. It should not be given to others. The medicine may harm another person, even if their disease symptoms are the same.
  • If the patient experiences any adverse reactions, including any adverse reactions not listed in this leaflet, they should inform their doctor or pharmacist.

Table of contents of the leaflet:

  • 1. What is ISMIGEN and what is it used for
  • 2. Important information before taking ISMIGEN
  • 3. How to take ISMIGEN
  • 4. Possible side effects
  • 5. How to store ISMIGEN
  • 6. Package contents and other information

1. What is ISMIGEN and what is it used for

ISMIGEN is indicated for use in the following age groups:
ADULTS
Prevention of recurrent respiratory tract infections (RTI) in adults.
CHILDREN
Prevention of recurrent respiratory tract infections (RTI) in children from 3 years of age.

2. Important information before taking ISMIGEN

When not to take ISMIGEN:

If the patient is allergic to the active substances or any of the other ingredients of this medicine listed in section 6.

Warnings and precautions

Before starting to take ISMIGEN, the patient should discuss it with their doctor or pharmacist.
It is not recommended to use ISMIGEN to prevent pneumonia, as there are no clinical trial data confirming such an effect.

ISMIGEN and other medicines

No interactions with other medicines have been found.
The patient should inform their doctor about all medicines they are currently taking or have recently taken, as well as any medicines they plan to take.

Pregnancy and breastfeeding

If the patient is pregnant or breastfeeding, thinks they may be pregnant, or plans to have a child, they should consult their doctor or pharmacist before using this medicine.

Driving and using machines

No studies have been conducted on the effect of the medicine on the ability to drive and use machines.

3. How to take ISMIGEN

This medicine should always be taken according to the doctor's recommendations. In case of doubts, the patient should consult their doctor or pharmacist.
The recommended dose is:

Adults

One tablet per day before meals, to be dissolved under the tongue. To be taken for ten consecutive days per month, for a period of 3 months.

Use in children and adolescents (from 3 years of age and above)

One tablet per day before meals, to be dissolved under the tongue. To be taken for ten consecutive days per month, for a period of 3 months.
Method of administration
Sublingually: to be dissolved under the tongue.
The score line on the tablet is only to facilitate breaking the tablet to make it easier to swallow.

Taking a higher dose of ISMIGEN than recommended

In case of taking a higher dose of ISMIGEN than recommended, the patient should immediately contact their doctor or pharmacist.

Missing a dose of ISMIGEN

A double dose should not be taken to make up for a missed dose.

Stopping the use of ISMIGEN

In case of any further doubts related to the use of this medicine, the patient should consult their doctor or pharmacist.

4. Possible side effects

Like all medicines, ISMIGEN can cause side effects, although not everybody gets them.
Side effects reported after the vaccine was placed on the market (frequency not known): sore throat, allergic-type hypersensitivity reactions including urticaria, rash, itching, and swelling, fever and headache, vomiting and abdominal pain.

Reporting side effects

If any side effects occur, including any side effects not listed in this leaflet, the patient should inform their doctor or pharmacist. Side effects can be reported directly to:
Department for Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products
Al. Jerozolimskie 181C
02-222 Warsaw
Phone: +48 22 49 21 301
Fax: +48 22 49 21 309
Website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help to gather more information on the safety of the medicine.

5. How to store ISMIGEN

The medicine should be stored out of sight and reach of children.
There are no special precautions for storage.
The expiry date stated on the packaging applies only to the intact product.
The medicine should not be used after the expiry date stated on the carton.
Medicines should not be disposed of via wastewater or household waste. The patient should ask their pharmacist how to dispose of medicines that are no longer needed. This will help protect the environment.

6. Package contents and other information

What ISMIGEN contains

Each tablet contains 7 mg of bacterial lysate:
Staphylococcus aureus
6 billion
Streptococcus pyogenes
6 billion
Streptococcus (viridans) oralis
6 billion
Klebsiella pneumoniae
6 billion
Klebsiella ozaenae
6 billion
Haemophilus influenzae
6 billion
Neisseria catarrhalis
6 billion
Streptococcus pneumoniae
6 billion
(including type TY1 - 1 billion, type TY2 - 1 billion, type TY3 - 1 billion, type TY5 - 1 billion, type TY8 - 1 billion, type TY47 - 1 billion)
and 43 mg of glycine.
Excipients:
microcrystalline cellulose, calcium hydrogen phosphate dihydrate, colloidal anhydrous silica, magnesium stearate, ammonium glycyrrhizinate, powdered peppermint extract.

What ISMIGEN looks like and what the package contains

Available packages: 3 blisters of 10 sublingual tablets, in a cardboard box.

Marketing authorization holder and manufacturer

Marketing authorization holder:

LALLEMAND Pharma Europe
Bredstrupvej 33
8500 Grenaa
Denmark

Manufacturer:

Bruschettini S.r.l.
Via Isonzo 6
16147 Genoa
Italy

Date of last update of the leaflet:

Alternatives to Ismigen in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Ismigen in Ukraina

Dosage form: lyophilized, 1 vial of lyophilized powder (one dose) and 1 ampoule of solvent 0.5 ml
Prescription required
Dosage form: solution, 1 ml in ampoule
Dosage form: spray, 300 FTU/ml, 9 ml in a bottle
Manufacturer: INMUNOTEK, S.L.
Prescription required
Dosage form: spray, 300 FTU/ml; 9 ml in a bottle
Manufacturer: INMUNOTEK, S.L.
Prescription required
Dosage form: drops, 18 ml in a bottle
Manufacturer: BRUSCETTINI S.R.L.
Prescription required

Online doctors for Ismigen

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Ismigen – subject to medical assessment and local rules.

0.0(2)
Doctor

Marianna Neshta

Endocrinology24 years of experience

Marianna Neshta is a medical doctor specialising in endocrinology and ultrasound diagnostics. She provides online consultations for adults, focusing on the diagnosis, treatment, and long-term management of endocrine disorders. Her approach includes personalised care plans, analysis of lab results and ultrasound scans, and evidence-based treatment.

Key areas of expertise:

  • Type 1 and Type 2 diabetes – diagnosis, therapy adjustment, CGM interpretation, and prevention of chronic complications
  • Obesity – treatment using both medication and lifestyle strategies, including modern GLP-1 medications and tailored follow-up plans
  • Thyroid disorders – ultrasound assessment, treatment planning, and management during pregnancy
  • Male hypogonadism – age-related or hormonal, including diagnostics and therapy
  • Metabolic syndrome, prediabetes, lipid disorders – risk assessment, lifestyle recommendations, and medical treatment
  • Calcium metabolism disorders – diagnosis and management of osteoporosis, hyperparathyroidism, and hypoparathyroidism
Dr Neshta applies current clinical guidelines and diagnostic tools, offering medical support adapted to each patient’s individual needs — all in an accessible online format.
CameraBook a video appointment
€45
December 2017:00
December 2017:45
December 2717:00
December 2717:45
January 317:00
More times
0.0(1)
Doctor

Khrystyna Habrykevych

Gastroenterology6 years of experience

Dr Khrystyna Habrykevych is a gastroenterologist providing online consultations for adults with digestive and abdominal health concerns. She helps patients understand the causes of their symptoms, interpret test results, and choose appropriate next steps – whether it’s further investigation, treatment, or lifestyle adjustments.

Common reasons for consultation include:

  • abdominal pain, cramps, discomfort, painful bowel movements
  • heartburn, acid reflux, burping, bitter taste in the mouth
  • bloating, excessive gas, nausea or vomiting
  • diarrhoea, constipation, difficulty passing stool
  • unexplained changes in weight or appetite
  • concern about gut health or long-term digestive issues
  • changes in lab results, questions about test interpretation
  • digestive system cancer screening and prevention
  • general digestive check-ups and health assessments
Dr Habrykevych follows evidence-based medical standards and adapts each consultation to the patient’s individual situation. The online format allows for timely medical support without the need for an in-person visit.
CameraBook a video appointment
€60
December 2106:00
December 2806:00
January 406:00
January 1106:00
More times
0.0(0)
Doctor

Nataliia Lifantieva

Cardiology21 years of experience

Dr. Nataliia Lifantieva is a cardiologist and cardiac electrophysiologist with extensive experience in the diagnosis and treatment of arrhythmias. She offers online consultations for patients with chronic cardiovascular conditions, including medication management and post-operative follow-up.

Main areas of expertise:

  • Diagnosis and treatment of arrhythmias: extrasystole, atrial fibrillation and flutter, supraventricular and ventricular tachycardia
  • Conduction disorders: AV blocks, sinoatrial block, bradyarrhythmias
  • ECG and Holter monitor interpretation, including data from smartwatches
  • Evaluation for interventional treatment: stenting, bypass surgery, valve replacement
  • Anticoagulant management (e.g., warfarin, DOACs) based on kidney function and clinical context
  • Perioperative advice on anticoagulant/antiplatelet therapy before dental procedures
CameraBook a video appointment
€85
December 2108:00
December 2108:55
December 2109:50
December 2110:45
December 2111:40
More times
5.0(15)
Doctor

Giorgi Eremeishvili

Urology21 years of experience

Giorgi Eremeishvili is a top-category urologist, a Candidate of Medical Sciences, and a licensed physician in Spain. He provides expert assistance in the diagnosis and treatment of a wide range of urological conditions in both men and women, employing a comprehensive approach and evidence-based principles.

Key areas of expertise:

  • Erectile dysfunction, decreased libido, premature ejaculation.
  • Male infertility: comprehensive diagnosis and modern treatment methods.
  • Prostate gland diseases: acute and chronic prostatitis, prostatic adenoma (benign prostatic hyperplasia), prostate cancer.
  • Inflammatory diseases of the genitourinary system: acute and chronic cystitis, pyelonephritis, epididymitis, orchitis, urethritis.
  • Sexually transmitted infections (STIs): chlamydia, ureaplasmosis, mycoplasmosis, gardnerellosis, candidiasis, herpetic infections, HPV, CMV, trichomoniasis, and others.
  • Urination disorders: urinary retention, frequent urination, urinary incontinence, overactive bladder, neurogenic bladder.
  • Neoplasms: cysts, tumors of the kidneys, bladder, testicles, prostate gland (including prostate cancer).
  • Surgical interventions: determining indications and selecting optimal minimally invasive methods.

Dr. Eremeishvili applies an integrated approach to each case. This includes thorough preoperative preparation, postoperative observation, and regular dynamic follow-up during the treatment process to achieve the best possible outcomes. All diagnostic and therapeutic recommendations are based on current evidence-based medicine and comply with the recommendations of the European Association of Urology, guaranteeing high-quality and effective care.

If you are seeking qualified assistance in diagnosing or treating urological conditions, book an online consultation with Dr. Giorgi Eremeishvili. Get expert support, accurate diagnosis, and a personalized treatment plan from the comfort of your home.

CameraBook a video appointment
€60
December 2112:00
December 2112:40
December 2212:00
December 2212:40
December 2312:00
More times
0.0(1)
Doctor

Sergei Nalkin

Neurology11 years of experience

Dr. Sergei Nalkin, PhD, is a neurologist, specialising in sports medicine and rehabilitation. He provides expert care for patients with neurological, musculoskeletal, and post-traumatic conditions, focusing on functional recovery and long-term symptom relief.

Dr. Nalkin offers consultations and treatment for:

  • Neurological disorders including migraines, tension headaches, and peripheral neuropathies.
  • Rehabilitation after stroke, brain injury, and spinal cord trauma.
  • Chronic pain syndromes and musculoskeletal dysfunctions.
  • Sports-related injuries: prevention, treatment, and recovery planning.
  • Coordination and movement disorders affecting mobility and balance.
  • Custom rehabilitation programmes for neurological and orthopedic conditions.

With a personalised, evidence-based approach, Dr. Nalkin helps patients restore physical function, reduce pain, and improve quality of life through targeted therapy and long-term support.

CameraBook a video appointment
€55
December 2113:00
December 2113:40
December 2114:20
December 2115:00
December 2813:00
More times
5.0(25)
Doctor

Anna Biriukova

General medicine5 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
CameraBook a video appointment
€60
December 2113:00
December 2113:50
December 2114:40
December 2213:00
December 2213:50
More times
0.0(0)
Doctor

Liudmyla Boichuk

Family medicine10 years of experience

Dr Liudmyla Boichuk is a family medicine doctor providing diagnosis and treatment for a wide range of acute and chronic conditions in adults and children. She works with respiratory, cardiovascular and digestive system disorders and has extensive experience caring for patients with multiple coexisting conditions, where coordinated, whole-person management is essential.

She treats adults with respiratory illnesses such as pneumonia, COPD and bronchial asthma, as well as cardiovascular conditions including hypertension and ischaemic heart disease. Her practice also covers gastrointestinal complaints and chronic comorbidities that require careful, structured medical supervision.

Dr Boichuk provides care for children from birth, including acute respiratory viral infections, infectious diseases, pneumonia, bronchitis, bronchial obstruction syndromes and allergic reactions. She offers clear, evidence-based guidance to parents and ensures safe follow-up throughout the child’s recovery.

Her work also includes developing personalised immunisation plans and supporting families with long-term preventive care.

Known for her structured clinical approach and clear communication, Dr Liudmyla Boichuk offers patients of all ages comprehensive, reliable and evidence-based medical care.

CameraBook a video appointment
€55
December 2113:30
December 2813:30
January 413:30
January 1113:30
More times
5.0(21)
Doctor

Ekaterina Agapova

Neurology8 years of experience

Dr. Ekaterina Agapova is a neurologist specialising in the diagnosis and treatment of neurological conditions and chronic pain. She provides online consultations for adults, combining evidence-based medicine with a personalised approach.

She offers expert care for:

  • Headaches and migraines, including tension-type and cluster headaches.
  • Neck and back pain, both acute and chronic.
  • Chronic pain syndromes – fibromyalgia, neuropathic pain, post-traumatic pain.
  • Mononeuropathies – carpal tunnel syndrome, trigeminal neuralgia, facial nerve palsy.
  • Polyneuropathies – diabetic, toxic, and other types.
  • Multiple sclerosis – diagnosis, monitoring, long-term support.
  • Dizziness and coordination disorders.
  • Sleep disturbances – insomnia, daytime sleepiness, fragmented sleep.
  • Anxiety, depression, and stress-related conditions.

Dr. Agapova helps patients manage complex neurological symptoms like pain, numbness, weakness, poor sleep, and emotional distress. Her consultations focus on accurate diagnosis, clear explanation of findings, and tailored treatment plans.

If you’re struggling with chronic pain, migraines, nerve disorders, or sleep problems, Dr. Agapova offers professional guidance to restore your well-being.

CameraBook a video appointment
€49
December 2206:00
December 2206:45
December 2207:30
December 2208:15
December 2209:00
More times
0.0(0)
Doctor

Marta Reguero Capilla

Allergology7 years of experience

Dr Marta Reguero Capilla is an allergist and immunologist who works with both adults and children. She specialises in the diagnosis, treatment, and ongoing management of allergic and immune-related conditions through online consultations.

In her practice, Dr Reguero Capilla helps patients understand the causes of their symptoms, review test results, and choose appropriate treatment or monitoring strategies. Her consultations are suitable both for first-time assessments and for follow-up care over time.

Patients commonly consult Dr Marta Reguero Capilla for:

  • allergic rhinitis, seasonal allergies, and perennial allergy symptoms;
  • allergic conditions in adults and children;
  • bronchial asthma and allergy-related respiratory symptoms;
  • urticaria (acute and chronic) and angioedema;
  • food allergies and reactions to foods, additives, or medications;
  • atopic dermatitis, allergic rashes, and persistent itching;
  • unexplained or recurrent allergic reactions;
  • interpretation of laboratory tests, allergy testing, and immunology results;
  • immune system concerns, frequent infections, and reduced immune response;
  • ongoing medical follow-up and treatment adjustment.
Dr Reguero Capilla works in a structured and attentive manner, explaining medical decisions clearly and helping patients make informed choices about their own health or their child’s care.

When clinically appropriate, she may provide recommendations for further tests or referrals that patients can use within Spanish medical networks, including Sanitas and DKV, in accordance with the terms and conditions of those services.

CameraBook a video appointment
€60
December 2208:30
December 2208:55
December 2209:20
December 2209:45
December 2210:10
More times
0.0(0)
Doctor

Nikita Savin

Pediatrics4 years of experience

Dr. Nikita Savin is a paediatrician providing online consultations for children of all ages. He offers comprehensive medical care with a focus on preventive health, proper development, and long-term management of chronic and complex conditions.

His areas of expertise include:

  • Preventive care and vaccination planning, including catch-up schedules for children.
  • Assessment of psychomotor, emotional, and physical development.
  • Diagnosis, treatment planning, and clinical monitoring for paediatric conditions.
  • Nutritional guidance for infants, including the choice of adapted milk formulas tailored to medical needs.
  • Early identification of rare and orphan diseases.
  • Ongoing care for children with chronic or complex health conditions.
By combining paediatrics with a personalised approach, Dr. Savin ensures professional support that addresses both the physical health and overall well-being of children, while guiding parents at every stage of their child’s growth.
CameraBook a video appointment
€79
December 2209:00
December 2210:00
December 2211:00
December 2508:00
December 2509:00
More times

Get updates and exclusive offers

Be the first to know about new services, marketplace updates, and subscriber-only promos.

Follow us on social media
FacebookInstagram
Logo
Oladoctor
Find a doctor
Doctors by specialty
Services
Choose language
© 2025 Oladoctor. All rights reserved.
VisaMastercardStripe