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Ismigen

Ismigen

Ask a doctor about a prescription for Ismigen

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Doctor

Tarek Agami

General medicine10 years of experience

Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

  • Diagnosis and treatment of acute and chronic conditions (high blood pressure, diabetes, respiratory infections, cardiovascular symptoms)
  • Evaluation of symptoms and guidance on further diagnostic testing
  • Preventive check-ups and regular health monitoring
  • Medical support during travel or after relocation
  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Ismigen

B. PATIENT LEAFLET

Leaflet enclosed with the packaging: information for the patient

ISMIGEN

Sublingual tablets

It is essential to carefully read the contents of the leaflet before taking the medicine, as it contains important information for the patient.

  • This leaflet should be kept, so it can be re-read if necessary.
  • In case of any doubts, the patient should consult a doctor or pharmacist.
  • This medicine has been prescribed to a specific person. It should not be given to others. The medicine may harm another person, even if their disease symptoms are the same.
  • If the patient experiences any adverse reactions, including any adverse reactions not listed in this leaflet, they should inform their doctor or pharmacist.

Table of contents of the leaflet:

  • 1. What is ISMIGEN and what is it used for
  • 2. Important information before taking ISMIGEN
  • 3. How to take ISMIGEN
  • 4. Possible side effects
  • 5. How to store ISMIGEN
  • 6. Package contents and other information

1. What is ISMIGEN and what is it used for

ISMIGEN is indicated for use in the following age groups:
ADULTS
Prevention of recurrent respiratory tract infections (RTI) in adults.
CHILDREN
Prevention of recurrent respiratory tract infections (RTI) in children from 3 years of age.

2. Important information before taking ISMIGEN

When not to take ISMIGEN:

If the patient is allergic to the active substances or any of the other ingredients of this medicine listed in section 6.

Warnings and precautions

Before starting to take ISMIGEN, the patient should discuss it with their doctor or pharmacist.
It is not recommended to use ISMIGEN to prevent pneumonia, as there are no clinical trial data confirming such an effect.

ISMIGEN and other medicines

No interactions with other medicines have been found.
The patient should inform their doctor about all medicines they are currently taking or have recently taken, as well as any medicines they plan to take.

Pregnancy and breastfeeding

If the patient is pregnant or breastfeeding, thinks they may be pregnant, or plans to have a child, they should consult their doctor or pharmacist before using this medicine.

Driving and using machines

No studies have been conducted on the effect of the medicine on the ability to drive and use machines.

3. How to take ISMIGEN

This medicine should always be taken according to the doctor's recommendations. In case of doubts, the patient should consult their doctor or pharmacist.
The recommended dose is:

Adults

One tablet per day before meals, to be dissolved under the tongue. To be taken for ten consecutive days per month, for a period of 3 months.

Use in children and adolescents (from 3 years of age and above)

One tablet per day before meals, to be dissolved under the tongue. To be taken for ten consecutive days per month, for a period of 3 months.
Method of administration
Sublingually: to be dissolved under the tongue.
The score line on the tablet is only to facilitate breaking the tablet to make it easier to swallow.

Taking a higher dose of ISMIGEN than recommended

In case of taking a higher dose of ISMIGEN than recommended, the patient should immediately contact their doctor or pharmacist.

Missing a dose of ISMIGEN

A double dose should not be taken to make up for a missed dose.

Stopping the use of ISMIGEN

In case of any further doubts related to the use of this medicine, the patient should consult their doctor or pharmacist.

4. Possible side effects

Like all medicines, ISMIGEN can cause side effects, although not everybody gets them.
Side effects reported after the vaccine was placed on the market (frequency not known): sore throat, allergic-type hypersensitivity reactions including urticaria, rash, itching, and swelling, fever and headache, vomiting and abdominal pain.

Reporting side effects

If any side effects occur, including any side effects not listed in this leaflet, the patient should inform their doctor or pharmacist. Side effects can be reported directly to:
Department for Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products
Al. Jerozolimskie 181C
02-222 Warsaw
Phone: +48 22 49 21 301
Fax: +48 22 49 21 309
Website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help to gather more information on the safety of the medicine.

5. How to store ISMIGEN

The medicine should be stored out of sight and reach of children.
There are no special precautions for storage.
The expiry date stated on the packaging applies only to the intact product.
The medicine should not be used after the expiry date stated on the carton.
Medicines should not be disposed of via wastewater or household waste. The patient should ask their pharmacist how to dispose of medicines that are no longer needed. This will help protect the environment.

6. Package contents and other information

What ISMIGEN contains

Each tablet contains 7 mg of bacterial lysate:
Staphylococcus aureus
6 billion
Streptococcus pyogenes
6 billion
Streptococcus (viridans) oralis
6 billion
Klebsiella pneumoniae
6 billion
Klebsiella ozaenae
6 billion
Haemophilus influenzae
6 billion
Neisseria catarrhalis
6 billion
Streptococcus pneumoniae
6 billion
(including type TY1 - 1 billion, type TY2 - 1 billion, type TY3 - 1 billion, type TY5 - 1 billion, type TY8 - 1 billion, type TY47 - 1 billion)
and 43 mg of glycine.
Excipients:
microcrystalline cellulose, calcium hydrogen phosphate dihydrate, colloidal anhydrous silica, magnesium stearate, ammonium glycyrrhizinate, powdered peppermint extract.

What ISMIGEN looks like and what the package contains

Available packages: 3 blisters of 10 sublingual tablets, in a cardboard box.

Marketing authorization holder and manufacturer

Marketing authorization holder:

LALLEMAND Pharma Europe
Bredstrupvej 33
8500 Grenaa
Denmark

Manufacturer:

Bruschettini S.r.l.
Via Isonzo 6
16147 Genoa
Italy

Date of last update of the leaflet:

Alternatives to Ismigen in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Ismigen in Ukraine

Dosage form: lyophilized, 1 vial of lyophilized powder (one dose) and 1 ampoule of solvent 0.5 ml
Prescription required
Dosage form: solution, 1 ml in ampoule
Dosage form: spray, 300 FTU/ml, 9 ml in a bottle
Manufacturer: INMUNOTEK, S.L.
Prescription required
Dosage form: spray, 300 FTU/ml; 9 ml in a bottle
Manufacturer: INMUNOTEK, S.L.
Prescription required
Dosage form: drops, 18 ml in a bottle
Manufacturer: BRUSCETTINI S.R.L.
Prescription required

Online doctors for Ismigen

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Ismigen – subject to medical assessment and local rules.

5.0(7)
Doctor

Tarek Agami

General medicine10 years of experience

Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

  • Diagnosis and treatment of acute and chronic conditions (high blood pressure, diabetes, respiratory infections, cardiovascular symptoms)
  • Evaluation of symptoms and guidance on further diagnostic testing
  • Preventive check-ups and regular health monitoring
  • Medical support during travel or after relocation
  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

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Dr. Alhasan’s approach is based on thorough assessment, clear communication, and personalised care – helping patients understand their health and make informed decisions about their treatment.
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