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Iruxol Mono

Iruxol Mono

Ask a doctor about a prescription for Iruxol Mono

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Doctor

Svetlana Kolomeeva

Cardiology17 years of experience

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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Doctor

Yevgen Yakovenko

General surgery11 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Iruxol Mono

Package Leaflet: Information for the User

IROXOL MONO 1.2 j/g, ointment

Collagenase

Read the package leaflet carefully before using the medicine, as it contains important information for the patient.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist, or nurse.
  • This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, including those not listed in this leaflet, please inform your doctor, pharmacist, or nurse. See section 4.

Table of Contents of the Leaflet

  • 1. What is IRUXOL MONO and what is it used for
  • 2. Important information before using IRUXOL MONO
  • 3. How to use IRUXOL MONO
  • 4. Possible side effects
  • 5. How to store IRUXOL MONO
  • 6. Contents of the pack and other information

1. What is IRUXOL MONO and what is it used for

IRUXOL MONO contains the active substance collagenase - clostridiopeptidase A and accompanying proteases. Collagenase is a proteolytic enzyme that causes the breakdown of collagen fibers.
The collagenase and other proteases in the medicine remove all protein elements from the wound, resulting in the acceleration of the wound cleaning process.
Indications
Enzymatic cleaning of wounds (ulcers and burns of limited surface area) from necrotic tissues.

2. Important information before using IRUXOL MONO

When not to use IRUXOL MONO

  • on extensive burns.

Warnings and precautions

In the case of burns, the ointment should be applied to no more than 10% of the body surface area after prior consultation with a burn treatment specialist.
Contact with the eyes and mucous membranes should be avoided.
In patients with diabetes, dry gangrene should be moistened with caution to avoid the development of wet gangrene.
If the reduction of necrotic tissue does not occur within 14 days, you should contact your doctor to change the treatment method.

IRUXOL MONO and other medicines

Tell your doctor or pharmacist about all medicines you are taking or have recently taken, as well as any medicines you plan to take.
Do not use IRUXOL MONO at the same time as disinfecting medicines, detergents containing heavy metals, and soap, as they weaken the activity of collagenase.
Do not use other local medicines, especially antibiotics such as tyrothricin, gramicidin, and tetracycline, during treatment with IRUXOL MONO, as they may affect the activity of collagenase.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to have a child, consult your doctor or pharmacist before using this medicine.
IRUXOL MONO may be used in the first trimester of pregnancy only if, in the doctor's opinion, it is absolutely necessary.

Driving and using machines

While using IRUXOL MONO, you can drive and operate machinery.

3. How to use IRUXOL MONO

This medicine should always be used according to the doctor's recommendations. If you are unsure, consult your doctor or pharmacist.
The medicine is intended for local use on the skin.
To achieve the best wound healing results with IRUXOL MONO, ensure adequate moisture in the wound area.
Dry wounds should be moistened with a physiological saline solution (0.9% sodium chloride solution) or another well-tolerated solution.
Dry and hard scab-covered wounds should first be softened using a moistening dressing.
If the wounds are infected, the doctor will apply an appropriate antibiotic (such as chloramphenicol, neomycin, framycetin, bacitracin, gentamicin, polymyxin B, macrolides - e.g., erythromycin, clindamycin - mupirocin, sulfadiazine, fusidic acid sodium salt, or clotrimazole).
Apply a 2 mm layer of the medicine to the dressing or directly to the properly prepared (see above) moistened wound surface once a day. Ensure access to the wound surface is maintained.
Do not apply an excessive amount of medicine to the wound, as it does not accelerate the wound healing process.
To avoid irritation, the wound edges and healthy skin should be protected from the action of the medicine.
The dressing should be changed once a day.
In the case of circulatory disorders, ulcers of ischemic origin in diabetes, or neurologic origin, the doctor will apply appropriate causal treatment. It has not been shown that IRUXOL MONO is effective in the treatment of ulcers in the course of venous disease of the lower limbs.
If you feel that the action is too strong or too weak, consult your doctor.

Overdose of IRUXOL MONO

In case of ingestion, remove the medicine from the gastrointestinal tract (e.g., through vomiting, stomach lavage) .

Missed application of IRUXOL MONO

Do not apply a double dose to make up for a missed application of the ointment.
If you have missed several doses, inform your attending doctor and follow their recommendations.

Discontinuation of IRUXOL MONO

Treatment with IRUXOL MONO may only be discontinued on the doctor's instructions.

4. Possible side effects

Like all medicines, IRUXOL MONO can cause side effects, although not everybody gets them.
IRUXOL MONO is usually well tolerated.
Local reactions, such as pain, itching, burning, and redness, may occur. If reactions are severe, discontinue use and consult your doctor.
Some people using IRUXOL MONO may experience other side effects. If you experience other side effects not listed in this leaflet, inform your doctor.
Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products, Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products
Al. Jerozolimskie 181C,
02-222 Warsaw
Phone: +48 22 49 21 301
Fax: +48 22 49 21 309
Website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
By reporting side effects, you can help provide more information on the safety of this medicine.

5. How to store IRUXOL MONO

Keep the medicine out of the sight and reach of children.
Store in a temperature below 25°C, in a dry place.
Do not use this medicine after the expiry date stated on the carton and tube. The expiry date refers to the last day of the month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

What IRUXOL MONO contains

  • The active substances are collagenase N (0.52 mg - 3.75 mg), with clostridiopeptidase A activity of not less than 1.2 j, and not less than 0.24 j of accompanying proteases.
  • The other ingredients are: liquid paraffin, white vaseline

What IRUXOL MONO looks like and contents of the pack

Tube in a carton box. IRUXOL MONO is available in packs containing 20 or 30 g of ointment.

Marketing Authorization Holder

Smith & Nephew GmbH
Friesenweg 30
22763 Hamburg
Germany

Manufacturer

Nordmark Pharma GmbH
Pinnauallee 4
D-25436 Uetersen
Germany
To obtain more detailed information, please contact the local representative of the marketing authorization holder:
Smith & Nephew Sp. z o.o.
ul. Osmańska 12
02-823 Warsaw
Phone: 22 360 41 20
Fax: 22 360 41 21

Date of last revision of the leaflet:

Alternatives to Iruxol Mono in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Iruxol Mono in Spain

Dosage form: GEL, 5 grams
Active substance: bromelains
Manufacturer: Mediwound Germany Gmbh
Prescription required
Dosage form: GEL, 2 grams
Active substance: bromelains
Manufacturer: Mediwound Germany Gmbh
Prescription required
Dosage form: OINTMENT, 0.6 IU / 3.5 mg
Active substance: collagenase, combinations
Manufacturer: Smith & Nephew Gmbh
Prescription required
Dosage form: OINTMENT, 1 G
Active substance: collagenase, combinations
Manufacturer: Smith & Nephew Gmbh
Prescription required

Online doctors for Iruxol Mono

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Iruxol Mono – subject to medical assessment and local rules.

0.0(1)
Doctor

Svetlana Kolomeeva

Cardiology17 years of experience

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

CameraBook a video appointment
€50
November 1009:00
November 1010:05
November 1011:10
November 1012:15
November 1013:20
More times
5.0(38)
Doctor

Yevgen Yakovenko

General surgery11 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

CameraBook a video appointment
€54
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Marianna Neshta

Endocrinology24 years of experience

Marianna Neshta is a medical doctor specialising in endocrinology and ultrasound diagnostics. She provides online consultations for adults, focusing on the diagnosis, treatment, and long-term management of endocrine disorders. Her approach includes personalised care plans, analysis of lab results and ultrasound scans, and evidence-based treatment.

Key areas of expertise:

  • Type 1 and Type 2 diabetes – diagnosis, therapy adjustment, CGM interpretation, and prevention of chronic complications
  • Obesity – treatment using both medication and lifestyle strategies, including modern GLP-1 medications and tailored follow-up plans
  • Thyroid disorders – ultrasound assessment, treatment planning, and management during pregnancy
  • Male hypogonadism – age-related or hormonal, including diagnostics and therapy
  • Metabolic syndrome, prediabetes, lipid disorders – risk assessment, lifestyle recommendations, and medical treatment
  • Calcium metabolism disorders – diagnosis and management of osteoporosis, hyperparathyroidism, and hypoparathyroidism
Dr Neshta applies current clinical guidelines and diagnostic tools, offering medical support adapted to each patient’s individual needs — all in an accessible online format.
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She specialises in consultations and ongoing support for a wide range of mental health concerns, including:

  • Mood disorders: depression, bipolar disorder, postpartum depression.
  • Anxiety disorders: generalised anxiety, OCD, panic attacks, phobias.
  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD).
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders.

She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

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Alexandra Alexandrova

General medicine8 years of experience

Dr Alexandra Alexandrova is a licensed general medicine doctor in Spain, specialising in trichology, nutrition, and aesthetic medicine. She offers online consultations for adults, combining a therapeutic approach with personalised care for hair, scalp, and overall health.

Areas of expertise:

  • Hair loss in women and men, postpartum hair loss, androgenetic and telogen effluvium.
  • Scalp conditions: seborrheic dermatitis, psoriasis, scalp irritation, dandruff.
  • Chronic conditions: hypertension, diabetes, metabolic disorders.
  • Online trichology consultation: customised treatment plans, nutritional support, hair growth stimulation.
  • Hair loss prevention: hormonal imbalance, stress factors, haircare strategies.
  • Routine health check-ups, prevention of cardiovascular and metabolic diseases.
  • Personalised nutritional advice to improve hair strength, skin health, and hormonal balance.
  • Aesthetic medicine: non-invasive strategies to enhance skin quality, tone, and metabolic wellness.

Dr Alexandrova follows an evidence-based and holistic approach: online consultations with a therapist and trichologist on Oladoctor provide professional support for hair, scalp, and overall health — all from the comfort of your home.

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