This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.

How to use Dobenox Forte

Package Leaflet: Information for the Patient

DOBENOX, 250 mg, coated tablets

DOBENOX Forte, 500 mg, coated tablets

Calcii dobesilas monohydricus

Read the package leaflet carefully before taking the medicine, as it contains important information for the patient.

This medicine should always be taken exactly as described in this package leaflet for the patient or as directed by a doctor or pharmacist.

This package leaflet should be kept in case it needs to be read again.
If advice or additional information is needed, a pharmacist should be consulted.
If the patient experiences any side effects, including any side effects not listed in this package leaflet, they should inform their doctor or pharmacist. See section 4.
If there is no improvement or the patient feels worse, they should contact their doctor.

Table of Contents of the Package Leaflet

1. What is Dobenox or Dobenox Forte and what is it used for
2. Important information before taking Dobenox or Dobenox Forte
3. How to take Dobenox or Dobenox Forte
4. Possible side effects
5. How to store Dobenox or Dobenox Forte
6. Package contents and other information

1. What is Dobenox or Dobenox Forte and what is it used for

The active substance of the medicine is calcium dobesilate monohydrate, which improves venous circulation and has a protective effect on blood vessels. It reduces the permeability of their walls and excessive blood and serum viscosity, preventing the formation of stasis and thrombosis in venous vessels.

Indications for Use

Symptomatic treatment of chronic venous insufficiency of the lower limbs (pain and nocturnal cramps in the legs, feeling of heaviness in the legs, paresthesia, edema, skin changes due to blood stasis), varicose veins of the lower limbs.
Symptomatic treatment of hemorrhoids.

2. Important Information Before Taking Dobenox or Dobenox Forte

When Not to Take Dobenox or Dobenox Forte

if the patient is allergic to calcium dobesilate monohydrate or any of the other ingredients of this medicine (listed in section 6).

Warnings and Precautions

Before starting treatment with Dobenox or Dobenox Forte, the patient should discuss it with their doctor or pharmacist.
The medicine should be used with caution if the patient has gastric or duodenal ulcer disease, or renal insufficiency.
The patient should stop taking the medicine immediately and contact their doctor if they experience symptoms such as fever, sore throat, difficulty swallowing, oral inflammation, nasal mucosa inflammation, genital or anal inflammation, as these may be symptoms of a serious disease - agranulocytosis.
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Dobenox or Dobenox Forte and Other Medicines

The patient should inform their doctor or pharmacist about all medicines they are currently taking or have recently taken, as well as any medicines they plan to take.

Dobenox or Dobenox Forte with Food and Drink

The medicine should be taken after meals to avoid or minimize gastrointestinal side effects.

Pregnancy and Breastfeeding

If the patient is pregnant or breastfeeding, or thinks they may be pregnant or plans to have a child, they should consult their doctor or pharmacist before taking this medicine.
The medicine is not recommended during the first trimester of pregnancy.
The medicine may be used during pregnancy only if, in the doctor's opinion, the benefit to the mother outweighs the potential risk to the fetus.
The medicine should not be used during breastfeeding.

Driving and Operating Machines

The medicine does not affect the ability to drive or operate machines.

Dobenox or Dobenox Forte Contains Lactose

If the patient has previously been diagnosed with intolerance to some sugars, they should contact their doctor before taking the medicine.
1 tablet of Dobenox contains 25 mg of lactose.
1 tablet of Dobenox Forte contains 50 mg of lactose.

3. How to Take Dobenox or Dobenox Forte

This medicine should always be taken exactly as described in this package leaflet for the patient or as directed by a doctor or pharmacist. If in doubt, the patient should consult their doctor or pharmacist.
The medicine is taken orally.
The medicine should be taken after meals.

Dobenox, 250 mg, Coated Tablets

Unless otherwise directed by a doctor, the usual dose for adults is 2 to 4 tablets per day (corresponding to a daily dose of 500 mg to 1000 mg of the active substance - calcium dobesilate monohydrate):
venous insufficiency - usually 2 tablets 1-2 times a day;
hemorrhoids - usually 2 tablets 1-2 times a day.

Dobenox Forte, 500 mg, Coated Tablets

Unless otherwise directed by a doctor, the usual dose for adults is 1 to 2 tablets per day (corresponding to a daily dose of 500 mg to 1000 mg of the active substance - calcium dobesilate monohydrate):
venous insufficiency - usually 1 to 2 tablets per day;
hemorrhoids - usually 1 to 2 tablets per day.
In case of doubt, the patient should consult their doctor or pharmacist.
Treatment may last from several weeks to several months, depending on the indications.

Taking a Higher Dose of Dobenox or Dobenox Forte Than Recommended

There are no known symptoms of overdose.
In case of taking a higher dose of the medicine than recommended, the patient should immediately consult their doctor or pharmacist.
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Missing a Dose of Dobenox or Dobenox Forte

The patient should not take a double dose to make up for a missed dose.

Stopping Treatment with Dobenox or Dobenox Forte

In case of any further doubts about taking this medicine, the patient should consult their doctor or pharmacist.

4. Possible Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
The listed side effects usually disappear on their own after stopping treatment.
Uncommon side effects (occurring in 1 to 10 patients out of 10,000):
nausea, diarrhea,
skin reactions,
joint pain.
Rare side effects (occurring in less than 1 patient out of 10,000):
agranulocytosis - an acute condition that may manifest as high fever, infections in the mouth, sore throat, changes in the anus and genital area.

If Any of These Symptoms or Other Infection Symptoms Occur, the Patient Should Stop Taking the Medicine and Consult Their Doctor Immediately.

Reporting Side Effects

If the patient experiences any side effects, including any side effects not listed in this package leaflet, they should inform their doctor or pharmacist. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products
Aleje Jerozolimskie 181C, 02-222 Warsaw
tel.: 22 49 21 301, fax: 22 49 21 309
Website: https://smz.ezdrowie.gov.pl.
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help gather more information on the safety of the medicine.

5. How to Store Dobenox or Dobenox Forte

Store in the original packaging, at a temperature below 25°C.
The medicine should be stored out of sight and reach of children.
Do not use this medicine after the expiry date stated on the packaging. The expiry date refers to the last day of the specified month.
Medicines should not be disposed of via wastewater or household waste. The patient should ask their pharmacist how to dispose of medicines that are no longer needed. This will help protect the environment.
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6. Package Contents and Other Information

What Dobenox or Dobenox Forte Contains

The active substance of the medicine is calcium dobesilate monohydrate.
1 tablet contains 250 mg or 500 mg of calcium dobesilate monohydrate.
The other ingredients (excipients) are: microcrystalline cellulose, potato starch, lactose monohydrate, talc, magnesium stearate, colloidal silica anhydrous, Opadry II 57U18539 White coating containing: hypromellose, polydextrose, titanium dioxide (E 171), talc, maltodextrin, medium-chain triglycerides.

What Dobenox or Dobenox Forte Looks Like and What the Package Contains

Dobenox
Coated tablets - round, biconvex, white, with a uniform and smooth surface.
One package of Dobenox contains 30 coated tablets.
Dobenox Forte
Coated tablets - oval, biconvex, white, with a uniform and smooth surface.
One package of Dobenox Forte contains 30 or 60 coated tablets.

Marketing Authorization Holder and Manufacturer

“PRZEDSIĘBIORSTWO PRODUKCJI FARMACEUTYCZNEJ HASCO-LEK” S.A.
51-131 Wrocław, ul. Żmigrodzka 242 E
Information about the medicine
tel. 22 742 00 22
e-mail: [email protected]
Date of Last Update of the Package Leaflet:03/2024
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Country of registration
Poland
Active substance
calcium dobesilate
Prescription required
No
Importer
Przedsiębiorstwo Produkcji Farmaceutycznej HASCO-LEK S.A.
This information is for reference only and does not constitute medical advice. Always consult a licensed doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
Alternatives to Dobenox Forte
Adproctin
Dosage form: Capsules, 500 mg
Active substance: calcium dobesilate
Manufacturer: Farmaceutyczna Spółdzielnia Pracy "Galena"
Prescription not required
Calcium dobesilate Galena
Dosage form: Tablets, 250 mg
Active substance: calcium dobesilate
Manufacturer: Farmaceutyczna Spółdzielnia Pracy "GALENA"
Prescription required
Calcium dobesilate Hasco
Dosage form: Tablets, 250 mg
Active substance: calcium dobesilate
Prescription required

Alternatives to Dobenox Forte in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Dobenox Forte in Spain

DOXIUM FUERTE 500 mg HARD CAPSULES

Dosage form: CAPSULE, 500 mg

Active substance: calcium dobesilate

Manufacturer: Esteve Pharmaceuticals S.A.

Prescription required

FEPARIL 10mg/g + 50mg/g GEL

Dosage form: GEL, 10 mg escin; 50 mg diethylamine salicylate/1 g

Manufacturer: Cooper Consumer Health B.V.

Prescription not required

Online doctors for Dobenox Forte

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Dobenox Forte – subject to medical assessment and local rules.

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Dmytro Horobets

Family medicine6 years of experience

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Dr. Eteri Tabeshadze is a cardiologist with the highest qualification category and over 32 years of clinical experience. She also practises functional diagnostics, offering a comprehensive approach to cardiovascular care. Dr. Tabeshadze provides online consultations for adults with a wide range of heart-related conditions, from preventive screenings to acute and chronic disease management.

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Family medicine10 years of experience

Dr Liudmyla Boichuk is a family medicine doctor providing diagnosis and treatment for a wide range of acute and chronic conditions in adults and children. She works with respiratory, cardiovascular and digestive system disorders and has extensive experience caring for patients with multiple coexisting conditions, where coordinated, whole-person management is essential.

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Cardiology17 years of experience

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

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Endocrinology10 years of experience

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Rheumatology25 years of experience

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General medicine8 years of experience

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