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Dih

Dih

Ask a doctor about a prescription for Dih

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Dih

Package Leaflet: Information for the Patient

DIH

500 mg, coated tablets

Diosminum

Read the package leaflet carefully before taking the medicine, as it contains important information for the patient.

This medicine should always be taken exactly as described in this package leaflet for the patient or as advised by a doctor or pharmacist.

  • This leaflet should be kept in case it needs to be read again.
  • If advice or additional information is needed, a pharmacist should be consulted.
  • If the patient experiences any side effects, including any possible side effects not listed in this leaflet, they should inform their doctor or pharmacist. See section 4.
  • If there is no improvement or the patient feels worse, they should contact their doctor.

Table of Contents of the Leaflet

  • 1. What is DIH and what is it used for
  • 2. Important information before taking DIH
  • 3. How to take DIH
  • 4. Possible side effects
  • 5. How to store DIH
  • 6. Package contents and other information

1. What is DIH and what is it used for

DIH coated tablets contain diosmin, a compound belonging to the so-called bioflavonoids.
DIH increases venous vessel tension and has a protective effect on vessels.

Indications for Use

  • Symptoms of chronic venous insufficiency of the lower limbs:
    • pains and nocturnal cramps in the legs,
    • feeling of burning in the legs,
    • feeling of cold legs,
    • feeling of heaviness in the legs, fatigue, discomfort, or restless legs,
    • varicose veins of the lower limbs,
    • venous ulcers,
    • enlargement of very small venous vessels, so-called spider veins and reticular varices,
    • leg swelling (edema / swelling of the legs),
    • itching, paresthesia (tingling),
    • redness (erythema) or cyanosis of the skin.
  • Symptomatic treatment of hemorrhoids.
  • Monotherapy in the initial stages of chronic venous insufficiency or as a supplement to other therapies in all stages of chronic venous disease (C0-C6 according to the CEAP classification).

2. Important Information Before Taking DIH

When Not to Take DIH

  • If the patient is allergic to diosmin or any of the other ingredients of this medicine (listed in section 6).

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Warnings and Precautions

Before starting to take DIH, the patient should discuss it with their doctor or pharmacist.
In cases of exacerbation of symptoms caused by hemorrhoids, it should be remembered that the therapy with DIH is only symptomatic and should be short-term. If the symptoms do not subside, a comprehensive assessment of the patient's condition by a doctor is required.

DIH and Other Medicines

The patient should inform their doctor or pharmacist about all medicines they are currently taking or have recently taken, as well as any medicines they plan to take.
No interaction studies have been conducted.

DIH with Food and Drink

The medicine should be taken during meals.

Pregnancy and Breastfeeding

If the patient is pregnant or breastfeeding, thinks they may be pregnant, or plans to have a child, they should consult their doctor or pharmacist before taking this medicine.
Due to the lack of sufficient data, DIH may only be used during pregnancy if absolutely necessary.
It is not known whether the medicine passes into breast milk, so breastfeeding should be avoided during treatment.

Driving and Operating Machines

Taking DIH does not affect the ability to drive or operate machines.

3. How to Take DIH

This medicine should always be taken exactly as described in this package leaflet for the patient or as advised by a doctor or pharmacist. In case of doubts, the patient should consult their doctor or pharmacist.
The medicine is taken orally.
Usually, the recommended dose is two tablets a day during meals, i.e., one tablet in the morning and one in the evening (which corresponds to a daily dose of 1000 mg of diosmin, in two divided doses of 500 mg each).
Only in cases of exacerbation of symptoms caused by hemorrhoids is a higher dose of up to 6 tablets a day recommended, i.e., 2 times a day, 3 tablets for 4 days, and then a reduced dose: 4 tablets a day, i.e., 2 times a day, 2 tablets.

Taking a Higher Than Recommended Dose of DIH

In case of taking a significantly higher dose of the medicine than recommended, the patient should consult their doctor or pharmacist.
No symptoms of overdose are known.

Missing a Dose of DIH

The patient should not take a double dose to make up for a missed dose.
If a dose of DIH is missed, the patient should take the dose with the next meal: if they forgot to take the medicine in the morning, they should take it at noon, and the next dose should be taken as planned, i.e., in the evening.
In case of any further doubts about taking this medicine, the patient should consult their doctor or pharmacist.
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4. Possible Side Effects

Like all medicines, DIH can cause side effects, although not everybody gets them.
Rarely(in 1 to 10 patients out of 10,000):
gastrointestinal disorders,
nausea,
vomiting,
dizziness, headache,
malaise,
rash, itching, urticaria.
In the case of mild side effects related to the stomach and intestines, as well as neurovegetative disorders (insomnia, difficulty falling asleep, dizziness, and headaches, anxiety), it is not necessary to discontinue the medicine.

Reporting Side Effects

If any side effects occur, including any possible side effects not listed in this leaflet, the patient should inform their doctor or pharmacist. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products
Al. Jerozolimskie 181 C, 02-222 Warsaw,
tel. +48 22 49 21 301, fax: + 48 22 49 21 309,
Website: https://smz.ezdrowie.gov.pl
Side effects can also be reported to the marketing authorization holder.
Reporting side effects will help gather more information on the safety of the medicine.

5. How to Store DIH

Store in the original package, at a temperature below 25°C.
The medicine should be stored out of sight and reach of children.
Do not use this medicine after the expiry date stated on the package.
The expiry date refers to the last day of the given month.
Medicines should not be disposed of via wastewater or household waste. The patient should ask their pharmacist how to dispose of medicines that are no longer needed. This will help protect the environment.

6. Package Contents and Other Information

What DIH Contains

  • The active substance of the medicine is micronized diosmin. One coated tablet contains 500 mg of micronized diosmin.
  • The other ingredients (excipients) are: microcrystalline cellulose, povidone, sodium carboxymethyl cellulose, magnesium stearate, Opadry II 85F24220 Pink coating [polyvinyl alcohol, titanium dioxide (E 171), Macrogol - PEG 3350, talc, yellow iron oxide (E 172), and red iron oxide (E 172)].

What DIH Looks Like and What the Package Contains

DIH is an oval, pink, coated tablet with a smooth surface.
One package of the medicine contains 30, 60, or 90 tablets, in a cardboard box.
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Marketing Authorization Holder and Manufacturer

“PRZEDSIĘBIORSTWO PRODUKCJI FARMACEUTYCZNEJ HASCO-LEK” S.A.
51-131 Wrocław, ul. Żmigrodzka 242 E

Medicine Information

tel.: 22 742 00 22
e-mail: [email protected]

Date of Last Update of the Leaflet:

4/4

Alternatives to Dih in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Dih in Ukraine

Dosage form: tablets, tablets 600mg
Active substance: diosmin
Manufacturer: Fiteo Laboratuar
Prescription not required
Dosage form: tablets, film-coated tablets, 600 mg
Active substance: diosmin
Manufacturer: Innotera Suzi
Prescription not required
Dosage form: tablets, 500mg tablets in blister
Active substance: diosmin
Manufacturer: KRKA, d.d., Novo mesto
Prescription not required
Dosage form: tablets, 1000 mg tablets in blister
Active substance: diosmin

Alternative to Dih in Spain

Dosage form: TABLET, Diosmin 450 mg / Hesperidin 50 mg
Active substance: diosmin, diosmin, combinations
Manufacturer: Kern Pharma S.L.
Prescription not required
Dosage form: TABLET, 1000 mg
Active substance: diosmin
Prescription not required
Dosage form: TABLET, 1000 mg
Active substance: diosmin
Prescription not required
Dosage form: CAPSULE, 200 mg
Active substance: hidrosmin
Manufacturer: Faes Farma S.A.
Prescription not required
Dosage form: GEL, 20 mg/g
Active substance: hidrosmin
Manufacturer: Faes Farma S.A.
Prescription not required
Dosage form: CAPSULE, 200 mg
Active substance: hidrosmin
Manufacturer: Faes Farma S.A.
Prescription required

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