Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

12+ years of clinical experience in university hospitals in Germany and Spain.
International education: Ukraine – Germany – Spain.
Member of the German Society of Surgeons (BDC).
Certified in radiological diagnostics and robotic surgery.
Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.

How to use KODEPSIN

INSTRUCTIONS for medical use of the medicinal product LIOGEL 1000

Composition

The active substance: 1 g of gel contains sodium heparin in terms of 100% substance 1000 IU; excipients: ethanol 96%, methylparaben (methylhydroxybenzoate) (E 218), carbomers, tromethamine, lavender oil, neroli oil, purified water.

Pharmaceutical form

Gel for external use.

Main physical and chemical properties

Transparent or almost transparent, colorless or with a slightly yellowish tint gel with a specific odor. It should be homogeneous in appearance.

Pharmacotherapeutic group

Agents used for varicose vein enlargement.

ATC code C05V A03.

Pharmacological properties

Pharmacodynamics

LioGel 1000, when applied to the skin, has anti-edematous, anti-exudative, anti-inflammatory, and anticoagulant effects.

Pharmacokinetics

Heparin is detected in plasma within 24 hours after application of the preparation, with the peak concentration of heparin reached after 8 hours. Excretion occurs mainly through the kidneys. The preparation applied to the skin does not affect blood coagulation parameters.

Clinical characteristics

Indications

Treatment of superficial vein diseases, such as varicose vein enlargement and related complications, phlebothrombosis, thrombophlebitis, superficial periphlebitis. Postoperative varicose phlebitis, complications after surgical removal of the subcutaneous vein of the leg. Injuries and hematomas, infiltrates, and localized edema, subcutaneous hematomas. Injuries and stretching of muscle-tendon and capsular-ligamentous structures.

Contraindications

Increased sensitivity to heparin or other components of the preparation, trophic ulcers of the legs that bleed, open and/or infected wounds, hemorrhagic diathesis, purpura, thrombocytopenia, hemophilia. Tendency to bleeding.

Interaction with other medicinal products and other types of interactions

The use of heparin can contribute to the prolongation of prothrombin time in patients taking oral anticoagulants. The preparation should not be used together with topical preparations, such as those containing tetracycline, hydrocortisone, salicylic acid, or anticoagulants.

Special instructions

As an excipient, the medicinal product contains methylhydroxybenzoate, so it should not be used in patients with an allergy to parabens. If the patient has hemorrhagic symptoms, the possibility of using the LioGel 1000 preparation should be carefully weighed. The preparation should not be prescribed for bleeding, applied to open wounds, infected skin areas with purulent processes, mucous membranes, eyes, and areas around the eyes, or to ulcers and blisters. In case of blood coagulation disorders, the gel is not recommended to be applied to large areas of skin. In the treatment of phlebitis, this medicinal product should not be rubbed into the skin.

Use during pregnancy or breastfeeding

Data on the use of the preparation during pregnancy or breastfeeding are not available.

Ability to affect the speed of reaction when driving vehicles or operating machinery

The preparation does not affect the ability to drive vehicles or operate machinery.

Method of administration and dosage

Adults should use the preparation 1-3 times a day. Apply 3-10 cm of gel to the affected skin area and gently rub in. The duration of treatment is determined by the doctor individually, taking into account the severity of the disease.

Children

Due to limited experience with the use of the preparation, it should not be prescribed to children.

Overdose

Overdose symptoms have not been described to date. Due to the low systemic absorption, the risk of overdose of the preparation for local use is absent. In the event of accidental oral administration of the gel (e.g., by a child), nausea or vomiting may occur. In this case, the stomach should be rinsed, and if necessary, symptomatic therapy should be prescribed. The action of heparin can be neutralized with protamine sulfate.

Adverse reactions

In individual cases, hypersensitivity reactions may occur, such as redness, itching, and swelling of the skin, burning sensation, skin rash, urticaria, angioedema, hemorrhages, and sometimes the formation of small pustules, blisters, or bubbles that quickly resolve after discontinuation of the preparation. When applied to large areas of skin, systemic side effects are possible.

Shelf life

3 years.

Do not use the preparation after the expiration date stated on the packaging.

Storage conditions

Store in the original packaging at a temperature not exceeding 25 °C.

Store in a place inaccessible to children.

Packaging

30 g, 50 g, or 100 g in a tube; 1 tube in a pack.

Release category

Over-the-counter.

Manufacturer

PRJSC "FITOFARM".

Location of the manufacturer and its address

Ukraine, 84500, Donetsk region, Bakhmut, Sibirceva street, 2.

Applicant

PRJSC "FITOFARM".

Location of the applicant and/or representative of the applicant

Ukraine, 02092, Kyiv, Almatinskaya street, 12.

KODEPSIN

Yevgen Yakovenko

Nuno Tavares Lopes