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ALGEZIKAM

ALGEZIKAM

Ask a doctor about a prescription for ALGEZIKAM

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use ALGEZIKAM

INSTRUCTIONS for medical use of the medicinal product ADASUVE

ADASUVE (ADASUVE)

Composition

active substance: loxapine; 1 dose contains 10.0 mg of loxapine base, which corresponds to a delivered dose of 9.1 mg of loxapine.

Pharmaceutical form

Powder for inhalation, dosed.

Main physical and chemical properties

white plastic body and activation insert without visible defects.

Pharmacotherapeutic group

Agents acting on the nervous system. Psychotropic agents. Antipsychotic agents. Diazepines, oxazepines, thiazepines, and oxepines. ATC code N05A H01.

Pharmacological properties

Pharmacodynamics

The efficacy of loxapine is believed to be mediated by its high-affinity antagonism of dopamine D2 receptors and serotonin 5-HT2A receptors. Loxapine binds to noradrenergic, histaminergic, and cholinergic receptors, and this interaction may influence the spectrum of its pharmacological effects.

Pharmacokinetics

Absorption. After administration of the Adasuv preparation, rapid absorption of loxapine was noted; the median time to reach its maximum concentration in plasma (Tmax) is 2 minutes.

Clinical characteristics

Indications

For the rapid regulation of agitation from mild to moderate degree in adult patients with schizophrenia or bipolar disorders.

Contraindications

Increased sensitivity to the active substance or amoxapine. Presence of acute respiratory symptoms, such as stridor, or respiratory diseases, including bronchial asthma or chronic obstructive pulmonary disease (COPD).

Interaction with other medicinal products and other types of interactions

Concomitant use of benzodiazepines or other hypnotic-sedative agents, or respiratory depressants may be associated with increased sedation and respiratory depression or respiratory failure.

Special instructions

Proper use of the Adasuv inhaler

is important for the administration of the full dose of loxapine. Medical personnel should ensure that the patient uses the inhaler correctly.

Bronchospasm

During placebo-controlled clinical trials involving patients with bronchial asthma or COPD, bronchospasm was very frequently observed, which usually developed within 25 minutes after administration of the preparation.

Overdose

During clinical trials, no overdose with Adasuv was reported. In case of accidental overdose, symptoms will depend on the amount of the preparation taken and the individual patient's tolerance.

Adverse reactions

The assessment of adverse reactions is based on data from short-term (24-hour) placebo-controlled clinical trials (two phase 3 studies and one phase 2A study) involving 524 adult patients with agitation associated with schizophrenia (including 27 patients with schizoaffective disorders) or bipolar disorders, using the Adasuv preparation.

Shelf life

4 years.

Storage conditions

No special storage conditions are required. Store in the original packaging. Store in a place inaccessible to children.

Packaging

One foil pack with one Staccato inhaler in a cardboard pack.

Release category

Prescription only.

Manufacturer

Ferrer Internacional, S.A., Spain.

Manufacturer's location and address

Joan Buscalla, 1-9, Sant Cugat del Valles, Barcelona, 08173, Spain.

Alternatives to ALGEZIKAM in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to ALGEZIKAM in Poland

Dosage form: Solution, 15 mg/1.5 ml
Active substance: meloxicam
Marketing authorisation holder (MAH): Zentiva, k.s.
Prescription required
Dosage form: Solution, 15 mg/1.5 ml
Active substance: meloxicam
Marketing authorisation holder (MAH): Zentiva, k.s.
Prescription required
Dosage form: Tablets, 15 mg
Active substance: meloxicam
Importer: Przedsiębiorstwo Produkcji Farmaceutycznej HASCO-LEK S.A.
Prescription required
Dosage form: Solution, 10 mg/ml (15 mg/1.5 ml)
Active substance: meloxicam
Marketing authorisation holder (MAH): Boehringer Ingelheim International GmbH
Prescription required
Dosage form: Solution, 10 mg/ml (15 mg/1.5 ml)
Active substance: meloxicam
Marketing authorisation holder (MAH): Boehringer Ingelheim RCV GmbH & Co KG
Prescription required
Dosage form: Solution, 10 mg/ml (15 mg/1.5 ml)
Active substance: meloxicam
Marketing authorisation holder (MAH): Boehringer Ingelheim International GmbH
Prescription required

Alternative to ALGEZIKAM in Spain

Dosage form: TABLET, 7.5 mg
Active substance: meloxicam
Prescription required
Dosage form: TABLET, 15 mg
Active substance: meloxicam
Prescription required
Dosage form: TABLET, 15 mg
Active substance: meloxicam
Prescription required
Dosage form: TABLET, 7.5 mg
Active substance: meloxicam
Prescription required
Dosage form: TABLET, 15 mg
Active substance: meloxicam
Prescription required
Dosage form: TABLET, 7.5 mg
Active substance: meloxicam
Manufacturer: Laboratorio Stada S.L.
Prescription required

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Discuss dosage, side effects, interactions, contraindications, and prescription renewal for ALGEZIKAM – subject to medical assessment and local rules.

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Antonio Cayatte

General medicine44 years of experience

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Rheumatology26 years of experience

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Alexander Nazarchuk

Allergology7 years of experience

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

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During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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