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OPTALIDON 500 mg/75 mg Suppositories

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About the medicine

How to use OPTALIDON 500 mg/75 mg SUPPOSITORIES

Contents of the leaflet

  1. Introduction
  2. What Optalidon is and what it is used for
  3. What you need to know before taking Optalidon
  4. How to take Optalidon
  5. Possible side effects
  6. Storage of Optalidon
  7. Package contents and additional information

Introduction

Patient Information Leaflet

Optalidon 500 mg/75mg suppositories Propyphenazone, anhydrous caffeine

Read this leaflet carefully before starting to use this medicine, as it contains important information for you.

Follow the administration instructions for the medicine contained in this leaflet or as indicated by your doctor or pharmacist exactly.

  • Keep this leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve after 10 days.

Contents of the Leaflet

  1. What Optalidon is and what it is used for
  2. What you need to know before taking Optalidon
  3. How to take Optalidon
  4. Possible side effects
  5. Storage of Optalidon
  6. Package contents and additional information

1. What Optalidon is and what it is used for

Optalidon is a medicine that contains two active ingredients in combination: propyphenazone for pain, and caffeine, which has a stimulating effect on the nervous system, for somnolence.

It is indicated for adults and children over 12 years old, for the relief of mild or moderate pain, such as headache, toothache, and menstrual pain.

You should consult a doctor if it worsens or does not improve after 10 days.

Doctor consultation

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2. What you need to know before taking Optalidon

Do not useOptalidon

  • If you are allergic to propyphenazone or caffeine, or to any of the other components of this medicine (listed in section 6).
  • If you are allergic to medicines that contain metamizole, phenylbutazone, or other components of the pyrazolone group.
  • If you are allergic to medicines that contain aminophylline, dyphylline, oxtriphylline, theobromine, theophylline, or other components of the xanthine group.
  • If you have experienced allergic reactions of an asthmatic type (difficulty breathing, shortness of breath, bronchospasm, and in some cases cough or wheezing) when taking acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.
  • If you have blood disorders (granulocytopenia, agranulocytosis).
  • If you have any metabolic disease such as porphyria (a rare, usually hereditary disorder in which a large amount of porphyrin is eliminated in feces and urine) or congenital glucose-6-phosphate dehydrogenase deficiency.
  • If you have severe liver, kidney, or heart disease (renal, hepatic, or cardiac insufficiency).
  • If you have an anxiety disorder.
  • If you have an active gastroduodenal ulcer.

Warnings and precautions

Consult your doctor or pharmacist before starting to use Optalidon.

Do not exceed the recommended dose in the Posology section, nor use it for more than 10 days. Consult your doctor or pharmacist before starting to use Optalidon if:

  • you have hypertension,
  • you have a gastroduodenal ulcer,
  • you have asthma or severe respiratory diseases (chronic obstructive pulmonary disease, emphysema, chronic bronchitis).

If the pain persists, worsens, or other symptoms appear, especially fever or mouth ulcers, treatment should be discontinued immediately and your doctor consulted.

Caffeine may increase blood glucose levels.

In people with sleep disorders, it is recommended not to take this medicine in the hours before bedtime to avoid possible insomnia.

Athletes should be informed that this medicine contains a component that may result in a positive doping test.

Children and adolescents

It should not be administered to children under 12 years old.

Other medicines and Optalidon

Taking Optalidon with other medicines.

Inform your doctor or pharmacist if you are taking or using, have taken or used recently, or may need to take or use any other medicine. In particular, if you are taking any of the following medicines, it may be necessary to modify the dose of one of them or interrupt treatment:

  • oral anticoagulants (medicines used to "thin" the blood and prevent clot formation) such as warfarin,
  • barbiturics (medicines used to treat seizures),
  • antihistamines (used to reduce the symptoms of allergic reactions),
  • lithium (reducing its therapeutic effect).

Using Optalidon with food and beverages and alcohol

It is recommended to limit the use of products that contain caffeine when being treated with this medicine.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine. This medicine should not be taken during pregnancy or breastfeeding without consulting a doctor.

Do not take Optalidon if you are in the last 3 months of pregnancy, as it may harm the fetus or cause problems during delivery. It may cause kidney and heart problems in the fetus. It may affect your tendency and that of the fetus to bleed and make labor longer than expected. You should not take Optalidon during the first 6 months of pregnancy unless it is absolutely necessary and indicated by your doctor. If you need treatment during this period or while trying to become pregnant, you should use the lowest dose for the shortest possible time. If you take it for more than a few days from the 20th week of pregnancy, Optalidon may cause kidney problems in the fetus, which can lead to low levels of amniotic fluid surrounding the fetus (oligohydramnios) or narrowing of a blood vessel (ductus arteriosus) in the baby's heart. If you need treatment for more days, your doctor may recommend additional monitoring.

Driving and using machines

Do not drive or operate hazardous machinery, as this medicine can cause drowsiness or decreased reaction time at the recommended doses.

3. How to take Optalidon

Follow the administration instructions for this medicine indicated by your doctor or pharmacist exactly. If in doubt, consult your doctor or pharmacist again.

Rectal route.

The recommended dose is 1 suppository per day. The maximum dose will be 2 suppositories per day.

Always use the lowest effective dose. Administration of the preparation is subject to the appearance of pain. As it disappears, this medication should be discontinued.

Instructions for correct administration of the preparation

If the suppository is too soft to insert, cool it in the refrigerator for 30 minutes or put it under cold running water before removing the plastic wrapper or after if necessary to prevent it from softening.

Use in children and adolescents

It should not be used in children under 12 years old.

If you use more Optalidon than you should

Symptoms of overdose are: abdominal pain, nausea, vomiting, drowsiness, excitement, convulsions, and coma.

In case of overdose or accidental ingestion, go immediately to a medical center or call the Toxicology Information Service (Telephone: (91)-562.04.20), indicating the medicine and the amount ingested.

If you forget to use Optalidon

Do not use a double dose to make up for forgotten doses.

If you stop treatment with Optalidon

If you have any other doubts about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everyone gets them.

They are not usually observed at the recommended doses. In hypersensitive subjects, very rare cutaneous allergic reactions have been observed: redness or itching, skin alterations with blister formation, urticaria, or shock. In this case, treatment should be discontinued and a doctor consulted. Occasionally, dizziness, nausea, nervousness, difficulty sleeping, rapid heartbeats, or gastrointestinal irritation may appear.

Reporting side effects

If you experience any type of side effect, consult your doctor or pharmacist, even if it is a possible side effect not listed in this leaflet. You can also report them directly through the Spanish Medicines and Health Products Agency's website: www.notificaram.es.

By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Optalidon

Keep this medicine out of the sight and reach of children. No special storage conditions are required.

Do not use this medicine after the expiration date shown on the label and carton after CAD. The expiration date is the last day of the month indicated.

Medicines should not be disposed of through wastewater or household waste. Deposit the packaging and medicines you no longer need at the pharmacy's SIGRE point. Ask your pharmacist how to dispose of the packaging and medicines you no longer need. This will help protect the environment.

6. Package contents and additional information

Composition of Optalidon

Per suppository:

The active ingredients are propyphenazone (DCI) 500 mg, anhydrous caffeine 75 mg.

The other components (excipients) are yellow iron oxide, red iron oxide, Sorbitan laurate (Span 20), and suppository mass.

Appearance of the product and package contents

Package with 6 suppositories.

Marketing authorization holder

Perrigo España S.A.

Pza de Xavier Cugat 2 Edificio D planta 1 08174 Sant Cugat del Valles

Barcelona, Spain

Manufacturer

MIPHARM S.P.A.,

Via B. Quaranta, 12, 1-201 40, Italy

Date of the last revision of this leaflet: 12/2022

Other sources of information

Detailed information about this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es.

Online doctors for OPTALIDON 500 mg/75 mg SUPPOSITORIES

Discuss questions about OPTALIDON 500 mg/75 mg SUPPOSITORIES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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€72
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5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(20)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

Get OPTALIDON 500 mg/75 mg SUPPOSITORIES Prescription Online

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Frequently Asked Questions

OPTALIDON 500 mg/75 mg SUPPOSITORIES does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in OPTALIDON 500 mg/75 mg SUPPOSITORIES is propyphenazone, combinations excl. psycholeptics. This information helps identify medicines with the same composition but different brand names.

OPTALIDON 500 mg/75 mg SUPPOSITORIES is manufactured by Perrigo Espana S.A.. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether OPTALIDON 500 mg/75 mg SUPPOSITORIES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy OPTALIDON 500 mg/75 mg SUPPOSITORIES in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

Other medicines with the same active substance (propyphenazone, combinations excl. psycholeptics) include METALGIAL 500 MG/ML ORAL DROPS IN SOLUTION, METAMIZOLE ABABOR 575 mg HARD CAPSULES, METAMIZOL AIKO FARMACEUTICA 575 mg HARD CAPSULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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