


Ask a doctor about a prescription for ACENAM 1250 mg EFFERVSCENT TABLETS
Leaflet:information for the patient
Acenam 1250 mg effervescent tablets
Glucosamine
Read the entire leaflet carefully before starting to take this medication, as it contains important information for you.
Contents of the leaflet
Glucosamine belongs to the group of medications called other anti-inflammatory agents and non-steroidal anti-rheumatics.
Each Acenam 1250 mg effervescent tablet contains 1500 mg of glucosamine hydrochloride, equivalent to 1250 mg of glucosamine.
Acenam is indicated to relieve symptoms produced by mild to moderate knee osteoarthritis
Do not take Acenam:
Warnings and precautions
Consult your doctor, pharmacist, or nurse before starting to take Acenam.
Using Acenam with other medications
Inform your doctor or pharmacist if you are taking, have recently taken, or may need to take any other medication.
Certain medications may interact with Acenam. In these cases, it may be necessary to change the dose or interrupt treatment with one of the medications.
Caution is recommended if Acenam is administered in combination with other medications, especially:
Consult your doctor.
Taking Acenam with food, beverages, and alcohol
You can take the tablets with or without food.
Pregnancy, breastfeeding, and fertility
If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medication.
Acenam should not be used during pregnancy.
The use of glucosamine is not recommended during breastfeeding.
Driving and using machines
No studies have been conducted on how Acenam affects the ability to drive and use machines.
However, if you experience dizziness or drowsiness due to the tablets, you should not drive or operate machinery.
Acenam contains sorbitol (E-420) and sodium
This medication contains 295 mg of sorbitol in each tablet.
This medication contains 318.2 mg of sodium (main component of table salt) in each tablet, equivalent to 16% of the maximum recommended daily sodium intake for an adult.
Follow the administration instructions for this medication exactly as indicated by your doctor or pharmacist. If in doubt, consult your doctor or pharmacist again.
The initial dose is 1250 mg of glucosamine (1 effervescent tablet) in a single daily dose for symptom relief.
Symptom relief is usually observed after four weeks of starting treatment. Glucosamine is not indicated for the treatment of acute painful symptoms. Once symptom relief is achieved, the dose can be reduced to 625 mg per day. If no improvement is observed after 2-3 months of treatment, the continuation of treatment with glucosamine should be reconsidered.
Acenam 1250 mg effervescent tablets are administered orally.
The tablets should be dissolved previously in half a glass of water. The resulting solution can be taken with or without food.
If you take more Acenam 1250 mg effervescent tablets than you should
Consult your doctor, pharmacist, or go to the nearest hospital or call the Toxicology Information Service, phone 91 562 0420, indicating the medication and the amount ingested.
Signs and symptoms of glucosamine overdose include headache, dizziness, confusion, joint pain, nausea, vomiting, diarrhea, or constipation.
If you forget to take Acenam 1250 mg effervescent tablets
Do not take a double dose to make up for forgotten doses.
Take your dose as soon as possible. If it is almost time for your next dose, wait until then to take your tablet.
Take your next dose according to your usual schedule.
If you interrupt treatment with Acenam 1250 mg effervescent tablets
If you have any other doubts about the use of this medication, ask your doctor, pharmacist, or nurse.
Symptoms may reappear.
If you have any other doubts about the use of this product, ask your doctor or pharmacist.
Like all medications, this medication can cause side effects, although not everyone experiences them.
The most commonly observed are:
You should interrupt glucosamine treatment and consult your doctor immediately if you experience symptoms of angioedema, such as:
The most frequently observed are:
Frequent (affects 1 to 10 of every 100 people)
Uncommon (affects 1 to 10 of every 1,000 people)
Frequency not known (cannot be estimated from available data)
Reporting side effects
If you experience any type of side effect, consult your doctor, pharmacist, or nurse, even if it is a possible side effect not listed in this leaflet. You can also report them directly through the Spanish Medication Surveillance System for Human Use: www.notificaram.es. By reporting side effects, you can contribute to providing more information on the safety of this medication.
Keep this medication out of the sight and reach of children.
Do not use ACENAM after the expiration date stated on the tube or box after the abbreviation CAD. The expiration date is the last day of the month indicated.
Store below 30°C.
Keep in the original packaging to protect from moisture.
Keep the container tightly closed.
Medications should not be disposed of through wastewater or household waste. Deposit the packaging and any unused medications in the SIGRE collection point at the pharmacy. If in doubt, ask your pharmacist how to dispose of the packaging and medications you no longer need. This will help protect the environment.
Composition of Acenam 1250 mg effervescent tablets
Appearance of the product and package contents
Acenam 1250 mg effervescent tablets are presented in the form of white effervescent tablets. Each package contains 30 tablets in 2 polypropylene tubes with a polyethylene cap equipped with a desiccant (silica gel) containing 15 effervescent tablets each, 20 tablets in 1 tube of 20 effervescent tablets, and packages of 40 tablets in two tubes of 20 effervescent tablets each.
Marketing authorization holder and manufacturer
Marketing authorization holder
Especialidades Farmacéuticas Centrum, S.A.
C/ Sagitario, 14
03006 Alicante, Spain
Manufacturer
E Pharma Trento S.p.A.
Via Provina, 2, I 38040 Ravina (Trento) Italy
Date of the last revision of this leaflet:May 2018.
Detailed and updated information on this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es/).
The average price of ACENAM 1250 mg EFFERVSCENT TABLETS in October, 2025 is around 8.68 EUR. Prices may vary depending on the region, pharmacy, and whether a prescription is required. Always check with a local pharmacy or online source for the most accurate information.
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Discuss dosage, side effects, interactions, contraindications, and prescription renewal for ACENAM 1250 mg EFFERVSCENT TABLETS – subject to medical assessment and local rules.