Zinnat
Ask a doctor about a prescription for Zinnat
How to use Zinnat
Leaflet accompanying the packaging: patient information
Warning! Keep the leaflet! Information on the immediate packaging in a foreign language.
Zinnat (Zinadol)
250 mg, coated tablets
Cefuroxime
Zinnat and Zinadol are different trade names for the same medicine.
You should carefully read the contents of the leaflet before taking the medicine, as it contains important information for the patient.
- You should keep this leaflet so that you can read it again if necessary.
- If you have any doubts, you should consult a doctor or pharmacist or nurse.
- This medicine has been prescribed specifically for you. Do not pass it on to others. The medicine may harm another person, even if their symptoms are the same.
- If the patient experiences any side effects, including any side effects not listed in this leaflet, they should tell their doctor, pharmacist, or nurse. See section 4.
Table of contents of the leaflet
- 1. What is Zinnat and what is it used for
- 2. Important information before taking Zinnat
- 3. How to take Zinnat
- 4. Possible side effects
- 5. How to store Zinnat
- 6. Contents of the pack and other information
1. What is Zinnat and what is it used for
Zinnat is an antibiotic used in adults and children. The medicine works by killing the bacteria that cause infections. It belongs to a group of medicines called cephalosporins.
Zinnat is used to treat infections:
- of the throat
- of the sinuses
- of the middle ear
- of the lungs or chest
- of the urinary tract
- of the skin and soft tissues. Zinnat may also be used:
- to treat early stages of Lyme disease (borreliosis - an infection transmitted by ticks).
The doctor may check what type of bacteria caused the patient's infection and check during treatment if the bacteria are sensitive to Zinnat.
2. Important information before taking Zinnat
When not to take Zinnat:
- if the patient is allergicto cefuroxime axetil, to any of the cephalosporin antibioticsor to any of the other ingredients of Zinnat (listed in section 6);
- if the patient has ever had a severe allergic reaction (hypersensitivity) to any other type of beta-lactam antibiotic (penicillins, monobactams, or carbapenems).
- if the patient has ever had a severe skin rash or peeling of the skin, blisters, and (or) ulcers of the mouth after treatment with cefuroxime or other cephalosporin antibiotics.
- If the above circumstances apply to the patient, they should not take Zinnatwithout consulting a doctor.
Warnings and precautions
Severe skin reactions have been reported with cefuroxime treatment, such as:
Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS). If any of the symptoms associated with severe skin reactions described in section 4 are observed, medical advice should be sought immediately.
Before starting Zinnat, the patient should discuss it with their doctor or pharmacist.
Children
Zinnat is not recommended for use in children under 3 months, as the safety and efficacy of the medicine in this age group are not known.
During treatment with Zinnat, attention should be paid to whether the following complaints occur: allergic reactions, fungal infections (e.g., with Candida), and severe diarrhea (pseudomembranous colitis). This will reduce the risk of complications. See “Complaints to watch out for”in section 4.
Blood tests
Zinnat may affect the results of blood sugar tests and a blood test called the Coombs test. If the patient is to have blood tests, they should:
- tell the person taking the blood samplethat they are taking Zinnat.
Zinnat and other medicines
The patient should tell their doctor or pharmacist about all medicines they are currently taking or have recently taken, as well as any medicines they plan to take.
- Medicines that reduce stomach acid(e.g., antacids used to treat heartburn) may affect the action of Zinnat.
- Probenecid.
- Oral anticoagulants (blood thinners).
- If the patient is taking any of the above (or similar) medicines, they should tell their doctor or pharmacist.
Pregnancy, breastfeeding, and fertility
If the patient is pregnant or breastfeeding, thinks they may be pregnant, or plans to have a child, they should consult their doctor or pharmacist before taking this medicine.
Driving and using machines
Zinnat may cause dizzinessand other side effects that can impair the patient's alertness.
- The patient should not drive or operate machineryif they do not feel well.
Important information about some ingredients of Zinnat
- Zinnat, 250 mg, coated tablets contain 0.00203 mg of sodium benzoate (E 211) per tablet.
- The medicine contains less than 1 mmol (23 mg) of sodium per tablet, which means the medicine is considered “sodium-free”.
- The patient should contact their doctorto see if Zinnat is a suitable medicine for them to take.
3. How to take Zinnat
This medicine should always be taken exactly as advised by the doctor or pharmacist. If the patient is unsure, they should consult their doctor or pharmacist again.
Zinnat is available in the following strengths: 125 mg, 250 mg, 500 mg.
Zinnat should be taken after a meal.This will help increase the effectiveness of the treatment.
Zinnat tablets should be swallowed whole with water.
The tablets should not be chewed, crushed, or divided- this may reduce the effectiveness of the treatment.
Recommended dose
Adults and children with a body weight of 40 kg or more
The recommended dose of Zinnat is 250 mg to 500 mg twice daily, depending on the severity and type of infection.
Children weighing less than 40 kg
Children under 40 kg should be treated with Zinnat in the form of an oral suspension.
The recommended dose of Zinnat is 10 mg/kg body weight (not more than 250 mg) to 15 mg/kg body weight (not more than 250 mg) twice daily, depending on:
- the severity and type of infection.
Zinnat is not recommended for use in children under 3 months, as the safety and efficacy of the medicine in this age group are not known.
Depending on the disease and how the patient responds to treatment, the initial dose may be changed or more than one treatment cycle may be necessary.
Patients with kidney problems
If the patient has kidney problems, the doctor may change the dose of Zinnat.
- If this applies to the patient, they should tell their doctor.
Taking more Zinnat than recommended
If the patient takes more Zinnat than recommended, they may experience neurological disorders, in particular an increased risk of seizures(epileptic fits).
- The patient should contact their doctor or call the emergency services immediately.If possible, they should show the Zinnat packaging.
Missing a dose of Zinnat
The patient should not take a double dose to make up for a missed dose.They should take the next dose at the usual time.
Stopping Zinnat treatment
The patient should not stop taking Zinnat unless their doctor advises them to do so.
It is important not to shorten the prescribed treatment period with Zinnat.The patient should not stop treatment without their doctor's advice, even if they feel better. Shortening the recommended treatment period may lead to a recurrence of the disease.
If the patient has any further doubts about taking this medicine, they should consult their doctor or pharmacist.
4. Possible side effects
Like all medicines, Zinnat can cause side effects, although not everybody gets them.
Complaints to watch out for
A small number of people taking Zinnat have reported an allergic reaction or potentially severe skin reaction. The symptoms may be:
- Severe allergic reaction. Symptoms include: raised, itchy rash, swelling, sometimes of the face or mouth, which can make breathing difficult.
- Widespread rash, high fever, swollen lymph nodes(DRESS or hypersensitivity syndrome),
- Chest pain associated with an allergic reaction, which can be a sign of allergic myocardial infarction(Kounis syndrome).
- Skin rash, which can develop into blistersand look like small targets(a dark spot in the center surrounded by a lighter ring with a dark ring around the edge).
Widespread skin changes with blisters and peeling skin.This can be a sign of Stevens-Johnson syndrome or toxic epidermal necrolysis (Lyell's disease).
Other complaints to watch out for while taking Zinnat
- Fungal infections.Medicines like Zinnat can cause an overgrowth of Candida (a type of fungus) in the body, leading to a fungal infection (e.g., thrush). The risk of this side effect is higher if Zinnat is taken for a long time.
- Severe diarrhea (pseudomembranous colitis).Medicines like Zinnat can cause inflammation of the colon (large intestine), leading to severe diarrhea, usually with blood and mucus, abdominal pain, and fever.
- Jarisch-Herxheimer reaction.When Zinnat is used to treat Lyme disease (borreliosis), some patients may experience a high fever, chills, muscle and headache, and skin rash. This is known as a Jarisch-Herxheimer reaction. These symptoms usually last from a few hours to a day.
- If the patient experiences any of these symptoms, they should contact their doctor or nurse immediately.
Common side effects
May affect up to 1 in 10 people:
- fungal infections (e.g., with Candida)
- headache
- dizziness
- diarrhea
- nausea
- stomach pain
Common side effects that may be seen in blood tests:
- increased white blood cell count (eosinophilia)
- increased liver enzyme activity
Uncommon side effects
May affect up to 1 in 100 people:
- vomiting
- skin rashes
- Uncommon side effects that may be seen in blood tests:
- decreased platelet count (thrombocytopenia)
- decreased white blood cell count (leukopenia)
- positive Coombs test
Other side effects
Other side effects occur in a very small number of patients, but the exact frequency is unknown:
- severe diarrhea (pseudomembranous colitis)
- allergic reactions
- skin reactions (including severe ones)
- high fever
- yellowing of the whites of the eyes or skin
- liver inflammation
Side effects that may be seen in blood tests:
- rapid breakdown of red blood cells (hemolytic anemia).
Reporting side effects
If the patient experiences any side effects, including any side effects not listed in the leaflet, they should tell their doctor, pharmacist, or nurse. Side effects can be reported directly to the Department of Drug Safety, Ministry of Health, or the pharmaceutical company.
Reporting side effects will help to gather more information on the safety of the medicine.
5. How to store Zinnat
The medicine should be stored out of sight and reach of children.
Do not store above 30°C.
Do not use if the tablets are crushed or damaged in any way.
Do not use this medicine after the expiry date stated on the packaging. The expiry date refers to the last day of the month.
Medicines should not be disposed of via wastewater or household waste. The patient should ask their pharmacist how to dispose of medicines no longer required. This will help protect the environment.
6. Contents of the pack and other information
What Zinnat contains
The active substance of Zinnat is cefuroxime: each coated tablet contains 250 mg of cefuroxime (as cefuroxime axetil).
The other ingredients of Zinnat are: microcrystalline cellulose, sodium lauryl sulfate, croscarmellose sodium, hydrogenated vegetable oil, colloidal anhydrous silica; coating: hypromellose, propylene glycol, Opaspray white M-1-7120J (containing, among others, titanium dioxide (E 171) and sodium benzoate (E 211)).
What Zinnat looks like and contents of the pack
Zinnat, 250 mg, coated tablets are white, capsule-shaped, smooth on one side, and with the inscription “GX ES7” on the other. The tablets are packaged in aluminum/aluminum blisters, in a cardboard box. The pack contains 6, 12, or 24 tablets.
For more detailed information, the patient should contact the marketing authorization holder or parallel importer.
Marketing authorization holder in Greece, the country of export:
Sandoz Pharmaceuticals d.d.
Verovškova 57
SI-1000 Ljubljana
Slovenia
Manufacturer:
GlaxoSmithKline Trading Services Limited
12 Riverwalk
Citywest Business Campus
D24 YK11 Dublin
Ireland
Lek Pharmaceuticals d.d.
Verovškova 57
SI-1526 Ljubljana
Slovenia
Parallel importer:
InPharm Sp. z o.o.
Strumykowa 28/11
03-138 Warsaw
Repackaged by:
InPharm Sp. z o.o. Services sp. k.
Chełmżyńska 249
04-458 Warsaw
Marketing authorization number in Greece, the country of export:41696/5-11-2009
Parallel import authorization number: 193/25
This medicine is authorized in the Member States of the European Economic Area and in the United Kingdom (Northern Ireland) under the following names:
Austria, Belgium, Bulgaria, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Poland, Romania, Slovakia, Slovenia, Spain, Sweden, United Kingdom (Northern Ireland) – Zinnat
Germany – Elobact
Greece – Zinadol
Italy – Oraxim
Portugal – Zipos
Portugal – Zoref
Date of leaflet approval: 28.05.2025
[Information about the trademark]
- Country of registration
- Active substance
- Prescription requiredYes
- Marketing authorisation holder (MAH)Sandoz Pharmaceuticals d.d.
- This information is for reference only and does not constitute medical advice. Always consult a licensed doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
- Alternatives to ZinnatDosage form: Powder, 50 mgActive substance: cefuroximeManufacturer: Biopharma S.r.L. Laboratoires TheaPrescription requiredDosage form: Powder, 1.5 gActive substance: cefuroximeManufacturer: Zakłady Farmaceutyczne POLPHARMA S.A. Zakłady Farmaceutyczne POLPHARMA S.A. Oddział Produkcyjny w DuchnicachPrescription requiredDosage form: Powder, 250 mgActive substance: cefuroximeManufacturer: Zakłady Farmaceutyczne POLPHARMA S.A. Zakłady Farmaceutyczne POLPHARMA S.A. Oddział Produkcyjny w DuchnicachPrescription required
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